Src
Les inhibiteurs de Src sont des composés qui ciblent les kinases de la famille Src, impliquées dans divers processus cellulaires, notamment la croissance, la différenciation et l'angiogenèse. Les kinases Src jouent un rôle crucial dans les voies de signalisation qui favorisent la formation de nouveaux vaisseaux sanguins dans les tumeurs. Inhiber Src peut perturber ces voies, réduisant ainsi l'angiogenèse et la croissance tumorale. Les inhibiteurs de Src sont largement utilisés dans la recherche sur le cancer et le développement thérapeutique. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de Src de haute qualité pour soutenir vos recherches en oncologie, signalisation cellulaire et angiogenèse.
81 produits trouvés pour "Src"
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lavendustin C
CAS :lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.Formule :C14H13NO5Degré de pureté :98.06%Couleur et forme :Yellow To Tan PowderMasse moléculaire :275.26PP1
CAS :PP1 (AGL 1872), a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.Formule :C16H19N5Degré de pureté :99% - 99.88%Couleur et forme :Off-White To Grey SolidMasse moléculaire :281.36WH-4-023
CAS :WH-4-023 (Dual LCK/SRC inhibitor) is a potent and orally active Lck/Src inhibitor. It also potently inhibits SIK.Formule :C32H36N6O4Degré de pureté :98% - 99.75%Couleur et forme :SolidMasse moléculaire :568.671-NM-PP1
CAS :1-NM-PP1 (PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.Formule :C20H21N5Degré de pureté :98% - 98.93%Couleur et forme :White Cyrstalline SolidMasse moléculaire :331.41Masitinib mesylate
CAS :Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;Formule :C29H34N6O4S2Degré de pureté :97.67% - 98.44%Couleur et forme :SolidMasse moléculaire :594.75KX1-004
CAS :KX1-004, a potential protective drug for NIHL, is an effective small molecule inhibitor of Src-PTK.Formule :C16H13FN2O2Degré de pureté :99.39% - ≥95%Couleur et forme :SolidMasse moléculaire :284.29squarunkinA
CAS :squarunkinA is a novel modulator of the UNC119-Cargo Interaction, potently and selectively inhibiting the binding of a myristoylated peptide representing the N-Formule :C25H32F3N5O4Degré de pureté :99.29%Couleur et forme :SolidMasse moléculaire :523.55PP121
CAS :PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Formule :C17H17N7Degré de pureté :98.45% - 99.93%Couleur et forme :SolidMasse moléculaire :319.36Scutellarein
CAS :<p>Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.</p>Formule :C15H10O6Degré de pureté :98.02% - 99.63%Couleur et forme :SolidMasse moléculaire :286.241-Naphthyl PP1 hydrochloride
CAS :1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases v-SrcFormule :C19H20ClN5Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :353.85Periplocin
CAS :Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.Formule :C36H56O13Degré de pureté :99.66% - 99.74%Couleur et forme :SolidMasse moléculaire :696.82Tetramethylcurcumin
CAS :Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it alsoFormule :C25H28O6Degré de pureté :97.69% - 99.94%Couleur et forme :SolidMasse moléculaire :424.49Bafetinib
CAS :<p>Bafetinib (INNO-406): Dual Bcr-Abl/Lyn inhibitor; IC50: 5.8/19 nM; ineffective against T315I mutant, less on c-Kit/PDGFR.</p>Formule :C30H31F3N8ODegré de pureté :94.16% - 99.68%Couleur et forme :SolidMasse moléculaire :576.627-Hydroxy-4H-chromen-4-one
CAS :7-Hydroxy-4H-chromen-4-one (7-hydroxy-4-benzopyrone) is a Src kinase inhibitor (IC50 of <300 μM).Formule :C9H6O3Degré de pureté :97.65%Couleur et forme :SolidMasse moléculaire :162.14XL228
CAS :XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Formule :C22H31N9ODegré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :437.54Tirbanibulin
CAS :Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.Formule :C26H29N3O3Degré de pureté :99.43% - 99.67%Couleur et forme :SolidMasse moléculaire :431.53ENMD-2076
CAS :ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Formule :C21H25N7Degré de pureté :97.63% - ≥95%Couleur et forme :SolidMasse moléculaire :375.47PD-089828
CAS :<p>PD 089828 inhibits FGFR1, PDGFRβ, EGFR (IC50s: 0.15-5.47 μM), and c-Src (IC50: 0.18 μM).</p>Formule :C18H18Cl2N6ODegré de pureté :97.39%Couleur et forme :SolidMasse moléculaire :405.28PD173955
CAS :<p>PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR and</p>Formule :C21H16Cl2N4OSDegré de pureté :98.52% - 98.99%Couleur et forme :SolidMasse moléculaire :443.35AMG-47a
CAS :AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Formule :C29H28F3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :535.56OXSI-2
CAS :OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.Formule :C18H15N3O3SDegré de pureté :98%Couleur et forme :Dark Orange SolidMasse moléculaire :353.39TC-S 7003
CAS :TC-S 7003 (Lck Inhibitor) is a Lck inhibitor with anti-inflammatory activity that inhibits T-cell proliferation and can be used to study arthritis.Formule :C31H30N8ODegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :530.62A 419259 trihydrochloride
CAS :A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).Formule :C29H37Cl3N6ODegré de pureté :99.75% - 99.96%Couleur et forme :SolidMasse moléculaire :592BT424
CAS :BT424, a specific HCK inhibitor, modulates macrophage activation and autophagy in vitro, and mitigates inflammation and renal fibrosis in the UUO model [1].Formule :C22H15BCl2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.08TL02-59
CAS :TL02-59: Fgr inhibitor (IC50=0.03nM), also targets Lyn (0.1nM), Hck (160nM), halts acute myelogenous leukemia growth.Formule :C32H34F3N5O4Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :609.64KB SRC 4
CAS :KB SRC 4 is a selective and potent c-Src inhibitor with antitumour activity that inhibits the growth of cancer cells.CAS 번호13460-73-83-4Formule :C32H23ClN8Degré de pureté :98.83% - 99.34%Couleur et forme :SolidMasse moléculaire :555.03TG 100572 Hydrochloride
CAS :<p>TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.</p>Formule :C26H27Cl2N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :512.43CH6953755
CAS :CH6953755: oral YES1 kinase inhibitor, IC50 1.8 nM, potent, selective, anticancer, halts cell proliferation.Formule :C26H22F2N6O4SDegré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :552.55Src Inhibitor 3
CAS :Src Inhibitor 3 blocks c-Src kinase (IC50 <3 nM CSK HTRF, <4 nM Caliper), boosting T cell growth from receptor signals.Formule :C34H32ClFN8O4Degré de pureté :98.35%Couleur et forme :SolidMasse moléculaire :671.12CGP062464
CAS :CGP062464 is an inhibitor of the tyrosine kinase c-Src, with an IC50 of less than 50 nM. It is utilized in research related to osteoporosis and tumor-induced hypercalcemia.Formule :C18H14N4Couleur et forme :SolidMasse moléculaire :286.331N-Deshydroxyethyl Dasatinib-C3-NH2
CAS :N-Deshydroxyethyl Dasatinib-C3-NH2 is a target protein ligand-linker conjugate, comprising an LCK ligand and a PROTAC linker, designed to recruit E3 ligase. It is utilized in the synthesis of [PROTACSJ11646].Formule :C23H29ClN8OSCouleur et forme :SolidMasse moléculaire :501.05
