Synthèse ADN/ARN
Les inhibiteurs de la synthèse de l'ADN et de l'ARN sont des composés qui interfèrent avec les processus de réplication et de transcription dans les cellules, empêchant ainsi la production de matériel génétique essentiel. Ces inhibiteurs peuvent cibler diverses enzymes et protéines impliquées dans la synthèse des acides nucléiques, ce qui en fait des outils précieux pour étudier les mécanismes de réplication, de transcription et de traduction. Ils sont également utilisés dans le développement de traitements contre les infections et le cancer. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de la synthèse de l'ADN/ARN pour soutenir vos recherches en biologie moléculaire, virologie et développement thérapeutique.
675 produits trouvés pour "Synthèse ADN/ARN".
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cis-Lomibuvir
CAS :cis-Lomibuvir (cis-VX-222) is a selective HCV NS5B RdRp inhibitor with a Kd of 17 nM and an EC50 of 5.2 nM, targeting thumb pocket 2.Formule :C25H35NO4SCouleur et forme :SolidMasse moléculaire :445.61SD49-7
CAS :SD49-7 is an inhibitor of histone lysine demethylase 4 (KDM4) with an IC50 of 0.19 µM.Formule :C18H14N2O3Degré de pureté :99.91%Couleur et forme :Yellow SolidMasse moléculaire :306.32Ref: TM-T67781
1mg57,00€5mg124,00€1mL*10mM (DMSO)141,00€10mg178,00€25mg359,00€50mg520,00€100mg745,00€500mg1.485,00€Antipain
CAS :Antipain, from Actinomycetes, blocks proteases and combats MNNG-induced genetic changes.Formule :C27H44N10O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :604.713Mulnitorsen
CAS :Mulnitorsen acts as an inhibitor of antisense non-coding mitochondrial RNA (ASncmtRNA) synthesis and serves as an antitumor agent [1].Formule :C172H217N74O82P17S17Couleur et forme :SolidMasse moléculaire :5704.66ddGTP trisodium
ddGTP trisodium, a ddNTP, inhibits or serves as a substrate for DNA polymerase α, halting DNA chain elongation.Formule :C10H13N5Na3O12P3Couleur et forme :SolidMasse moléculaire :557.13Phen-DC3 Trifluoromethanesulfonate
CAS :Phen-DC3 Trifluoromethanesulfonate targets G-quadruplexes and inhibits FANCJ/DinG helicases; IC50s: 65±6/50±10 nM.Formule :C36H26F6N6O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :848.75Nuclease S1
CAS :Nuclease S1 breaks down ssDNA and RNA, trims protruding ends of dsDNA.Couleur et forme :SolidCW-2
CW-2 is a PARP1 PROTAC degrader known for its potent antiproliferative effects against MDA-MB-231 cells (IC50 = 0.72 μM) and cisplatin-resistant cells (A549/CDDP: IC50 = 3.52 μM). It exhibits synergistic antitumor activity and enhanced membrane permeability. CW-2 exerts its antitumor effects by inducing DNA damage, disrupting DNA repair, and triggering mitochondrial-dependent apoptosis (apoptosis).Formule :C43H42Cl2FN11O10PtCouleur et forme :SolidMasse moléculaire :1156.21251T-2513
CAS :T-2513 inhibits topoisomerase I by covalently bonding to its DNA complex, blocking DNA replication and causing cell death.Formule :C25H27N3O5Couleur et forme :SolidMasse moléculaire :449.507DG1
DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressingFormule :C19H17N5O5SCouleur et forme :SolidMasse moléculaire :427.43Tubercidin 5'-triphosphate tetrasodium
Tubercidin5'-triphosphate (7-Deazaadenosine 5'-triphosphate) tetrasodium is a nucleoside analogue and serves as an active metabolite of Tubercidin.Couleur et forme :Odour Solidm7GpppAmpG
CAS :M7GpppAmpG is a trinucleotide 5′ cap analog, exhibiting capping efficiencies of 90% for the produced RNAs [1].Formule :C32H43N15O24P4Couleur et forme :SolidMasse moléculaire :1145.66CSN5-IN-2
CSN5-IN-2 (Compound 31) is a CSN5 inhibitor with an IC50 of 0.36 μM. It increases Cullin 1 neddylation levels in cancer cells and downregulates the expression of RAD51 and PD-L1. CSN5-IN-2 exhibits antitumor activity, which is enhanced when used in combination with Talazoparib.Couleur et forme :Odour SolidAV-153
CAS :AV-153, a 1,4-dihydropyridine, reduces DNA damage, stimulates repair, and has anti-cancer properties.Formule :C14H19NNaO6Couleur et forme :SolidMasse moléculaire :320.297Lorutengitide
CAS :Lorutengitide is a transcription-regulating peptide with antiproliferative activity.Formule :C30H50N8O12Couleur et forme :SolidMasse moléculaire :714.764LB80317
