VHB
Les inhibiteurs du VHB sont des composés conçus pour cibler et inhiber diverses étapes du cycle de vie du virus de l'hépatite B (VHB). Ces inhibiteurs peuvent interférer avec la réplication virale, l'assemblage ou la libération, réduisant ainsi la charge virale et aidant à gérer les infections chroniques par le VHB. La recherche sur les inhibiteurs du VHB est cruciale pour le développement de thérapies antivirales efficaces pour prévenir les maladies du foie et le cancer associés au VHB. Chez CymitQuimica, nous proposons une gamme d'inhibiteurs du VHB pour soutenir vos recherches en virologie, développement de médicaments antiviraux et gestion des maladies infectieuses.
176 produits trouvés pour "VHB"
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BAY39-5493
CAS :<p>BAY39-5493 is a hepatitis B virus inhibitor and possess antiviral activity in vitro and in vivo.</p>Formule :C17H15ClFN3O2SCouleur et forme :SolidMasse moléculaire :379.84LP10
CAS :<p>LP10 is a reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1 and a Potent type II inhibitor of Trypanosoma cruzi CYP51.</p>Formule :C24H28N4O2Couleur et forme :SolidMasse moléculaire :404.5Rolicyprine
CAS :<p>Rolicyprine is an antidepressant.</p>Formule :C14H16N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :244.29trans-ccc_R08
CAS :<p>trans-ccc_R08: potent cccDNA inhibitor, IC50 0.08 µM, may help research HBV.</p>Formule :C22H19ClO6Couleur et forme :SolidMasse moléculaire :414.84HBV-IN-29
CAS :<p>HBV-IN-29 (ex8), a flavone derivative, inhibits cccDNA in HBV research.</p>Formule :C22H19ClO6Couleur et forme :SolidMasse moléculaire :414.84KKJ00626
CAS :<p>KKJ00626, an inhibitor of HBV virus, inhibits HBV replication in transfected Huh7 cells.</p>Formule :C7H8N4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :180.23HBV-IN-19
CAS :<p>HBV-IN19 suppresses HBV, cutting HBsAg output, useful for chronic HBV study.</p>Formule :C24H30N2O6Couleur et forme :SolidMasse moléculaire :442.5HBV-IN-25
CAS :<p>HBV-IN-25: oral HBV cccDNA reducer, anti-HBeAg, anti-HBV (IC50: 0.58/1.15 μM), soluble (>452 μg/mL), non-toxic.</p>Formule :C18H14ClNO4Couleur et forme :SolidMasse moléculaire :343.76Selgantolimod
CAS :<p>Selgantolimod is an effective and selective toll-like receptor 8 agonists for the treatment of the hepatitis B virus and human immunodeficiency virus infection.</p>Formule :C14H20FN5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :293.34Inarigivir
CAS :<p>Inarigivir (ORI-9020) is a dinucleotide that can significantly reduce liver HBV DNA.</p>Formule :C20H26N7O10PSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :587.5Alamifovir
CAS :<p>Alamifovir: HBV-specific antiviral, purine analog prodrug; active against wild-type/lamivudine-resistant HBV; inhibits DNA initiation/packaging.</p>Formule :C19H20F6N5O5PSCouleur et forme :SolidMasse moléculaire :575.42(5S,8R)-HBV-IN-10
CAS :<p>'(5S,8R)-HBV-IN-10 is an EC50 0.1-1 μM HBsAg inhibitor, isomer of compound 6 from patent WO2021204258A1.</p>Formule :C23H24FN7OCouleur et forme :SolidMasse moléculaire :433.48Helioxanthin derivative 5-4-2
CAS :<p>Helioxanthin derivative 5-4-2 （Helioxanthin 5-4-2） is an analogue of helioxanthin that shows anti-HBV activity in vitro and can be used to study HBV.</p>Formule :C20H13NO5Degré de pureté :99.91% - 99.92%Couleur et forme :SolidMasse moléculaire :347.32Fosclevudine alafenamide
