Synthèse ADN/ARN
Les inhibiteurs de la synthèse de l'ADN et de l'ARN sont des composés qui interfèrent avec les processus de réplication et de transcription dans les cellules, empêchant ainsi la production de matériel génétique essentiel. Ces inhibiteurs peuvent cibler diverses enzymes et protéines impliquées dans la synthèse des acides nucléiques, ce qui en fait des outils précieux pour étudier les mécanismes de réplication, de transcription et de traduction. Ils sont également utilisés dans le développement de traitements contre les infections et le cancer. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de la synthèse de l'ADN/ARN pour soutenir vos recherches en biologie moléculaire, virologie et développement thérapeutique.
708 produits trouvés pour "Synthèse ADN/ARN"
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L67
CAS :<p>L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).</p>Formule :C16H14Br2N4O4Degré de pureté :98.34% - 99.56%Couleur et forme :SolidMasse moléculaire :486.11Pseudouridine
CAS :<p>Pseudouridine, prevalent in non-coding RNAs, boosts tRNA and rRNA function by RNA stabilization.</p>Formule :C9H12N2O6Degré de pureté :99.3%Couleur et forme :SolidMasse moléculaire :244.2Garenoxacin mesylate hydrate
CAS :<p>Garenoxacin mesylate hydrate (Garenoxacin mesylate [USAN]) with potent antimicrobial activity, against common respiratory pathogens, including resistant strains</p>Formule :C23H20F2N2O4·CH4O3S·H2ODegré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :540.53NSC 617145
CAS :<p>NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent</p>Formule :C13H10Cl4N2O4Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :400.04Gemcitabine hydrochloride
CAS :<p>Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.</p>Formule :C9H11F2N3O4·HClDegré de pureté :99.28% - 99.98%Couleur et forme :White Crystalline Granular OdorlessMasse moléculaire :299.66Isoindigotin
CAS :<p>Isoindigotin is used in the therapy of Y.</p>Formule :C16H10N2O2Degré de pureté :98.14% - ≥95%Couleur et forme :SolidMasse moléculaire :262.26Pyridostatin Trihydrochloride
CAS :<p>Pyridostatin Trihydrochloride (RR-82 Trihydrochloride) is a G-quadruplexe stabilizer, with a Kd of 490 nM.</p>Formule :C31H35Cl3N8O5Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :706.02Quinizarin
CAS :<p>Quinizarin (1,4-Dihydroxyanthraquinone) is a natural product</p>Formule :C14H8O4Degré de pureté :95.02%Couleur et forme :Leaves Yellow Red And Needles Dark Red Solid Leaves Or NeedlesMasse moléculaire :240.21O6-Benzylguanine
CAS :<p>O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.</p>Formule :C12H11N5ODegré de pureté :98.9%Couleur et forme :Solid CrystallineMasse moléculaire :241.25Deoxycytidine triphosphate
CAS :<p>dCTP is a nucleotide used in DNA synthesis, PCR, cDNA creation, and sequencing.</p>Formule :C9H16N3O13P3Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :467.16GS-441524
CAS :<p>GS-441524 treatment of cats with naturally occurring feline infectious peritonitis.</p>Formule :C12H13N5O4Degré de pureté :98.78% - 99.75%Couleur et forme :SolidMasse moléculaire :291.26Methotrexate disodium
CAS :<p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>Formule :C20H20N8Na2O5Degré de pureté :99.77% - 99.96%Couleur et forme :SolidMasse moléculaire :498.4Pyridostatin TFA
CAS :<p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>Formule :C37H35F9N8O11Degré de pureté :97.09% - 99.84%Couleur et forme :SolidMasse moléculaire :938.71L189
CAS :<p>L189 is a human DNA ligase inhibitor, inhibits hLigI/III/IV (IC50: 5/9/5 μM).</p>Formule :C11H10N4OSDegré de pureté :97.37%Couleur et forme :SolidMasse moléculaire :246.29TH588
CAS :<p>TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.</p>Formule :C13H12Cl2N4Degré de pureté :96.05% - 99.82%Couleur et forme :SolidMasse moléculaire :295.17PfDHODH-IN-1
CAS :<p>PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis.</p>Formule :C14H11F3N2O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :296.24NSAH
CAS :<p>NSAH (2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide) is a nonnucleoside inhibitor of human ribonucleotide reductase (hRR).with cell-</p>Formule :C18H14N2O3Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :306.32Triciribine
CAS :Triciribine (NSC-154020) is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2.Formule :C13H16N6O4Degré de pureté :99.01% - 99.87%Couleur et forme :SolidMasse moléculaire :320.3Levofloxacin hydrochloride
CAS :<p>Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>Formule :C18H21ClFN3O4Degré de pureté :99.78% - 99.98%Couleur et forme :SolidMasse moléculaire :397.8CeMMEC13
CAS :<p>CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).</p>Formule :C19H16N2O4Degré de pureté :98.52%Couleur et forme :SolidMasse moléculaire :336.34SCR130
CAS :<p>SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。</p>Formule :C19H13Cl2N3O2SDegré de pureté :98.9%Couleur et forme :SolidMasse moléculaire :418.3360A
CAS :<p>360A is a stabilizing G-Quadruplex ligand, and also inhibits telomerase activity for telomerase in TRAP-G4 assay(IC50 : 300 nM).</p>Formule :C27H23N5O2Degré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :449.5PCNA-I1
