Composés polycycliques

<p>Please enquire for more information about 1-(2-Methoxyethyl)-1H-indole-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>7-Methylquinoline is an organic compound that can be used to synthesize antimalarial drugs. It is a quinoline derivative with a methyl group at the 7th position. The structure of 7-methylquinoline contains a nitrogen atom and hydrogen atoms, which are bonded to fluorine, chlorine, and bromine atoms. This molecule has been shown to be stable in the presence of Friedel-Crafts catalysts and chloride ions. The reaction mechanism for 7-methylquinoline is intramolecular hydrogen transfer from the chloroform molecule to the quinoline ring system. The formation rate for this compound is slow because it requires two steps: nucleophilic substitution and electrophilic addition reactions.</p>

<p>4,7-Dihydroxy-1,10-phenanthroline is an organometallic compound that has been shown to inhibit the growth of tumour cells. It is a protonated molecule and can be classified as a reactive intermediate. The reaction mechanism for this intermediate is nucleophilic attack by the hydroxy group on the carbon atom adjacent to the aromatic ring. This results in the formation of a cationic intermediate, which undergoes protonation to form the final product. 4,7-Dihydroxy-1,10-phenanthroline has been found to have anti-tumor effects against l1210 murine leukemia cell lines.</p>

<p>Please enquire for more information about 4-Chloroquinoline-6-carboxylicacid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>cis-Isokhellactone is a bioactive compound that belongs to the class of sesquiterpene lactones, which is isolated from plants in the genus Khella. With a well-characterized molecular structure, this compound exhibits significant binding affinity for cellular targets that are crucial in the regulation of cell proliferation and apoptosis. The mode of action involves the modulation of signaling pathways involved in cell cycle regulation and the induction of apoptosis in neoplastic cells.</p>

<p>4-Hydroxy-7-methoxyquinoline is an anti-malarial drug that belongs to the class of trimethyl, trifluoromethyl group. It is a cyclic compound and its synthesis starts with cyclization of the methyl derivative, which forms a ring. This product is used in clinical practice as an inhibitor of malarial protozoa and has been shown to have mechanistic effects on the cytochrome bc1 complex containing red blood cells. 4-Hydroxy-7-methoxyquinoline also inhibits the growth of bacteria by binding to the enzyme methionine synthase, which is involved in the biosynthesis of methionine from homocysteine. The product also has an inhibitory effect on DNA synthesis and protein synthesis.</p>

<p>Please enquire for more information about 1-(Ethyl-3-carboxypropyl)-3,7-dimethylxanthine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Pranferol is a phytochemical compound, which is derived from natural plant sources. It possesses unique immunomodulatory properties, affecting cellular pathways that regulate immune responses. The bioactive components in Pranferol interact with specific receptors on immune cells, modulating signaling cascades and gene expression to enhance or suppress specific immune functions depending on the physiological context.</p>

<p>Please enquire for more information about (3R)-1-Azabicyclo[2.2.2]oct-3-yl N-[2-(2-benzoylphenyl)ethyl]carbamate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2,3-Dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 9-[(5-Amino-1,3,4-thiadiazol-2-yl)methyl]-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Trans-Khellactone is a naturally occurring lactone derivative, which is isolated from plants of the Apiaceae family. This compound exhibits a variety of biological functions due to its unique chemical structure, which includes a dihydropyran ring. Trans-Khellactone's mode of action involves interacting with various cellular pathways, potentially modulating enzyme activity, receptor binding, and influencing signal transduction processes.</p>

<p>Please enquire for more information about 2-[2-(1H-Indol-3-yl)ethyl]-1,3-dioxoisoindoline-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about tert-Butyl 4,7-diazaspiro[2.5]octane-7-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Bromoindazole is an antibacterial agent that binds to the protonated form of the staphylococcal enzyme methicillin-resistant penicillinase (MRP) and prevents the enzyme from participating in the synthesis of cell wall precursors. The molecular modeling studies of 4-bromoindazole have shown that it can bind to pyogenes, a bacterium that causes streptococcal pharyngitis, by hydrogen bonding between its amide group and pyogenes' carboxylic acid group. 4-Bromoindazole also has anticancer activity against cancer cells with v600e mutation. It has been shown that 4-bromoindazole inhibits cancer cell proliferation by binding to the oxacillin site on DNA gyrase and topoisomerase IV, leading to DNA damage and apoptosis.</p>