CAS :<p>Fosclevudine alafenamide (Compound EIDD-02173) is an antiviral agent that acts against HBV (EC50: 1.71 μM).</p>Formule :C22H29FN3O9PCouleur et forme :SolidMasse moléculaire :529.45Taribavirin hydrochloride
CAS :<p>Taribavirin HCl: oral drug targeting HCV in liver, spares red blood cells, aims to reduce anemia risk.</p>Formule :C8H14ClN5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :279.68Helioxanthin 8-1
CAS :<p>Helioxanthin 8-1, an analogue of helioxanthin, exhibits significant in vitro anti-HBV/HCV/HSV-1/HIV activity with EC50 of >5/10/1.4/15 μM.</p>Formule :C20H12N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :376.32(-)-5′-Noraristeromycin
CAS :<p>(-)-5′-Noraristeromycin is an antiviral agent.</p>Formule :C10H13N5O3Couleur et forme :SolidMasse moléculaire :251.24RIG-1 modulator 1
CAS :<p>RIG-1 modulator 1 is useful for the treatment of viral infections including influenza virus, HBV, HCV and HIV.</p>Formule :C14H17N5OS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :335.45BA38017
CAS :<p>BA38017 is a potent assembly modulator of HBV core protein that inhibits the replication of HBV (EC50 = 0.20 μM) [1].</p>Formule :C15H11ClFNO3Couleur et forme :SolidMasse moléculaire :307.7BA-53038B
CAS :<p>BA-53038B is an HBV core protein allosteric modulator (CpAM), binding to the HAP pocket and modulating HBV capsid assembly in a distinct manner (EC50: 3.32 μM).</p>Formule :C14H16ClNOCouleur et forme :SolidMasse moléculaire :249.74Bay 41-4109 (less active enantiomer)
CAS :<p>Bay 41-4109 less active enantiomer shows less activity than Bay 41-4109. BAY 41-4109 is a potent HBV inhibitor (IC50: 53 nM).</p>Formule :C18H13ClF3N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :395.76Bentysrepinine
CAS :<p>Bentysrepinine, a novel anti-HBV agent, inhibits DNA-HBV and cccDNA activities for the treatment of hepatitis B virus (HBV)-infected hepatitis.</p>Formule :C29H35N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :489.61HBV-IN-10
CAS :<p>HBV-IN-10, an isomer of compound 6, inhibits HBsAg with EC50 between 0.1-1 μM (Patent WO2021204258A1).</p>Formule :C23H24FN7OCouleur et forme :SolidMasse moléculaire :433.48NVP018
CAS :<p>NVP018 (BC 556) inhibits HBV, HCV, HIV-1 replication, barely affects drug transporters, and resists HCV/HIV-1 resistance development.</p>Formule :C45H62FN5O11Couleur et forme :SolidMasse moléculaire :868DVR-01
CAS :<p>DVR-01 is an HBV capsid inhibitor and can be used in studies about the treatment of Hepatitis B virus (HBV) infection and related conditions.</p>Formule :C20H23ClN2O3SDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :406.93Clevudine triphosphate
CAS :<p>Clevudine triphosphate is a TTP analog that is able to inhibit protein priming independently of the deoxynucleoside triphosphate substrate.</p>Formule :C10H16FN2O14P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :500.16Lagociclovir
CAS :<p>Lagociclovir (MIV-210), a nucleoside analogue antiviral, treats HBV by inhibiting its replication in liver cancer cells.</p>Formule :C10H12FN5O3Degré de pureté :99.18% - 99.33%Couleur et forme :SolidMasse moléculaire :269.23Bay 41-4109
CAS :<p>BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV)(IC50 : 53 nM).</p>Formule :C18H13ClF3N3O2Couleur et forme :SolidMasse moléculaire :395.76HBV-IN-9
