Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
1428 produits trouvés pour "Autophagie"
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Metformin-d6 hydrochloride
CAS :<p>Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuteride of Metformin, which can be used to study Metformin metabolism in vivo.</p>Formule :C4H12ClN5Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :171.66Pyrazinamide-d3
CAS :<p>Pyrazinamide-d3 is a deuterated compound of Pyrazinamide. Pyrazinamide has a CAS number of 98-96-4. Pyrazinamide, an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide derivative.</p>Formule :C5D3H2N3OCouleur et forme :SolidMasse moléculaire :126.13Dexamethasone-d5
CAS :<p>Dexamethasone-d5 is a deuterated compound of Dexamethasone.</p>Formule :C22H24D5FO5Couleur et forme :SolidMasse moléculaire :397.49Afatinib D6
CAS :<p>Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor.</p>Formule :C24H25ClFN5O3Couleur et forme :SolidMasse moléculaire :491.98V-9302 hydrochloride
CAS :<p>V-9302 hydrochloride is a competitive transmembrane glutamine flux antagonist that selectively targets the amino acid transporter ASCT2/SLC1A5.</p>Formule :C34H39ClN2O4Degré de pureté :97.31%Couleur et forme :SolidMasse moléculaire :575.14Nilotinib-d6
CAS :<p>Nilotinib D6 is a deuterium labeled Nilotinib which is an orally available inhibitor of Bcr-Abl tyrosine kinase ,and with antineoplastic activity.</p>Formule :C28H22F3N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :535.55Megestrol Acetate-d3
CAS :<p>Megestrol Acetate-d3 is a deuterated compound of Megestrol Acetate. Megestrol Acetate has a CAS number of 595-33-5. Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometrial carcinoma and in breast cancer. Megestrol acetate has been approved to treat anorexia and cachexia.</p>Formule :C24H29D3O4Couleur et forme :SolidMasse moléculaire :387.53Silibinin-d3
<p>Silibinin-d3 is the deuterium-labelled compound of silibinin, used for isotope tracing. Silibinin inhibit cancer cell proliferation and migration.</p>Formule :C25H22O10Couleur et forme :SolidMasse moléculaire :485.46Isorhapontigenin
CAS :<p>Isorhapontigenin: a methoxylated stilbenoid isomer of rhapontigenin, similar to resveratrol, present in Gnetum spp. and Aiphanes aculeata seeds.</p>Formule :C15H14O4Degré de pureté :98.49% - 99.85%Couleur et forme :Off White Crystals PowerMasse moléculaire :258.27Valproic Acid
CAS :<p>Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.</p>Formule :C8H16O2Degré de pureté :97.78% - 99%Couleur et forme :Colourless To Pale Yellow Liquid ViscousMasse moléculaire :144.21Ginkgolide K
CAS :<p>Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity.</p>Formule :C20H22O9Degré de pureté :99.44% - 99.72%Couleur et forme :SolidMasse moléculaire :406.38Momelotinib
CAS :<p>Momelotinib (LM-1149), an oral JAK1/2 inhibitor with IC50s 11/18 nM, blocks ATP binding, disrupting JAK-STAT pathway and reducing tumor growth.</p>Formule :C23H22N6O2Degré de pureté :97.47% - 99.56%Couleur et forme :SolidMasse moléculaire :414.46Clematichinenoside AR
CAS :<p>Clematichinenoside AR is anti-inflammatory, immunosuppressive, and combats arthritis via PI3K/Akt and TNF-α pathways.</p>Formule :C82H134O43Degré de pureté :99.04% - 99.69%Couleur et forme :SolidMasse moléculaire :1807.92Tanespimycin
CAS :<p>Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!</p>Formule :C31H43N3O8Degré de pureté :99.07% - 99.83%Couleur et forme :Dark Purple SolidMasse moléculaire :585.69Selenomethionine
CAS :<p>DL-Selenomethionine (SeMet) is a selenium analog of methionine, substituting sulfur with selenium, and can replace methionine in proteins.</p>Formule :C5H11NO2SeDegré de pureté :98% - 99.95%Couleur et forme :Transparent Hexagonal Sheets Or Plates; Metallic Luster Of Crystals SolidMasse moléculaire :196.11Dimethyl fumarate
CAS :<p>Dimethyl fumarate (DMF) is an orally Nrf2 activator. Dimethyl fumarate has antimicrobial and anti-inflammatory activities. Cost-effective and quality-assured.</p>Formule :C6H8O4Degré de pureté :90.51% - >99.99%Couleur et forme :White To Off-White Powder White Crystalline PowderMasse moléculaire :144.13ABT-751
CAS :<p>ABT-751 (E7010) has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer.</p>Formule :C18H17N3O4SDegré de pureté :98.84% - 99.50%Couleur et forme :SolidMasse moléculaire :371.41GNE0877
CAS :<p>GNE0877 (GNE 0877) is a highly effective and specific leucine-rich repeat kinase 2 (LRRK2) inhibitor (Ki: 0.7 nM).</p>Formule :C14H16F3N7Degré de pureté :98.01% - 99.97%Couleur et forme :SolidMasse moléculaire :339.32Autophinib
CAS :<p>Autophinib is a potent autophagy inhibitor with a novel chemotype with IC50 values of 90 and 40 nM for autophagy in starvation induced autophagy assay and</p>Formule :C14H11ClN6O3Degré de pureté :99.25% - 99.41%Couleur et forme :SolidMasse moléculaire :346.73Corynoxine
CAS :<p>Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.</p>Formule :C22H28N2O4Degré de pureté :96.83% - 99.93%Couleur et forme :SolidMasse moléculaire :384.47
