Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1566 produits trouvés pour "Signalisation du cytosquelette"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
LXH254
CAS :LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.Formule :C25H25F3N4O4Degré de pureté :98.3% - 99.92%Couleur et forme :SolidMasse moléculaire :502.49Ref: TM-T11898
1mg50,00€5mg115,00€10mg175,00€25mg344,00€50mg537,00€100mg653,00€200mg898,00€500mg1.369,00€1mL*10mM (DMSO)128,00€NVS-PAK1-1
CAS :NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).Formule :C23H25ClF3N5ODegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :479.93Bisindolylmaleimide VIII acetate
CAS :Bisindolylmaleimide VIII acetate is a selective PKC inhibitor with an IC50 of 158 nM in rat brain and varying IC50s for different PKC isoforms.Formule :C26H26N4O4Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :458.512,3-Butanedione 2-Monoxime
CAS :2,3-Butanedione 2-Monoxime (Diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction.Formule :C4H7NO2Degré de pureté :98.62%Couleur et forme :Physical Description Cream-Colored Powder (Ntp 1992)Masse moléculaire :101.1N-Desmethyl imatinib
CAS :N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Formule :C28H29N7ODegré de pureté :98.60%Couleur et forme :Off-White To Pale-Yellow SolidMasse moléculaire :479.58Ref: TM-T11641
1mg87,00€5mg166,00€10mg303,00€25mg512,00€50mg737,00€100mg1.018,00€1mL*10mM (DMSO)170,00€KY1220
CAS :KY1220 destabilizes both β-catenin and Ras by targeting the Wnt/β-catenin pathway. It has an IC50 of 2.1 μM in HEK293 reporter cells.Formule :C14H10N4O3SDegré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :314.32Ref: TM-T15677
2mg34,00€5mg66,00€10mg101,00€25mg200,00€50mg319,00€100mg515,00€200mg702,00€1mL*10mM (DMSO)70,00€Adropin (34-76) (human, mouse, rat)
CAS :Adropin (34-76) (human, mouse, rat) is a peptide that attenuates liver fibrosis and insulin resistance. Cost-effective and quality-assured.Formule :C190H293N55O68S2Degré de pureté :94.23% - 99.95%Couleur et forme :SolidMasse moléculaire :4499.82GNE 2861
CAS :GNE 2861 inhibits PAK4, PAK5, and PAK6 (IC50s: 7.5, 36, 126 nM, respectively). GNE 2861 is a PAK inhibitor that shows group II selectivity.Formule :C22H26N6O2Degré de pureté :97.03%Couleur et forme :SolidMasse moléculaire :406.48Ref: TM-T16429
1mg40,00€2mg52,00€5mg82,00€10mg124,00€25mg245,00€50mg409,00€100mg605,00€1mL*10mM (DMSO)87,00€BML-286
CAS :BML-286 is a WNT pathway modulator with potential anticancer activity and induces β-catenin- and TCF- dependent transcriptional activity.Formule :C22H18N2O4Degré de pureté :98.44%Couleur et forme :SolidMasse moléculaire :374.39Recilisib
CAS :Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.Formule :C16H13ClO4SDegré de pureté :98.85% - 98.96%Couleur et forme :SolidMasse moléculaire :336.79Ref: TM-T13862
1mg43,00€2mg56,00€5mg93,00€10mg113,00€25mg177,00€50mg295,00€100mg477,00€200mg677,00€1mL*10mM (DMSO)100,00€BOS-172722
CAS :BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).Formule :C24H30N8ODegré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :446.55Mitoxantrone dihydrochloride
CAS :Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II topoisomerase inhibitor.Formule :C22H30Cl2N4O6Degré de pureté :97.05% - >99.99%Couleur et forme :Blue-Black Solid From Water Ethanol SolidMasse moléculaire :517.4Delcasertib
CAS :Delcasertib (KAI-9803) is a potent and selective inhibitor of δ-protein kinase C (δPKC).Formule :C120H199N45O34S2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :2880.28Ref: TM-T11740