CAS :<p>HBV-IN-9 inhibits HBsAg (IC50: 10 nM) and HBV DNA replication (IC50: 0.15 nM) per WO2018001952A1.</p>Formule :C22H24FN7OCouleur et forme :SolidMasse moléculaire :421.47Taribavirin
CAS :<p>Taribavirin: oral drug targeting HCV in liver, spares RBCs to reduce risk of anemia.</p>Formule :C8H13N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :243.22HBV-IN-6
CAS :<p>HBV-IN-6 is a potent inhibitor of HBV (EC50: 44 nM).</p>Formule :C23H21ClFN3O5S2Couleur et forme :SolidMasse moléculaire :538.01Vidarabine phosphate
CAS :<p>Vidarabine phosphate is an adenosine monophosphate analog.</p>Formule :C10H14N5O7PDegré de pureté :99.75%Couleur et forme :White Crystalline PowderMasse moléculaire :347.22HBV-IN-32
CAS :<p>HBV-IN-32 is a strong cccDNA inhibitor with an IC50 of 0.14 µM against HBsAg, also halting cell growth.</p>Formule :C22H19ClO5SCouleur et forme :SolidMasse moléculaire :430.9L-Fd4A
CAS :<p>L-Fd4A (compound 36) is an adenine derivative with anti-HIV (EC50=1.5μM) and anti-HBV (EC50=1.7μM) effects, low cytotoxicity.</p>Formule :C10H10FN5O2Couleur et forme :SolidMasse moléculaire :251.22AB-506
CAS :<p>AB-506: Oral HBV replication blocker, targets core protein, hinders pgRNA encapsidation, for CHB study.</p>Formule :C21H18ClF2N5O3Couleur et forme :SolidMasse moléculaire :461.85cis-ccc_R08
CAS :<p>cis-ccc_R08 infection . cis-ccc_R08 is a cccDNA (covalently closed circular DNA) inhibitor .</p>Formule :C22H19ClO6Couleur et forme :SolidMasse moléculaire :414.84Besifovir PM
<p>Besifovir PM (LB80331 PM) is an analogue of Besifovir, a novel orally available acyclic nucleotide phosphonate for the treatment of chronic hepatitis B</p>Formule :C11H15N5ODegré de pureté :98.48% - 99.90%Couleur et forme :SoildMasse moléculaire :233.27Isothiafludine
CAS :<p>Isothiafludine is a HBV virus inhibitor that dramatically reduces the HBV DNA level in cells.</p>Formule :C18H18FN3OS2Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :375.48Bersacapavir
CAS :<p>Bersacapavir (JNJ-56136379) is an in vitro modulator of hepatitis B virus capsid assembly that inhibits HBV replication.</p>Formule :C16H14F4N4O3SDegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :418.37Tivicilovir
CAS :<p>Tivicilovir (AM188) is a hepatitis B virus inhibitor. tiviclovir is a guanine-related acyclic 2'-deoxyguanine analogue with anti-herpesvirus activity.</p>Formule :C9H13N5O3Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :239.23Pradefovir
CAS :<p>Pradefovir (Remofovir) is a prodrug for chronic HBV, converting to PMEA in the liver with a Km of 60 μM and clearance of 359 ml/min.</p>Formule :C17H19ClN5O4PDegré de pureté :97.50%Couleur et forme :SolidMasse moléculaire :423.79HBV-IN-8
CAS :<p>HBV-IN-6 is a potent inhibitor of HBV (EC50: 287.9 nM).</p>Formule :C21H25ClFN5O5S2Couleur et forme :SolidMasse moléculaire :546.04HBF-0259
CAS :HBF-0259 is an inhibitors of hepatitis B virus surface antigen (HBsAg) secretion with an EC50 of 11.3 μM and a CC50 value of >50 μM in HepG2.2.15 cells.Formule :C16H12Cl2FN5Degré de pureté :98.07% - 99.42%Couleur et forme :SolidMasse moléculaire :364.2HBV-IN-13
CAS :<p>HBV-IN-12 is a potent inhibitor of hepatitis B surface antigen (HBsAg).</p>Formule :C22H25NO7Couleur et forme :SolidMasse moléculaire :415.44HEC72702
CAS :<p>HEC72702: New HBV capsid inhibitor, from GLS4. No CYP1A2, CYP3A4, CYP2B6 induction at 10μM.</p>Formule :C24H26BrFN4O5SCouleur et forme :SolidMasse moléculaire :581.45HBV-IN-17
