Synthèse ADN/ARN
Les inhibiteurs de la synthèse de l'ADN et de l'ARN sont des composés qui interfèrent avec les processus de réplication et de transcription dans les cellules, empêchant ainsi la production de matériel génétique essentiel. Ces inhibiteurs peuvent cibler diverses enzymes et protéines impliquées dans la synthèse des acides nucléiques, ce qui en fait des outils précieux pour étudier les mécanismes de réplication, de transcription et de traduction. Ils sont également utilisés dans le développement de traitements contre les infections et le cancer. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de la synthèse de l'ADN/ARN pour soutenir vos recherches en biologie moléculaire, virologie et développement thérapeutique.
708 produits trouvés pour "Synthèse ADN/ARN"
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2'-OMe-Ac-C Phosphoramidite
CAS :<p>2'-OMe-Ac-C Phosphoramidite, a modified phosphoramidite, is utilized in the synthesis of oligonucleotides.</p>Formule :C42H52N5O9PCouleur et forme :SolidMasse moléculaire :801.86LB80317
CAS :<p>LB-80317, a DNA polymerase inhibitor, is used potentially for the potential treatment of hepatitis B virus infection.</p>Formule :C10H14N5O5PCouleur et forme :SolidMasse moléculaire :315.22Phen-DC3 Trifluoromethanesulfonate
CAS :<p>Phen-DC3 Trifluoromethanesulfonate targets G-quadruplexes and inhibits FANCJ/DinG helicases; IC50s: 65±6/50±10 nM.</p>Formule :C36H26F6N6O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :848.75MRK-952
<p>MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.</p>Formule :C20H20ClF3N6Couleur et forme :SolidMasse moléculaire :436.861Pyrindamycin A
CAS :<p>Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.</p>Formule :C26H26ClN3O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :543.95GS-443902 trisodium
CAS :<p>GS-443902 trisodium, a strong RdRp blocker, inhibits RSV/HCV with IC50 of 1.1/5 μM and is Remdesivir's active form.</p>Formule :C12H16N5O13P3·xNaCouleur et forme :SolidGuanosine triphosphate
CAS :<p>Guanosine triphosphate (GTP), a native nucleotide, and its derivatives may serve as specific inhibitors against COVID-19 [1].</p>Formule :C10H16N5O14P3Couleur et forme :SolidMasse moléculaire :523.18RNA splicing modulator 2
CAS :<p>RNA splicing modulator 2 (compound 256) is a RNA splicing modulator [1] .</p>Formule :C20H21N5OSCouleur et forme :SolidMasse moléculaire :379.485-BrdUTP sodium salt
CAS :<p>5-BrdUTP sodium salt is a TdT substrate that can be used to label the DNA double-strand breaks.</p>Formule :C9H10BrN2Na4O14P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :634.977-TFA-ap-7-Deaza-ddG
CAS :<p>Compound 19d, a nucleotide derivative, is used to make thiotriphosphate dye terminators for DNA sequencing.</p>Formule :C16H16F3N5O4Couleur et forme :SolidMasse moléculaire :399.33Clofarabine-5'-triphosphate
CAS :<p>Clofarabine-5'-triphosphate is a metabolite of Clofarabine, produced via phosphorylation by deoxycytidine kinase (dCK). It exhibits cytotoxicity in cancer cells by inhibiting DNA synthesis and DNA repair.</p>Formule :C10H14ClFN5O12P3Couleur et forme :SolidMasse moléculaire :543.625'-O-DMT-Bz-rC
CAS :<p>5’-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Formule :C37H35N3O8Couleur et forme :SolidMasse moléculaire :649.69HDAC-IN-85
<p>HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.</p>Formule :C24H27FN4O5Couleur et forme :SolidMasse moléculaire :470.495'-O-DMT-PAC-dA
CAS :<p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>Formule :C39H37N5O7Couleur et forme :SolidMasse moléculaire :687.74CW-2
