Récepteur cannabinoïde
Les récepteurs cannabinoïdes sont des GPCR qui médiatisent les effets des cannabinoïdes endogènes (endocannabinoïdes) et des phytocannabinoïdes, tels que ceux trouvés dans le cannabis. Les deux principaux types de récepteurs cannabinoïdes, CB1 et CB2, sont impliqués dans la régulation d'une large gamme de processus physiologiques, y compris la perception de la douleur, l'appétit, l'humeur et la fonction immunitaire. Les modulateurs des récepteurs cannabinoïdes ont un potentiel thérapeutique dans le traitement de conditions telles que la douleur chronique, l'épilepsie et la sclérose en plaques. Chez CymitQuimica, nous offrons une large gamme de modulateurs de récepteurs cannabinoïdes de haute qualité pour soutenir vos recherches en neuropharmacologie, gestion de la douleur et immunologie.
217 produits trouvés pour "Récepteur cannabinoïde"
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JHU 75528
CAS :JHU 75528 (JHU-75528) is a novel PET tracer with inhibitory effects on CB that can be used to study the cannabinoid system in schizophrenic patients.Formule :C23H21Cl2N5O2Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :470.35CB1 antagonist 2
CAS :CB1 antagonist 2 (AM4113) is caimabinoid 1 (CB1) antagonist which inhibits CB1 in vivo with an IC50 of 25.5 nM.Formule :C17H12Cl3N3ODegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :380.66Rimonabant
CAS :Rimonabant (SR141716) is an inverse agonist for the cannabinoid receptor CB1.Formule :C22H21Cl3N4ODegré de pureté :98% - 99.91%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :463.79Rimonabant hydrochloride
CAS :Rimonabant hydrochloride (SR 141716A) 是中心大麻素受体 1 的高效选择性反向激动剂， Ki 值为1.8 nM。它也能够抑制分枝杆菌膜蛋白3。Formule :C22H22Cl4N4ODegré de pureté :98.24% - 99.5%Couleur et forme :Off-White To White Crystalline PowderMasse moléculaire :500.256-Iodopravadoline
CAS :6-Iodopravadoline (AM630) is an antagonist of CB2 (Ki: 31.2 nM). And it shows 165-fold selectivity more than CB1 receptors.Formule :C23H25IN2O3Degré de pureté :99.29%Couleur et forme :Off-White SolidMasse moléculaire :504.36Ref: TM-T14204
1mg38,00€2mg52,00€5mg70,00€10mg90,00€25mg198,00€50mg326,00€100mg520,00€1mL*10mM (DMSO)99,00€EHP-101
CAS :EHP-101 is a PPARγ/CB2 dual agonist with anti-inflammatory properties, inhibits fat formation, and combats diet-related obesity.Formule :C28H35NO3Degré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :433.58Ref: TM-T13289
1mg107,00€5mg227,00€10mg378,00€25mg620,00€50mg868,00€100mg1.169,00€1mL*10mM (DMSO)250,00€Pregnenolone
CAS :Pregnenolone (Arthenolone) is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.Formule :C21H32O2Degré de pureté :99.5% - 99.84%Couleur et forme :SolidMasse moléculaire :316.48Anandamide
CAS :Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but alsoFormule :C22H37NO2Degré de pureté :95.037% - 99.22%Couleur et forme :Light Yellow OilMasse moléculaire :347.53Ref: TM-T14046
1mg34,00€2mg46,00€5mg67,00€10mg117,00€25mg221,00€50mg330,00€100mg485,00€200mg675,00€1mL*10mM (DMSO)73,00€CB2 receptor agonist 9
CAS :CB2 receptor agonist 9 (Compound 33) is an orally active agonist of cannabinoid receptor 2 (CB2 receptor) with an EC50 of 16.2 nM. It inhibits the expression of TNF-α, IL-1β, and IL-6, demonstrating anti-inflammatory activity in a DSS-induced acute colitis model in mice.Formule :C16H23N3O2SCouleur et forme :SolidMasse moléculaire :321.44Afubiata