CAS :<p>HBV-IN-17 (compound 8) is a potent regulator of HBV capsid assembly (EC50: 511 nM).</p>Formule :C17H15F6N5O2Couleur et forme :SolidMasse moléculaire :435.32Oxynitidine
CAS :<p>Oxynitidine, an HBV inhibitor (ID50 = 30.8 µg/mL), effectively suppresses HBV DNA replication and may be utilized in viral infection research [1].</p>Formule :C21H17NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :363.36HBV-IN-41
CAS :<p>HBV-IN-41 (compound 45) is a potent, orally active inhibitor of Hepatitis B Virus (HBV), exhibiting an EC50 value of 0.027μM [1].</p>Formule :C18H19ClFN5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :407.83Emtricitabine triphosphate tetrasodium salt
CAS :<p>Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of the phosphorylated anabolite (-)-Emtricitabine triphosphate, an active nucleoside</p>Formule :C8H9FN3Na4O12P3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :575.11Tobevibart
CAS :<p>Tobevibart, an IgG1-lambda humanized monoclonal antibody targeting the hepatitis B virus (HBV) surface envelope protein, exhibits antiviral activity [1].</p>Degré de pureté :98%Couleur et forme :LiquidIR415
CAS :<p>IR415 selectively interacts with Hepatitis B virus X protein (HBx, Kd = 2 nM) and blocks HBV-mediated RNAi suppression, reverses the inhibitory effect of HBx</p>Formule :C13H14F2N4SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :296.34Valtorcitabine dihydrochloride
CAS :<p>Valtorcitabine dihydrochloride, a DNA polymerase inhibitor, is used potentially for the treatment of HBV infection.</p>Formule :C14H24Cl2N4O5Couleur et forme :SolidMasse moléculaire :399.27Besifovir Dipivoxil maleate
CAS :<p>Besifovir Dipivoxil maleate, an oral HBV prodrug (LB80380), suppresses HBV DNA in naive and lamivudine-resistant CHB cases.</p>Formule :C22H34N5O8PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :527.51HBV-IN-30
CAS :<p>HBV-IN-30, a flavone derivative, inhibits cccDNA in HBV research.</p>Formule :C22H18BrClO6Couleur et forme :SolidMasse moléculaire :493.73SHR5133
CAS :<p>SHR5133 is a potent, orally active regulator of HBV capsid assembly that reduces HBV DNA (EC50: 26.6 nM).</p>Formule :C19H18F4N6O2Couleur et forme :SolidMasse moléculaire :438.38AB-836
CAS :<p>AB-836, an orally active hepatitis B virus (HBV) capsid inhibitor, hampers viral replication by engaging with the HBV core protein.</p>Formule :C20H15F3N4O2Couleur et forme :SolidMasse moléculaire :400.35Lagociclovir valactate
CAS :<p>Lagociclovir valactate is a prodrug of Lagociclovir . Lagociclovir valactate is an orally active anti- HBV agent [1] .</p>Formule :C18H25FN6O6Couleur et forme :SolidMasse moléculaire :440.43Linvencorvir
CAS :<p>Linvencorvir is a hepatitis B virus (HBV) core protein variant modifier used to treat chronic HBV infection.</p>Formule :C29H35FN6O5SDegré de pureté :99.9% - 99.9%Couleur et forme :SolidMasse moléculaire :598.69Tenofovir amibufenamide
CAS :<p>Tenofovir amibufenamide (HS-10234) 是一种 Tenofovir 前药，是一种具有口服活性的抗病毒化合物。Tenofovir amibufenamide 对乙型肝炎病毒 (HBV)具有抑制作用，可用于慢性乙型肝炎 (CHB) 研究。</p>Formule :C22H31N6O5PDegré de pureté :99.19% - 99.87%Couleur et forme :SolidMasse moléculaire :490.49HBV-IN-24
<p>HBV-IN-24 inhibits HBV DNA, HBsAg, HBeAg (EC50: 0.6, 0.6, 4.6 nM), and has antiviral properties with neurotoxicity mitigation.</p>Formule :C23H27NO6Couleur et forme :SolidMasse moléculaire :413.46HBV/HDV-IN-3