CAS :<p>PCNA-I1 is an inhibitor targeting PCNA chromatin association in prostate cancer.</p>Formule :C17H14N2O2SDegré de pureté :97.64%Couleur et forme :SolidMasse moléculaire :310.376-AZATHYMINE
CAS :<p>6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.</p>Formule :C4H5N3O2Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :127.1RI-2
CAS :<p>RI-2, a potent RAD51 inhibitor, has a 44.17 μM IC50 and selectively blocks human HR repair.</p>Formule :C21H18Cl2N2O4Degré de pureté :99.63% - 99.86%Couleur et forme :SolidMasse moléculaire :433.28AT-130
CAS :<p>AT-130: Strong HBV inhibitor (IC50 0.13 μM), low toxicity in HepAD38, hinders RNA packaging.</p>Formule :C22H22BrN3O5Degré de pureté :97.81%Couleur et forme :SolidMasse moléculaire :488.33CRT0044876
CAS :<p>CRT0044876 (7-NO2-ICA) is a potent and selective APE1 inhibitor with IC50 of ~3 μM.</p>Formule :C9H6N2O4Degré de pureté :98.27% - 98.98%Couleur et forme :Brown PowderMasse moléculaire :206.15Ro5-3335
CAS :<p>Ro5-3335 (CBFβ-Runx1 inhibitor II) is core binding factor (CBF) inhibitor; preferentially kills human leukemia cell lines with CBF fusion proteins.</p>Formule :C13H10ClN3ODegré de pureté :99.42% - 99.87%Couleur et forme :SolidMasse moléculaire :259.69Favipiravir
CAS :<p>Favipiravir is a potent and selective RNA-dependent RNA polymerase inhibitor for the treatment of influenza virus infections.Cost-effective and quality-assured.</p>Formule :C5H4FN3O2Degré de pureté :97.32% - 99.90%Couleur et forme :SolidMasse moléculaire :157.1Quarfloxin
CAS :<p>Quarfloxin (CX-3543), a fluoroquinolone, inhibits neuroblastoma with nanomolar IC50, disrupting nucleolin and G-quadruplex DNA.</p>Formule :C35H33FN6O3Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :604.67Madrasin
CAS :<p>Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.</p>Formule :C16H17N5O2Degré de pureté :99.06% - 99.61%Couleur et forme :SolidMasse moléculaire :311.34Nimustine Hydrochloride
CAS :<p>Nimustine Hydrochloride (Nidran hydrochloride) has been used in trials studying the treatment of Glioblastoma.</p>Formule :C9H14Cl2N6O2Degré de pureté :98.80%Couleur et forme :SolidMasse moléculaire :309.15Cidofovir
CAS :<p>Cidofovir ((S)-HPMPC) 通过特异性抑制病毒 DNA 合成来抑制病毒复制。</p>Formule :C8H14N3O6PDegré de pureté :99.24% - 99.76%Couleur et forme :Fluffy White PowderMasse moléculaire :279.19RAD51-IN-1
CAS :<p>Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.</p>Formule :C22H16ClN3ODegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :373.833-Hydroxy-2-methylpyridine
CAS :<p>3-Hydroxy-2-methylpyridine could as a promising molecular scaffold for the future development of novel fibrillization inhibitors.</p>Formule :C6H7NODegré de pureté :98.96% - 99.03%Couleur et forme :Beige-Brown PowderMasse moléculaire :109.13NITD-2
CAS :<p>NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.</p>Formule :C23H19N3O4SDegré de pureté :98.03% - 99.46%Couleur et forme :SolidMasse moléculaire :433.48CBFβ Inhibitor
CAS :<p>CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.</p>Formule :C12H14N2OSDegré de pureté :96.50%Couleur et forme :SolidMasse moléculaire :234.32CX-5461
CAS :<p>CX5461 is an orally rRNA synthesis inhibitor that inhibits Pol I-driven rRNA transcription. CX5461 has antitumor activity. Cost-effective and quality-assured.</p>Formule :C27H27N7O2SDegré de pureté :95.44% - 99.25%Couleur et forme :SolidMasse moléculaire :513.61BVDV-IN-1
CAS :<p>BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM.</p>Formule :C20H22N4ODegré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :334.41Danofloxacin
CAS :<p>Danofloxacin (Danofloxacin free base) is a fluoroquinolone antibiotic used in veterinary medicine.</p>Formule :C19H20FN3O3Degré de pureté :99.77% - 99.8%Couleur et forme :SolidMasse moléculaire :357.38Cynaroside
CAS :<p>Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.</p>Formule :C21H20O11Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :448.38Levofloxacin
CAS :<p>Levofloxacin ((-)-Ofloxacin) is a synthetic fluoroquinolone antibiotic that prevents DNA replication. Cost-effective and quality-assured.</p>Formule :C18H20FN3O4Degré de pureté :98.14% - 99.80%Couleur et forme :Off-White To Yellow CrystalsMasse moléculaire :361.37Zoliflodacin
CAS :<p>Zoliflodacin (ETX0914) (ETX0914, AZD0914) is a new bacterial DNA gyrase/topoisomerase inhibitor.</p>Formule :C22H22FN5O7Degré de pureté :99.82% - 99.93%Couleur et forme :SolidMasse moléculaire :487.44Tubercidin
CAS :<p>Tubercidin, an adenosine analogue nucleoside antibiotic, hinders DNA/RNA synthesis and possesses antifungal and antiviral properties.</p>Formule :C11H14N4O4Degré de pureté :98.66% - >99.99%Couleur et forme :SolidMasse moléculaire :266.25Branaplam
CAS :<p>Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.</p>Formule :C22H27N5O2Degré de pureté :98.28% - 99.72%Couleur et forme :SolidMasse moléculaire :393.485-Methylcytosine
CAS :<p>5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA.</p>Formule :C5H7N3ODegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :125.13N-Nitrosodiethylamine
CAS :<p>N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine.</p>Formule :C4H10N2ODegré de pureté :99.26% - 99.88%Couleur et forme :SolidMasse moléculaire :102.14Bractoppin
