IGF-1R
Les inhibiteurs d'IGF-1R sont des composés qui ciblent spécifiquement le récepteur du facteur de croissance analogue à l'insuline 1 (IGF-1R), une tyrosine kinase réceptrice impliquée dans la croissance, le développement et la survie cellulaires. La signalisation IGF-1R joue un rôle important dans la progression du cancer, ce qui rend ces inhibiteurs précieux pour la recherche en oncologie. Chez CymitQuimica, nous proposons des inhibiteurs d'IGF-1R pour soutenir vos recherches en biologie du cancer, endocrinologie et développement de thérapies ciblées.
87 produits trouvés pour "IGF-1R"
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ALK inhibitor 1
CAS :<p>ALK inhibitor 1 is a selective ALK kinase inhibitor.</p>Formule :C23H28BrN7O3SDegré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :562.48AZ7550 hydrochloride
CAS :<p>AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).</p>Formule :C27H32ClN7O2Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :522.04GIP (3-42), human
CAS :<p>Human GIP (3-42) is a peptide antagonist of GIP receptors, affecting insulin regulation and diabetes research.</p>Formule :C214H324N58O63SDegré de pureté :95.73%Couleur et forme :SolidMasse moléculaire :4749.35GIP (human) acetate
<p>GIP (human) acetate boosts insulin, limits gastric acid, affects lipid metabolism, and obesity development.</p>Degré de pureté :98.65%Couleur et forme :SoildRobatumumab
CAS :<p>Robatumumab (Sch 717454) is a fully humanized anti-IGF-1R monoclonal antibody with antitumor activity and antiproliferative activity.</p>Degré de pureté :96.9% (SDS-PAGE); 98.1% (SEC-HPLC) - 96.9% (SDS-PAGE); 98.1% (SEC-HPLC)Couleur et forme :LiquidGanitumab
CAS :<p>Ganitumab (AMG 479) is a potent monoclonal antibody targeting IGF1R with 0.22 nM affinity; used in cancer research.</p>Degré de pureté :100% (SEC-HPLC) - > 95%Couleur et forme :LiquidMasse moléculaire :145.70 kDaMSDC-0602K
CAS :<p>MSDC-0602K, a Ps-TZD, targets PPARγ (IC50: 18.25 μM) and MPC, may help study fatty liver, lipid imbalance, inflammation, and insulin issues.</p>Formule :C19H16KNO5SDegré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :409.5[Pro3]-GIP (Mouse)
<p>GIP receptor blocker, 2.6μM IC50, hinders insulin release, regulates glucose in ob/ob mice, and enhances glucose tolerance.</p>Formule :C225H342N62O64SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4971.62Gastric Inhibitory Peptide (1-42) (porcine) TFA
<p>Gastric Inhibitory Peptide (1-42) (porcine) TFA is a glucose-dependent insulinotropic polypeptide released by intestinal K-cells.</p>Formule :C225H342N60O66S·XCF3COOHCouleur et forme :SolidMasse moléculaire :4975.55IGF-I (24-41)
CAS :<p>IGF-I (24-41) is a fragment of IGF-I, affecting GH activities with anabolic, antioxidant, anti-inflammatory, and cytoprotective properties.</p>Formule :C88H133N27O28Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2017.16cis-NVP-ADW742
CAS :<p>NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.</p>Formule :C28H31N5OCouleur et forme :SolidMasse moléculaire :453.59GIP, human
CAS :<p>Insulinotropic hormone from K-cells, binds GIP receptors, boosts insulin, affects lipids, and has antiapoptotic properties.</p>Formule :C226H338N60O66SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4983.6AVE1642
<p>AVE1642 is a human IgG monoclonal antibody (mAb) that specifically targets CD221/IGF1R. It has the ability to slow the growth of tumor xenografts and extend the survival of tumor-bearing nude mice. AVE1642 is applicable in the study of advanced solid tumors. Recommended isotype control: HumanIgG1kappa, Isotype Control.</p>Couleur et forme :Odour LiquidOI338
<p>OI338 is an orally available, ultralong-acting insulin analogue.</p>Formule :C260H403N65O84S6Couleur et forme :SolidMasse moléculaire :5971.76[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153)
CAS :<p>Insulin Receptor (1142-1153) binds insulin, is a substrate for its kinase, and has research/medical potential.</p>Formule :C72H110N19O33P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1862.67[D-Ala2]-GIP (human)