<p>CW-2 is a PARP1 PROTAC degrader known for its potent antiproliferative effects against MDA-MB-231 cells (IC50 = 0.72 μM) and cisplatin-resistant cells (A549/CDDP: IC50 = 3.52 μM). It exhibits synergistic antitumor activity and enhanced membrane permeability. CW-2 exerts its antitumor effects by inducing DNA damage, disrupting DNA repair, and triggering mitochondrial-dependent apoptosis (apoptosis).</p>Formule :C43H42Cl2FN11O10PtCouleur et forme :SolidMasse moléculaire :1156.21251Thailanstatin C
CAS :<p>Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.</p>Formule :C30H46ClNO9Couleur et forme :SolidMasse moléculaire :600.15Bz-rC Phosphoramidite
CAS :<p>Bz-rC Phosphoramidite is a phosphinamide monomer utilized for oligonucleotide synthesis.</p>Formule :C52H66N5O9PSiCouleur et forme :SolidMasse moléculaire :964.185wrwyar-NH2 TFA
<p>wrwyar-NH2 (TFA) serves as the control peptide for wrwycr-NH2.</p>Couleur et forme :Odour SolidAc-rC Phosphoramidite
CAS :<p>Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.</p>Formule :C47H64N5O9PSiDegré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :902.1Carbazole
CAS :<p>Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.</p>Formule :C12H9NDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :167.211KWR137
<p>KWR137 is a WRN degrader with an IC50 of 8 nM. It exhibits significant antiproliferative activity against MSI-H cells, with a GI50 of 509 nM for SW48 cells and 824 μM for HCT116. Additionally, KWR137 demonstrates antitumor growth effects in xenograft mouse models. This compound is applicable for cancer research.</p>Formule :C33H31ClF3N9O4Couleur et forme :SolidMasse moléculaire :710.1055'-O-DMT-rI
CAS :<p>5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].</p>Formule :C31H30N4O7Couleur et forme :SolidMasse moléculaire :570.5916,16-dimethyl Prostaglandin A1
CAS :<p>16,16-dimethyl Prostaglandin A1 is a useful organic compound for research related to life sciences.</p>Formule :C22H36O4Couleur et forme :SolidMasse moléculaire :364.526Diguanosine 5′-triphosphate
CAS :<p>Diguanosine 5′-triphosphate (Gp3G) is a kind of homodinucleotide from by GTP:GTP guanylyltransferase.</p>Formule :C20H27N10O18P3Couleur et forme :SolidMasse moléculaire :788.409Brr2-IN-2
<p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>Formule :C21H25FN4O2Couleur et forme :SolidMasse moléculaire :384.4513-TP
<p>13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.</p>Formule :C12H19F2N6O12P3Couleur et forme :SolidMasse moléculaire :570.23RNA polymerase II-IN-2
<p>RNA Pol II-IN-2 (20iii) strongly inhibits Pol II (Ki=9.5 nM), is more toxic to CHO/HEK293 than α-amanitin.</p>Formule :C41H58N10O12SCouleur et forme :SolidMasse moléculaire :915.025-Methylcytidine 5′-triphosphate
CAS :<p>5-Methylcytidine 5′-triphosphate (5-Methyl-CTP), a modified nucleoside triphosphate, enhances translational properties and stability while reducing innate</p>Formule :C10H18N3O14P3Couleur et forme :SolidMasse moléculaire :497.182'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
CAS :<p>dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.</p>Formule :C10H14N5Na2O8PCouleur et forme :SolidMasse moléculaire :409.202wrwycr-NH2 TFA
<p>wrwycr-NH2 (TFA) is a peptide that exhibits cytotoxic properties against various cancer cells, inducing DNA damage and cell cycle arrest without causing endoplasmic reticulum stress. It possesses antitumor activity, and its efficacy is enhanced when used in combination with DNA-damaging agents.</p>Couleur et forme :Odour SolidGuanosine 5'-triphosphate trisodium salt hydrate
CAS :<p>5'-GTP trisodium salt hydrate activates G proteins and is a precursor for DNA/RNA synthesis.</p>Formule :C10H18N5NaO15P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :564.185IBU-DC Phosphoramidite
CAS :<p>IBU-DC Phosphoramidite is used for synthesis of oligonucleotides.</p>Formule :C43H54N5O8PCouleur et forme :SolidMasse moléculaire :799.906Ribonuclease T1
