AMPK
Les inhibiteurs de l'AMPK sont des composés qui ciblent et inhibent la Protéine Kinase Activée par l'AMP (AMPK), une enzyme jouant un rôle crucial dans l'homéostasie énergétique cellulaire. L'AMPK est activée en réponse à de faibles niveaux d'énergie dans les cellules et aide à réguler des processus tels que l'absorption du glucose, l'oxydation des acides gras et la biogenèse mitochondriale. Inhiber l'AMPK est important pour étudier son rôle dans les maladies métaboliques, le cancer et le vieillissement. Chez CymitQuimica, nous proposons une gamme d'inhibiteurs de l'AMPK pour soutenir vos recherches sur le métabolisme, l'oncologie et les maladies liées à l'âge.
161 produits trouvés pour "AMPK".
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6-Azuridine
CAS :6-Azauridine is a purine analog with antitumor effects, inhibiting DNA synthesis and inducing apoptosis in lymphatic cancers.Formule :C8H11N3O6Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :245.19Teneligliptin hydrobromide hydrate
CAS :Teneligliptin hydrobromide hydrate: potent, long-lasting DPP-4 inhibitor with ~1 nM IC50.Formule :C22H33BrN6O2SCouleur et forme :SolidMasse moléculaire :525.51Metformin-D6 hydrochloride
CAS :Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuteride of Metformin, which can be used to study Metformin metabolism in vivo.Formule :C4H12ClN5Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :171.66Ginkgolide C
CAS :Ginkgolide C (BN-52022), a natural product, can enhance the cardiac function of rats in the body.Formule :C20H24O11Degré de pureté :99.71% - 99.98%Couleur et forme :White PowderMasse moléculaire :440.40Platycodin D
CAS :Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA.Formule :C57H92O28Degré de pureté :99.2% - 99.65%Couleur et forme :White SolidMasse moléculaire :1225.32IMM-H007
CAS :IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expressionFormule :C22H23N5O8Degré de pureté :97.73%Couleur et forme :SolidMasse moléculaire :485.45Ref: TM-T9010
1mg38,00€5mg92,00€1mL*10mM (DMSO)124,00€10mg128,00€25mg215,00€50mg304,00€100mg411,00€200mg570,00€O-304
CAS :O-304 is a pan-activator of AMP-activated protein kinase (AMPK).Formule :C16H11Cl2N3O2SDegré de pureté :99.84% - ≥98%Couleur et forme :White SolidMasse moléculaire :380.25Ref: TM-T7362
1mg63,00€2mg92,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg205,00€25mg409,00€50mg605,00€100mg860,00€500mg1.728,00€Vaccarin
CAS :Vaccarin, a key flavonoid glycoside in Vaccariae semen, undergoes methylation, hydroxylation, glycosylation, and deglycosylation.Formule :C32H38O19Degré de pureté :99.16% - 99.97%Couleur et forme :SolidMasse moléculaire :726.63Demethyleneberberine
CAS :Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria eitherFormule :C19H18NO4Degré de pureté :98.08% - 99.18%Couleur et forme :SolidMasse moléculaire :324.35GSK621
CAS :GSK621 is a specific and potent AMPK activator.Formule :C26H20ClN3O5Degré de pureté :97.02% - 97.05%Couleur et forme :SolidMasse moléculaire :489.91Metformin
CAS :Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.Formule :C4H11N5Degré de pureté :99.77% - >99.99%Couleur et forme :SolidMasse moléculaire :129.16Ref: TM-T8526
1mL*10mM (DMSO)33,00€10mg44,00€25mg66,00€50mg93,00€100mg102,00€500mg250,00€2500mg414,00€DASA-58
CAS :DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator.Formule :C19H23N3O6S2Degré de pureté :96.96% - 99.28%Couleur et forme :SolidMasse moléculaire :453.53Trilobatin
CAS :Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentiallyFormule :C21H24O10Degré de pureté :97.16%Couleur et forme :SolidMasse moléculaire :436.41Ref: TM-T2S0731
1mg50,00€5mg99,00€1mL*10mM (DMSO)109,00€10mg141,00€25mg260,00€50mg385,00€100mg557,00€200mg790,00€ARN-3236
CAS :ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), (SIK2, SIK1 and SIK3 with IC50s of <1 nM, 21.63 nM and 6.63 nMFormule :C19H16N2O2SDegré de pureté :98.89% - 99.7%Couleur et forme :SolidMasse moléculaire :336.41Ref: TM-T5993
1mg57,00€5mg92,00€1mL*10mM (DMSO)142,00€10mg152,00€25mg250,00€50mg334,00€100mg512,00€200mg737,00€STO-609
