PI3K
Les inhibiteurs de PI3K sont des composés qui bloquent l'activité des phosphoinositide 3-kinases (PI3Ks), une famille d'enzymes impliquées dans un large éventail de processus cellulaires, y compris la croissance, la prolifération, la survie et le métabolisme. La voie PI3K/Akt/mTOR est souvent dérégulée dans le cancer, ce qui fait de PI3K une cible clé pour la thérapie anticancéreuse. Les inhibiteurs de PI3K sont des outils essentiels pour étudier la transduction du signal, la biologie du cancer et le développement de thérapies ciblées. Chez CymitQuimica, nous proposons une variété d'inhibiteurs de PI3K pour soutenir vos recherches en signalisation cellulaire, en oncologie et en développement thérapeutique.
234 produits trouvés pour "PI3K"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Periplocin
CAS :Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.Formule :C36H56O13Degré de pureté :99.66% - 99.74%Couleur et forme :SolidMasse moléculaire :696.82Ref: TM-T5S1982
1mg35,00€5mg77,00€10mg106,00€25mg170,00€50mg253,00€100mg375,00€500mg892,00€1mL*10mM (DMSO)107,00€PIK-108
CAS :PIK-108 is an allosteric inhibitor of phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunits β and δ (PI3Kβ/δ).Formule :C22H24N2O3Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :364.44Ref: TM-T28416
1mg40,00€2mg57,00€5mg97,00€10mg156,00€25mg255,00€50mg368,00€100mg510,00€200mg700,00€1mL*10mM (DMSO)105,00€1-Deoxynojirimycin hydrochloride
CAS :1-Deoxynojirimycin hydrochloride (Moranoline) is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves.Formule :C6H14ClNO4Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :199.63AZD-7648
CAS :AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.Formule :C18H20N8O2Degré de pureté :99.03% - 99.85%Couleur et forme :SolidMasse moléculaire :380.4Ref: TM-T7122
1mg40,00€5mg88,00€10mg119,00€25mg187,00€50mg311,00€100mg472,00€200mg687,00€1mL*10mM (DMSO)87,00€Omipalisib
CAS :Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.Formule :C25H17F2N5O3SDegré de pureté :98% - 99.8%Couleur et forme :SolidMasse moléculaire :505.5Desmethylglycitein
CAS :Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which hasFormule :C15H10O5Degré de pureté :97.93%Couleur et forme :SolidMasse moléculaire :270.24PI-103
CAS :PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).Formule :C19H16N4O3Degré de pureté :97.79% - 99.3%Couleur et forme :SolidMasse moléculaire :348.36GNE-493
CAS :GNE-493 is potent, selective, and orally available PI3K and mTOR inhibitor with potential anticancer activity.IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM forFormule :C17H20N6O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :372.44GDC0084
CAS :<p>GDC0084 (RG7666) is a PI3K inhibitor with potential antineoplastic activity.</p>Formule :C18H22N8O2Degré de pureté :99.72% - 99.87%Couleur et forme :SolidMasse moléculaire :382.42Taurolithocholic acid sodium salt
CAS :Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, butFormule :C26H44NNaO5SDegré de pureté :99.79% - 99.93%Couleur et forme :SolidMasse moléculaire :505.69ZSTK474
CAS :<p>PI3K Inhibitor ZSTK474 is an orally available, s-triazine derivative, ATP-competitive phosphatidylinositol 3-kinase (PI3K) inhibitor with potential</p>Formule :C19H21F2N7O2Degré de pureté :98.29% - 99.95%Couleur et forme :White PowderMasse moléculaire :417.413-Methyladenine
CAS :3-Methyladenine (3-MA) is a PI3K inhibitor that selectively inhibits class IB PI3Kγ (IC50=60 μM) and class III VPS34 (IC50=25 μM).Formule :C6H7N5Degré de pureté :98% - 99.51%Couleur et forme :SolidMasse moléculaire :149.15Flavanomarein
CAS :Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.Formule :C21H22O11Degré de pureté :98.63% - 99.54%Couleur et forme :SolidMasse moléculaire :450.39Hederacolchiside A1
CAS :Hederacolchiside A1 exhibits anti-leishmanial and anticancer activities by disrupting cell membranes and inducing apoptosis via the PI3K/Akt/mTOR pathway.Formule :C47H76O16Degré de pureté :98.76% - 99.92%Couleur et forme :SolidMasse moléculaire :897.1Ref: TM-T2P2806
1mg48,00€5mg120,00€10mg170,00€25mg283,00€50mg430,00€100mg620,00€200mg870,00€1mL*10mM (DMSO)170,00€TASP0415914
CAS :TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). TFormule :C13H17N5O3SDegré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :323.37Ref: TM-T7879
1mg55,00€5mg117,00€10mg187,00€25mg315,00€50mg449,00€100mg620,00€200mg835,00€1mL*10mM (DMSO)134,00€Fimepinostat
CAS :Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both PI3K class I and pan-HDAC enzymes, with potential antineoplastic activity.Formule :C23H24N8O4SDegré de pureté :98.27% - 99.87%Couleur et forme :SolidMasse moléculaire :508.55Ref: TM-T2078
2mg47,00€5mg70,00€10mg97,00€25mg175,00€50mg311,00€100mg512,00€500mg1.093,00€1mL*10mM (DMSO)79,00€Idelalisib
CAS :Idelalisib (GS-1101) is a small molecule inhibitor of the PI3K catalytic subunit p110δ (IC50: 2.5 nM).Formule :C22H18FN7ODegré de pureté :98% - 99.39%Couleur et forme :SolidMasse moléculaire :415.42Ref: TM-T1894
5mg35,00€10mg50,00€25mg74,00€50mg93,00€100mg108,00€200mg140,00€500mg225,00€1mL*10mM (DMSO)52,00€BGT226
CAS :BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.Formule :C28H25F3N6O2Degré de pureté :95.74% - 99.78%Couleur et forme :SolidMasse moléculaire :534.53Ref: TM-T6072L
1mg49,00€2mg65,00€5mg97,00€10mg156,00€25mg311,00€50mg512,00€100mg777,00€1mL*10mM (DMSO)113,00€Bimiralisib
CAS :Bimiralisib (PI3K-IN-2) is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activity.Formule :C17H20F3N7O2Degré de pureté :97.58% - 98.92%Couleur et forme :SolidMasse moléculaire :411.38Wortmannin
CAS :Wortmannin (SL-2052) is a PI3K inhibitor (IC50=3 nM) that is covalent and irreversible.Formule :C23H24O8Degré de pureté :95.84% - 99.77%Couleur et forme :White SolidMasse moléculaire :428.43Ref: TM-T6283
1mg38,00€2mg49,00€5mg80,00€10mg119,00€25mg235,00€50mg406,00€100mg602,00€1mL*10mM (DMSO)88,00€
