Autophagie
Les inhibiteurs de l'autophagie ciblent le processus cellulaire de l'autophagie, qui implique la dégradation et le recyclage des composants cellulaires via les lysosomes. L'autophagie est un mécanisme crucial pour maintenir l'homéostasie cellulaire, mais sa dérégulation est impliquée dans diverses maladies, y compris le cancer, les maladies neurodégénératives et les infections. Les inhibiteurs de l'autophagie peuvent bloquer ce processus, ce qui en fait des outils précieux pour étudier le rôle de l'autophagie dans les maladies et développer des stratégies thérapeutiques. Chez CymitQuimica, nous proposons des inhibiteurs de l'autophagie pour soutenir vos recherches en biologie cellulaire, oncologie et maladies neurodégénératives.
1424 produits trouvés pour "Autophagie"
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Silmitasertib sodium salt
CAS :<p>Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).</p>Formule :C19H11ClN3NaO2Degré de pureté :99.49% - 99.62%Couleur et forme :SolidMasse moléculaire :371.75Pravastatin sodium
CAS :<p>Pravastatin sodium (CS-514 (sodium)), an HMG-CoA reductase inhibitor, inhibits sterol synthesis with IC50 of 5.6 μM.</p>Formule :C23H35NaO7Degré de pureté :97.14%Couleur et forme :White Crystalline PowderMasse moléculaire :446.52NBDHEX
CAS :<p>NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).</p>Formule :C12H15N3O4SDegré de pureté :97.38%Couleur et forme :SolidMasse moléculaire :297.33Sunitinib Malate
CAS :<p>Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.</p>Formule :C26H33FN4O7Degré de pureté :98% - 99.26%Couleur et forme :SolidMasse moléculaire :532.56Matrine
CAS :<p>Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.</p>Formule :C15H24N2ODegré de pureté :97.16% - >99.99%Couleur et forme :SolidMasse moléculaire :248.36Paclitaxel
CAS :<p>Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer.</p>Formule :C47H51NO14Degré de pureté :98% - 99.92%Couleur et forme :White PowderMasse moléculaire :853.91Crustecdysone
CAS :<p>Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.</p>Formule :C27H44O7Degré de pureté :99.06% - 99.67%Couleur et forme :Canary Yellow Fine PowderMasse moléculaire :480.63Nicardipine hydrochloride
CAS :<p>Nicardipine hydrochloride is a potent calcium channel blocker used to dilate cerebral and coronary vessels.</p>Formule :C26H30ClN3O6Degré de pureté :99.58% - 99.89%Couleur et forme :Yellow SolidMasse moléculaire :515.99BIX 02565
CAS :<p>BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM).</p>Formule :C26H30N6O2Degré de pureté :97.44% - 99.7%Couleur et forme :SolidMasse moléculaire :458.56Oxaliplatin
CAS :<p>Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis.</p>Formule :C8H14N2O4PtDegré de pureté :97% - 99.93%Couleur et forme :SolidMasse moléculaire :397.29Colistin sulfate
CAS :<p>Colistin sulfate (Colistin sulfate (1066-17-7 free base)) is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.</p>Formule :C53H100N16O17SDegré de pureté :98%Couleur et forme :PowderMasse moléculaire :1253.51Irinotecan Hydrochloride
CAS :<p>Irinotecan HCl, a camptothecin derivative prodrug, becomes active metabolite SN-38, inhibiting topoisomerase I to trigger apoptosis.</p>Formule :C33H39ClN4O6Degré de pureté :98% - 99.94%Couleur et forme :Yellow Crystalline PowderMasse moléculaire :623.14Lomustine
CAS :<p>Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.</p>Formule :C9H16ClN3O2Degré de pureté :98.36% - 99.44%Couleur et forme :Solid SolidMasse moléculaire :233.7Itraconazole
CAS :<p>Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.</p>Formule :C35H38Cl2N8O4Degré de pureté :98% - 99.90%Couleur et forme :Off-White Crystalline SolidMasse moléculaire :705.63Phenformin hydrochloride