CAS :<p>Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits</p>Formule :C25H23FN4ODegré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :414.47ML264
CAS :<p>ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.</p>Formule :C17H21ClN2O4SDegré de pureté :99.33% - 99.45%Couleur et forme :SolidMasse moléculaire :384.88Didox
CAS :<p>Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.</p>Formule :C7H7NO4Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :169.13(S)-crizotinib
CAS :<p>(S)-crizotinib (ent-crizotinib) （IC50 of 72 nM）, an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.</p>Formule :C21H22Cl2FN5ODegré de pureté :98.52% - 99.47%Couleur et forme :SolidMasse moléculaire :450.34COH29
CAS :<p>COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.</p>Formule :C22H16N2O5SDegré de pureté :97.04% - 98.92%Couleur et forme :SolidMasse moléculaire :420.44Tempo
CAS :<p>Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a</p>Formule :C9H18NODegré de pureté :98.35%Couleur et forme :Orange Crystals Or PowderMasse moléculaire :156.25Fialuridine
CAS :<p>Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.</p>Formule :C9H10FIN2O5Degré de pureté :99.71% - 99.88%Couleur et forme :Less Crystals Colourless CrystalsMasse moléculaire :372.09TH287 hydrochloride
CAS :<p>TH287 inhibits MTH1 (IC50: 0.8 nM), causing DNA damage in cancer cells through oxidized dNTP incorporation, leading to cytotoxicity in mouse xenografts.</p>Formule :C11H11Cl3N4Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :305.59Neobavaisoflavone
CAS :<p>Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.</p>Formule :C20H18O4Degré de pureté :99.31% - 99.87%Couleur et forme :SolidMasse moléculaire :322.352'-O-(2-Methoxyethyl)adenosine
CAS :<p>2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.</p>Formule :C13H19N5O5Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :325.32PolQi2
CAS :<p>PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.</p>Formule :C21H16ClN5O3SDegré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :453.95-Bromouridine
CAS :<p>5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.</p>Formule :C9H11BrN2O6Degré de pureté :99.89%Couleur et forme :White PowderMasse moléculaire :323.1DHX9-IN-8
CAS :<p>DHX9-IN-8 (Compound 6) functions as an inhibitor of the RNA helicase DHX9, exhibiting an EC50 of 3.4 μM for cellular target engagement within DHX9. It is primarily utilized in cancer research [1].</p>Formule :C18H16N2O3S2Couleur et forme :SolidMasse moléculaire :372.46Metribuzin
CAS :<p>Metribuzin is a selective herbicide used on crops like soybeans and potatoes. It inhibits photosynthesis and is a persistent groundwater contaminant.</p>Formule :C8H14N4OSDegré de pureté :99.07%Couleur et forme :Colorless Crytals Metribuzin Is A Colorless Crystalline Solid Used As An Herbicide (Niosh 2016)Masse moléculaire :214.29VVD-214
CAS :<p>VVD-214 (RO7589831) is a WRN deconjugation enzyme lethal-mutagenic inhibitor that can be used to study proliferative diseases.</p>Formule :C20H21F2N3O4SDegré de pureté :99.24%Couleur et forme :SoildMasse moléculaire :437.46Locked nucleic acid 1
CAS :<p>Locked nucleic acid 1 is an LNA-type nucleoside derivative.</p>Formule :C32H32N2O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :572.61GSK4418959
CAS :<p>GSK4418959 (IDE275) is a selective WRN helicase inhibitor that blocks ATPase and DNA unwinding, serving as a tool in MSI-H cancer research.</p>Formule :C31H30F4N4O5SDegré de pureté :99.141%Couleur et forme :SoildMasse moléculaire :646.652'-Azido-2'-deoxyuridine
CAS :<p>2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor with anti-cancer activity.</p>Formule :C9H11N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :269.21RI(dl)-2 TFA
CAS :RI(dl)-2 TFA inhibits RAD51 D-loop at 11.1 μM and HR in human cells at 3.0 μM.Formule :C19H17N3Couleur et forme :SolidMasse moléculaire :287.36E-982
CAS :<p>E-982 is derived from the reference compound.</p>Formule :C25H31NO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.58Halofuginone
CAS :<p>Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.</p>Formule :C16H17BrClN3O3Degré de pureté :99.53%Couleur et forme :Off-White SolidMasse moléculaire :414.683,4-Dihydroxybenzylamine hydrobromide
CAS :<p>3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.</p>Formule :C7H10BrNO2Degré de pureté :98.49%Couleur et forme :Light Beige Crystalline PowderMasse moléculaire :220.06E3330
CAS :<p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>Formule :C21H30O6Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :378.46BMVC
CAS :<p>BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities.</p>Formule :C28H25I2N3Couleur et forme :SolidMasse moléculaire :657.33Thiarabine
CAS :<p>Thiarabine displays effective anti-tumor activity. It also inhibition of DNA synthesis.</p>Formule :C9H13N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :259.28BzDANP
CAS :<p>BzDANP is a modulator of pre-miR-29a maturation by Dicer.</p>Formule :C18H24N6Couleur et forme :SolidMasse moléculaire :324.42SEC inhibitor KL-2