<p>Imidazole is a highly polar aromatic compound with two annular nitrogen atoms. Imidazole is widely used in the affinity purification of proteins with polyhistidine tags (His-Tag). In the protein purification process, imidazole is used for the elution of His-Tag-fused recombinant proteins from a metal-immobilised resins. In the elution buffers, imidazole is typically used in the 50 – 500 mM concentration range (Bornhorst and Falke, 2000).</p>

<p>Please enquire for more information about 1-Benzyl-3-[3-(diethylamino)propoxy]-1H-indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 7-Azaspiro[4.5]decane including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4,4'-Dithio-2,2'-bipyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>3-Acetyl-5-hydroxymethyl-7-hydroxycoumarin is a synthetic coumarin derivative, which is a class of organic compounds often found in natural products. These compounds are derived from plant sources and are known for their significant biochemical effects and aromatic properties. The mode of action of 3-Acetyl-5-hydroxymethyl-7-hydroxycoumarin involves interactions at the molecular level, where it can exhibit various biological activities, such as antioxidant and antimicrobial effects. Due to the hydroxyl and acetyl functional groups present, it can participate in redox reactions and binding interactions, affecting biochemical pathways.</p>

<p>Prenyletin methyl ether is a flavonoid compound, which is a naturally occurring polyphenolic molecule sourced primarily from specific plant species. This compound exerts its effects through a variety of biochemical interactions, notably influencing cellular signaling pathways, including antioxidative and anti-inflammatory processes.</p>

<p>2-Hydroxyquinoline-4-carboxylic acid is a carboxylate that is structurally classified as a multidrug. It has been shown to inhibit bacterial efflux pumps and target enzymes, such as cancer cells and multidrug resistant bacteria. 2-Hydroxyquinoline-4-carboxylic acid also has potent antibacterial activity against Streptococcus faecalis, an opportunistic pathogen that causes infections in the urinary tract and on skin wounds. The fluorescence properties of this compound can be used for fluorescent labeling of biomolecules or for sensing applications.</p>

<p>Ostruthin is a naturally occurring coumarin derivative, which is isolated from plants such as *Peucedanum ostruthium* and other species within the Apiaceae family. It functions as an enzyme inhibitor, acting primarily through its interference with various cellular processes, including the inhibition of specific enzyme pathways that contribute to its bioactivity. Ostruthin exhibits a range of biological activities, making it of significant interest in pharmacological research.</p>

<p>Please enquire for more information about 8-Ethyl-1,3,4,9-tetrahydro-1-(1-methylethyl)pyrano[3,4-b]indole-1-acetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 6-Bromo-4-nitro-1H-indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Pangelin is a novel biochemical agent, which is meticulously derived from a unique microbial source with advanced bioconversion techniques. This product functions primarily through a targeted enzymatic mechanism that modulates specific biochemical pathways, ensuring high specificity and efficacy in its action. The enzymatic process engages with targeted substrates to yield predictable and controlled outcomes, making it a potentially valuable tool in biochemical research and applications.</p>

<p>Neobyakangelicol is a phytochemical compound, which is a natural product derived from various plant species. Its source is predominantly the roots of certain medicinal plants that are known for their array of bioactive constituents. The mode of action of Neobyakangelicol primarily involves interacting with specific biochemical pathways, potentially including modulation of enzyme activity or receptor binding, which could result in diverse pharmacological effects.</p>

<p>7-(Diethylamino)-3-(1-methyl-2-benzimidazolyl)coumarin is a fluorescent dye, which is synthesized through chemical derivatization of coumarin compounds. Originating from coumarin, a naturally occurring compound in plants, this dye is particularly noted for its ability to fluoresce under UV and visible light.</p>

<p>5-Nitrosoquinolin-8-ol is a chemical inhibitor that can be used in the study of enzyme function. It reacts with the active site of the enzymes and prevents them from carrying out their normal functions. 5-Nitrosoquinolin-8-ol has been shown to inhibit the growth of cancer cells and to have antiinflammatory properties. 5-Nitrosoquinolin-8-ol has been shown to bind to sephadex G-100 and potassium dichromate, which are both types of ion exchangers. The redox potential for this compound is -0.84 V. This means it will not react easily with other compounds, which makes it a good candidate for use as an inhibitor in biochemical studies. The nitrogen atoms in this compound are reactive, which means they can form covalent bonds with other molecules in a reaction called nitrosation. Structural biology is a branch of science that deals with studying the three dimensional structure of biological mac</p>