CAS :ADB-FUBIATA is a synthetic cannabinoid studied for its metabolic profile, along with AFUBIATA, CH-FUBIATA, and CH-PIATA. This in vitro analysis by Watanabe S, et al., examines these compounds, as published in "Arch Toxicol," 2023 Dec;97(12):3085-3094.Formule :C27H29FN2OCouleur et forme :SolidMasse moléculaire :416.53(±)-9-Nor-9α-hydroxy Hexahydrocannabinol
CAS :(±)-9-Nor-9α-hydroxy Hexahydrocannabinol is a cannabinoid-structured compound that exhibits potent cannabinoid-like activity in both dogs and mice.Formule :C20H30O3Couleur et forme :SolidMasse moléculaire :318.45exo-Tetrahydrocannabivarin
CAS :exo-Tetrahydrocannabivarin (Compound 12) is an analog of Δ9,11-THC. It weakly binds to cannabinoid receptors (CB) with an IC50 of 1.4 μM. In mice, exo-Tetrahydrocannabivarin exhibits activity related to both motor function and analgesia.Formule :C19H26O2Couleur et forme :SolidMasse moléculaire :286.41Cannabigerorcin
CAS :Cannabigerorcin, a phytocannabinoid, serves as an analytical reference standard. It is designated for research and forensic applications.Formule :C17H24O2Couleur et forme :SolidMasse moléculaire :260.3778β-Hydroxy-exo-THC
CAS :8β-Hydroxy-exo-THC, a cannabinoid ether analog, exhibits weak affinity for receptor sites with an IC50 of 1.2 μM.Formule :C21H30O3Couleur et forme :SolidMasse moléculaire :330.46Δ8-THC methyl ether
CAS :Δ8-THC methyl ether (compound 3) demonstrates a strong docking score of -10.167 kcal/mol for the CB2 receptor. Additionally, Δ8-THC methyl ether exhibits antinociceptive activity in mice.Formule :C22H32O2Couleur et forme :SolidMasse moléculaire :328.49CB2R/FAAH modulator-3
CAS :CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH.Formule :C22H31NO2Degré de pureté :99.81%Couleur et forme :SoildMasse moléculaire :341.49CB2R/FAAH modulator-1
CAS :CB2R/FAAH modulator-1: agonizes CB2R, inhibits FAAH (IC50=4 μM), alters cytokine production; used in inflammation research. Ki: CB2R=14.8 nM, CB1R=241.3 nM.Formule :C24H27NO2Degré de pureté :99.77%Couleur et forme :SoildMasse moléculaire :361.48Ref: TM-T67896
1mg50,00€5mg105,00€10mg154,00€25mg224,00€50mg314,00€100mg427,00€200mg575,00€1mL*10mM (DMSO)108,00€Δ8-THC-C8
CAS :Δ8-THC-C8 is a semi-synthetic cannabinoid. It acts as an agonist for the cannabinoid receptor 1 (CB1) with an EC50 value of 13.8 nM.Formule :C24H36O2Couleur et forme :SolidMasse moléculaire :356.54δ8-THC acetate
CAS :Delta8-THC acetate (Delta8-tetrahydrocannabinol) is a psychoactive cannabinoid that binds to the cannabinoid receptor 1 (CB1 receptor) and exhibits anti-nausea, appetite-stimulating, and anti-inflammatory effects. It may also offer neuroprotective benefits and has potential applications in research on anxiety and depression.Formule :C23H32O3Couleur et forme :SolidMasse moléculaire :356.5Drinabant
CAS :Drinabant (AVE-1625) is an orally active CB1 receptor antagonist.Formule :C23H20Cl2F2N2O2SDegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :497.38TRPV1/CB2 agonist 1
TRPV1/CB2 agonist 1 (compound 41) is a dual agonist targeting hTRPV1 and CB2 receptors, with an EC50 value of 26.8 μM for hTRPV1. It is applicable in research related to the nervous system.Couleur et forme :Odour SolidCB2R/FAAH modulator-2
CAS :CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH.Formule :C24H33NO2Degré de pureté :99.15%Couleur et forme :SoildMasse moléculaire :367.52Cannabigerorcinic Acid
CAS :Cannabigerorcinic acid, structurally akin to recognized phytocannabinoids, serves as an analytical reference standard designed for research and forensic purposes.Formule :C18H24O4Couleur et forme :SolidMasse moléculaire :304.386APP-FUBINACA