CAS :<p>Potent GIP receptor agonist with 630 pM EC50; enhances cAMP, glucose control, insulin, cognition in diabetic/obese animals; neuroprotective in PD model.</p>Formule :C226H338N60O66SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4983.58IGF-1R inhibitor-2
CAS :<p>IGF-1R inhibitor-2 blocks the insulin-like growth factor-1 receptor, potentially reversing tumor cell transformation and increasing apoptosis susceptibility.</p>Formule :C24H24FN7O2Couleur et forme :SolidMasse moléculaire :461.501GIP (1-30) amide,human
CAS :<p>GIP (1-30) amide (Human) is a glucose-dependent insulinotropic polypeptide that stimulates insulin secretion, reducing postprandial glycemic issues.</p>Formule :C162H240N40O47SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3531.94Valanafusp alfa
CAS :<p>Valanafusp alfa (AGT-181) is a fusion protein targeting HIR and IDUA for MPS I research.</p>Couleur et forme :LiquidWAY-270250
CAS :<p>WAY-270250 is an IGF-1R/SRC inhibitor.</p>Formule :C18H16N2O2Degré de pureté :99.77%Couleur et forme :SoildMasse moléculaire :292.33ZIGIR
<p>ZIGIR enables insulin-based sorting of pure alpha and beta cells, revealing zinc(II) in human delta cell granules.</p>Formule :C39H40N6O3Degré de pureté :98.34% - 99.32%Couleur et forme :SolidMasse moléculaire :640.77Acetyl Gastric Inhibitory Peptide (human)
CAS :<p>Acetyl Gastric Inhibitory Peptide: improved insulinotropic, antihyperglycemic, for diabetes/obesity research.</p>Formule :C228H340N60O67SCouleur et forme :SolidMasse moléculaire :5025.6Insulin peglispro
CAS :<p>Insulin peglispro (BIL) is a basal insulin with a stable, extended activity and may offer improved blood sugar control.</p>Formule :C370H566N104O110S4Couleur et forme :SolidMasse moléculaire :8359.32(Pro3) GIP, human
CAS :<p>(Pro3) GIP, human: stable hGIPR full agonist, high affinity (Ki/Kd=0.90nM), for obesity-related diabetes research.</p>Formule :C226H338N60O64SCouleur et forme :SolidMasse moléculaire :4951.53DA-JC4
CAS :<p>DA-JC4: dual GLP-1/GIP agonist, for neurological disease research and insulin pathway studies.</p>Formule :C225H346N56O65Couleur et forme :SolidMasse moléculaire :4875.49Macupatide
CAS :<p>Macupatide is a gastric inhibitory polypeptide (GIP) receptor agonist, utilized in research related to antidiabetic applications.</p>Couleur et forme :SolidGIP (1-30) amide, porcine TFA
<p>GIP (1-30) amide, porcine TFA: a full GIP receptor agonist, similar to natural GIP(1-42), stimulates insulin, mildly inhibits gastric acid.</p>Couleur et forme :LiquidNBI-31772
CAS :<p>NBI-31772 (NBI 31772) is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki = 47 nM).</p>Formule :C17H11NO7Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :341.27Teprotumumab
CAS :<p>Teprotumumab: human antibody, inhibits IGF-1R, used for thyroid eye diseases.</p>Degré de pureté :SDS-PAGE:95.2%;SEC-HPLC:99.6%Couleur et forme :LiquidMasse moléculaire :145.62 kDaCixutumumab
CAS :<p>Cixutumumab (IMC-A12), a humanized monoclonal antibody targeting IGF-1R, exhibits high affinity and inhibits ligand-dependent receptor activation, impeding</p>Degré de pureté :98.5% (SDS-PAGE); 97.5% (SEC-HPLC) - 98.5% (SDS-PAGE); 97.5% (SEC-HPLC)Couleur et forme :LiquidInsulin efsitora alfa
CAS :<p>Insulin efsitora alfa(LY-3209590) is an IR agonist and a fusion protein that binds a novel single-chain insulin variant to the structural domain of human IgG Fc</p>Degré de pureté :98.3% (SDS-PAGE); 98.1% (SEC-HPLC) - 98.3% (SDS-PAGE); 98.1% (SEC-HPLC)Couleur et forme :LiquidLDD39
<p>LDD39, a PROTAC targeting the degradation of RET protein, effectively and persistently degrades total RET (tRET) protein in vivo and inhibits phosphorylated RET (pRET) signaling.</p>Formule :C55H59F2N11O6Couleur et forme :SolidMasse moléculaire :1008.12TAK-778
CAS :<p>TAK-778, a derivative of ipriflavone, demonstrates the ability to stimulate bone growth in both in vitro and in vivo models.</p>Formule :C24H28NO7PSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :505.52IGF-I (30-41)
CAS :<p>IGF-I (30-41) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I).</p>Formule :C51H83N19O19Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1266.34TLK19781
