Synthèse ADN/ARN
Les inhibiteurs de la synthèse de l'ADN et de l'ARN sont des composés qui interfèrent avec les processus de réplication et de transcription dans les cellules, empêchant ainsi la production de matériel génétique essentiel. Ces inhibiteurs peuvent cibler diverses enzymes et protéines impliquées dans la synthèse des acides nucléiques, ce qui en fait des outils précieux pour étudier les mécanismes de réplication, de transcription et de traduction. Ils sont également utilisés dans le développement de traitements contre les infections et le cancer. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de la synthèse de l'ADN/ARN pour soutenir vos recherches en biologie moléculaire, virologie et développement thérapeutique.
711 produits trouvés pour "Synthèse ADN/ARN"
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Didox
CAS :<p>Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.</p>Formule :C7H7NO4Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :169.13(S)-crizotinib
CAS :<p>(S)-crizotinib (ent-crizotinib) （IC50 of 72 nM）, an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.</p>Formule :C21H22Cl2FN5ODegré de pureté :98.52% - 99.47%Couleur et forme :SolidMasse moléculaire :450.34COH29
CAS :<p>COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.</p>Formule :C22H16N2O5SDegré de pureté :97.04% - 98.92%Couleur et forme :SolidMasse moléculaire :420.44Tempo
CAS :<p>Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a</p>Formule :C9H18NODegré de pureté :98.35%Couleur et forme :Orange Crystals Or PowderMasse moléculaire :156.25Fialuridine
CAS :<p>Fialuridine (DRG-0098), a DNA polymerase inhibitor, shows strong anti-HBV effects both in vitro and in vivo.</p>Formule :C9H10FIN2O5Degré de pureté :99.71% - 99.88%Couleur et forme :Less Crystals Colourless CrystalsMasse moléculaire :372.09TH287 hydrochloride
CAS :<p>TH287 inhibits MTH1 (IC50: 0.8 nM), causing DNA damage in cancer cells through oxidized dNTP incorporation, leading to cytotoxicity in mouse xenografts.</p>Formule :C11H11Cl3N4Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :305.59Neobavaisoflavone
CAS :<p>Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.</p>Formule :C20H18O4Degré de pureté :99.31% - 99.87%Couleur et forme :SolidMasse moléculaire :322.35PolQi2
CAS :<p>PolQi2 is a Polθ inhibitor that suppresses the helicase activity of Polθ, and when combined with AZD7648.</p>Formule :C21H16ClN5O3SDegré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :453.92'-O-(2-Methoxyethyl)adenosine
CAS :2'-O-(2-Methoxyethyl)adenosine is a nucleoside analog used to improve RNA target affinity and nuclease resistance of therapeutic oligonucleotides in preclin.Formule :C13H19N5O5Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :325.325-Bromouridine
CAS :<p>5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.</p>Formule :C9H11BrN2O6Degré de pureté :99.89%Couleur et forme :White PowderMasse moléculaire :323.1Locked nucleic acid 1
CAS :<p>Locked nucleic acid 1 is an LNA-type nucleoside derivative.</p>Formule :C32H32N2O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :572.61VVD-214
CAS :<p>VVD-214 (RO7589831) is a WRN deconjugation enzyme lethal-mutagenic inhibitor that can be used to study proliferative diseases.</p>Formule :C20H21F2N3O4SDegré de pureté :99.24%Couleur et forme :SoildMasse moléculaire :437.46GSK4418959
CAS :<p>GSK4418959 (IDE275) is a selective WRN helicase inhibitor that blocks ATPase and DNA unwinding, serving as a tool in MSI-H cancer research.</p>Formule :C31H30F4N4O5SDegré de pureté :99.141%Couleur et forme :SoildMasse moléculaire :646.65Metribuzin
