Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
1427 produits trouvés pour "Autophagie"
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Obatoclax
CAS :<p>Obatoclax (GX15-070), a pan-BCL-2 inhibitor (Ki 220 nM) induces autophagy, degrades cyclin D1, and has anti-cancer/antiparasitic properties.</p>Formule :C20H19N3ODegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :317.38LS2265
CAS :<p>LS2265, a fenofibrate derivative with a taurine modification, effectively induces the proliferation of peroxisomes in rat liver cells.</p>Formule :C19H20ClNO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :425.88STK683963
CAS :<p>STK683963 activates ATG4B, mediates redox regulation, and aids cancer research.</p>Formule :C12H8FN3O2SCouleur et forme :SolidMasse moléculaire :277.27AGN 205327
CAS :<p>AGN 205327 is a potent synthetic RAR agonist,showing selective RAR activation without RXR inhibition for retinoid research.</p>Formule :C24H26N2O3Degré de pureté :99.45% - 99.71%Couleur et forme :SolidMasse moléculaire :390.47SB02024
CAS :<p>SB02024 inhibits VPS34, boosts cGAS-STING, hinders autophagy, and shrinks breast cancer xenografts; enhances Sunitinib/Erlotinib efficacy.</p>Formule :C16H22F3N3O2Couleur et forme :SolidMasse moléculaire :345.36Nicodicosapent
CAS :<p>Nicodicosapent is a fatty acid niacin conjugate that inhibits SREBP, a regulator of cholesterol metabolism.</p>Formule :C28H39N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :449.63HF51116
CAS :<p>HF51116 blocks XCR4, hinders SDF-1α cell effects & HIV-1; potential for HIV, stem cells, cancer spread.</p>Formule :C29H46N8OCouleur et forme :SolidMasse moléculaire :522.73CC214-2
CAS :<p>CC214-2: strong dual mTORC1/2 inhibitor, blocks autophagy, may shorten TB duration.</p>Formule :C20H25N5O3Couleur et forme :SolidMasse moléculaire :383.44AMDE-1
CAS :<p>AMDE-1, an autophagy modulator, triggers Atg5-dependent autophagy, recruits Atg16, and induces LC3 lipidation.</p>Formule :C18H8ClF6N3Degré de pureté :90%Couleur et forme :SolidMasse moléculaire :415.72AS1708727
CAS :<p>AS1708727 inhibits Foxo1, reducing blood sugar and triglycerides by altering gene expression.</p>Formule :C24H24Cl2N2O2Couleur et forme :SolidMasse moléculaire :443.37Aliskiren fumarate
CAS :<p>Oral renin inhibitor Aliskiren fumarate treats hypertension; IC50: 1.5 nM. Useful for cardiovascular and cancer cachexia research.</p>Formule :C34H57N3O10Couleur et forme :SolidMasse moléculaire :667.83ALLO-1
CAS :<p>ALLO-1, vital for autophagy, aids in engulfing paternal organelles by binding to worm LC3, LGG-1, via its LIR motif.</p>Formule :C17H15ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :314.77MF-095
CAS :<p>MF-095 is a control probe for MF-094, which is a potent inhibitor of ubiquitin specific protease 30.</p>Formule :C27H31N3O4SCouleur et forme :SolidMasse moléculaire :493.62Elliptinium acetate
CAS :<p>Elliptinium acetate (NSC 264137), a cytotoxic DNA intercalator for cancer research, targets L1210 cells.</p>Formule :C20H20N2O3Couleur et forme :SolidMasse moléculaire :336.38Rimacalib
CAS :<p>Rimacalib is an inhibitor of Ca2+/calmodulin-dependent protein kinase II (IC50s: ~1 μM for CaMKIIα and ~30 μM for CaMKIIγ).</p>Formule :C22H23FN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :394.44DK-1-49
CAS :<p>DK-1-49 is an autophagonizer. It causes accumulation of autophagy-associated LC3-II and enhanced levels of autophagosomes and acidic vacuoles.</p>Formule :C28H31N5O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :549.71rac-NBI-74330