CAS :<p>KL-2: potent SEC inhibitor, selectively disrupts AFF4-CCNT1, dose-dependent, Ki: 1.50 μM.</p>Formule :C17H13ClFNO3Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :333.74SPC-839
CAS :<p>SPC-839 is an IKK-2 Inhibitor with oral activity.</p>Formule :C18H14N4O3SCouleur et forme :SolidMasse moléculaire :366.39AM-TS23
CAS :<p>AM-TS23 is used as a DNA polymerase lambda and beta inhibitor.</p>Formule :C17H12N2O3S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :388.48ML366
CAS :<p>ML366 is a Vibrio cholerae Quorum Sensing inhibitor Acting via the LuxO response regulator.</p>Formule :C17H19N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.35Meturedepa
CAS :<p>Meturedepa is an antineoplastic agent.</p>Formule :C11H22N3O3PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :275.28MTH1-IN-2
CAS :<p>MTH1-IN-2 is an inhibitor of MutT homolog 1 (MTH1), with anti-tumor activity.</p>Formule :C24H27N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :469.558-Azido-ADP disodium
CAS :<p>8-Azido-ADP (disodium) is a covalent inhibitor of ADP/ATP exchange in mitochondria, causing irreversible inhibition in light.</p>Formule :C10H13N8NaO10P2Couleur et forme :SolidMasse moléculaire :490.1972-Keto-D-galactose
CAS :<p>2-Keto-D-galactose inhibits DNA synthesis and inhibits the proliferation of in vitro grown Ehrlich ascites tumor cells.</p>Formule :C6H10O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :178.14DHX9-IN-1
CAS :<p>DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].</p>Formule :C21H21F2N5O3SCouleur et forme :SolidMasse moléculaire :461.49S-(N-PhenethylthiocarbaMoyl)-L-cysteine
CAS :<p>PEITC-Cys: anticarcinogenic, antileukemic, inhibits DNA synthesis in HL60, P450 inhibitor.</p>Formule :C12H16N2O2S2Couleur et forme :SolidMasse moléculaire :284.4Crisnatol
CAS :<p>Crisnatol (BWA770U) is an oral anticancer DNA intercalator, toxic to breast cancer cells, not skin fibroblasts.</p>Formule :C23H23NO2Couleur et forme :SolidMasse moléculaire :345.43Direct Black 38 free acid
CAS :<p>Ferristatin II (Direct Black 38 free acid) is a polysulphonated dye and promotes the degradation of transferrin receptor-1 in vitro and in vivo.</p>Formule :C34H27N9O7S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :737.77Codon readthrough inducer 1
CAS :<p>Codon readthrough inducer 1 contains pyrimidine bases and shows good readthrough activity.</p>Formule :C15H11N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :313.26MS0017509
CAS :<p>MS0017509 is a DNA damage repair inhibitor.</p>Formule :C11H10N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :198.22CTP Synthetase-IN-1
CAS :<p>CTP Synthetase-IN-1 is a cytidine 5'-triphosphate synthetase (CTPS) inhibitor with antitumor activity for the study of arthritis and rheumatoid arthritis.</p>Formule :C20H19F3N6O3S2Degré de pureté :98.11% - 99.18%Couleur et forme :SolidMasse moléculaire :512.53DENV-IN-4
CAS :<p>DENV-IN-4: Effective DENV inhibitor (EC50=4.79 μM), low toxicity (CC50>100 μM), and strong selectivity (SI>20.9); suppresses DENV2 and RdRp.</p>Formule :C28H32N4O4SiCouleur et forme :SolidMasse moléculaire :516.66JNJ-9676
CAS :<p>JNJ-9676 is an orally active inhibitor of the coronavirus membrane protein, thereby blocking viral assembly and release.coronavirus and SARS-CoV.</p>Formule :C28H21F2N5O2Degré de pureté :99.83%Couleur et forme :SoildMasse moléculaire :497.5IDD388
CAS :<p>IDD388 is a selective and potent aldose reductase (ALR2) inhibitor with antitumor activity that inhibits the ALR1 receptor.</p>Formule :C16H12BrClFNO4Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :416.63TDRL-X80
CAS :<p>TDRL-X80 inhibits XPA DNA binding; effective on single, double, and cisplatin-damaged DNA; IC50: 18-29 μM (FP), 21-39 μM (ELISA).</p>Formule :C23H15ClN2O6Couleur et forme :SolidMasse moléculaire :450.83RHI002-Me
CAS :<p>RHI002-Me is a methylated derivative of RHI002, a selective inhibitor of human RNaseH2.</p>Formule :C18H19N3O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :373.49Antitumor agent-84
<p>Antitumor agent-84 stabilizes G-quadruplex DNA, exhibits potent anti-tumor effects.</p>Formule :C24H31N7Couleur et forme :SolidMasse moléculaire :417.55DDD100097
CAS :<p>DDD100097 is a N-myristoyltransferase inhibitor with potential inhibitory effects on Trypanosoma brucei, which can be used to study neurological disorders.</p>Formule :C22H30Cl2F2N4O2SDegré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :523.47Werner syndrome RecQ helicase-IN-4
CAS :<p>Werner syndrome RecQ helicase-IN-4 is a WRN inhibitor with anticancer and anti-proliferative activity, used in colorectal and gastric cancer research.</p>Formule :C32H33F3N8O5Degré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :666.65HHL-6
CAS :<p>HHL-6 is a c-Fos and BDNF protein expression modulator.</p>Formule :C19H26N2O3Couleur et forme :SolidMasse moléculaire :330.42CM03
CAS :<p>CM03 is a cell-selective G-quadruplex ligand with anti-cancer activity, stabilizing G4 genes, useful in pancreatic cancer research.</p>Formule :C34H44N6O6Degré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :632.75Nitracrine
CAS :<p>Nitracrine: a 1-nitroacridine, hypoxia-selective, anti-tumor agent; inhibits RNA synthesis, binds DNA reversibly and forms covalent adducts.</p>Formule :C18H20N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.38Laromustine
