Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
1427 produits trouvés pour "Autophagie"
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Rosiglitazone maleate
CAS :<p>Rosiglitazone maleate (BRL 49653) is an oral antidiabetic and potential anticancer agent.</p>Formule :C22H23N3O7SDegré de pureté :99.33% - 99.51%Couleur et forme :Off-White SolidMasse moléculaire :473.50Irinotecan hydrochloride trihydrate
CAS :<p>Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) keeps DNA from unwinding by inhibiting topoisomerase 1.</p>Formule :C33H45ClN4O9Degré de pureté :98.22% - >99.99%Couleur et forme :Pale Yellow To Yellow Crystalline PowderMasse moléculaire :677.18Pemetrexed
CAS :<p>Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).</p>Formule :C20H21N5O6Degré de pureté :98.1% - 99.92%Couleur et forme :Similar To White PowderMasse moléculaire :427.41Sophocarpine monohydrate
CAS :<p>Sophocarpine monohydrate, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>Formule :C15H22N2ODegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :246.35ATG7-IN-1
CAS :<p>ATG7-IN-1 is a selective ATG7 inhibitor with an IC50 of 62 nM.</p>Formule :C17H19FN6O5S2Degré de pureté :99.85% - >99.99%Couleur et forme :SolidMasse moléculaire :470.5Maprotiline hydrochloride
CAS :<p>Maprotiline hydrochloride (Psymion) is a tetracyclic antidepressant akin to tricyclics with similar side effects.</p>Formule :C20H24ClNDegré de pureté :99.68% - 99.84%Couleur et forme :White PowderMasse moléculaire :313.864Piceatannol
CAS :<p>Piceatannol (Astringenin) is a synthetic anti-inflammatory that blocks p56lck, syk kinases, and NF-κB, made from resveratrol.</p>Formule :C14H12O4Degré de pureté :98.66% - 99.73%Couleur et forme :Light Tan To Yellow PowderMasse moléculaire :244.24Olanzapine
CAS :<p>Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.</p>Formule :C17H20N4SDegré de pureté :99.86% - ≥95%Couleur et forme :Yellowish Crystalline PowderMasse moléculaire :312.43Bosutinib
CAS :<p>Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.</p>Formule :C26H29Cl2N5O3Degré de pureté :98.98% - 99.9%Couleur et forme :Yellowish-Orange Or Pink To Brownish Solid Solid PowderMasse moléculaire :530.45Hesperidin
CAS :<p>Hesperidin (Cirantin), a citrus-fruit flavanone glycoside, boasts antioxidant, anti-inflammatory, anti-carcinogenic, and cardiovascular benefits.</p>Formule :C28H34O15Degré de pureté :97.74% - 97.75%Couleur et forme :Fine Brownish Powder Solid PowderMasse moléculaire :610.56Monacolin J
CAS :<p>Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.</p>Formule :C19H28O4Degré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :320.42Xylitol
CAS :<p>Xylitol (Ribitol) is a five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group.</p>Formule :C5H12O5Degré de pureté :99.89% - 99.96%Couleur et forme :White Solid PowderMasse moléculaire :152.15Trifluoperazine dihydrochloride
CAS :Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.Formule :C21H26Cl2F3N3SDegré de pureté :99.57% - 99.96%Couleur et forme :Cream Fine PowderMasse moléculaire :480.43Fluoxetine
CAS :<p>Fluoxetine (LY-110140), a specific serotonin inhibitor, serves as an antidepressant with fewer side-effects.</p>Formule :C17H18F3NODegré de pureté :99.07% - 99.28%Couleur et forme :SolidMasse moléculaire :309.33Dexamethasone
CAS :<p>Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.</p>Formule :C22H29FO5Degré de pureté :98% - 99.91%Couleur et forme :Crystals From Ether (Ntp 1992)Masse moléculaire :392.46Salicylic acid
CAS :<p>Salicylic acid (2-Hydroxybenzoic acid), a natural compound extracted from Willow bark, is an anti-inflammatory inhibitor of activity cyclooxygenase.</p>Formule :C7H6O3Degré de pureté :98.04% - 98.83%Couleur et forme :White Solid PowderMasse moléculaire :138.12Fumagilin-105
CAS :<p>Fumagilin-105, an autophagy-targeting chimera (AUTOTAC), induces self-oligomerization of p62 and exhibits a DC50 of 0.7 μM against MetAP2 in HEK293 cells.</p>Formule :C46H60N2O9Couleur et forme :SolidMasse moléculaire :784.98SQA1
CAS :<p>SQA1 is a derivative of a phthalamide (SQA) and acts as a CCR6 antagonist with a Kd of 250 nM, as well as a CXCR2 inhibitor. It occupies an intracellular pocket that overlaps with the G protein binding site, stabilizing the pocket's closed conformation.</p>Formule :C22H26N4O5Couleur et forme :SolidMasse moléculaire :426.47TRAF6 peptide
CAS :<p>TRAF6 peptide inhibits TRAF6-p62, blocks TrkA ubiquitination, and shows promise for neurological disease research.</p>Formule :C145H238N34O44Couleur et forme :SolidMasse moléculaire :3161.64PBA-1105b
CAS :<p>PBA-1105b, a longer PEGylated derivative of PBA-1105, is an autophagy-targeting chimeric compound (AUTOTAC) that can induce self-oligomerization of p62. It enhances the autophagic flux of Ub-bound aggregates.</p>Formule :C47H64N2O10Couleur et forme :SolidMasse moléculaire :817.02
