DHFR
La dihydrofolate réductase (DHFR) est une enzyme qui joue un rôle crucial dans le cycle des folates, essentiel pour la synthèse, la réparation et la méthylation de l'ADN. Les inhibiteurs de la DHFR sont largement utilisés comme agents chimiothérapeutiques dans le traitement du cancer et des maladies auto-immunes en raison de leur capacité à inhiber la prolifération cellulaire. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de la DHFR pour soutenir vos recherches en thérapie anticancéreuse, immunologie et biologie moléculaire.
32 produits trouvés pour "DHFR"
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P 218
CAS :<p>P 218 is a novel DHFR inhibitor with antimalarial activity and antifolate effects and can be used to study Buruli ulcer.</p>Formule :C18H25ClN4O4Degré de pureté :98.83%Couleur et forme :SoildMasse moléculaire :396.87Diaveridine
CAS :<p>Diaveridine (AI3-23935) (DVD) is a popular antibacterial synergist that is widely used in combination with sulfonamide.</p>Formule :C13H16N4O2Degré de pureté :99.10%Couleur et forme :White SolidMasse moléculaire :260.29Pemetrexed
CAS :<p>Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).</p>Formule :C20H21N5O6Degré de pureté :98.1% - 99.92%Couleur et forme :Similar To White PowderMasse moléculaire :427.41Pyrimethamine
CAS :<p>Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.</p>Formule :C12H13ClN4Degré de pureté :99.67%Couleur et forme :CrystalsMasse moléculaire :248.71Sulfameter
CAS :<p>Sulfameter (Sulfametoxydiazine) is a long-acting sulfonamide antibacterial agent used to treat urinary tract infections and leprosy.</p>Formule :C11H12N4O3SDegré de pureté :99.46% - 99.90%Couleur et forme :Crystalline SolidMasse moléculaire :280.3DHFR-IN-21
<p>DHFR-IN-21 (compound 5p) is an inhibitor of dihydrofolate reductase.</p>Couleur et forme :Odour SolidEGFR/HER2/DHFR-IN-2
<p>EGFR/HER2/DHFR-IN-2 (Compound 4b) serves as an inhibitor for EGFR, HER2, and DHFR, with IC50 values of 0.248, 0.156, and 0.138 μM, respectively.</p>Degré de pureté :98%Couleur et forme :Odour SolidDHFR-IN-11
<p>DHFR-IN-11 (compound 6b) is a DHFR inhibitor with demonstrated inhibitory efficacy against the M.</p>Couleur et forme :Odour SolidDHFR-IN-20
<p>DHFR-IN-20 (Compound LA1) is an inhibitor of dihydrofolate reductase (DHFR) targeting the malignant strains of the malaria parasite. It exhibits inhibition constants (Kis) of 0.16 nM, 0.30 nM, and 6.6 nM for PfDHFR-WT, PfDHFR-QM, and HsDHFR, respectively. Additionally, DHFR-IN-20 demonstrates antimalarial activity, with IC50 values of 1.4 nM against parasites carrying the wild-type (TM4/8.2) PfDHFR enzyme and 1.6 μM against those with the quadruple mutation (V1/S)PfDHFR.</p>Couleur et forme :Odour SolidDHFR-IN-16
<p>DHFR-IN-16 (compound 8d) is an inhibitor of dihydrofolate reductase (DHFR) with an IC50 of 0.199 μM, and is valuable for anti-infection research.</p>Formule :C32H34N4O4SMasse moléculaire :570.23008DHFR-IN-18
<p>DHFR-IN-18 (compound 19D) is a DHFR inhibitor utilized in leukemia-related research.</p>Formule :C24H22ClN7Masse moléculaire :443.16252EGFR/DHFR-IN-1
<p>EGFR/DHFR-IN-1 (Compound 10e) is a dual inhibitor of EGFR and DHFR, with IC50 values of 0.151 µM and 0.541 µM, respectively. It induces cell cycle arrest in the G0-G1 and S phases.</p>Formule :C24H26N4O5S2Masse moléculaire :514.13446Anti-Dihydrofolate reductase Antibody (2V859)
<p>Anti-Dihydrofolate reductase Antibody (2V859) is an antibody targeting Dihydrofolate reductase. Anti-Dihydrofolate reductase Antibody (2V859) can be used in ELISA, WB, IHC, IP.</p>Couleur et forme :Odour LiquidFanotaprim
CAS :<p>Fanotaprim is a dihydrofolate reductase (DHFR) inhibitor.</p>Formule :C19H22N8ODegré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :378.43WR99210 hydrochloride(47326-86-3 free base)
CAS :<p>WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target.</p>Formule :C14H19Cl4N5O2Degré de pureté :97.77% - 99.8%Couleur et forme :SolidMasse moléculaire :431.14WR99210
CAS :<p>WR99210 (BRL 6231 free base) is a DHFR inhibitor with antiparasitic activity.</p>Formule :C14H18Cl3N5O2Degré de pureté :98.8%Couleur et forme :SolidMasse moléculaire :394.68DHFR-IN-3
CAS :<p>DHFR-IN-3 (7-bromoquinazoline-2,4-diamine) is an active biochemical.</p>Formule :C8H7BrN4Degré de pureté :99.521% - 99.65%Couleur et forme :SolidMasse moléculaire :239.07Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)
<p>Key enzyme in folate metabolism.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :25.6 kDa (predicted)Dihydrofolate reductase Protein, Human, Recombinant (His)
<p>Key enzyme in folate metabolism.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :25.5 kDa (predicted)Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His)
<p>Key enzyme in folate metabolism.</p>Couleur et forme :Lyophilized PowderMasse moléculaire :22.0 kDa (predicted)