CAS :APP-FUBINACA is a cannabinoid receptor agonist, classified as a phenylalanine amide-based indazole-3-carboxamide derivative. It exhibits neurostimulatory effects.Formule :C24H21FN4O2Couleur et forme :SolidMasse moléculaire :416.45(−)-6α-hydroxy Cannabidiol
CAS :(−)-6α-Hydroxy Cannabidiol, an analytical reference standard and a phytocannabinoid metabolite, serves primarily as a metabolite of cannabidiol (CBD). This product is designed for use in research and forensic applications.Formule :C21H30O3Couleur et forme :SolidMasse moléculaire :330.46CB2R probe 1
CAS :CB2R Probe 1, a cannabinoid 2 receptor (CB2R) fluorescent probe, exhibits both safety and environmental friendliness, boasting a dissociation constant (K i) of
Formule :C36H42N4O4Couleur et forme :SolidMasse moléculaire :594.74CB2 receptor antagonist 2
Compound 39, also known as CB2 receptor antagonist 2, is a potent CB2 antagonist exhibiting an IC50 of 0.33 μM.Couleur et forme :Odour SolidHemopressin (human, mouse)
CAS :Endogenous peptide, inhibits ep24.15/24.16/ACE with Ki of 27.76/3.43/1.87 μM. Lowers blood pressure, CB1 inverse agonist, reduces pain in vivo.Formule :C50H79N13O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1054.26CB1-IN-3
CB1-IN-3 (Compound 6i) is a potent inhibitor of the cannabinoid receptor type 1 (CB1). It holds potential for research in obesity, inflammation, and neurological disorders.Couleur et forme :Odour Solid(R)-Zevaquenabant
(R)-Zevaquenabant ((R)-MRI-1867) is the enantiomer of Zevaquenabant. Zevaquenabant ((S)-MRI-1867) is a peripherally restricted, orally bioavailable dual antagonist of the cannabinoid CB1 receptor and inducible nitric oxide synthase (iNOS). It is beneficial in improving chronic kidney disease (CKD) caused by obesity.Couleur et forme :Odour SolidN-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide
CAS :N-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide: binds CB1 (Ki=365 nM), activates PPARα (EC50=698 nM), reduces rat food intake, no FAAH inhibition.Formule :C27H45NO3Couleur et forme :SolidMasse moléculaire :431.661Noladin ether
CAS :Noladin ether (2-AG ether) is a cannabinoid CB1 receptor agonist.Formule :C23H40O3Couleur et forme :SolidMasse moléculaire :364.56Calcitonin-13C6,15N4 TFA
Calcitonin-13CIC6,15NIC4(salmon) (Salmon calcitonin-13CIC6,15NIC4) TFA is a version of calcitonin(salmon) labeled with carbon-13 and nitrogen-15. This hormone regulates calcium and acts dualistically as an agonist to both amylin and calcitonin receptors, promoting bone formation while inhibiting bone resorption.Formule :C1401C5H240N4315NO48S2·5C2HF3O2Couleur et forme :SolidMasse moléculaire :4007.93Zevaquenabant
CAS :Zevaquenabant (S-MRI-1867): oral CB1/iNOS antagonist combatting obesity-induced CKD.Formule :C25H21ClF3N5O2SCouleur et forme :SolidMasse moléculaire :547.98GFB-024
GFB-024 is a humanized antibody targeting CB1, which can be used to study obesity.Couleur et forme :LiquidMasse moléculaire :146.12 kDaGPR55 agonist 4
GPR55 agonist 4 (Compound 28), with an EC50 of 131 nM for hGPR55 and 1.41 nM for rGPR55, effectively induces β-arrestin recruitment to human GPR55 [1].Formule :C19H16FN5O2Couleur et forme :SolidMasse moléculaire :365.36Hemopressin(rat)
CAS :Peptide inhibitor for ep24.15, neurolysin & ACE with Ki 27.76, 3.43, 1.87 μM. Lowers blood pressure, modulates CB1 receptor, reduces pain & food intake.Formule :C53H77N13O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1088.27Vicasinabin