CAS :<p>rac-NBI-74330 is an effective and selective CXCR3 antagonist.</p>Formule :C32H27F4N5O3Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :605.58(-)-Talarozole
CAS :<p>(-)-Talarozole is a potent retinoic acid metabolism inhibitor.</p>Formule :C21H23N5SCouleur et forme :SolidMasse moléculaire :377.51TUN-92046
CAS :<p>TUN-92046 is a permeable alpha-ketoglutarate analog that blocks harmful autophagy in cardiomyopathy.</p>Formule :C7H10O5Degré de pureté :95.48% - 98.58%Couleur et forme :SolidMasse moléculaire :174.15GPR35 agonist 1
CAS :<p>GPR35 agonist 1 is a highly effective and specific GPR35/CXCR8 agonist (EC50: 5.8 nM).</p>Formule :C10H4BrN5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :354.07Glaucocalyxin B
CAS :<p>Glaucocalyxin B is a diterpenoid isolated from Rabdosia japonica with anticancer and antitumor activity. It decreases the growth of HL-60 cells (IC50: 5.86 μM).</p>Formule :C22H30O5Degré de pureté :99.13% - 99.35%Couleur et forme :SolidMasse moléculaire :374.47FKBP51F67V-selective antagonist Ligand2
CAS :<p>FKBP51F67V-selective antagonist Ligand2 (example 3-3), a potent ligand, selectively binds to the FKBP51 F67V variant, with no affinity for wild-type FKBP51 or</p>Formule :C43H56N2O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :760.91VUF5834
CAS :<p>VUF5834 is a full inverse agonist of CXCR3 N3.35A.</p>Formule :C31H41N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :515.69PS372424
CAS :<p>PS372424 is a specific agonist of human CXCR3, with anti-inflammatory activity.</p>Formule :C33H44N6O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :588.74ATG7-IN-2
CAS :<p>ATG7-IN-2 inhibits ATG7 protein with 0.089 μM IC50 and suppresses autophagy marker LC3B.</p>Formule :C11H16N6O7SCouleur et forme :SolidMasse moléculaire :376.35LRRK2-IN-10
CAS :<p>LRRK2-IN-10 (compound 34) is a potent, mutation-selective, brain-penetrant inhibitor targeting G2019S-LRRK2 kinase with IC50 values of 11 nM for G2019S-LRRK2</p>Formule :C20H15N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :341.37AZ10397767
CAS :<p>AZ10397767: Potent CXCR2 blocker (IC50=1nM); lowers neutrophil infiltration in tumors in vitro/in vivo.</p>Formule :C15H14ClFN4O2S2Couleur et forme :SolidMasse moléculaire :400.88(R)-Hydroxychloroquine
CAS :<p>(R)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine. Hydroxychloroquine is an agent of synthetic antimalarial.</p>Formule :C18H26ClN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :335.87AGN 205728
CAS :<p>AGN 205728 is a potent and selective RARγ antagonist (Ki: 3 nM; IC95: 0.6 nM) and has no inhibition on RARα and RARβ.</p>Formule :C29H27NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :437.53SCH 546738
CAS :<p>SCH 546738 is an orally available, selective and potent CXCR3 antagonist that attenuates the development of autoimmune diseases and delays graft rejection.</p>Formule :C23H31Cl2N7ODegré de pureté :98.67%Couleur et forme :SolidMasse moléculaire :492.45AC-55649
CAS :<p>AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9.</p>Formule :C21H26O2Degré de pureté :99.98%Couleur et forme :SolidMasse moléculaire :310.43AL 8697
CAS :<p>AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.</p>Formule :C21H21F3N4ODegré de pureté :99.55% - 99.89%Couleur et forme :SolidMasse moléculaire :402.41FR 167653 free base
CAS :<p>FR 167653 is an oral p38 MAPK inhibitor for inflammation, trauma, ischemia relief; it suppresses TNF-α, IL-1β.</p>Formule :C24H18FN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :427.43Sulfosuccinimidyl oleate