1mg192,00€5mg485,00€10mg700,00€25mg1.063,00€50mg1.459,00€100mg1.963,00€1mL*10mM (DMSO)1.603,00€Xentuzumab
CAS :Xentuzumab (BI836845) is a recombinant monoclonal antibody to humanised IGF ligand that inhibits AKT activation and can be used to study solid tumours.Degré de pureté :95.21% - >95.0% (SDS-PAGE); >95.0% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :143.7 kDaATN-161 trifluoroacetate salt
CAS :ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.Formule :C25H36F3N9O10SDegré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :711.67Talquetamab
CAS :Talquetamab (JNJ-64407564) is a T-cell retargeting GPRC5D bispecific antibody with antitumor activity for the treatment of multiple myeloma.Couleur et forme :LiquidMasse moléculaire :144.59 kDaTubulin inhibitor 6
CAS :Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.Formule :C20H14ClNO2SDegré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :367.85CK-666
CAS :CK-666 inhibits Arp2/3 complex, blocking Arp2/3 activation and actin filament formation.Formule :C18H17FN2ODegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :296.34Ref: TM-T10826
1mg38,00€5mg82,00€10mg133,00€25mg266,00€50mg515,00€100mg715,00€200mg895,00€1mL*10mM (DMSO)90,00€Verubulin hydrochloride
CAS :Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxicFormule :C17H18ClN3ODegré de pureté :98.29% - 99.77%Couleur et forme :SolidMasse moléculaire :315.8Ref: TM-T13298
5mg52,00€10mg73,00€25mg138,00€50mg200,00€100mg284,00€200mg411,00€1mL*10mM (DMSO)52,00€Col003
CAS :Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM).Formule :C14H11NO4Degré de pureté :99.03% - 99.96%Couleur et forme :SolidMasse moléculaire :257.24Ref: TM-T10860
2mg44,00€5mg66,00€10mg102,00€25mg205,00€50mg333,00€100mg513,00€200mg737,00€500mg1.108,00€1mL*10mM (DMSO)66,00€Vantictumab
CAS :Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.Degré de pureté :99% (SDS-PAGE); 97.7% (SEC-HPLC) - 99% (SDS-PAGE); 97.7% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :142.69 kDaOxfendazole
CAS :Oxfendazole (RS-8858), a broad spectrum benzimidazole anthelmintic, protects livestock against roundworm, strongyles and pinworms.Formule :C15H13N3O3SDegré de pureté :98.99% - 99.17%Couleur et forme :White To Yellowish PowderMasse moléculaire :315.35Lyn-IN-1
CAS :Lyn-IN-1 (Bafetinib analog) is a selective and potent dual inhibitor of Bcr-Abl and LynFormule :C30H31F3N8ODegré de pureté :97% - 98.02%Couleur et forme :SolidMasse moléculaire :576.62Ref: TM-T11916
1mg38,00€2mg50,00€5mg79,00€10mg117,00€25mg236,00€50mg371,00€100mg530,00€200mg770,00€1mL*10mM (DMSO)92,00€Nilotinib
CAS :Nilotinib (AMN107) is a Bcr-Abl tyrosine kinase inhibitor. Nilotinib has antitumor activity and may be used in CML. Cost-effective and quality-assured.Formule :C28H22F3N7ODegré de pureté :99.89% - >99.99%Couleur et forme :Off-White SolidMasse moléculaire :529.52AKE-72
CAS :AKE-72 is a Pan-BCR-ABL inhibitor with anti-leukemic activity.AKE-72 inhibits the proliferation of Ba/F3 cells expressing natural BCR-ABL or its T315I mutant.Formule :C30H29F3N6ODegré de pureté :98.3%Couleur et forme :SoildMasse moléculaire :546.59Ref: TM-T80676
1mg88,00€2mg129,00€5mg212,00€10mg310,00€25mg479,00€50mg642,00€100mg880,00€200mg1.161,00€Bosutinib
CAS :Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.Formule :C26H29Cl2N5O3Degré de pureté :98.98% - 99.9%Couleur et forme :Yellowish-Orange Or Pink To Brownish Solid Solid PowderMasse moléculaire :530.45Arimoclomol maleate