CAS :<p>TLK19781 is an insulin receptor modulator.</p>Formule :C33H24Cl2N4O13S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :883.73Proinsulin C-peptide (human)
CAS :<p>C-peptide, a 31-amino acid, links Proinsulin A & B chains for correct folding and function.</p>Formule :C129H211N35O48Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3020.26Insulin α-chain (1-13)
CAS :<p>Insulin alpha-chain peptide, amino acids 1-13, T cell-recognized, posttranslationally modified.</p>Formule :C66H118N20O22S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1639.96PQ401
CAS :<p>PQ401 (IGF-1R Inhibitor II) suppresses autophosphorylation of IGF-1R domain(IC50<1 μM).</p>Formule :C18H16ClN3O2Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :341.79HNMPA
CAS :<p>HNMPA blocks insulin receptor kinase, halting autophosphorylation; no impact on cAMP protein kinase or PKC.</p>Formule :C11H11O4PDegré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :238.18IGF1R/CD221 Protein, Cynomolgus, Recombinant (His)
<p>The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis</p>Couleur et forme :Lyophilized PowderMasse moléculaire :80.59 kDa (alpha subunit) and 19.28 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 48-58 kDa (beta subunit) and 100-115 kDa (alpha subunit) and 130-150 kDa based on Tris-Bis PAGE result.HNMPA-(AM)3
CAS :<p>HNMPA-(AM)3 抑制 ERK 磷酸化的激活以及促促胸腺激素 (PTTH) 刺激蜕皮类固醇产生。 此外，HNMPA-(AM)3 对蜕皮类固醇产生 (IC50=14.2 μM) 和胰岛素受体活性 (IC50=14.2 μM 和 200 μM，在蚊子和哺乳动物中分别) 具有抑制作用。</p>Formule :C20H23O10PDegré de pureté :97.22%Couleur et forme :SolidMasse moléculaire :454.36IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated
<p>The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis</p>Couleur et forme :Lyophilized PowderMasse moléculaire :105.8 kDa (alpha subunit) and 23 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 110-120 kDa (alpha subunit) and 52-55 kDa (beta subunit) based on Tris-Bis PAGE result.IGF1R/CD221 Protein, Mouse, Recombinant (His)
<p>IGF1R/CD221 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Degré de pureté :> 95% as determined by Bis-Tris PAGE > 90% as determined by HPLC - > 95% as determined by Bis-Tris PAGE > 90% as determined by HPLCCouleur et forme :Lyophilized PowderMasse moléculaire :80.72+23.0 kDa (predicted); 110-140 kDa and 50-65 kDa, corresponding to the α subunit and β subunit respectively (reducing condition, due to glycosylation)IGF1R/CD221 Protein, Human, Recombinant (His & Avi)
<p>The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis</p>Couleur et forme :Lyophilized PowderMasse moléculaire :105.8 kDa (alpha subunit) and 23 kDa (beta subunit) (predicted). Due to glycosylation, the protein migrates to 110-120 kDa(alpha subunit) and 52-55 kDa(beta subunit) based on Tris-Bis PAGE result.Ceritinib
CAS :<p>Ceritinib (LDK378) is an ALK inhibitor with selective, ATP-competitive, and oral activity. Ceritinib has antitumor activity. Cost-effective and quality-assured.</p>Formule :C28H36ClN5O3SDegré de pureté :98.52% - 99.77%Couleur et forme :SolidMasse moléculaire :558.14MID-1
CAS :<p>MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.</p>Formule :C12H11N3O4SDegré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :293.3Picropodophyllin
CAS :<p>Picropodophyllin (PPP) is a selective IGF-1R inhibitor with IC50 of 1 nM, not affecting other growth factor receptors.</p>Formule :C22H22O8Degré de pureté :98.88% - 99.62%Couleur et forme :SolidMasse moléculaire :414.41NVP-AEW541
CAS :<p>NVP-AEW541 (AEW541), a potent inhibitor of IGF-1R(IC50=150 nM) and InsR(IC50=140 nM), exhibits excellent efficiency and specificity for IGF-1R in a cell-based</p>Formule :C27H29N5ODegré de pureté :98.7% - 99.86%Couleur et forme :SolidMasse moléculaire :439.55BMS-536924
CAS :<p>BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for</p>Formule :C25H26ClN5O3Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :479.96MSDC 0160
CAS :<p>MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.</p>Formule :C19H18N2O4SDegré de pureté :98.11% - 99.53%Couleur et forme :SolidMasse moléculaire :370.42NVP-TAE 226