CAS :Vicasinabin: potent CB2 agonist; researches chronic pain, atherosclerosis, bone mass, neuroinflammation.Formule :C15H22N10OCouleur et forme :SolidMasse moléculaire :358.41RVD-Hpα
CAS :N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist.Formule :C65H105N19O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1424.66NESS 0327
CAS :NESS 0327 is a high selectivity antagonist of the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor.Formule :C24H23Cl3N4ODegré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :489.82Tocrifluor T1117
CAS :Fluorescent form of AM 251, CB1 receptor antagonistFormule :C56H53Cl2N7O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :974.97Hemopressin(human, mouse) TFA
CAS :Hemopressin TFA: nonapeptide from hemoglobin, oral CB1 inverse agonist, eases inflammatory pain.Formule :C52H80F3N13O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1168.27CB2 receptor agonist 2
CAS :CB2 receptor agonist 2 (ZINC72105556): potent, Ki=8.5 nM, high selectivity for CB2.
Formule :C30H36N2O4Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :488.62CB1R agonist 1
CB1R agonist 1 (Compound '1350) is a potent full agonist of the cannabinoid-1 receptor (CB1R) with a Ki value of 0.95 nM. It demonstrates significant pain-relieving effects in various pain models, including acute thermal pain, inflammatory pain, and neuropathic pain.Formule :C20H18F3N3O3SCouleur et forme :SolidMasse moléculaire :437.435Cannabidivarinic acid
CAS :Cannabidivarinic acid (CBDVA), the carboxylic acid precursor to cannabidivarin (CBDV), is a non-psychoactive cannabinoid found in Cannabis and known for its anti-inflammatory properties.Formule :C20H26O4Couleur et forme :SolidMasse moléculaire :330.42VIP36
VIP36 is an agonist of the cannabinoid type 1 receptor (CB1) with analgesic properties. It reduces the recruitment of inhibitory proteins, thereby exerting its pain-relieving effects, and is applicable in research related to chronic pain.Formule :C27H35FN6O4Couleur et forme :SolidMasse moléculaire :526.603Cannabinol methyl ether
CAS :Cannabinol methyl ether, a phytocannabinoid, serves as an analytical reference standard. This compound can be obtained through isolation from Cannabis plants, derived from cannabinol, or synthesized. The physiological and toxicological properties of cannabinol methyl ether remain unknown. It is designed exclusively for research and forensic applications.Formule :C22H28O2Couleur et forme :SolidMasse moléculaire :324.5Δ9-THCH
CAS :Δ9-THCH, a phytocannabinoid analytical reference standard, is present in a Cannabis variety cultivated for medicinal use. In the United States, it is classified as a Schedule I compound. This product is designated for research and forensic applications.Formule :C22H32O2Couleur et forme :SolidMasse moléculaire :328.49CB1R antagonist 2
CB1R antagonist 2 (Compound 11g) functions as an antagonist of the cannabinoid receptor 1 (CB1R), inhibiting the MAPK/NF-κB signaling pathway and exhibiting anti-inflammatory properties. In RAW264.7 cells, it suppresses LPS-induced expression of IL-6, IL-1β, and TNF-α. In murine models, it improves OVA-induced allergic rhinitis.Formule :C24H26N4OCouleur et forme :SolidMasse moléculaire :386.49PSB-SB-1203
CAS :PSB-SB-1203 (Compound 25b) is a dual CB1/CB2 ligand that blocks the CB1 receptor and activates the CB2 receptor with a CB1 Ki of 0.244 μM, a CB2 Ki of 0.210 μM, and an EC50 of 0.054 μM. It shows potential for research in obesity and cancer.Formule :C25H30O4Couleur et forme :SolidMasse moléculaire :394.5