CAS :LB-80317, a DNA polymerase inhibitor, is used potentially for the potential treatment of hepatitis B virus infection.Formule :C10H14N5O5PCouleur et forme :SolidMasse moléculaire :315.22RNA splicing modulator 2
CAS :RNA splicing modulator 2 (compound 256) is a RNA splicing modulator [1] .Formule :C20H21N5OSCouleur et forme :SolidMasse moléculaire :379.48Ac-rC Phosphoramidite
CAS :Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.Formule :C47H64N5O9PSiDegré de pureté :98.29%Couleur et forme :White SolidMasse moléculaire :902.12'-(2-Nitrobenzyl)-ATP trisodium
2'-(2-Nitrobenzyl)-ATP trisodium is an rATP analogue that acts as a transcription terminator. It inhibits T7 RNA polymerase from continuing RNA chain extension.Formule :C17H18N6Na3O15P3Couleur et forme :SolidMasse moléculaire :707.97361N1-Methylpseudouridine-5′-triphosphate tetralithium
N1-Methylpseudouridine-5′-triphosphate tetralithium, also known as 1-Methylpseudouridine-5′-triphosphate tetralithium, is a nucleobase-modified nucleotide.Formule :C10H13Li4N2O15P3Couleur et forme :SolidMasse moléculaire :521.9RNA splicing modulator 1
CAS :RNA Splicing Modulator 1 (Compound 233) is a modulator of RNA splicing, exhibiting an AC50 value of less than 100 nM [1].Formule :C19H20N6OSCouleur et forme :SolidMasse moléculaire :380.4712R-LOX-IN-2
CAS :12R-LOX-IN-2 is a 12R-LOX inhibitor that inhibits the hyperproliferation of psoriatic cells and can be used in the study of psoriasis and other skin diseases.Formule :C19H13NODegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :271.31Guanine-13C5
Guanine-13C5 is the 13C-labeled form of Guanine (TMSM-1292).Couleur et forme :Odour SolidRNA splicing modulator 3
CAS :RNA Splicing Modulator 3 (Compound 236) is an effective RNA splicing modulator, exhibiting an AC50 value of less than 100 nM [1].Formule :C19H20N6OSCouleur et forme :SolidMasse moléculaire :380.47Deoxythymidine-5'-triphosphate sodium hydrate
dTTP sodium hydrate, a DNA synthesis component, is a nucleoside triphosphate.Formule :C10H17N2O14P3·xNa·xH2OCouleur et forme :SolidMasse moléculaire :C10H17N2O14P3.xNa.xH2ORAD51-IN-3
CAS :RAD51-IN-3 is a Rad51 inhibitor.Formule :C31H41N5O5S2Couleur et forme :SolidMasse moléculaire :627.82Carbazole
CAS :Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.Formule :C12H9NDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :167.211AO-022
AO-022 is a potent conformational inhibitor of TALDO1. It reduces the protein expression of vimentin and snail, exhibiting antiproliferative and antitumor activities. AO-022 holds potential for use in breast cancer research.Couleur et forme :Odour SolidKWR137
KWR137 is a WRN degrader with an IC50 of 8 nM. It exhibits significant antiproliferative activity against MSI-H cells, with a GI50 of 509 nM for SW48 cells and 824 μM for HCT116. Additionally, KWR137 demonstrates antitumor growth effects in xenograft mouse models. This compound is applicable for cancer research.Formule :C33H31ClF3N9O4Couleur et forme :SolidMasse moléculaire :710.105Pseudorabies virus-IN-1
Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.Formule :C27H23ClF2N4O2Couleur et forme :SolidMasse moléculaire :508.947ONX 0801 trisodium
CAS :ONX 0801 (BGC 945) trisodium is a targeted thymidylate synthase (TS) inhibitor specifically designed to act against tumors overexpressing the α-folate receptor.Formule :C32H30N5Na3O10Couleur et forme :SolidMasse moléculaire :713.58Ribonuclease T1
CAS :Rnase T1, an endonuclease, degrades single-stranded RNA to yield 3'-GMP oligonucleotides.Couleur et forme :SolidUCK2 Inhibitor-3
CAS :UCK2 Inhibitor-3 blocks UCK2 (IC50: 16.6μM) and DNA polymerases eta/kappa (IC50s: 56μM/16μM), aiding uridine salvage in certain cells.Formule :C19H13BrFN5O2SCouleur et forme :SolidMasse moléculaire :474.31SR15006
CAS :SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).Formule :C16H20ClN3O4SDegré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :385.873'-Deoxyuridine-5'-triphosphate trisodium
3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).Formule :C9H12N2Na3O14P3Couleur et forme :SolidMasse moléculaire :534.08WRN inhibitor 17