CAS :<p>Metribuzin is a selective herbicide used on crops like soybeans and potatoes. It inhibits photosynthesis and is a persistent groundwater contaminant.</p>Formule :C8H14N4OSDegré de pureté :99.07%Couleur et forme :Colorless Crytals Metribuzin Is A Colorless Crystalline Solid Used As An Herbicide (Niosh 2016)Masse moléculaire :214.29DHX9-IN-8
CAS :<p>DHX9-IN-8 (Compound 6) functions as an inhibitor of the RNA helicase DHX9, exhibiting an EC50 of 3.4 μM for cellular target engagement within DHX9. It is primarily utilized in cancer research [1].</p>Formule :C18H16N2O3S2Couleur et forme :SolidMasse moléculaire :372.46RI(dl)-2 TFA
CAS :RI(dl)-2 TFA inhibits RAD51 D-loop at 11.1 μM and HR in human cells at 3.0 μM.Formule :C19H17N3Couleur et forme :SolidMasse moléculaire :287.36E-982
CAS :<p>E-982 is derived from the reference compound.</p>Formule :C25H31NO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.582'-Azido-2'-deoxyuridine
CAS :<p>2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor with anti-cancer activity.</p>Formule :C9H11N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :269.21Halofuginone
CAS :<p>Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.</p>Formule :C16H17BrClN3O3Degré de pureté :99.53%Couleur et forme :Off-White SolidMasse moléculaire :414.68E3330
CAS :<p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>Formule :C21H30O6Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :378.463,4-Dihydroxybenzylamine hydrobromide
CAS :<p>3,4-Dihydroxybenzylamine hydrobromide inhibits DNA polymerase and melanoma growth, varying with tyrosinase activity.</p>Formule :C7H10BrNO2Degré de pureté :98.49%Couleur et forme :Light Beige Crystalline PowderMasse moléculaire :220.06BzDANP
CAS :<p>BzDANP is a modulator of pre-miR-29a maturation by Dicer.</p>Formule :C18H24N6Couleur et forme :SolidMasse moléculaire :324.42Zelpolib
CAS :<p>Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.</p>Formule :C22H21N3O5S2Degré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :471.55SEC inhibitor KL-2
CAS :<p>KL-2: potent SEC inhibitor, selectively disrupts AFF4-CCNT1, dose-dependent, Ki: 1.50 μM.</p>Formule :C17H13ClFNO3Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :333.74SPC-839
CAS :<p>SPC-839 is an IKK-2 Inhibitor with oral activity.</p>Formule :C18H14N4O3SCouleur et forme :SolidMasse moléculaire :366.39AM-TS23
CAS :AM-TS23 is used as a DNA polymerase lambda and beta inhibitor.Formule :C17H12N2O3S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :388.48ML366
CAS :<p>ML366 is a Vibrio cholerae Quorum Sensing inhibitor Acting via the LuxO response regulator.</p>Formule :C17H19N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :329.35Meturedepa
CAS :<p>Meturedepa is an antineoplastic agent.</p>Formule :C11H22N3O3PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :275.28MTH1-IN-2
CAS :<p>MTH1-IN-2 is an inhibitor of MutT homolog 1 (MTH1), with anti-tumor activity.</p>Formule :C24H27N3O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :469.558-Azido-ADP disodium
CAS :<p>8-Azido-ADP (disodium) is a covalent inhibitor of ADP/ATP exchange in mitochondria, causing irreversible inhibition in light.</p>Formule :C10H13N8NaO10P2Couleur et forme :SolidMasse moléculaire :490.197Thiarabine
CAS :<p>Thiarabine displays effective anti-tumor activity. It also inhibition of DNA synthesis.</p>Formule :C9H13N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :259.28S-(N-PhenethylthiocarbaMoyl)-L-cysteine
CAS :<p>PEITC-Cys: anticarcinogenic, antileukemic, inhibits DNA synthesis in HL60, P450 inhibitor.</p>Formule :C12H16N2O2S2Couleur et forme :SolidMasse moléculaire :284.42-Keto-D-galactose
CAS :<p>2-Keto-D-galactose inhibits DNA synthesis and inhibits the proliferation of in vitro grown Ehrlich ascites tumor cells.</p>Formule :C6H10O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :178.14Direct Black 38 free acid