<p>Please enquire for more information about Methyl 4-methoxy-1-methyl-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Selinidin is a phytochemical compound, which is derived from the natural source of the Brunsvigia bosmaniae plant. As a bioactive constituent of this plant, it is characterized by its unique structure and chemical properties, enabling it to interact with a variety of cellular targets, primarily through modulation of inflammatory pathways. The mode of action of Selinidin involves the inhibition of pro-inflammatory cytokines and mediators, thereby reducing inflammation and oxidative stress at the cellular level.</p>

<p>1,4-Diazabicyclo[2.2.2]octane is an organic compound that belongs to the group of coordination compounds and has antimicrobial activity. It is a colorless solid with a melting point of -117°C and a boiling point of 245°C. The molecular geometry is planar, which means that all bonds are linear. The compound can be found in water vapor or as colloidal gold sols in reaction with water vapor. It can also be obtained by reacting triethylenediamine with hydrochloric acid at 100°C under vacuum conditions. 1,4-Diazabicyclo[2.2.2]octane has been shown to have antibiotic properties and is able to inhibit the growth of bacteria through coordination geometry and phase transition temperature effects on the bacterial cell membrane.</p>

<p>1,3,7,8-Tetramethylpurine-2,6-dione is a synthetic compound that has been identified as a possible dietary supplement. It is found in human urine and has been shown to inhibit the growth of fungi such as tebuconazole. The compound has been used as a substitute for theophylline in bovine serum albumin and caffeine in imidazoles. This specific molecule also interacts with some other molecules such as photodecomposition of peroxides or acid solutions.</p>

<p>Please enquire for more information about 2’-Nor thiamine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(thiophen-2-yl)acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid is an antimicrobial agent that inhibits bacterial growth by binding to the penicillin binding protein (PBP), which prevents the synthesis of peptidoglycan. This drug has shown effectiveness against gram positive bacteria, including aerobacter aerogenes, as well as infectious diseases in wastewater treatment plants. It has also been demonstrated to be effective in experimental models of infection due to high resistance and cell signaling pathways. The reaction solution was analyzed by plasma mass spectrometry.</p>

<p>6-Methoxy-2-methylquinolin-4(1H)-one is a heterocyclic molecule that has the ability to undergo oxidation reactions. It is an intermediate in the synthesis of other molecules, such as 4-hydroxyquinoline and 4-hydroxybenzaldehyde. The acidity of 6-methoxy-2-methylquinolin-4(1H)-one can be increased by adding alkali, which will cause it to react with hydroxyl and form a phenylhydrazine. When heated with hydrazine, 6-methoxy-2-methylquinolin-4(1H)-one undergoes tautomerism and forms 2-(phenylhydrazinyl) quinoline. The chemical structure of 6-methoxy-2 methylquinolin 4(1H)-one can be detected by analyzing its spectrum (i.e., absorption or emission spectra). This chemical shows bands</p>

<p>Isobergapten is a naturally occurring furanocoumarin, which is primarily derived from plants in the Apiaceae family, such as celery and parsley. The compound is structurally characterized by its fused furan and coumarin rings. It exerts its effects through its ability to interact with cellular enzymes and DNA, often influencing photodynamic processes. This interaction can result in modifications to DNA replication and transcription, making it a compound of interest in photochemotherapy and photobiology.</p>

<p>1H-Cyclopenta[l]phenanthrene is a five-membered cyclic hydrocarbon that binds to phosphine and is used in the synthesis of ferrocenes. It is also unsymmetrical and anion-forming. 1H-Cyclopenta[l]phenanthrene can be protonated at carbon, which makes it a good ligand. 1H-Cyclopenta[l]phenanthrene has been shown to react with carbonyls, imines, and ethylene to form organometallic complexes.</p>

<p>Indole-7-methanol is a flavin cofactor that catalyses the formylation of indole-7-carboxylic acid. Indole-7-methanol can be synthesized by the conversion of indole-7-carboxaldehyde with formaldehyde and ammonium acetate. The macrocyclic, isomeric, and formylated forms of indole-7-methanol have been shown to have utilisation activity in the synthesis of various compounds. These reactions are catalyzed by flavins such as FAD or FMN. Mutant, unsymmetrical derivatives of indole-7-methanol are also known to undergo these types of reactions. The most common derivative is indirubin, which has been shown to inhibit DNA polymerase III and IV in vitro.</p>