CAS :<p>Laromustine (VNP40101M) is a sulfonyl hydrolysis alkylation prodrug for cancer treatment with significant anticancer activity, inhibiting thioredoxin reductase.</p>Formule :C6H14ClN3O5S2Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :307.7810-Formyl-5,8-dideazafolic acid
CAS :<p>10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor.</p>Formule :C22H21N5O7Degré de pureté :96.04%Couleur et forme :SolidMasse moléculaire :467.43CID 5951923
CAS :<p>CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.</p>Formule :C16H18N2O7SDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :382.39360A iodide
CAS :<p>360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).</p>Formule :C27H23I2N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :703.31Synucleozid
CAS :<p>Synucleozid is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.</p>Formule :C22H20N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :368.43Glucocorticoid receptor modulator 1
CAS :<p>Glucocorticoid receptor modulator 1 is a orally NF-κB and AP-1 inhibitor, inflammatory factors IL-6, IL-1β, TNF-α, and MMP-13, alleviating skin inflammation.</p>Formule :C24H23ClN2O4SDegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :470.97Bofumustine
CAS :<p>Bofumustine is a chloroethyl nitrosourea with anti tumor properties.</p>Formule :C18H21ClN4O9Couleur et forme :SolidMasse moléculaire :472.83ML372
CAS :<p>ML372 is a potent and selective SMN Modulator (EC50 = 12 nM, 325% increase inSMN2) with good potency, pharmacokinetics, tolerance, and CNS penetration.</p>Formule :C18H20N2O4SCouleur et forme :SolidMasse moléculaire :360.43Fozivudine tidoxil
CAS :<p>Fozivudine tidoxil, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.</p>Formule :C35H64N5O8PSCouleur et forme :SolidMasse moléculaire :745.952-Fluoroadenine
CAS :<p>2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.</p>Formule :C5H4FN5Degré de pureté :98.84% - 99.62%Couleur et forme :White To Light Yellow Crystal PowderMasse moléculaire :153.12D-Xylofuranose, 1,2,3,5-tetraacetate
CAS :<p>1,2,3,5-Tetra-O-acetyl-D-xylofuranose is a starting material for the synthesis of nucleosides.</p>Formule :C13H18O9Couleur et forme :SolidMasse moléculaire :318.28Werner syndrome RecQ helicase-IN-3
CAS :<p>Potent WRN inhibitor, Werner syndrome RecQ helicase-IN-3, is orally active with 0.06 µM IC50; exhibits antiproliferative and anticancer effects.</p>Formule :C31H30ClF3N8O5Couleur et forme :SolidMasse moléculaire :687.07Crisnatol mesylate
CAS :<p>Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity.</p>Formule :C24H27NO5SCouleur et forme :SolidMasse moléculaire :441.54HBV-IN-16
CAS :<p>HBV-IN-16, a quinoline derivative, inhibits HBV cccDNA, key for viral replication (from patent WO2019121357A1).</p>Formule :C22H20ClNO4Couleur et forme :SolidMasse moléculaire :397.85Picoplatin
CAS :<p>Picoplatin, an anti-cancer agent overcoming platinum resistance, alkylates DNA to block replication, transcription, and induce apoptosis.</p>Formule :C6H10Cl2N2PtDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :376.14BPIC
CAS :<p>BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals.</p>Formule :C27H20N2O5Couleur et forme :SolidMasse moléculaire :452.46HBV-IN-22
CAS :<p>HBV-IN-22 (Compound LC5f) is an HBV DNA replication inhibitor that acts on both wild-type HBV (IC50: 0.71 μM) and drug-resistant HBV (IC50: 0.84 μM).</p>Formule :C26H29N3O2S2Couleur et forme :SolidMasse moléculaire :479.66Braco-19 trihydrochloride
CAS :<p>BRACO19 3HCl inhibits telomerase, blocking its capping function, and prevents HAdV viral replication.</p>Formule :C35H46Cl3N7O2Degré de pureté :98.74%Couleur et forme :SolidMasse moléculaire :703.14GW8510
CAS :<p>GW8510 is a CDK2 and RRM2 inhibitor that affects DNA synthesis and antiproliferation in tumor cells. In mammalian aging models, GW851 prolongs lifespan.</p>Formule :C21H15N5O3S2Degré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :449.51Datelliptium chloride
CAS :<p>Datelliptium chloride is a DNA-intercalating agent derived from ellipticine. Datelliptium chloride shows anti-tumor activities.</p>Formule :C23H28ClN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :397.94UIAA-II-232
CAS :<p>UIAA-II-232 (compound 19b) is a potent inhibitor of DNA gyrase catalytic (IC 50= 3.5 μM).</p>Formule :C20H24FN5O3Couleur et forme :SolidMasse moléculaire :401.43Apricitabine
CAS :<p>Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-</p>Formule :C8H11N3O3SDegré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :229.26ST7612AA1
CAS :<p>ST7612AA1: potent, oral HDAC inhibitor; reactivates HIV-1 latency; shows antitumor effects; may study malaria.</p>Formule :C20H27N3O4SDegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :405.51Zelpolib
CAS :<p>Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.</p>Formule :C22H21N3O5S2Degré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :471.55Homocarbonyltopsentin
CAS :<p>Homocarbonyltopsentin: Small molecule, binds TSL2 pentaloops, enhances SMN2 E7 splicing, EC50 16 μM.</p>Formule :C21H14N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :370.363'-Deoxyuridine-5'-triphosphate