CAS :<p>Phenformin hydrochloride (Phenformin HCl) is an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.</p>Formule :C10H16ClN5Degré de pureté :97.11% - 99.80%Couleur et forme :Lactic AcidosisMasse moléculaire :241.72Memantine hydrochloride
CAS :<p>Memantine hydrochloride (Memantine HCl) is an AMANTADINE derivative that has some dopaminergic effects.</p>Formule :C12H22ClNDegré de pureté :99.56% - 99.96%Couleur et forme :Crystalline SolidMasse moléculaire :215.76Oxidopamine hydrobromide
CAS :<p>Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.</p>Formule :C8H12BrNO3Degré de pureté :98.22% - 99.88%Couleur et forme :Beige To Brown Fine Crystalline PowderMasse moléculaire :250.09Doxorubicin hydrochloride
CAS :<p>Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).</p>Formule :C27H29NO11·HClDegré de pureté :98% - 99.52%Couleur et forme :Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Masse moléculaire :579.99Glibenclamide
CAS :<p>Glibenclamide (Glyburide) is an antidiabetic sulfonylurea derivative with actions similar to those of chlorpropamide.</p>Formule :C23H28ClN3O5SDegré de pureté :99.05% - 99.75%Couleur et forme :SolidMasse moléculaire :494.00Fluvastatin sodium
CAS :<p>Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol</p>Formule :C24H25FNNaO4Degré de pureté :98.54% - 99.56%Couleur et forme :Light Yellow Solid PowderMasse moléculaire :433.45Erlotinib
CAS :<p>Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>Formule :C22H23N3O4Degré de pureté :98.19% - 99.98%Couleur et forme :White To Off-White PowderMasse moléculaire :393.44AZD7624
CAS :<p>AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.</p>Formule :C27H30FN5O3Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :491.56Reserpine
CAS :<p>Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.</p>Formule :C33H40N2O9Degré de pureté :98.85% - 99.81%Couleur et forme :White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Masse moléculaire :608.68ZX-29
CAS :<p>ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.</p>Formule :C23H28ClN7O3SDegré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :518.03Carboplatin
CAS :<p>Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor.</p>Formule :C6H12N2O4PtDegré de pureté :98% - 99.72%Couleur et forme :White Crystalline PowderMasse moléculaire :371.25Vancomycin hydrochloride
CAS :<p>Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!</p>Formule :C66H76Cl3N9O24Degré de pureté :97.20% - 99.19%Couleur et forme :Off White PowderMasse moléculaire :1485.71Raloxifene hydrochloride
CAS :<p>Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.</p>Formule :C28H28ClNO4SDegré de pureté :98% - 99.97%Couleur et forme :Light Yellow SolidMasse moléculaire :510.044LG-100064
CAS :<p>LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)</p>Formule :C23H26O3Degré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :350.45Pyrazinamide
CAS :<p>Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide</p>Formule :C5H5N3ODegré de pureté :99.71% - 99.9%Couleur et forme :Crystals Physical Description White Powder Sublimes From 318°F (Ntp 1992)Masse moléculaire :123.11Amiodarone hydrochloride
CAS :<p>Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.</p>Formule :C25H29I2NO3·HClDegré de pureté :99.82% - ≥95%Couleur et forme :White To Cream Crystalline PowderMasse moléculaire :681.78Dexamethasone
CAS :<p>Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.</p>Formule :C22H29FO5Degré de pureté :98% - 99.91%Couleur et forme :Crystals From Ether (Ntp 1992)Masse moléculaire :392.46Avermectin B1
CAS :<p>Avermectin B1 is served as anthelmintic and insecticide.</p>Formule :C48H72O14Degré de pureté :mixture - mixtureCouleur et forme :White PowderMasse moléculaire :873.09Mevastatin