CAS :<p>Rnase T1, an endonuclease, degrades single-stranded RNA to yield 3'-GMP oligonucleotides.</p>Couleur et forme :SolidUridine triphosphate 13C9,15N2 sodium
CAS :<p>Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.</p>Formule :C9H1415N2NaO15P3Couleur et forme :SolidMasse moléculaire :517.04Thio-ITP
CAS :<p>Thio-ITP (6-Thioinosine 5'-triphosphate) inhibits RNA polymerases I & II with Ki of 40.9 & 38.0 μM.</p>Formule :C10H15N4O13P3SCouleur et forme :SolidMasse moléculaire :524.23ONX 0801 trisodium
CAS :<p>ONX 0801 (BGC 945) trisodium is a targeted thymidylate synthase (TS) inhibitor specifically designed to act against tumors overexpressing the α-folate receptor.</p>Formule :C32H30N5Na3O10Couleur et forme :SolidMasse moléculaire :713.58(S)-DI-87
CAS :<p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor，reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>Formule :C23H30N6O3S2Degré de pureté :99.42%Couleur et forme :SoildMasse moléculaire :502.65Xanthosine-5'-Triphosphate
CAS :<p>Xanthosine-5'-Triphosphate (5'-XTP), a nucleotide derived from the deamination of purine bases, plays a crucial role in various biological processes.</p>Formule :C10H15N4O15P3Couleur et forme :SolidMasse moléculaire :524.164Pseudorabies virus-IN-1
<p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>Formule :C27H23ClF2N4O2Couleur et forme :SolidMasse moléculaire :508.9477-TFA-ap-7-Deaza-ddA
CAS :<p>Compound 19c is a nucleotide derivative for DNA sequencing dye terminators.</p>Formule :C16H16F3N5O3Couleur et forme :SolidMasse moléculaire :383.331SR15006
CAS :<p>SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).</p>Formule :C16H20ClN3O4SDegré de pureté :99.87%Couleur et forme :SoildMasse moléculaire :385.87N6-Methyladenine
CAS :<p>N6-Methyladenine (6-(Methylamino)Purine) is a modified purine commonly found in genomes of prokaryotes, protists, and plants.</p>Formule :C6H7N5Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :149.15EFdA-TP
CAS :<p>EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.</p>Formule :C12H15FN5O12P3Couleur et forme :SolidMasse moléculaire :533.1955'-O-DMT-rU
CAS :<p>5’-O-DMT-rU is a modified nucleoside and can be used to synthesize RNA.</p>Formule :C30H30N2O8Couleur et forme :SolidMasse moléculaire :546.575'-O-TBDMS-dG
CAS :<p>5’-O-TBDMS-dG is a modified nucleoside. 5’-O-DMT-2’-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.</p>Formule :C16H27N5O4SiCouleur et forme :SolidMasse moléculaire :381.505'-O-DMT-2'-O-TBDMS-Ac-rC
CAS :<p>5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Formule :C38H47N3O8SiCouleur et forme :SolidMasse moléculaire :701.892(+)-Glaucarubinone
<p>(+)-Glaucarubinone is a natural product that can be used as a reference standard.</p>Formule :C25H34O10Couleur et forme :SolidMasse moléculaire :494.537Cy5-dATP
<p>Cy5-dATP is a Cy5 -labeled dATP . Cy5-dATP can be incorporated into a DNA primer [1] [2] .</p>Formule :C47H58N7O19P3S2Couleur et forme :SolidMasse moléculaire :1182.055'-O-TBDMS-N2-ibu-dG
CAS :<p>5'-O-TBDMS-N2-ibu-dG: a nucleoside derivative with strong anti-BVDV activity, useful in lead compound synthesis.</p>Formule :C20H33N5O5SiCouleur et forme :SolidMasse moléculaire :451.59Clofarabine-5'-diphosphate trisodium
<p>Clofarabine-5'-diphosphatetrisodium (Clofarabine-DP trisodium) is the sodium salt form of Clofarabine-5'-diphosphate. As a metabolic product of Clofarabine, it results from phosphorylation by deoxycytidine kinase (dCK). Clofarabine-5'-diphosphate trisodium can undergo further phosphorylation to form Clofarabine-5'-triphosphate, demonstrating cytotoxicity in cancer cells by inhibiting DNA synthesis and repair.</p>Formule :C10H10ClFN5Na3O9P2Couleur et forme :SolidMasse moléculaire :529.58