CAS :Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.Formule :C18H24ClN3O7Degré de pureté :99.44% - 99.98%Couleur et forme :SolidMasse moléculaire :429.85Tilavonemab
CAS :Tilavonemab (ABBV-8E12), a humanized anti-tau antibody, halts tau uptake in neurons and may help with Alzheimer's research.Degré de pureté :95.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 95.2% (SDS-PAGE); 96.6% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.73kDaZagotenemab
CAS :Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.Degré de pureté :> 95% - >95.0% (SDS-PAGE)Couleur et forme :LiquidMasse moléculaire :145.3 kDaBepranemab
CAS :Bepranemab (UCB 0107) - humanized IgG4 monoclonal antibody targeting tau (235-250) for Alzheimer's research.Degré de pureté :99% (SDS-PAGE); 96.8% (SEC-HPLC) - 99% (SDS-PAGE); 96.8% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.92 kDaTINK-IN-1
CAS :TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.Formule :C24H24N4O3Degré de pureté :99.4%Couleur et forme :SoildMasse moléculaire :416.47Ref: TM-T77660
1mg39,00€2mg50,00€5mg82,00€10mg120,00€25mg236,00€50mg353,00€100mg517,00€500mg1.099,00€(+)-Blebbistatin
CAS :(+)-Blebbistatin is the inactive enantiomer of (–)-Blebbistatin. (–)-Blebbistatin is a selective myosin II ATPase inhibitor.
Formule :C18H16N2O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :292.33AS1949490
CAS :AS1949490, a selective SHIP-2 inhibitor with IC50 of 620 nM, boosts glucose metabolism by upregulating GLUT1 in L6 myotubes.Formule :C20H18ClNO2SDegré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :371.88Ref: TM-T14327
1mg38,00€2mg50,00€5mg84,00€10mg119,00€25mg236,00€50mg380,00€100mg555,00€1mL*10mM (DMSO)93,00€Glofitamab
CAS :Glofitamab (RO7082859), a bivalent antibody, targets CD20 on B-cells to aid T cell attack in relapsed/refractory lymphomas.
Degré de pureté :SDS-PAGE:98.2%;SEC-HPLC:98.0%Couleur et forme :LiquidMasse moléculaire :170.37 kDaDasatinib monohydrate
CAS :Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.Formule :C22H28ClN7O3SDegré de pureté :99.68% - >99.99%Couleur et forme :SolidMasse moléculaire :506.03Orbofiban TFA
CAS :Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronaryFormule :C19H24F3N5O6Degré de pureté :97.21% - 98.72%Couleur et forme :SolidMasse moléculaire :475.42Pamidronate Disodium
CAS :Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.Formule :C3H9NNa2O7P2Degré de pureté :99.86% - 99.93%Couleur et forme :White CrystalsMasse moléculaire :279.03Spiperone
CAS :Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds.Formule :C23H26FN3O2Degré de pureté :99.34% - 99.91%Couleur et forme :SolidMasse moléculaire :395.47Abciximab
CAS :Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Degré de pureté :SDS-PAGE:95.2%;SEC-HPLC:95.9%Couleur et forme :LiquidMasse moléculaire :95.18 kDaNMS-P715
CAS :NMS-P715 is a highly selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).Formule :C35H39F3N8O3Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :676.73CWP232228
CAS :CWP232228 is a selective Wnt/β-catenin pathway inhibitor targeting β-catenin/TCF binding, halting breast/liver CSC growth and metastasis safely.Formule :C33H34N7Na2O7PDegré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :717.63JW74
CAS :JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).Formule :C24H20N6O2SDegré de pureté :95.00%Couleur et forme :SolidMasse moléculaire :456.52Abituzumab
CAS :Abituzumab (DI17E6) is a humanized monoclonal antibody targeting integrin alphaV, exhibiting anti-cancer activity and can be used in prostate cancer research.Degré de pureté :>95%Couleur et forme :LiquidMasse moléculaire :144.58 kDaForalumab
