IGF-1R
Les inhibiteurs d'IGF-1R sont des composés qui ciblent spécifiquement le récepteur du facteur de croissance analogue à l'insuline 1 (IGF-1R), une tyrosine kinase réceptrice impliquée dans la croissance, le développement et la survie cellulaires. La signalisation IGF-1R joue un rôle important dans la progression du cancer, ce qui rend ces inhibiteurs précieux pour la recherche en oncologie. Chez CymitQuimica, nous proposons des inhibiteurs d'IGF-1R pour soutenir vos recherches en biologie du cancer, endocrinologie et développement de thérapies ciblées.
106 produits trouvés pour "IGF-1R".
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Insulin Aspart
CAS :Insulin Aspart is a rapid-acting insulin analog with faster absorption than human insulin, improving postprandial glycemic control.Degré de pureté :99.86%Couleur et forme :White Solid[Pro3]-GIP (Mouse)
GIP receptor blocker, 2.6μM IC50, hinders insulin release, regulates glucose in ob/ob mice, and enhances glucose tolerance.Formule :C225H342N62O64SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4971.62AVE1642
AVE1642 is a human IgG monoclonal antibody (mAb) that specifically targets CD221/IGF1R. It has the ability to slow the growth of tumor xenografts and extend the survival of tumor-bearing nude mice. AVE1642 is applicable in the study of advanced solid tumors. Recommended isotype control: HumanIgG1kappa, Isotype Control.Couleur et forme :Odour LiquidIGF-I (30-41)
CAS :IGF-I (30-41) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I).Formule :C51H83N19O19Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1266.34TLK19781
CAS :TLK19781 is an insulin receptor modulator.Formule :C33H24Cl2N4O13S4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :883.73OI338
OI338 is an orally available, ultralong-acting insulin analogue.Formule :C260H403N65O84S6Couleur et forme :SolidMasse moléculaire :5971.76Proinsulin C-Peptide (55-89), human
CAS :Proinsulin, insulin's precursor, has A and B chains linked by a 31 amino acid C-peptide. Enzymes cleave it, yielding insulin and C-peptide.Formule :C153H259N49O52Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3616.99[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153)
CAS :Insulin Receptor (1142-1153) binds insulin, is a substrate for its kinase, and has research/medical potential.Formule :C72H110N19O33P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1862.67Gastric Inhibitory Peptide (1-42) (porcine) TFA
Gastric Inhibitory Peptide (1-42) (porcine) TFA is a glucose-dependent insulinotropic polypeptide released by intestinal K-cells.Formule :C225H342N60O66S·XCF3COOHCouleur et forme :White SolidMasse moléculaire :4975.55[D-Ala2]-GIP (human)
CAS :Potent GIP receptor agonist with 630 pM EC50; enhances cAMP, glucose control, insulin, cognition in diabetic/obese animals; neuroprotective in PD model.Formule :C226H338N60O66SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :4983.58Macupatide
CAS :Macupatide is a gastric inhibitory polypeptide (GIP) receptor agonist, utilized in research related to antidiabetic applications.Couleur et forme :SolidGIP (1-30) amide,human
CAS :GIP (1-30) amide (Human) is a glucose-dependent insulinotropic polypeptide that stimulates insulin secretion, reducing postprandial glycemic issues.Formule :C162H240N40O47SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3531.94cis-NVP-ADW742
CAS :NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.Formule :C28H31N5OCouleur et forme :SolidMasse moléculaire :453.59LDD39
LDD39, a PROTAC targeting the degradation of RET protein, effectively and persistently degrades total RET (tRET) protein in vivo and inhibits phosphorylated RET (pRET) signaling.Formule :C55H59F2N11O6Couleur et forme :SolidMasse moléculaire :1008.12IGF-1R inhibitor-2
CAS :IGF-1R inhibitor-2 blocks the insulin-like growth factor-1 receptor, potentially reversing tumor cell transformation and increasing apoptosis susceptibility.Formule :C24H24FN7O2Couleur et forme :SolidMasse moléculaire :461.501WAY-270250
CAS :WAY-270250 is an IGF-1R/SRC inhibitor.Formule :C18H16N2O2Degré de pureté :99.97%Couleur et forme :Green SolidMasse moléculaire :292.33LAGIPRA peptide
LAGIPRA peptide is a long-acting agonist of GIP1R. It improves insulin sensitivity by enhancing glucose handling and reduces circulating branched-chain amino acids (BCAA) and keto acids. LAGIPRA peptide holds potential for research in type 2 diabetes.Insulin peglispro
CAS :Insulin peglispro (BIL) is a basal insulin with a stable, extended activity and may offer improved blood sugar control.Formule :C370H566N104O110S4Couleur et forme :SolidMasse moléculaire :8359.32ZIGIR
ZIGIR enables insulin-based sorting of pure alpha and beta cells, revealing zinc(II) in human delta cell granules.Formule :C39H40N6O3Degré de pureté :98.34% - 99.32%Couleur et forme :Pink SolidMasse moléculaire :640.77(Pro3) GIP, human
CAS :(Pro3) GIP, human: stable hGIPR full agonist, high affinity (Ki/Kd=0.90nM), for obesity-related diabetes research.Formule :C226H338N60O64SCouleur et forme :SolidMasse moléculaire :4951.53
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![[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153)](https://static.cymitquimica.com/products/TM/thumb-webp/TP1259.webp)
