Oligosaccharides

<p>Potential prebiotic oligosaccharides made from agar by enzymatic hydrolysis</p>

<p>Lactose is the principal sugar in human and most other mammalian milks, ( 4-O-(β-d-galactopyranosyl)-d-glucopyranose) (Collins, 2006). Lactose undergoes mutarotation; it is a reducing sugar and is significantly less soluble in water than sucrose. Lactose is much less sweet than sucrose (at ~1% about 0.15 (sucrose=1). The enzyme lactase (β-galactosidase), which is present in the small intestine, catalyzes hydrolysis of lactose to form glucose and galactose. Anhydrous lactose is an excipient, filler, diluent, and bulking agent in a wide variety of pharmaceutical tablets, capsules, powders and other preparations. Lactose also has applications as a nutrient and multi-functional ingredient in infant formulae, geriatric, dietetic and health foods (Linko, 1982).</p>

<p>This mixture contains some of the neutral and sialylated oligosaccharides found in human meconium.</p>

<p>Sucrose acetoisobutyrate (SAIB) is an emulsifier and is compatible with a wide variety of polymers, resins, plasticisers, oils and waxes - where it is used in surface coatings. Food applications have been developed for this compound and it has an E number (E444). It is recognized as a safe food additive in cocktail mixers, beer, malt beverages, or wine coolers and is a potential replacement for brominated vegetable oil.</p>

<p>GloboH-pentanyl backbone for incorporation onto peptide or conjugated to protein</p>

<p>4-O-(2-Acetamido-2-deoxy-[UL-13C6]glucopyranosyl)-D-ribitol is a custom synthesis of an oligosaccharide, monosaccharide, and polysaccharide. It is a high purity and CAS No. custom synthesis with a high degree of modification. This product has been synthesized by methylation and glycosylation for use in the study of the structure and function of complex carbohydrates. The fluorination was done to the saccharide to give it the desired properties for use in various applications.</p>

<p>Tri-mannuronic acid sodium salt (b-1,4-linked sodium mannuronotriose) is one of a number of oligosaccharides obtained from alginate which is a polysaccharide in brown seaweeds containing: blocks of repeating mannuronic acid sequences (M-M-M-M etc), repeating guluronic acid sequences (G-G-G-G etc), and alternating M-G-M-G sequences.Oligosaccharides can be released using several methods (Lua, 2015; Yanga, 2004) and claims have been published that mannuronic acid oligosaccharides for example, can be effective in the prophylaxis and treatment of Alzheimer's disease, or for the prophylaxis and treatment of diabetes (USP 8835403B2, 2014).</p>

<p>Useful oligosaccharide-lipid conjugate for raising antibodies.</p>

<p>Cellobionic acid is produced by oxidative enzymes working on cellulose.  These compounds have found application in cosmetic antiaging formulations, moisturizers, and peels, and in treatment products to improve hyperpigmentation and acne. The bionic acids such as cellobionic acid offer the benefits of α-hydroxyacids without irritation. They also provide additional antioxidant/chelation, barrier strengthening, and moisturizing effects.</p>

<p>Please enquire for more information about D-Maltose monohydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2,3,6-Tri-O-acetyl-4-O-(2,3,6-tri-O-acetyl-4-O-[(2,3,4,6-tetra-O-acetyl bDgalactopyranosyl)]bDglucopyranosyl)-aDglucopyranosyldimethyl bromide is a synthetic sugar that is used as a building block for the synthesis of glycosides. This monosaccharide has been modified using click chemistry to obtain a methylated form that can be used in the synthesis of oligosaccharides and polysaccharides. It is also used to produce an acetal derivative that can be used in the synthesis of glycosidic linkages.</p>

<p>Chondroitin disaccharide 6S sodium salt is a synthetic, fluorinated, oligosaccharide that has been custom synthesized and glycosylated. It is a sugar-based compound with a high purity and excellent solubility in water. It was synthesized by click modification of the sugar monomer with an amine group at the reducing end. The chondroitin disaccharide 6S sodium salt was further modified with methylation to yield a product with a higher purity.</p>

<p>Hyaluronate fluorescein is a polymer of hyaluronic acid that has been modified with fluorescein. It is synthesized by the methylation and saccharide coupling of an oligosaccharide, followed by Click modification and the addition of a fluorescent dye. Hyaluronate fluorescein has a molecular weight of 2500kDa. It is highly purified and can be custom-synthesized to suit specific needs.</p>

<p>4-Glucopyranosylmannose is a disaccharide compound, which is a synthetic carbohydrate derived from the enzymatic or chemical glycosylation processes. It consists of glucose and mannose units linked through a glycosidic bond. The compound is sourced through advanced synthetic methodologies involving specific glycosyltransferases or chemical catalysts that facilitate the precise attachment of these sugar moieties.</p>