CAS :<p>NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.</p>Formule :C23H25ClN6O3Degré de pureté :98.07% - 98.78%Couleur et forme :SolidMasse moléculaire :468.94MAZ51
CAS :<p>MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.</p>Formule :C21H18N2ODegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :314.38XL228
CAS :<p>XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).</p>Formule :C22H31N9ODegré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :437.54Ceritinib dihydrochloride
CAS :<p>Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable, ATP-competitive inhibitor of ALK tyrosine kinase with antitumour effect.</p>Formule :C28H38Cl3N5O3SDegré de pureté :99.85% - 99.99%Couleur et forme :SolidMasse moléculaire :631.06NT157
CAS :<p>NT157, a small tyrphostin, inhibits IRS, IGF-1R, and STAT3 in TME, reducing cancer cell survival.</p>Formule :C16H14BrNO5SDegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :412.26Ginsenoside Rg5
CAS :<p>Ginsenoside Rg5 shows promise for Alzheimer's, reduces inflammation, and aids vascular health without side effects.</p>Formule :C42H70O12Degré de pureté :98% - 99.65%Couleur et forme :SolidMasse moléculaire :767Insulin(cattle)
CAS :<p>Insulin(cattle) is a peptide hormone that promotes glycogen synthesis. Insulin) has hypoglycemic activity. Cost-effective and quality-assured.</p>Formule :C254H377N65O75S6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :5733.49GSK1838705A
CAS :<p>GSK1838705A: IGF-1R inhibitor (IC50=2.0nM), IR (1.6nM), ALK (0.5nM), minimal other kinase impact.</p>Formule :C27H29FN8O3Degré de pureté :98.89% - >99.99%Couleur et forme :SolidMasse moléculaire :532.57AZ7550
CAS :<p>AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).</p>Formule :C27H31N7O2Degré de pureté :97.07% - 99.75%Couleur et forme :SolidMasse moléculaire :485.58NVP-ADW742
CAS :<p>NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl</p>Formule :C28H31N5ODegré de pureté :96.14% - 98.70%Couleur et forme :SolidMasse moléculaire :453.58NBI-31772 hydrate
<p>NBI-31772 hydrate blocks IGF and IGFBPs binding, freeing IGF-I with Ki 1-24 nM; it has anxiolytic and antidepressant effects.</p>Formule :C17H13NO8Couleur et forme :SolidMasse moléculaire :372.82Linsitinib
CAS :<p>OSI-906 (Linsitinib) is an oral inhibitor of IGF-1R with anti-cancer properties, potentially halting tumor growth and inducing cell death.</p>Formule :C26H23N5ODegré de pureté :99.71% - ≥95%Couleur et forme :SolidMasse moléculaire :421.49AZD-3463
CAS :<p>AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.</p>Formule :C24H25ClN6ODegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :448.95BRD7552
CAS :<p>BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression. BRD7552 increases PDX1 expression in mouse αTC cells but not βTC cells.</p>Formule :C33H33N3O15Degré de pureté :>99.99% - ≥98%Couleur et forme :SolidMasse moléculaire :711.63Sari 59-801
CAS :Sari 59-801 is a novel, orally effective hypoglycemic compound that appears to act largely by stimulation of insulin release.Formule :C18H23N3O2Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :313.39PQ401 hydrochloride (196868-63-0(free base))
<p>PQ401 inhibits autophosphorylation of IGF-1R domain with IC50 of <1 μM.</p>Formule :C18H17Cl2N3O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :378.25AG1024
CAS :<p>AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).</p>Formule :C14H13BrN2ODegré de pureté :98% - 99.37%Couleur et forme :SolidMasse moléculaire :305.17Indirubin Derivative E804
CAS :<p>Indirubin Derivative E804 is a potent insulin-like growth factor type 1 receptor (IGF1R) inhibitor with potential antitumor activity.</p>Formule :C20H19N3O4Degré de pureté :98.54%Couleur et forme :SolidMasse moléculaire :365.38GSK1904529A
CAS :<p>GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .</p>Formule :C44H47F2N9O5SDegré de pureté :98.2% - 99.38%Couleur et forme :SolidMasse moléculaire :851.96Anti-IGFBP2 Antibody (M14)
<p>Anti-IGFBP2 Antibody (M14) is a human monoclonal antibody inhibitor that binds with high affinity to IGFBP2 and prevents its interaction with IGF1. Additionally, Anti-IGFBP2 Antibody (M14) can inhibit the recruitment of human endothelial cells, thereby obstructing tumor progression in human metastatic cancers.</p>Couleur et forme :Odour LiquidFigitumumab