CAS :<p>Ferristatin II (Direct Black 38 free acid) is a polysulphonated dye and promotes the degradation of transferrin receptor-1 in vitro and in vivo.</p>Formule :C34H27N9O7S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :737.77Codon readthrough inducer 1
CAS :Codon readthrough inducer 1 contains pyrimidine bases and shows good readthrough activity.Formule :C15H11N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :313.26MS0017509
CAS :<p>MS0017509 is a DNA damage repair inhibitor.</p>Formule :C11H10N4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :198.22IDD388
CAS :IDD388 is a selective and potent aldose reductase (ALR2) inhibitor with antitumor activity that inhibits the ALR1 receptor.Formule :C16H12BrClFNO4Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :416.63DHX9-IN-1
CAS :<p>DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].</p>Formule :C21H21F2N5O3SCouleur et forme :SolidMasse moléculaire :461.49JNJ-9676
CAS :<p>JNJ-9676 is an orally active inhibitor of the coronavirus membrane protein, thereby blocking viral assembly and release.coronavirus and SARS-CoV.</p>Formule :C28H21F2N5O2Degré de pureté :99.83%Couleur et forme :SoildMasse moléculaire :497.5Crisnatol
CAS :<p>Crisnatol (BWA770U) is an oral anticancer DNA intercalator, toxic to breast cancer cells, not skin fibroblasts.</p>Formule :C23H23NO2Couleur et forme :SolidMasse moléculaire :345.43DENV-IN-4
CAS :<p>DENV-IN-4: Effective DENV inhibitor (EC50=4.79 μM), low toxicity (CC50>100 μM), and strong selectivity (SI>20.9); suppresses DENV2 and RdRp.</p>Formule :C28H32N4O4SiCouleur et forme :SolidMasse moléculaire :516.66CGP 53353
CAS :<p>CGP 53353 (DAPH-7) is a PKC inhibitor with inhibitory effects on PKCβII and PKCβI and can be used to study atherosclerosis.</p>Formule :C20H13F2N3O2Degré de pureté :98.11%Couleur et forme :SolidMasse moléculaire :365.33CTP Synthetase-IN-1
CAS :CTP Synthetase-IN-1 is a cytidine 5'-triphosphate synthetase (CTPS) inhibitor with antitumor activity for the study of arthritis and rheumatoid arthritis.Formule :C20H19F3N6O3S2Degré de pureté :98.11% - 99.18%Couleur et forme :SolidMasse moléculaire :512.53ST7612AA1
CAS :<p>ST7612AA1: potent, oral HDAC inhibitor; reactivates HIV-1 latency; shows antitumor effects; may study malaria.</p>Formule :C20H27N3O4SDegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :405.51Apricitabine
CAS :<p>Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-</p>Formule :C8H11N3O3SDegré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :229.26Werner syndrome RecQ helicase-IN-4
CAS :<p>Werner syndrome RecQ helicase-IN-4 is a WRN inhibitor with anticancer and anti-proliferative activity, used in colorectal and gastric cancer research.</p>Formule :C32H33F3N8O5Degré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :666.65DDD100097
CAS :<p>DDD100097 is a N-myristoyltransferase inhibitor with potential inhibitory effects on Trypanosoma brucei, which can be used to study neurological disorders.</p>Formule :C22H30Cl2F2N4O2SDegré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :523.47CM03
CAS :<p>CM03 is a cell-selective G-quadruplex ligand with anti-cancer activity, stabilizing G4 genes, useful in pancreatic cancer research.</p>Formule :C34H44N6O6Degré de pureté :98.65%Couleur et forme :SolidMasse moléculaire :632.75HHL-6
CAS :<p>HHL-6 is a c-Fos and BDNF protein expression modulator.</p>Formule :C19H26N2O3Couleur et forme :SolidMasse moléculaire :330.42Nitracrine
CAS :<p>Nitracrine: a 1-nitroacridine, hypoxia-selective, anti-tumor agent; inhibits RNA synthesis, binds DNA reversibly and forms covalent adducts.</p>Formule :C18H20N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.38