<p>Maltotetraose-APD-HSA is a complex carbohydrate with a high purity. Maltotetraose-APD-HSA is a synthetic oligosaccharide that has been modified by glycosylation, methylation, and fluorination. It is an alpha 1,4 linked maltotetraose that has been conjugated to HSA. Maltotetraose-APD-HSA has the CAS number 113789-04-8 and its molecular weight is 495.7 Da. Maltotetraose-APD-HSA can be found in the monosaccharides saccharide and carbohydrate categories.</p>

<p>α-6⁴-6³-Di-galactosyl-mannopentaose is a specialized oligosaccharide, which is a type of complex carbohydrate. This compound is derived from natural plant sources and its structure comprises a mannopentaose core linked with two galactose units. The mode of action involves specific interactions with gut microbiota, where it selectively enriches beneficial bacterial populations, such as Bifidobacteria and Lactobacilli. These interactions occur by serving as a fermentation substrate, promoting the growth of microbes that confer beneficial effects on host health.</p>

<p>NGA2 Glycan, 2-AB labelled is a complex carbohydrate that is custom synthesized for research purposes. It is a high purity, high quality product that has been fluorinated and glycosylated. NGA2 Glycan, 2-AB labelled is used in the synthesis of oligosaccharides and polysaccharides. This product can be used for glycosylation, methylation and click modification.</p>

<p>Please enquire for more information about 1,5-α-L-Arabinooctaose including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Globotriose conjugated to HSA via an aminophenylethyl spacer (APE)</p>

<p>Blood group B trisacchharide-APE-HSA is a synthetic carbohydrate that inhibits the synthesis of complex carbohydrates. The methylation of saccharides and polysaccharides can be accomplished by the addition of an amine to the 3′ hydroxyl group. In this reaction, the sugar is attached to a protein carrier (e.g., human serum albumin) via an amide bond, which prevents its degradation by proteases in the body. The modification of saccharides and polysaccharides is also accomplished through click chemistry, which is based on copper catalysis. This process involves attaching two functional groups through a copper-mediated reaction, forming a new carbon-carbon bond. Modification of saccharides and oligosaccharides can be accomplished using either chemical or enzymatic methods. Sugar modification can be achieved using high purity enzymes that have been custom synthesized for specific purposes (e.g., glycosylation). Carbohydrate modification can</p>

<p>A modified heparin disaccharide</p>

<p>4-O-Acetyl-3,6-di-O-(2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl)-1,2-ethyledine (CAS No. 230953-17) is a carbohydrate that has been modified with acetyl groups at the 3 and 6 positions of the monosaccharide unit. This modification is a complex carbohydrate that is made up of oligosaccharides and polysaccharides. The modification causes changes in the chemical properties of the carbohydrate compared to natural saccharides. 4-O-(2,3,4,6) tetra O acetyl a D mannopyranosyl 1 2 ethyledine b D mannopyranose has been used in synthesis of custom sugars for medical applications. It has also shown anti inflammatory activities against Mycobacterium tuberculosis and Mycobacterium avium complex</p>

<p>Lacto-N-fucopentaose II-APD-HSA is a complex carbohydrate that has been chemically modified to include a fucose sugar. Lacto-N-fucopentaose II-APD-HSA is synthesized by the click reaction and then modified with the addition of an acetyl group. The product is then methylated and purified by HPLC. Lacto-N-fucopentaose II-APD-HSA can be used in a wide range of applications, including as a component in glycosylation reactions or as an adjuvant for fluorescence labelling.</p>

<p>1,5-α-L-Arabinohexaose is a carbohydrate. It is a nonreducing sugar that can be found in plants. 1,5-α-L-Arabinohexaose has an optimum pH of 5 and an ethanol concentration of 0.02%. The enzyme form of 1,5-α-L-Arabinohexaose is α-(1→6)-glycosidase. This enzyme hydrolyzes the α-(1→6) glycosidic bond between two glucose residues in a polysaccharide chain to produce β-(1→4) bonds. It also hydrolyzes the β-(1→4) glycosidic bond between two galactose residues to produce β-(1→2) bonds and oxidizes the terminal carbon atom to produce aldehyde products.<br>A structural analysis of this carbohydrate was conducted using marine microorganisms and it was found that they contain galacturonic acid and sugar residues</p>

<p>Monofucosyl, monosialyllacto-N-neohexaose-APD-HSA is a complex carbohydrate that is synthesized through the enzymatic polymerization of glucose. This synthetic oligosaccharide is composed of a single monosaccharide, fucose, and two sialic acid residues. Monofucosyl, monosialyllacto-N-neohexaose-APD-HSA can be used in the synthesis of various glycoconjugates such as glycoproteins, glycolipids, or proteoglycans. The chemical modification of this sugar molecule can also be performed to produce a variety of products with different properties.</p>