CAS :<p>3'-dUTP, a nucleotide analogue, competitively inhibits RNA polymerases I & II, with a Ki of 2.0 µM.</p>Formule :C9H15N2O14P3Couleur et forme :SolidMasse moléculaire :468.14Phelorphan
CAS :<p>Phelorphan is an inhibitor of enkephalinase.</p>Formule :C20H22N2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :386.46Beaucage reagent
CAS :<p>Beaucage reagent, which is found to be effective in causing DNA cleavage.</p>Formule :C7H4O3S2Degré de pureté :98.50%Couleur et forme :White To Off-White PowderMasse moléculaire :200.23JFN05510
CAS :<p>Compound: 3'-O-tert-BDMS-5'-O-DMT-N2-IBG 2'-CE phosphoramidite; has anticancer properties and activates enzymes.</p>Formule :C50H68N7O9PSiCouleur et forme :SolidMasse moléculaire :970.18Triaziquone
CAS :<p>Triaziquone is an alkylating agent that can react with DNA to form intrastrand crosslinks.</p>Formule :C12H13N3O2Couleur et forme :SolidMasse moléculaire :231.25AS-136A
CAS :<p>AS-136A is an orally active MV RdRp inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.</p>Formule :C17H19F3N4O3SDegré de pureté :98.52%Couleur et forme :SolidMasse moléculaire :416.42HIPP
CAS :<p>HIPP is a highly selective inhibitor of antineoplastic CtBP.</p>Formule :C9H9NO3Couleur et forme :SolidMasse moléculaire :179.17BMH-22
CAS :<p>BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>Formule :C16H17N3Couleur et forme :SolidMasse moléculaire :251.33Phen-DC3
CAS :<p>Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases (IC50s of 65±6 and 50±10 nM, respectively).</p>Formule :C34H26N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :550.61NPD9948
CAS :<p>NPD9948 is a competitive inhibitor of MTH1.</p>Formule :C13H14N6Couleur et forme :SolidMasse moléculaire :254.29MLAF50
CAS :<p>MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.</p>Formule :C15H12I2O4Couleur et forme :SolidMasse moléculaire :510.06HIV-1 inhibitor-43
CAS :<p>HIV-1 Inhibitor-43 suppresses HIV-1, with EC50: 21.3 nM (Y188L), 6.2 nM (K103N-Y181C), <0.7 nM (K103N/Y181C), and lowers HIV RNA/p24 protein.</p>Formule :C24H21ClN2O4SCouleur et forme :SolidMasse moléculaire :468.95HBV-IN-4
CAS :<p>HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.</p>Formule :C24H19ClFN5O3Couleur et forme :SolidMasse moléculaire :479.89Cylindrospermopsin
CAS :<p>Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.</p>Formule :C15H21N5O7SCouleur et forme :SolidMasse moléculaire :415.42EGFR/HER2/TS-IN-2
CAS :<p>EGFR/HER2/TS-IN-2: Strong EGFR, HER2 & TS inhibitor; EGFR IC50=0.173μM, HER2 IC50=0.125μM, TS IC50=1.12μM; kills MDA-MB-231 cells (IC50=1.69μM).</p>Formule :C26H21N7OS2Couleur et forme :SolidMasse moléculaire :511.62BAY-707
CAS :<p>BAY-707: tolerable in mice, no anticancer efficacy; potent, selective MTH1 inhibitor, IC50 = 2.3 nM; good PK profile.</p>Formule :C15H20N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :288.3415(S)-HpETE
CAS :<p>15(S)-HpETE is a product of arachidonic acid formed in the 15-lipoxygenase pathway and inhibits angiogenesis.</p>Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.47REV7/REV3L-IN-1
CAS :<p>REV7/REV3L-IN-1 is a inhibitor of REV7/REV3L interaction(IC50 of 78 μM),</p>Formule :C19H21N3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :371.45FLDP-5
CAS :<p>FLDP-5: BBB-penetrant curcuminoid, induces ROS, DNA damage, S phase arrest, suppresses tumors in LN-18 cells.</p>Formule :C21H21NO5Couleur et forme :SolidMasse moléculaire :367.4HBV-IN-21
CAS :<p>HBV-IN-21 inhibits HBV DNA replication (IC50: 2.2 μM) and binds HBV capsid protein well (KD: 60.0 μM).</p>Formule :C17H17FN4OS2Couleur et forme :SolidMasse moléculaire :376.47CAY10760
CAS :<p>CAY10760 inhibits RAD51-BRCA2 interaction (EC50=19 μM), reduces homologous recombination by 54%, and hinders BxPC-3/Capan-1 cancer cell proliferation.</p>Formule :C28H24ClN3O3Couleur et forme :SolidMasse moléculaire :485.96BMH-23
CAS :<p>BMH-23 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>Formule :C15H15N3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :237.3Halofuginone hydrobromide
CAS :<p>Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.</p>Formule :C16H17BrClN3O3·HBrDegré de pureté :97.01% - 99.73%Couleur et forme :SolidMasse moléculaire :495.59Enocitabine
CAS :<p>Enocitabine is a nucleoside analog.</p>Formule :C31H55N3O6Degré de pureté :97.22%Couleur et forme :SolidMasse moléculaire :565.78ERCC1-XPF-IN-1
CAS :<p>ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.</p>Formule :C28H32ClN5O2Couleur et forme :SolidMasse moléculaire :506.04cp028
CAS :<p>cp028 inhibits pre-mRNA splicing in vitro.</p>Formule :C23H17FN2O4Couleur et forme :SolidMasse moléculaire :404.395,10-Dideazaaminopterin
CAS :<p>5,10-Dideazaaminopterin is an antileukemic drug.</p>Formule :C21H22N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.44IACS-4759
CAS :<p>IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.</p>Formule :C10H17N3O2Couleur et forme :SolidMasse moléculaire :211.26HBV-IN-14
CAS :<p>HBV-IN-14: a pyridinopyrimidinone, potent cccDNA inhibitor for HBV study (patent WO2021190502A1, comp 5).</p>Formule :C22H21ClN2O5Couleur et forme :SolidMasse moléculaire :428.87AB-182