CAS :STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.Formule :C19H10N2O3Degré de pureté :97.14% - 99.35%Couleur et forme :SolidMasse moléculaire :314.29Ref: TM-T3546
1mg39,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg120,00€25mg250,00€50mg400,00€100mg620,00€200mg873,00€WH-4-025
CAS :WH-4-025 is a Salt-inducible kinase (SIK) inhibitor.Formule :C39H38F3N7O5Degré de pureté :99.41%Couleur et forme :White SolidMasse moléculaire :741.76Ref: TM-T9219
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg130,00€25mg250,00€50mg396,00€100mg585,00€AMAROGENTIN
CAS :Amarogentin, extracted from Swertia/Gentiana roots, aids liver cancer prevention/treatment by affecting cell cycle and apoptosis.Formule :C29H30O13Degré de pureté :99.98% - ≥95%Couleur et forme :SolidMasse moléculaire :586.54Ref: TM-T5497
2mg37,00€5mg54,00€1mL*10mM (DMSO)71,00€10mg84,00€25mg152,00€50mg205,00€100mg289,00€200mg439,00€EB-3D
CAS :EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.Formule :C30H36Br2N4O2Degré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :644.4Ref: TM-T7955
1mg87,00€2mg114,00€5mg177,00€10mg260,00€1mL*10mM (DMSO)263,00€25mg447,00€50mg620,00€100mg875,00€200mg1.161,00€AMPK activator 2
CAS :AMPK activator 2, a chloroformin derivative, may boost cancer treatment by enhancing AMPK and inhibiting mTOR pathways, and cancer cell growth.Formule :C13H18F3N5Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :301.31BC1618
CAS :BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling.Formule :C24H24F3NO2Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :415.45Pyraclostrobin
CAS :Pyraclostrobin is one of the most heavily used fungicides that inhibits mitochondrial complex III of fungal and mammalian cells.Formule :C19H18ClN3O4Degré de pureté :99.89% - 99.96%Couleur et forme :Yellow SolidMasse moléculaire :387.82Buformin
CAS :Buformin, a biguanide oral antidiabetic, inhibits liver glucose production and improves insulin sensitivity.Formule :C6H15N5Couleur et forme :SolidMasse moléculaire :157.22WZ4003
CAS :WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively.Formule :C25H29ClN6O3Degré de pureté :99.65% - >99.99%Couleur et forme :SolidMasse moléculaire :496.99Ref: TM-T6291
5mg48,00€1mL*10mM (DMSO)50,00€10mg73,00€25mg111,00€50mg166,00€100mg241,00€200mg358,00€500mg590,00€MK-3903
CAS :MK-3903 is a potent and selective AMPK activator (EC50: 8 nM).Formule :C27H19ClN2O3Degré de pureté :98.63% - 99.75%Couleur et forme :SolidMasse moléculaire :454.9Ref: TM-T5187
1mg34,00€5mg75,00€1mL*10mM (DMSO)84,00€10mg114,00€25mg178,00€50mg334,00€100mg557,00€200mg790,00€IMT1
CAS :IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.Formule :C21H21NO4Degré de pureté :98.07% - 98.14%Couleur et forme :SolidMasse moléculaire :351.4Ref: TM-T8841
1mg77,00€5mg166,00€1mL*10mM (DMSO)178,00€10mg285,00€25mg533,00€50mg763,00€100mg1.054,00€Kahweol
CAS :Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaBFormule :C20H26O3Degré de pureté :99.26% - 99.86%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :314.42Dorsomorphin dihydrochloride
CAS :Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity onFormule :C24H25N5O·2HClDegré de pureté :97.74% - 99.89%Couleur et forme :SolidMasse moléculaire :472.41Ref: TM-T6146
2mg34,00€5mg49,00€1mL*10mM (DMSO)54,00€10mg66,00€25mg128,00€50mg222,00€100mg401,00€500mg888,00€COH-SR4
CAS :COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation.Formule :C13H8Cl4N2ODegré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :350.03Marein
CAS :Marein prevents PC12 cell damage by protecting mitochondria and activating AMPK, potentially countering diabetic encephalopathy.Formule :C21H22O11Degré de pureté :99.12% - 99.84%Couleur et forme :SolidMasse moléculaire :450.39Daphnetin
CAS :Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Formule :C9H6O4Degré de pureté :97.47% - 99.95%Couleur et forme :SolidMasse moléculaire :178.14Dorsomorphin
CAS :Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.Formule :C24H25N5ODegré de pureté :98% - 99.06%Couleur et forme :SolidMasse moléculaire :399.49Bempedoic acid
CAS :Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C.Formule :C19H36O5Degré de pureté :99.85% - 99.94%Couleur et forme :White SolidMasse moléculaire :344.49Ref: TM-T3625