CAS :Foralumab (NI-0401) is a human anti-CD3 monoclonal antibody for the study of COVID-19 infection.Degré de pureté :96.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :146.59 kDaTNIK-IN-5
CAS :TNIK-IN-5: strong TNIK inhibitor (IC50=0.05μM), halts Wnt signaling, effective against colorectal cancer in vitro.Formule :C22H17N3O3Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :371.39Tadocizumab
CAS :Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.Degré de pureté :97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :47.59 kDaBersanlimab
CAS :Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.Degré de pureté :> 95% - > 95%Couleur et forme :LiquidMasse moléculaire :144.22 kDaGRP78-IN-3
CAS :GRP78-IN-3: Potent Hsp70 blocker, selective Grp78 (HSPA5) inhib., IC50 0.59 μM, 7x more vs HspA9, 20x vs HspA2.Formule :C17H18N4O2SDegré de pureté :99.49%Couleur et forme :SoildMasse moléculaire :342.42Ethoxyquin
CAS :Ethoxyquin (Santoflex) is an antioxidant used in animal feeds.Formule :C14H19NODegré de pureté :97.15% - 98.73%Couleur et forme :Yellow Liquid Mercaptan-Like Odor (Ntp 1992)Masse moléculaire :217.31Entasobulin
CAS :Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.Formule :C26H18ClN3O2Degré de pureté :98.40%Couleur et forme :SolidMasse moléculaire :439.89Elarofiban TFA
CAS :Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease.Formule :C26H34F6N4O8Degré de pureté :99.08%Couleur et forme :SoildMasse moléculaire :644.56AC 7739
CAS :AC 7739 is a microtubule protein binding agent with anticancer and antitumor activity that inhibits advanced solid tumors and in situ transplanted tumors.Formule :C18H22ClNO4Degré de pureté :99.38% - 99.55%Couleur et forme :SoildMasse moléculaire :351.83IPI-493
CAS :IPI-493 is a bioactive chemical.Formule :C28H39N3O8Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :545.62Akt3 degrader 1
CAS :Akt3 degrader 1 counters Osimertinib resistance in NSCLC, inhibits cell growth, and reduces mouse tumors.Formule :C53H72N8O4Degré de pureté :98.12% - 99.02%Couleur et forme :SolidMasse moléculaire :885.19ADH-1 trifluoroacetate
CAS :ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities.Formule :C24H35F3N8O8S2Degré de pureté :90.08% - 99.98%Couleur et forme :SolidMasse moléculaire :684.71Ref: TM-T1608
2mg42,00€5mg62,00€10mg89,00€25mg167,00€50mg227,00€100mg339,00€200mg482,00€1mL*10mM (DMSO)89,00€CC-99677
CAS :CC-99677 (Gamcemetinib) is a MK2 inhibitor targeting autoimmune diseases; potent in rat assays with IC50=156.3 nM & EC50=89 nM.Formule :C22H20ClN5O3SDegré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :469.94PKC β pseudosubstrate acetate
PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.Degré de pureté :95.42%Couleur et forme :SoildImatinib Mesylate
CAS :Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,
Formule :C29H31N7O·CH4SO3Degré de pureté :98% - >99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :589.71Arg-Gly-Asp-Ser acetate
Arg-Gly-Asp-Ser acetate targets integrin, binding pro-caspase-8, -9, -3, but not -1; inhibits receptor function.Formule :C17H31N7O10Degré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :493.47Donanemab
CAS :Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :145.36 kDaAbrilumab
CAS :Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.Degré de pureté :98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :143.80 kDaIMAB027