CAS :<p>AB-182 is an aziridine derivative with antitumor activity.</p>Formule :C11H22N3O4PCouleur et forme :SolidMasse moléculaire :291.28BMVC2
CAS :<p>BMVC2 (o-BMVC), a carbazole derivative of BMVC, is a G-quadruplex (G4) stabilizer.</p>Formule :C28H25I2N3Couleur et forme :SolidMasse moléculaire :657.33MMV688845
CAS :<p>MMV688845: NTM RNA polymerase inhibitor, kills Mycobacterium abscessus, and fights TB.</p>Formule :C24H25N3O3SCouleur et forme :SolidMasse moléculaire :435.54CBL 0100 free base
CAS :<p>CBL0100 is an inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation.</p>Formule :C24H26N2O2Degré de pureté :98.18% - 98.86%Couleur et forme :SolidMasse moléculaire :374.48CB 3717
CAS :<p>CB 3717 is an enzyme inhibitor, antineoplastic agent, folic acid antagonist.</p>Formule :C24H23N5O6Couleur et forme :SolidMasse moléculaire :477.47NSC666715
CAS :<p>NSC666715 is the strand-displacement activity of DNA polymerase inhibitor.</p>Formule :C15H13Cl2N5O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.33Antitumor agent-85
<p>Antitumor agent-85 stabilizes G4-DNA with potent anti-tumor effects.</p>Formule :C24H33N7Couleur et forme :SolidMasse moléculaire :419.57Antibacterial agent 124
CAS :<p>Antibacterial agent 124 inhibits Sa ProRS with an IC50 of 0.18 μM.</p>Formule :C16H17ClFN3O2Couleur et forme :SolidMasse moléculaire :337.78CGP 53353
CAS :<p>CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.</p>Formule :C20H13F2N3O2Degré de pureté :98.11%Couleur et forme :SolidMasse moléculaire :365.33HBV-IN-15
CAS :<p>HBV-IN-15, a flavone derivative, is a potent cccDNA inhibitor, potentially aiding HBV research.</p>Formule :C24H23ClO6Couleur et forme :SolidMasse moléculaire :442.89SMN-C2
CAS :<p>SMN-C2, a SMN2 gene splicing regulator, is an RNA-binding ligand that regulates pre-mRNA splicing and has potential for studying spinal muscular atrophy.</p>Formule :C24H27N5O2Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :417.5CHD1Li 6.11
CAS :<p>CHD1Li 6.11 inhibits CHD1L protein (IC50: 3.3 µM), shrinks CRC tumors in vivo, and is orally active.</p>Formule :C21H22BrN5OSDegré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :472.4Galocitabine
CAS :<p>Galocitabine (Neofrutulon), a thymidylate synthase inhibitor, is used potentially for the treatment of cancer.</p>Formule :C19H22FN3O8Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :439.396-Hydroxy-DOPA
CAS :<p>6-Hydroxy-DOPA is an allosteric inhibitor of RAD52, it inhibits proliferation of BRCA-deficient cancer cells in vitro and also inhibits APE1.</p>Formule :C9H11NO5Degré de pureté :97.78% - 97.95%Couleur et forme :SolidMasse moléculaire :213.19ERCC1-XPF-IN-2
CAS :<p>ERCC1-XPF-IN-2: Nucleotide repair active, boosts cisplatin, inhibits ERCC1-XPF (IC50: 0.6 μM).</p>Formule :C15H13Cl2NO3Degré de pureté :98.21%Couleur et forme :SolidMasse moléculaire :326.17Anticancer agent 73
CAS :<p>Anticancer agent 73 inhibits TRBP, disrupting TRBP-Dicer, and hinders HCC growth and spread by altering HCC miRNA and protein expression.</p>Formule :C14H15NO4Degré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :261.27TTP-8307
CAS :TTP-8307 is an antiviral compound that inhibits the replication of rhinoviruses and enteroviruses and is used in the study of viral infections.Formule :C27H21FN4ODegré de pureté :98.95%Couleur et forme :SolidMasse moléculaire :436.48ZIM
CAS :<p>ZIM, from 4-Aminoantipyrine, induces DNA and chromosomal damage, cell death, and phagocytosis, with potential in cancer therapy.</p>Formule :C20H19N3O3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :349.38Talviraline
CAS :<p>Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in a</p>Formule :C15H20N2O3S2Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :340.46116-9e
CAS :<p>116-9e (MAL2-11B) is an Hsp70 chaperone DNAJA1 inhibitor with antiviral properties, inhibits SV40 replication, and can be used to study cancer drug resistance.</p>Formule :C31H32N2O5Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :512.6Caracemide
CAS :<p>Caracemide (NSC-253272) inhibits the enzyme ribonucleotide reductase of Escherichia coli. Caracemide can be used in anticancer studies.</p>Formule :C6H11N3O4Degré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :189.17Cytembena
CAS :<p>Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.</p>Formule :C11H8BrNaO4Degré de pureté :99.35%Couleur et forme :White PowderMasse moléculaire :307.07D-I03
CAS :<p>D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM.</p>Formule :C23H36N6SDegré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :428.64DDRI-18
CAS :<p>DDRI-18 is an inhibitor that regulates the DNA damage response, has anticancer activity, and inhibits non-homologous end-joining (NHEJ) DNA repair.</p>Formule :C26H20N6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :416.48RP-6685
CAS :<p>RP-6685 is a potent, selective DNA Polθ inhibitor with strong oral efficacy, an IC50 of 5.8 nM, and marked antitumor effects in mice.</p>Formule :C22H14F7N5ODegré de pureté :99.65%Couleur et forme :SoildMasse moléculaire :497.37FAICAR
CAS :<p>FAICAR (5-Formamidoimidazole-4-carboxamide ribotide), a purine nucleotide, plays a crucial role in metabolic processes.</p>Formule :C10H15N4O9PCouleur et forme :SolidMasse moléculaire :366.223-Cyanovinylcarbazole phosphoramidite