CAS :<p>Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells.</p>Formule :C22H37NO7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.6SRT3190
CAS :<p>SRT3190 is an antagonist of CXCR2.</p>Formule :C18H23F2N5O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :475.53Ipsalazide
CAS :<p>Ipsalazide is a novel salicylazosulfapyridine analog for the treatment of inflammatory bowel disease.</p>Formule :C16H11N3Na2O6Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :387.25GLPG2451
CAS :<p>GLPG2451 potentiates F508del CFTR at low temp (EC50: 11.1 nM), aiding cystic fibrosis treatment.</p>Formule :C16H16F3N3O5SCouleur et forme :SolidMasse moléculaire :419.38ACT-660602
CAS :<p>ACT-660602: Oral CXCR3 blocker, T-cell migration inhibitor, effective in acute lung injury models, potential for autoimmune research. IC50: 204 nM.</p>Formule :C20H20F6N8OSCouleur et forme :SolidMasse moléculaire :534.48Omeprazole Sodium
CAS :<p>Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.</p>Formule :C17H18N3NaO3SDegré de pureté :99.84%Couleur et forme :Clear In WaterMasse moléculaire :367.4SMER18
CAS :<p>SMER18, a small molecule enhancer of rapamycin, acts as an mTOR-independent inducer of autophagy and can be used to study neurodegenerative diseases.</p>Formule :C16H14ClNO2Degré de pureté :97.27%Couleur et forme :SolidMasse moléculaire :287.74Ivacaftor hydrate
CAS :<p>Ivacaftor hydrate is an orally bioavailable CFTR potentiator. It also is used for cystic fibrosis treatment.</p>Formule :C24H30N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :410.514CXCR4 antagonist 5
CAS :<p>CXCR4 antagonist with IC50 of 8.8 nM, inhibits CXCL12-induced calcium increase and chemotaxis, with good safety and minimal CYP, hERG impact.</p>Formule :C21H30N6Couleur et forme :SolidMasse moléculaire :366.5VUF10132
CAS :<p>VUF10132 is a full inverse CXCR3 N3.35A agonist.</p>Formule :C19H13BrCl4N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :523.03Poloppin
CAS :<p>Poloppin modulates polo-like kinases, targets mutant KRAS, and enhances Crizotinib's effects against KRAS-mutant cancers.</p>Formule :C20H15BrF3NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.24PF-06455943
CAS :<p>PF-06455943: LRRK2 inhibitor, IC50=3nM, PET radioligand, used for ADME/neuro PK & Parkinson's research.</p>Formule :C17H14FN5OCouleur et forme :SolidMasse moléculaire :323.32Ivacaftor benzenesulfonate
CAS :<p>Ivacaftor benzenesulfonate used for cystic fibrosis treatment. is an orally bioavailable CFTR potentiator.</p>Formule :C30H34N2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :550.67eIF4A3-IN-2
CAS :<p>eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM.</p>Formule :C25H19Br2ClN4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :602.71Ralimetinib
CAS :<p>Ralimetinib blocks MK2 phosphorylation at Thr334 without affecting p38α MAPK or JNK. It is an ATP-competitive inhibitor of p38 MAPK α/β (IC50 5.3/3.2 nM).</p>Formule :C24H29FN6Degré de pureté :99.16% - 99.21%Couleur et forme :SolidMasse moléculaire :420.53PF-06371900
CAS :<p>PF-06371900 is a potent and highly selective inhibitor of leucine-rich repeat kinase 2 (LRRK2).</p>Formule :C17H16N6O2SCouleur et forme :SolidMasse moléculaire :368.41Olacaftor
CAS :<p>Olacaftor, also known as VX-440, is a protein modulator of cystic fibrosis transmembrane regulator (CFTR).</p>Formule :C29H34FN3O4SCouleur et forme :SolidMasse moléculaire :539.66Lamotrigine isethionate