CAS :Naratuximab (Anti-TSPAN26/CD37 Reference Antibody) is a humanized monoclonal antibody against CD37 that can be used to synthesize ADC compounds.Degré de pureté :97.7% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.5% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :144.42 kDaRWJ 50271
CAS :RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.Formule :C18H17F3N4O2SDegré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :410.41Ref: TM-T12783
1mg120,00€5mg295,00€10mg447,00€25mg707,00€50mg964,00€100mg1.243,00€200mg1.693,00€1mL*10mM (DMSO)326,00€Danicamtiv
CAS :Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin.Formule :C16H20F3N5O4SDegré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :435.42Ref: TM-T15050
1mg129,00€5mg260,00€10mg430,00€25mg710,00€50mg973,00€100mg1.333,00€1mL*10mM (DMSO)286,00€Teplizumab
CAS :Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.Degré de pureté :SDS-PAGE:95.8%;SEC-HPLC:99.7%Couleur et forme :LiquidMasse moléculaire :145.79 kDaFluocinolone (Acetonide)
CAS :Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.Formule :C24H30F2O6Degré de pureté :99.29% - 99.82%Couleur et forme :Crystals From Acetone & Hexane SolidMasse moléculaire :452.49Dasatinib
CAS :Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.Formule :C22H26ClN7O2SDegré de pureté :99.59% - 99.86%Couleur et forme :Pale-Yellow SolidMasse moléculaire :488.01CMPD101
CAS :CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).Formule :C24H21F3N6ODegré de pureté :99.01% - 99.04%Couleur et forme :SolidMasse moléculaire :466.46Fluorofenidone
CAS :Fluorofenidone (AKF-PD) slows kidney fibrosis by inhibiting NADPH oxidase/ECM via PI3K/Akt, akin to AMR69 but less toxic with a longer half-life.Formule :C12H10FNODegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :203.21Ref: TM-T15300
2mg34,00€5mg49,00€10mg80,00€25mg147,00€50mg259,00€100mg371,00€200mg523,00€1mL*10mM (DMSO)54,00€ATN-161 acetate
CAS :ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.Formule :C25H39N9O10SDegré de pureté :98.27%Couleur et forme :SoildMasse moléculaire :657.7Ref: TM-T10398L
1mg190,00€5mg471,00€10mg663,00€25mg1.036,00€50mg1.429,00€100mg1.830,00€200mg2.498,00€Cibisatamab
CAS :Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.Degré de pureté :SDS-PAGE:99.1%;SEC-HPLC:96.5%Couleur et forme :LiquidMasse moléculaire :191.1 kDaN-Desmethyltamoxifen hydrochloride
CAS :N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.Formule :C25H28ClNODegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :393.95Otelixizumab
CAS :Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.Degré de pureté :>95%Couleur et forme :LiquidMeclofenamic acid sodium
CAS :Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities.Formule :C14H10Cl2NNaO2Degré de pureté :98% - 98.96%Couleur et forme :SolidMasse moléculaire :318.14Larazotide acetate
CAS :Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state.Formule :C34H59N9O12Degré de pureté :95.53% - 99.425%Couleur et forme :SolidMasse moléculaire :785.89Paprotrain
CAS :Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.Formule :C16H11N3Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :245.28Ref: TM-T12359
5mg46,00€10mg58,00€25mg92,00€50mg160,00€100mg236,00€200mg353,00€500mg580,00€1mL*10mM (DMSO)49,00€Darifenacin hydrobromide
CAS :Darifenacin hydrobromide (UK-88525) is a selective muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.Formule :C28H31BrN2O2Degré de pureté :99.75% - >99.99%Couleur et forme :SolidMasse moléculaire :505.45SGC-AAK1-1
CAS :SGC-AAK1-1 is a potent and selective inhibitor of AAK1 (AP2 associated kinase 1) (IC50 of 270 nM and a Ki of 9 nM),and is a chemical probe.