CAS :<p>3-Cyanovinylcarbazole phosphoramidite: an antiviral, hinders viral DNA synthesis, modifies ribonucleotides.</p>Formule :C50H53N4O6PCouleur et forme :SolidMasse moléculaire :836.95DNA polymerase-IN-3
CAS :<p>DNA polymerase-IN-3 (Compd 5b), a coumarin derivative, demonstrates inhibitory activity against Taq DNA polymerase and has potential applications in</p>Formule :C13H12O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :232.23Votoplam
CAS :<p>Votoplam functions as a gene splicing modulator, employed in the inhibition of Huntington's disease [1].</p>Formule :C21H25N9ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.485,6,7,8-Tetrahydro-8-deazahomofolic acid
CAS :<p>5,6,7,8-Tetrahydro-8-deazahomofolic acid is a potential thymidylate synthase (TS) inhibitor and other folate related enzymes inhibitor.</p>Formule :C21H26N6O6Couleur et forme :SolidMasse moléculaire :458.475-DACTHF
CAS :<p>5,11-methenyltetrahydrohomofolate blocks GAR & AIR transformylase; used as an anti-purine drug.</p>Formule :C19H24N6O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :432.43Diazoketone methotrexate
CAS :<p>Diazoketone methotrexate is an analog of methotrexate with potential antitumor activity.</p>Formule :C21H22N10O4Couleur et forme :SolidMasse moléculaire :478.46TAS-114
CAS :<p>TAS-114 is a dUTPase and DPD inhibitor that modulates catabolic pathways to improve systemic availability of 5-FU.</p>Formule :C21H29N3O6SDegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :451.54WRN inhibitor 3
CAS :<p>WRN Inhibitor 3 (example 110), a cyclic vinyl sulfone-based compound, serves as an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN).</p>Formule :C20H20N2O5SCouleur et forme :SolidMasse moléculaire :400.45UNC-2170
CAS :<p>UNC-2170 (UNC2170 Maleate) is the methyl-lysine binding protein, 53BP1 ligand.</p>Formule :C14H21BrN2ODegré de pureté :97.44%Couleur et forme :SolidMasse moléculaire :313.23BVDU 5′-Triphosphate
CAS :<p>BVDU 5′-Triphosphate is an antiviral agent labeled with 5′-Triphosphate that specifically targets viral DNA polymerase.</p>Formule :C11H16BrN2O14P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :573.088-Azahypoxanthine
CAS :<p>8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.</p>Formule :C4H3N5ODegré de pureté :99.66%Couleur et forme :Light Yellow To Light Beige Fine CrystallineMasse moléculaire :137.19-Deazaguanine
CAS :<p>9-Deazaguanine is a nucleoside analogue exhibiting inhibitory activity against bovine purine nucleoside phosphorylase (PNP).</p>Formule :C6H6N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :150.14WRN inhibitor 1
CAS :<p>WRN Inhibitor 1 (example 7) is an inhibitor of the Werner Syndrome ATP-dependent helicase enzyme (WRN), selectively targeting its helicase domain.</p>Formule :C16H13FN2O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :348.35UNC2170 maleate
CAS :<p>53BP1-binding protein 1 (53BP1) engages with dimethylated lysine 20 on histone 4 (H4K20me2) through its tandem tudor domains within a homodimer configuration, crucial for the DNA damage response. UNC2170, a micromolar 53BP1 ligand, selectively interacts with this site, demonstrating at least 17-fold preference for 53BP1 over similar proteins. This interaction occurs in a pocket formed by the 53BP1's tudor domains. Moreover, UNC2170 acts as an antagonist to 53BP1 in cellular lysates, effectively inhibiting class switch recombination, a process dependent on the functional 53BP1 tudor domain, thus confirming its cellular activity.</p>Formule :C14H21BrN2OC4H4O4Couleur et forme :SolidMasse moléculaire :429.31DAM-IN-1
CAS :<p>DMA-IN-1 is a DNA adenine methyltransferase (DAM) inhibitor with an IC50 value of 48 μM.</p>Formule :C16H17NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :287.31Pencitabine
CAS :<p>Pen is an oral cancer drug that blocks DNA synthesis by inhibiting key enzymes and integrating into DNA.</p>Formule :C15H20F3N3O6Couleur et forme :SolidMasse moléculaire :395.33COH1
CAS :<p>COH1 is a ribonucleotide reductase (RR) inhibitor utilized in research pertaining to cancer, mitochondrial diseases, and neurodegenerative disorders [1].</p>Formule :C11H10N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :250.27WRN inhibitor 2
CAS :<p>WRN Inhibitor 2 (example 118), a potent inhibitor of the WRN (Werner Syndrome ATP-dependent helicase enzyme), exhibits a pIC50 value of 7.0 or greater [1].</p>Formule :C15H11F3N2O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :420.38H3B-968
CAS :<p>H3B-968 is a potent inhibitor of Werner syndrome protein (WRN) with an IC50 of approximately 10 nM, effectively targeting its helicase, ATPase, and exonuclease</p>Formule :C22H18F6N4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :548.46AVG-233
CAS :<p>AVG-233 is an RNA-dependent RNA polymerase (RdRp) inhibitor with antiviral activity for the study of respiratory syncytial virus infections.</p>Formule :C26H22ClN5O3Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :487.94hDHODH-IN-1
CAS :<p>hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.</p>Formule :C17H14N2O2Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :278.31