CAS :<p>Water-soluble salt of lamotrigine . Displays anticonvulsant effects and inhibits glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents.</p>Formule :C11H13Cl2N5O4SCouleur et forme :SolidMasse moléculaire :382.22SR 3677 dihydrochloride
CAS :<p>Potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively).</p>Formule :C22H26Cl2N4O4Couleur et forme :SolidMasse moléculaire :481.37NSC 33994
CAS :<p>NSC 33994 is a selective inhibitor of JAK2 (IC50 = 60 nM). It also shows no effect on Src and TYK2 tyrosine kinase activity at a concentration of 25 μM.</p>Formule :C28H42N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.65CXCR4 modulator-2
CAS :<p>CXCR4 modulator-2 (Z7R) has high potency (IC50: 1.25 nM), stable in mouse serum (t1/2=77.1 min), and anti-inflammatory in mice.</p>Formule :C21H32N8O2Couleur et forme :SolidMasse moléculaire :428.53SMYD3-IN-2
<p>SMYD3-IN-2, a cancer research chemical, inhibits SMYD3 (IC50 0.81 μM) and BGC823 (IC50 0.75 μM), inducing fatal autophagy in gastric cancer.</p>Formule :C26H21BrN2O4Couleur et forme :SolidMasse moléculaire :505.36Antitumor agent-81
CAS :<p>Antitumor agent-81, a P62-RNF168 agonist, reduces H2A ubiquitination, hinders DNA repair, and inhibits tumor growth.</p>Formule :C19H19N7O3Couleur et forme :SolidMasse moléculaire :393.4ROC-325
CAS :<p>ROC-325: orally active autophagy inhibitor with anticancer effects, induces kidney cancer cell death; selective action.</p>Formule :C28H27ClN4OSDegré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :503.06MPM-1
<p>MPM-1, a marine mimic, induces rapid necrotic-like death in cancer cells, disrupts autophagy, and causes lysosomal swelling.</p>Formule :C34H44F6N4O7Couleur et forme :SolidMasse moléculaire :734.73(Rac)-AZD 6482
CAS :<p>(Rac)-AZD 6482 is the racemate of AZD 6482. AZD 6482 is a potent and selective inhibitor of p110β (IC50 of 0.69 nM).</p>Formule :C22H24N4O4Couleur et forme :SolidMasse moléculaire :408.45K67
CAS :<p>K67 competitively inhibits the interaction between Nrf2-ETGE and Keap1 and can be used to study cancer.</p>Formule :C29H30N2O7S2Degré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :582.69CCT128930
CAS :<p>'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'</p>Formule :C18H20ClN5Degré de pureté :99.07% - 99.18%Couleur et forme :SolidMasse moléculaire :341.84SR12418
CAS :<p>SR12418 is a specific synthetic ligand for REV-ERBα (IC50 = 68 nM) and REV-ERBβ (IC50 = 119 nM) in TR-FRET assays. inhibits IL-17A expression in EL4 cells.</p>Formule :C31H30FNO3Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :483.57IT1t
CAS :<p>IT1t inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. is a potent CXCR4 antagonist.</p>Formule :C21H34N4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :406.65CUR5g
CAS :<p>CUR5g is an autophagy inhibitor that inhibits migration and colony formation in A549 cells.</p>Formule :C22H20N2O2Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :344.41Amsacrine
CAS :<p>Amsacrine (AMSA) (mAMSA) an antineoplastic agent which can intercalate into the DNA of tumor cells.</p>Formule :C21H19N3O3SDegré de pureté :99.2%Couleur et forme :Yellow Crystalline Powder SolidMasse moléculaire :393.46Autophagy inducer 3
CAS :<p>Autophagy Inducer 3 triggers selective cancer cell death via autophagy, sparing healthy cells.</p>Formule :C24H43NO2Couleur et forme :SolidMasse moléculaire :377.6Dinoprost
CAS :<p>Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.</p>Formule :C20H34O5Degré de pureté :97.94% - 98.04%Couleur et forme :White To Off-White Crystalline SolidMasse moléculaire :354.48AMG 487 (S-enantiomer)