Formule :C21H25N5O3SDegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :427.52Mps1-IN-3
CAS :Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Formule :C26H31N7O4SDegré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :537.63Ref: TM-T16130
2mg34,00€5mg54,00€10mg87,00€25mg149,00€50mg255,00€100mg384,00€200mg538,00€1mL*10mM (DMSO)64,00€BNC105
CAS :BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.Formule :C20H20O7Degré de pureté :96.57%Couleur et forme :SolidMasse moléculaire :372.37Ref: TM-T14694
1mg79,00€5mg152,00€10mg215,00€25mg351,00€50mg494,00€100mg665,00€200mg893,00€1mL*10mM (DMSO)167,00€A-3 hydrochloride
CAS :A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.Formule :C12H14Cl2N2O2SDegré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :321.22Ref: TM-T14069
1mg34,00€5mg63,00€10mg90,00€25mg161,00€50mg260,00€100mg416,00€500mg888,00€1mL*10mM (DMSO)95,00€7-Aminocephalosporanic acid
CAS :7-Aminocephalosporanic acid (7-ACA) is used for synthesis of cephalosporin antibiotics and intermediates.Formule :C10H12N2O5SDegré de pureté :91.05%Couleur et forme :White Solid PowderMasse moléculaire :272.28ML-9
CAS :ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively.Formule :C15H18Cl2N2O2SDegré de pureté :99.69%Couleur et forme :Crystalline SolidMasse moléculaire :361.29Nefopam hydrochloride
CAS :Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.Formule :C17H20ClNODegré de pureté :99.32% - 99.85%Couleur et forme :SolidMasse moléculaire :289.8Coronaridine
CAS :Coronaridine is a useful organic compound for research related to life sciences. The catalog number is T124824 and the CAS number is 467-77-6.
Formule :C21H26N2O2Couleur et forme :SolidMasse moléculaire :338.451Tubulin polymerization-IN-46
Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breastFormule :C22H25NO6Couleur et forme :SolidMasse moléculaire :399.44Mps1-IN-6
Mps1-IN-6 is a potent Mps1 inhibitor that demonstrates antiproliferative and antitumor activities, exhibiting an IC50 of 2.596 nM [1].Formule :C35H39N9O3Couleur et forme :SolidMasse moléculaire :633.74Zolbetuximab
CAS :Zolbetuximab (IMAB362) is a monoclonal antibody targeting Claudin-18.2 for certain gastrointestinal and pancreatic cancers.
Degré de pureté :95.3% (SDS-PAGE); 95.1% (SEC-HPLC) - 97%+Couleur et forme :LiquidMasse moléculaire :147.09 kDaMK2-IN-5
CAS :MK2-IN-5, a pseudosubstrate of Mk2 with an inhibition constant (K_i) of 8 μM, selectively targets the protein interaction domain of the MAPK pathway andFormule :C61H113N21O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1396.68trans-Dehydrocurvularin
CAS :trans-Dehydrocurvularin is a useful organic compound for research related to life sciences. The catalog number is T125357 and the CAS number is 21178-57-4.Formule :C16H18O5Couleur et forme :SolidMasse moléculaire :290.315Bisindolylmaleimide III
CAS :Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6Formule :C23H20N4O2Degré de pureté :97.2%Couleur et forme :SolidMasse moléculaire :384.43JG-258
CAS :JG-258 is an inactive negative control for Hsp70 inhibitors [1] .Formule :C20H22ClN3OS3Couleur et forme :SolidMasse moléculaire :452.06Abl Cytosolic Substrate
CAS :Abl Cytosolic Substrate is a substrate for Abelson tyrosine kinase (Abl ).Formule :C64H101N15O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1336.58Tubulin inhibitor 36
Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,Formule :C16H13ClN6SCouleur et forme :SolidMasse moléculaire :356.83Ceratamine A
CAS :Ceratamine A, from Pseudoceratina sponge, is a cytotoxic, microtubule-stabilizing antimitotic alkaloid.
Formule :C17H16Br2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.146BrCaQ-C10-TPP
6BrCaQ-C10-TPP inhibits TRAP1, halts cancer cell growth (IC50=0.008-0.30µM), disrupts mitochondrial membrane.Formule :C45H47Br2N2O3PCouleur et forme :SolidMasse moléculaire :854.65hCA/Wnt/β-catenin-IN-1
hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8Couleur et forme :Odour SolidSNIPER(ABL)-015
SNIPER(ABL)-015, a compound that conjugates GNF5 (ABL inhibitor) to MV-1 (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of 5Formule :C58H70F3N9O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1094.23Myosin V-IN-1
CAS :Myosin V-IN-1: potent, selective Myosin V inhibitor, Ki of 6 μM; hinders actin-activated ATPase by blocking ADP release.
Formule :C29H26N6O3SDegré de pureté :98.64% - 98.64%Couleur et forme :SolidMasse moléculaire :538.62Gantofiban
CAS :Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.Formule :C21H29N5O6Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :447.48