2mg34,00€5mg50,00€1mL*10mM (DMSO)52,00€10mg70,00€25mg118,00€50mg207,00€100mg333,00€500mg797,00€Teneligliptin hydrobromide
CAS :Teneligliptin hydrobromide: potent, novel DPP-4 inhibitor; inhibits human/rat plasma DPP-4 with ~1 nM IC50.Formule :C22H30N6OSBrHDegré de pureté :97.83% - 99.92%Couleur et forme :SolidMasse moléculaire :628.86Flurbiprofen Axetil
CAS :Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.Formule :C19H19FO4Degré de pureté :97.58% - 98%Couleur et forme :SolidMasse moléculaire :330.35STF-118804
CAS :STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.Formule :C25H23N3O4SDegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :461.53SBI-0206965
CAS :SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.Formule :C21H21BrN4O5Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :489.32Gomisin J
CAS :Gomisin J is a natural product and have vasodilatory activity.Formule :C22H28O6Degré de pureté :99.59% - 99.60%Couleur et forme :SolidMasse moléculaire :388.45Ref: TM-T3904
1mg44,00€2mg62,00€1mL*10mM (DMSO)92,00€5mg113,00€10mg178,00€25mg313,00€50mg465,00€100mg662,00€GSK-690693
CAS :GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.Formule :C21H27N7O3Degré de pureté :98.07% - 99.77%Couleur et forme :SolidMasse moléculaire :425.48RSVA405
CAS :RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitorFormule :C17H20N4O2Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :312.37MOTS-c(Human) Acetate(1627580-64-6 free)
MOTS-c(Human) Acetate is a mitochondrial-derived peptide.Formule :C103H156N28O24S2Degré de pureté :99.93%Couleur et forme :White SolidMasse moléculaire :2234.64Nepodin
CAS :Nepodin exhibits antimalarial, anti-inflammatory, and antidiabetic effects by inhibiting COX and activating AMPK to stimulate GLUT4.Formule :C13H12O3Degré de pureté :97.9% - 99.12%Couleur et forme :SolidMasse moléculaire :216.23Ref: TM-TN1100
1mg54,00€2mg80,00€1mL*10mM (DMSO)114,00€5mg120,00€10mg192,00€25mg324,00€50mg480,00€100mg683,00€PKC-iota inhibitor 1
CAS :PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)Formule :C21H22N6ODegré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :374.44Ref: TM-T8764
1mg107,00€2mg152,00€5mg219,00€1mL*10mM (DMSO)226,00€10mg349,00€25mg583,00€50mg833,00€100mg1.134,00€500mg2.268,00€MRT67307 HCl (1190378-57-4(free base))
MRT67307 is a kinase inhibitor of TBK1, MARK1-4, IKKε, and NUAK1 (IC50: 19, 27-52, 160, and 230 nM, respectively).Formule :C26H37ClN6O2Degré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :501.07ON123300
CAS :ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).Formule :C24H27N7ODegré de pureté :99.53% - 99.7%Couleur et forme :SolidMasse moléculaire :429.52Metformin glycinate
CAS :Metformin glycinate activates AMPK, enhances insulin sensitivity, and reduces glucose absorption for better glycemic control.Formule :C6H16N6O2Couleur et forme :SolidMasse moléculaire :204.23[6]-Gingerol
CAS :[6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for tumors.Formule :C17H26O4Degré de pureté :98% - 99.95%Couleur et forme :White SolidMasse moléculaire :294.39Ref: TM-T3405
1mL*10mM (DMSO)38,00€5mg39,00€10mg52,00€1ml*10 (DMSO)67,00€25mg84,00€50mg111,00€20mg116,00€100mg163,00€200mg233,00€4g1.350,00€Palmitelaidic Acid
CAS :Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.Formule :C16H30O2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :254.41YKL-06-061
CAS :YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively.Formule :C30H37N7O2Degré de pureté :99.79% - 99.99%Couleur et forme :SolidMasse moléculaire :527.66Tizoxanide
CAS :Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.Formule :C10H7N3O4SDegré de pureté :98.89% - 99.28%Couleur et forme :SolidMasse moléculaire :265.25Kudinoside D
CAS :Kudinoside D exerts anti-adipogenic effects through modulation of adipogenic transcription factors via AMPK signaling pathway.Formule :C47H72O17Degré de pureté :99.66% - 99.92%Couleur et forme :SolidMasse moléculaire :909.06Ref: TM-TN1836
1mg119,00€5mg269,00€1mL*10mM (DMSO)324,00€10mg374,00€25mg577,00€50mg783,00€100mg1.054,00€200mg1.423,00€
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