CAS :<p>AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an CXCR3 antagonist.</p>Formule :C32H28F3N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :603.59Evogliptin
CAS :<p>Evogliptin (DA-1229) is an oral DPP4 inhibitor effective in reducing blood sugar and liver inflammation.</p>Formule :C19H26F3N3O3Couleur et forme :SolidMasse moléculaire :401.42ATG7-IN-3
CAS :<p>ATG7-IN-3, or compound 18, is an ATG7 inhibitor with a 0.048 μM IC50, blocking autophagy and LC3B puncta in H4 cells.</p>Formule :C11H16N6O5S2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :376.41Xantocillin
CAS :<p>Xanthocillin is a marine agent. Xanthocillin also induces autophagy through inhibition of the MEK/ERK pathway.</p>Formule :C18H12N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :288.3YM-155 hydrochloride
CAS :<p>Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1].</p>Formule :C20H19ClN4O3Couleur et forme :SolidMasse moléculaire :398.85OSU-53
CAS :<p>OSU-53 is an AMPK activator, inhibiting mTOR signaling and autophagy stimulation. OSU-53 also activates mutations in RAS or BRAF.</p>Formule :C25H24F3N3O6S2Couleur et forme :SolidMasse moléculaire :583.6ABTL-0812
CAS :<p>ABTL-0812 induces endoplasmic reticulum (ER) stress-mediated autophagy, and with anti-cancer activity.</p>Formule :C18H32O3Couleur et forme :SolidMasse moléculaire :296.44HF50731
CAS :<p>HF50731 is a CXCR4 antagonist with high binding affinity (IC50: 19.8 nM) and inhibits calcium mobilization, cell migration, and HIV-1 (IC50: 1.5 nM).</p>Formule :C26H46N4Couleur et forme :SolidMasse moléculaire :414.67(Rac)-BL-918
CAS :<p>(Rac)-BL-918 is the racemic form of BL-918. BL-918 is an effective activator of UNC-51-like kinase 1 (ULK1) (EC₅₀ = 24.14 nM), Parkinson's disease.</p>Formule :C23H15F8N3OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :533.44FAAH inhibitor 1
CAS :<p>FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.</p>Formule :C24H23N3O3S3Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :497.65GSK3-IN-3
CAS :<p>GSK3-IN-3 is a mitochondrial autophagy (mitophagy) inducer and GSK-3 inhibitor (IC50: 3.01 μM) that induces parkin-dependent mitochondrial autophagy.</p>Formule :C24H35N3O4Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :429.55MDK-6983
CAS :<p>MDK-6983 (MDK-6983) is an inhibitor of autophagy and disrupts the dynamics of actin cytoskeleton in human melanoma cells.</p>Formule :C22H18Cl2N2O3Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :429.3MRT-68601 HCl
CAS :<p>MRT-68601 HCl, a potent TBK1 (TANK-binding kinase-1), inhibits the formation of autophagosomes in lung cancer cells.</p>Formule :C25H34N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :450.58YOK-2204
CAS :<p>YOK-2204 is a ligand for the p62-ZZ domain and activates p62-dependent selective autophagy. It is also applicable in the design of AUTOTACs.</p>Formule :C28H35NO4Couleur et forme :SolidMasse moléculaire :449.58FC131
CAS :<p>CXCR4 antagonist</p>Formule :C36H47N11O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :729.83SA72
CAS :<p>SA72 is a highly selective inhibitor of fatty acid amide hydrolase (FAAH).</p>Formule :C21H26N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :402.44SX-517
CAS :<p>SX-517 is a non-competitive dual antagonist of CXCR1/2, demonstrating anti-inflammatory effects, inhibits CXCL-1-induced Ca²⁺ flux.</p>Formule :C19H16BFN2O3SCouleur et forme :SolidMasse moléculaire :382.22TN-14003