CAS :<p>HBV/HDV-IN-3 (Compd 1) acts as a dual inhibitor for HBV and HDV, demonstrating an efficacy (EC 50) below 50 nM against HBV .</p>Formule :C28H27BrF3N5O3Couleur et forme :SolidMasse moléculaire :618.44SAG-524
CAS :<p>SAG-524 is a powerful oral small molecule that inhibits HBV viral replication. In HepG2.2.15 cells, SAG-524 reduced HBV-DNA and HbsAg levels in the supernatant with IC₅₀ values of 0.92 nM and 1.4 nM, respectively [1].</p>Formule :C30H32ClN5O4SCouleur et forme :SolidMasse moléculaire :594.12HBV/HDV-IN-2
CAS :<p>HBV/HDV-IN-2 (Compd 143) functions as an inhibitor for HBV, HDV, and PD-1/PD-L1, demonstrating an EC 50 of 35 nM in T cell activation.</p>Formule :C38H44ClN7O5Couleur et forme :SolidMasse moléculaire :714.25TLR8 agonist 4
<p>TLR8 agonist 4 inhibits wild-type and lamivudine/entecavir-resistant HBV; IC50: 0.15 μM and 0.10 μM.</p>Formule :C28H27N5O5SCouleur et forme :SolidMasse moléculaire :545.61HBV-IN-12
CAS :<p>HBV-IN-12: strong HBsAg & HBV DNA inhibitor; EC50 0.001-0.05 μM & 0.001-0.02 μM respectively. (WO2021204252A1)</p>Formule :C23H27NO8Couleur et forme :SolidMasse moléculaire :445.46HBV-IN-11
CAS :<p>HBV-IN-11 is a potent inhibitor of HBsAg secretion (EC50: 0.46 μM).</p>Formule :C21H24ClNO6Couleur et forme :SolidMasse moléculaire :421.87HBV-IN-18
<p>HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) (EC50: 2790 nM).</p>Formule :C17H15F6N5O2Couleur et forme :SolidMasse moléculaire :435.32HBV-IN-48
CAS :<p>HBV-IN-48, an HBV inhibitor, exhibits potent antiviral activity against HBV in HepDE19 cells, demonstrated by its EC 50 value of 0.005 μM. Additionally, it effectively reduces serum HBV DNA levels in mouse models of HBV infection.</p>Formule :C22H15F4N3O3Couleur et forme :SolidMasse moléculaire :445.37FNC-TP trisodium
<p>FNC-TP trisodium, active intracellular FNC form, inhibits NRTI, fights HIV, HBV, and HCV.</p>Formule :C9H11FN6Na3O13P3Couleur et forme :SolidMasse moléculaire :592.11HBV-IN-31
CAS :<p>HBV-IN-31: strong cccDNA inhibitor, anti-HBV, IC50=0.13 µM HBsAg, hampers cell growth.</p>Formule :C23H18ClNO6Couleur et forme :SolidMasse moléculaire :439.85HBV-IN-20
<p>HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).</p>Couleur et forme :SolidALG-000184
CAS :<p>ALG-000184, a prodrug of the potent HBV capsid assembly modulator ALG-001075, shows potential for use in HBV infection research.</p>Formule :C23H20FN4Na2O8PCouleur et forme :SolidMasse moléculaire :576.379HBV-IN-19 TFA
CAS :<p>HBV-IN19 TFA suppresses HBsAg, hampers HBV infection, and aids in HBV research.</p>Formule :C26H31F3N2O8Couleur et forme :SolidMasse moléculaire :556.53HBV-IN-34
CAS :<p>HBV-IN-34 (compound 17i) is a potent inhibitor of HBsAg production, demonstrating remarkable in vitro anti-HBV efficacy with EC50 values of 0.018 μM for HBV DNA</p>Formule :C21H19F2N7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :407.42HBV-IN-38
CAS :<p>HBV-IN-38 (Example 193), an HBV DNA inhibitor with an EC50 value of ≤100 nM, serves as a research tool for investigating viral infections [1].</p>Formule :C18H16F3N5O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :487.48Yhhu6669
CAS :<p>Yhhu6669 is an anti-HBV agent that suppresses viral DNA and replication by promoting DNA-free capsid assembly, effectively reducing HBV DNA and HBcAg levels in</p>Formule :C29H28ClFN6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :563.02