CAS :<p>Figitumumab is a potent anti-IGF1R mAb (IC50=1.8 nM) showing promise in advanced lung squamous cell carcinoma.</p>Degré de pureté :95%Couleur et forme :LiquidDusigitumab
CAS :<p>Dusigitumab (MEDI573) is a fully humanised monoclonal antibody targeting IGF1/IGF2, inhibiting IGF1/IGF2-induced IGF-1R phosphorylation.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidVeligrotug
CAS :<p>Veligrotug is an IV anti-IGF-1R antibody for thyroid eye disease, reducing diplopia and orbital inflammation, supporting autoimmune ophthalmopathy research.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidS961
CAS :<p>S961: High-affinity IR antagonist; IC50: HIR-A 0.048 nM, HIR-B 0.027 nM, HIGF-IR 630 nM.</p>Formule :C211H297N55O71S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4804.13BMS-754807
CAS :<p>BMS-754807 is an oral IGF-1R/InsR inhibitor with potential anti-cancer properties.</p>Formule :C23H24FN9ODegré de pureté :99.69% - 99.94%Couleur et forme :SolidMasse moléculaire :461.49AZ12253801
CAS :<p>AZ12253801 is a type 1 insulin-like growth factor receptor (IGF-1R) inhibitor.</p>Formule :C21H22N8ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :402.45BM-131246
CAS :<p>BM-131246 is an orally available and antidiabetic active thiazolidinedione derivative for the study of diabetes.</p>Formule :C22H20N2O4SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :408.47D-(+)-Sorbose
CAS :<p>D-(+)-Sorbose, an enantiomer inhibiting disaccharidase, lowers glucose and insulin post-meal in rats, possibly preventing diabetes.</p>Formule :C6H12O6Couleur et forme :SolidMasse moléculaire :180.16KU14R
CAS :<p>KU14R is a new I(3)-R antagonist, which selectively blocks the insulin secretory response to imidazolines.</p>Formule :C13H14N2ODegré de pureté :98%Couleur et forme :White SolidMasse moléculaire :214.26NT219
CAS :<p>NT219 is a dual inhibitor of insulin receptor substrate 1/2 (IRS1/2) and STAT3 that enhances the aggregation of misfolded prion proteins NT219 Effects.</p>Formule :C16H14BrNO5SDegré de pureté :98.06% - 99.72%Couleur et forme :SolidMasse moléculaire :412.26I-OMe-Tyrphostin AG 538
CAS :<p>I-OMe-Tyrphostin AG 538: IGF-1R & PI5P4Kα inhibitor, ATP-competitive, IC50 of 1 µM, targets IGF-1R pathway, cytotoxic in nutrient-poor PANC1 cells.</p>Formule :C17H12INO5Degré de pureté :98.23%Couleur et forme :SolidMasse moléculaire :437.19Protonstatin-1
CAS :<p>Protonstatin-1: treats hypoglycemia & Alzheimer's, inhibits IGFIR kinase, used in cancer studies.</p>Formule :C8H5NO2S2Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :211.26BMS-695735
CAS :<p>BMS-695735: benzimidazole, inhibits IGF-1 receptor, broad antitumor effects, affects CYP3A4, low solubility, binds plasma proteins.</p>Formule :C26H31ClFN7OCouleur et forme :SolidMasse moléculaire :512.02Tyrphostin AG 538
CAS :<p>Tyrphostin AG 538 is a chalcone compound, an IGF-1 receptor kinase inhibitor (IC₅0 : for 400 nM) that is potent, cell-permeable, reversible, and competitive.</p>Formule :C16H11NO5Degré de pureté :98.75%Couleur et forme :SoildMasse moléculaire :297.26IGF-1R inhibitor-4
CAS :<p>IGF-1Rinhibitor-4 (compound 22) is a potent inhibitor of IGF-1R, demonstrating an inhibition rate of 63% at a concentration of 10 μM. This compound plays a significant role in cancer research.</p>Formule :C13H15ClN4OCouleur et forme :SolidMasse moléculaire :278.737CL-A3-7
CAS :<p>CL-A3-7 is a viral-cell fusion inhibitor targeting the RSVF protein. It functions by blocking the interaction between the virus and the host's IGF1R, effectively inhibiting the infection of both wild-type and K394R mutant strains of RSV. This compound is suitable for use in antiviral drug development and resistance studies related to RSV.</p>Formule :C24H22Br2F2N2O3Couleur et forme :SolidMasse moléculaire :584.25AGL-2263
CAS :<p>AGL-2263 is a blocker of insulin receptor (IR)</p>Formule :C17H10N2O5Couleur et forme :SolidMasse moléculaire :322.27
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