CAS :<p>TN-14003 is a synthetic antagonist 14-mer peptide inhibiting metastasis in an animal model.</p>Formule :C90H141N33O18S2Couleur et forme :SolidMasse moléculaire :2037.42RNF5 inhibitor inh-02
CAS :<p>RNF5 inhibitor inh-02 is a selective inhibitor of the ubiquitin ligase RNF5/RMA1, which can significantly rescue F508del-CFTR cystic fibrosis (CF).</p>Formule :C23H20N4SDegré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :384.5Evogliptin tartrate
CAS :<p>Evogliptin tartrate: Oral DPP-4 inhibitor, may treat atherosclerosis and diabetes.</p>Formule :C23H32F3N3O9Couleur et forme :SolidMasse moléculaire :551.51SR-17398
CAS :<p>SR-17398 is an inhibitor of Unc-51-Like Kinase 1 (ULK1) (IC50 = 22.4 uM).</p>Formule :C14H18N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :258.32(S)-Hydroxychloroquine
CAS :<p>(S)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine. Hydroxychloroquine shows efficiently inhibits SARS-CoV-2 infection in vitro.</p>Formule :C18H26ClN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :335.87IZCZ-3
CAS :<p>IZCZ-3,antitumor activity. is a potent c-MYC transcription inhibitor.</p>Formule :C46H49N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :715.93KRH-1636
CAS :<p>KRH-1636: potent, selective CXCR4 antagonist; orally active; inhibits X4 HIV-1 by blocking viral entry and membrane fusion.</p>Formule :C32H37N7O2Couleur et forme :SolidMasse moléculaire :551.68Autophagy inducer 4
CAS :<p>Autophagy inducer 4, a Magnolol-based Mannich derivative, is an anticancer agent that blocks cancer cell migration & is 76x more toxic to T47D cells.</p>Formule :C32H37NO6Couleur et forme :SolidMasse moléculaire :531.64PX20606 trans racemate
CAS :<p>PX20606 trans racemate is an agonist of FXR (EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively).</p>Formule :C29H22Cl3NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :554.85LRRK2-IN-7
CAS :<p>LRRK2-IN-7: potent, selective CNS-active LRRK2 inhibitor, IC50 0.9 nM, >1000x selectivity vs kinases/channels/CYPs.</p>Formule :C24H26N6ODegré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :414.5AZD8309
CAS :<p>AZD8309 is an oral CXCR2 antagonist, curbing neutrophil movement, lowering MPO in lungs/pancreas, and trypsin/elastase activity.</p>Formule :C15H14F2N4O2S2Degré de pureté :98.35% - 99.67%Couleur et forme :SolidMasse moléculaire :384.42ITX5061
CAS :<p>ITX5061 is a type II inhibitor of p38 MAPK and scavenger receptor B1 (SRB1) antagonist for the study of hepatitis C virus infection.</p>Formule :C30H38ClN3O7SDegré de pureté :98.35%Couleur et forme :SolidMasse moléculaire :620.16CCT020312
CAS :<p>CCT020312 (0-9 µM, 24 h) treatment of medium HT29 cells for 24 h resulted in a concentration-dependent loss of P-S608-pRB.Cost-effective and quality-assured.</p>Formule :C31H30Br2N4O2Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :650.4Atg4B-IN-2
CAS :<p>Atg4B-IN-2 is an Atg4B inhibitor with anticancer activity that inhibits Atg4B and PLA2 and resists the anticancer activity of resistant prostate cancer drugs.</p>Formule :C21H30O3Degré de pureté :98.86%Couleur et forme :SolidMasse moléculaire :330.46NUCC-390
CAS :<p>NUCC-390, a novel small-molecule CXCR4 receptor agonist, selectively induces CXCR4 receptor internalization while acting antagonistically to AMD3100.</p>Formule :C23H33N5ODegré de pureté :97.08%Couleur et forme :SolidMasse moléculaire :395.54MAPK13-IN-1
CAS :<p>MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).</p>Formule :C20H23N5O2Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :365.43