CAS :WRN inhibitor 17 (Compound 250) is an orally active inhibitor of Werner syndrome ATP-dependent helicase (WRN), specifically targeting the helicase domain activity of WRN. It holds potential for use in cancer research.Formule :C33H34F4N4O6SCouleur et forme :SolidMasse moléculaire :690.71Thymidine-D3
CAS :Thymidine-D3 is the deuterated form of Thymidine. It is a specific precursor of deoxyribonucleic acid (DNA) and functions as a cell synchronizing agent. Thymidine (TWP2911) acts as a DNA synthesis inhibitor, blocking cells at the G1/S boundary before DNA replication.Formule :C10H14N2O5Couleur et forme :SolidMasse moléculaire :245.25Uridine 5'-O-thiodiphosphate trisodium
Uridine 5'-O-thiodiphosphate (trisodium) (UDP-β-S (trisodium)) acts as an agonist for the purinergic P2Y6 receptor. This compound selectively induces the accumulation of inositol phosphate in 1321N1 cells expressing P2Y6 receptors, with an EC50 value of 28 nM. Additionally, it stimulates DNA synthesis in rat aortic smooth muscle cells.5-Iminodaunorubicin
CAS :5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.Formule :C27H30N2O9Couleur et forme :SolidMasse moléculaire :526.54Uridine-3'-monophosphate (sodium salt)
CAS :Uridine-3'-monophosphate, a nucleoside, aids ribothymidine synthesis and boosts learning/memory in studies.Formule :C9H11N2Na2O9PCouleur et forme :White SolidMasse moléculaire :368.15HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt
CAS :HOE 33187-O-CONH-PEG4-phenol-thiophenone-NHPh-COOEt inhibits pre-miR-21 RNA, potential for cancer research.Formule :C57H62N8O10SCouleur et forme :SolidMasse moléculaire :1051.21Uridine triphosphate-15N2 dilithium
Uridine triphosphate-15N2 dilithium is the 15N-labeled version of uridine triphosphate. Uridine triphosphate (UTP; Uridine 5'-triphosphate) is a nucleotide that regulates functions related to pancreatic endocrine and exocrine behavior, proliferation, channels, transporters, and intracellular signaling under both normal and pathological conditions.Couleur et forme :Odour SolidRNA polymerase II-IN-2
RNA Pol II-IN-2 (20iii) strongly inhibits Pol II (Ki=9.5 nM), is more toxic to CHO/HEK293 than α-amanitin.Formule :C41H58N10O12SCouleur et forme :SolidMasse moléculaire :915.02wrwycr-NH2 TFA
wrwycr-NH2 (TFA) is a peptide that exhibits cytotoxic properties against various cancer cells, inducing DNA damage and cell cycle arrest without causing endoplasmic reticulum stress. It possesses antitumor activity, and its efficacy is enhanced when used in combination with DNA-damaging agents.Couleur et forme :Odour SolidAdenine-13C5,15C5
Adenine-13C5,15C5 is the isotopically labeled form of adenine. This purine is one of the four nucleotide bases in DNA and is also a component of RNA. Adenine (T0064) is crucial in cellular respiration, the formation of ATP, coenzymes NAD and FAD, and protein synthesis.Couleur et forme :Odour SolidEmicoron
CAS :Importazole is an inhibitor of the transport receptor importin-β. It specifically inhibits importin-β likely by altering its interaction with RanGTP.Formule :C52H58N6O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :831.05ML-60218
CAS :ML-60218 inhibits RNA pol III in yeast/humans with IC50s of 32/27 μM; disrupts and prevents viroplasms.Formule :C19H15Cl2N3O2S2Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :452.38Ref: TM-T40661
1mg50,00€5mg108,00€1mL*10mM (DMSO)117,00€10mg168,00€25mg369,00€50mg575,00€100mg817,00€200mg1.099,00€FF-10502
CAS :FF-10502, a pyrimidine analog of Gemcitabine, inhibits DNA polymerases α/β, targeting dormant cancer cells.Formule :C9H12FN3O3SCouleur et forme :SolidMasse moléculaire :261.27CTP Synthetase-IN-1 Ammonium salt
CTP Synthetase-IN-1 Ammonium salt is a CTPS inhibitor with potential antibacterial, anti-inflammatory, and antitumor activity for the study of SARS-CoV-2 viral infectionsFormule :C20H22F3N7O3S2Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :529.5616,16-dimethyl Prostaglandin A1
CAS :16,16-dimethyl Prostaglandin A1 is a useful organic compound for research related to life sciences.Formule :C22H36O4Couleur et forme :SolidMasse moléculaire :364.526