CAS :<p>Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.</p>Formule :C23H34O5Degré de pureté :99.12%Couleur et forme :White-Yellowish To Yellow Powder Solid PowderMasse moléculaire :390.51Cytarabine
CAS :<p>Cytarabine (Ara-C) is a nucleoside analog, an inhibitor of DNA synthesis (IC50=16 nM).</p>Formule :C9H13N3O5Degré de pureté :99.83% - 99.93%Couleur et forme :Fine Off-White Crystalline PowderMasse moléculaire :243.22Thalidomide
CAS :<p>Thalidomide, a glutamic acid derivative, has teratogenic and immunomodulatory effects.</p>Formule :C13H10N2O4Degré de pureté :98.88% - 99.88%Couleur et forme :White SolidMasse moléculaire :258.23Doxazosin mesylate
CAS :<p>Doxazosin mesylate (UK 33274 mesylate)(UK 33274) is a quinazoline-derivative. It is a selectively antagonizes postsynaptic α1-adrenergic receptors.</p>Formule :C24H29N5O8SDegré de pureté :99.92%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :547.58Trimetazidine dihydrochloride
CAS :<p>Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.</p>Formule :C14H24Cl2N2O3Degré de pureté :99.58%Couleur et forme :Crystalline SolidMasse moléculaire :339.258Pictilisib dimethanesulfonate
CAS :<p>Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and</p>Formule :C25H35N7O9S4Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :705.85Ketanserin
CAS :<p>Ketanserin: quinazoline derivative, 5-HT2 receptor antagonist, may lower blood pressure and inhibit blood clots.</p>Formule :C22H22FN3O3Degré de pureté :99.19% - 99.73%Couleur et forme :SolidMasse moléculaire :395.43Hydroxyurea
CAS :<p>Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.</p>Formule :CH4N2O2Degré de pureté :99.85% - 99.92%Couleur et forme :SolidMasse moléculaire :76.05MLi-2
CAS :<p>MLi-2: Novel, potent CNS-active LRRK2 inhibitor; IC50s: 0.76nM in vitro, 1.4nM cellular, 3.4nM binding.</p>Formule :C21H25N5O2Degré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :379.46Lapatinib Ditosylate
CAS :<p>Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).</p>Formule :C29H26ClFN4O4S·2C7H8O3SDegré de pureté :99.41%Couleur et forme :Yellow SolidMasse moléculaire :925.46Dihydroartemisinin
CAS :<p>Dihydroartemisinin (Artenimol) is an antimalarial drug. High-Quality, Low-Cost!</p>Formule :C15H24O5Degré de pureté :98% - 99.41%Couleur et forme :White SolidMasse moléculaire :284.35Lapatinib ditosylate monohydrate
CAS :<p>Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.</p>Formule :C29H26ClFN4O4S·2(C7H8O3S)·H2ODegré de pureté :98% - 99.41%Couleur et forme :Colourless To Light-Yellow CrystalMasse moléculaire :943.47Sophocarpine monohydrate
CAS :<p>Sophocarpine monohydrate, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>Formule :C15H22N2ODegré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :246.35Dexamethasone acetate
CAS :<p>Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.</p>Formule :C24H31FO6Degré de pureté :99.22% - 99.65%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :434.50Spironolactone
CAS :<p>Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.</p>Formule :C24H32O4SDegré de pureté :99.87%Couleur et forme :White PowderMasse moléculaire :416.57Chenodeoxycholic acid
CAS :<p>Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!</p>Formule :C24H40O4Degré de pureté :99.70% - 99.93%Couleur et forme :White - Almost White Solid PowderMasse moléculaire :392.57TTNPB
CAS :<p>TTNPB (Ro 13-7410,AGN-191183), a potent RAR agonist, inhibits binding of [3H]tRA of human RARα (IC50: 5.1 nM), β (IC50: 4.5 nM), and γ (IC50: 9.3 nM),</p>Formule :C24H28O2Degré de pureté :99.55%Couleur et forme :White SolidMasse moléculaire :348.48Naringin
CAS :<p>Naringin: flavanone glycoside with blood lipid-reducing, antioxidant, anticancer properties, inhibits cytochrome P450.</p>Formule :C27H32O14Degré de pureté :99.23%Couleur et forme :Beige Creamish Powder Solid Solid Particulate/PowderMasse moléculaire :580.53