<p>Anomelin is a synthetic anticancer compound, which is derived from complex organic synthesis methodologies. This compound is typically produced through careful laboratory processes due to its intricate chemical structure, which is crafted to target specific molecular pathways involved in cancer cell proliferation.</p>

<p>Poly(1,2-dihydro-2,2,4-trimethylquinoline) is a high molecular weight polymeric quinoline. It is an intramolecular hydrogen bond donor. The nitrogen atoms in the polymers are bound to hydrogen and form a ring with two amino groups. Poly(1,2-dihydro-2,2,4-trimethylquinoline) has been shown to be resistant to many chemical agents such as hydrogen fluoride and glycoside derivatives. It also has a carcinogenic potential and can induce liver lesions. The carcinogenesis studies of poly(1,2-dihydro-2,2,4-trimethylquinoline) have shown that it may cause cancer in animals via diazonium salt and methyl ethyl hydrochloric acid</p>

<p>7-Geranyloxycoumarin is a naturally occurring coumarin derivative, which is primarily sourced from plant species in the Rutaceae family. It is a bioactive compound known for its presence in various essential oils and its contribution to the properties of these plant extracts. The mode of action of 7-Geranyloxycoumarin involves interactions at the cellular level, including enzyme inhibition and modulation of signal transduction pathways, which can lead to diverse pharmacological effects.</p>

<p>Please enquire for more information about 1-Methyl-2-(piperazin-1-ylcarbonyl)-1H-indole hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5-Methoxyquinoline (5MQ) is a chemical compound that belongs to the quinoline derivatives. It has shown anticancer activity in tumor models through a proton-transfer mechanism. 5MQ reacts with an acidic proton, such as the hydronium ion, to produce a reactive intermediate that can react with DNA and other cellular macromolecules. The drug also has been shown to inhibit the growth of bacteria by inhibiting protein synthesis. This inhibition is due to its ability to transfer protons from one molecule to another, which alters the charge distribution on that molecule and prevents it from reacting with other molecules.</p>

<p>Cinnoline is a chemical compound that is structurally similar to phenol, containing a hydroxyl group, two nitrogen atoms and a cyclic structure. Cinnoline has been shown to have anti-inflammatory activity in rats with adjuvant-induced arthritis. The mechanism of the anti-inflammatory effect of cinnoline is not fully understood, but it may be due to its stability and ability to bind to biological molecules or its conformational properties. Cinnoline does not react with nitric acid, making it a good candidate for use in infectious diseases such as tuberculosis. It has also been shown to be stable in human serum and has low pharmacokinetic properties. The fluorescence intensity of cinnoline was found to increase when exposed to an electrochemical potential and can be used as a probe molecule for pharmacokinetics studies.</p>

<p>Please enquire for more information about 2-Oxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Methyl 3-formyl-4,6-dimethoxy-1-methyl-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>8-Hydroxyquinoline copper(II) salt is a metal chelate that can be used as an analytical reagent. It is prepared by the reaction of ethylene diamine with 8-hydroxyquinoline and copper(II) chloride. The product has been found to emit light when irradiated with UV light. This product is also used as a substrate for methyl transferase, which is an enzyme involved in the metabolism of drugs. 8-Hydroxyquinoline copper(II) salt has been shown to inhibit the activity of P-glycoprotein (Pgp), which is a drug transporter protein found in mammalian cells that functions to pump xenobiotics from the inside of cells out into the bloodstream. When Pgp is inhibited, it causes cellular accumulation of certain drugs, such as cyclosporin A and tacrolimus.</p>

<p>2-Iodo-1H-imidazole is an asymmetric molecule that is synthesized by a Suzuki coupling reaction between malonic acid and tautomers of 2-iodo-1H-imidazole. This molecule inhibits the activity of inhibitor molecules, such as nitrogen atoms, which are used in pesticide production. It also has pesticidal activity and can be used to treat cancer or autoimmune diseases. 2-Iodo-1H-imidazole is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid.</p>

<p>Graveolone is a bioactive compound that functions as a plant defense enhancer, which is derived from certain plant species known for their antimicrobial properties. Its mode of action involves the activation of multiple signaling pathways that bolster the plant's innate immune response. By enhancing the synthesis of defensive proteins and secondary metabolites, Graveolone effectively fortifies plants against pathogenic challenges and abiotic stresses.</p>