Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1534 produits trouvés pour "Signalisation du cytosquelette"
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SGC-AAK1-1
CAS :SGC-AAK1-1 is a potent and selective inhibitor of AAK1 (AP2 associated kinase 1) (IC50 of 270 nM and a Ki of 9 nM),and is a chemical probe.
Formule :C21H25N5O3SDegré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :427.52CWP232228
CAS :CWP232228 is a selective Wnt/β-catenin pathway inhibitor targeting β-catenin/TCF binding, halting breast/liver CSC growth and metastasis safely.Formule :C33H34N7Na2O7PDegré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :717.63Adropin (34-76) (human, mouse, rat)
CAS :Adropin (34-76) (human, mouse, rat) is a peptide that attenuates liver fibrosis and insulin resistance. Cost-effective and quality-assured.Formule :C190H293N55O68S2Degré de pureté :94.23% - 99.95%Couleur et forme :SolidMasse moléculaire :4499.82Darifenacin hydrobromide
CAS :Darifenacin hydrobromide (UK-88525) is a selective muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.Formule :C28H31BrN2O2Degré de pureté :99.75% - >99.99%Couleur et forme :SolidMasse moléculaire :505.457-Aminocephalosporanic acid
CAS :7-Aminocephalosporanic acid (7-ACA) is used for synthesis of cephalosporin antibiotics and intermediates.Formule :C10H12N2O5SDegré de pureté :91.05%Couleur et forme :White Solid PowderMasse moléculaire :272.28Nefopam hydrochloride
CAS :Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.Formule :C17H20ClNODegré de pureté :99.32% - 99.85%Couleur et forme :SolidMasse moléculaire :289.8Teplizumab
CAS :Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.Degré de pureté :SDS-PAGE:95.8%;SEC-HPLC:99.7%Couleur et forme :LiquidMasse moléculaire :145.79 kDaTalquetamab
CAS :Talquetamab (JNJ-64407564) is a T-cell retargeting GPRC5D bispecific antibody with antitumor activity for the treatment of multiple myeloma.Couleur et forme :LiquidMasse moléculaire :144.59 kDaOrbofiban TFA
CAS :Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronaryFormule :C19H24F3N5O6Degré de pureté :97.21% - 98.72%Couleur et forme :SolidMasse moléculaire :475.42Pamidronate Disodium
CAS :Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.Formule :C3H9NNa2O7P2Degré de pureté :99.86% - 99.93%Couleur et forme :White CrystalsMasse moléculaire :279.03CK-666
CAS :CK-666 inhibits Arp2/3 complex, blocking Arp2/3 activation and actin filament formation.Formule :C18H17FN2ODegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :296.34Ref: TM-T10826
1mg38,00€5mg82,00€10mg133,00€25mg266,00€50mg515,00€100mg715,00€200mg895,00€1mL*10mM (DMSO)90,00€Bisindolylmaleimide VIII acetate
CAS :Bisindolylmaleimide VIII acetate is a selective PKC inhibitor with an IC50 of 158 nM in rat brain and varying IC50s for different PKC isoforms.Formule :C26H26N4O4Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :458.51NMS-P715
CAS :NMS-P715 is a highly selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).Formule :C35H39F3N8O3Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :676.73ML-9
CAS :ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively.Formule :C15H18Cl2N2O2SDegré de pureté :99.69%Couleur et forme :Crystalline SolidMasse moléculaire :361.29ATN-161 acetate
CAS :ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.Formule :C25H39N9O10SDegré de pureté :98.27%Couleur et forme :SoildMasse moléculaire :657.7Ref: TM-T10398L
1mg190,00€5mg471,00€10mg663,00€25mg1.036,00€50mg1.429,00€100mg1.830,00€200mg2.498,00€TINK-IN-1
CAS :TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.Formule :C24H24N4O3Degré de pureté :99.4%Couleur et forme :SoildMasse moléculaire :416.47Ref: TM-T77660
1mg39,00€2mg50,00€5mg82,00€10mg120,00€25mg236,00€50mg353,00€100mg517,00€500mg1.099,00€ATN-161 trifluoroacetate salt
CAS :ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.Formule :C25H36F3N9O10SDegré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :711.67Glofitamab
CAS :Glofitamab (RO7082859), a bivalent antibody, targets CD20 on B-cells to aid T cell attack in relapsed/refractory lymphomas.
Degré de pureté :SDS-PAGE:98.2%;SEC-HPLC:98.0%Couleur et forme :LiquidMasse moléculaire :170.37 kDaN-Desmethyltamoxifen hydrochloride
CAS :N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.Formule :C25H28ClNODegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :393.95Meclofenamic acid sodium
CAS :Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities.Formule :C14H10Cl2NNaO2Degré de pureté :98% - 98.96%Couleur et forme :SolidMasse moléculaire :318.14Tubulin inhibitor 6
CAS :Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.Formule :C20H14ClNO2SDegré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :367.85Paprotrain
CAS :Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.Formule :C16H11N3Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :245.28Ref: TM-T12359
5mg46,00€10mg58,00€25mg92,00€50mg160,00€100mg236,00€200mg353,00€500mg580,00€1mL*10mM (DMSO)49,00€CMPD101
CAS :CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).Formule :C24H21F3N6ODegré de pureté :99.01% - 99.04%Couleur et forme :SolidMasse moléculaire :466.46Spiperone
CAS :Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds.Formule :C23H26FN3O2Degré de pureté :99.34% - 99.91%Couleur et forme :SolidMasse moléculaire :395.47Zagotenemab
CAS :Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.Degré de pureté :> 95% - >95.0% (SDS-PAGE)Couleur et forme :LiquidMasse moléculaire :145.3 kDaGNE 2861
CAS :GNE 2861 inhibits PAK4, PAK5, and PAK6 (IC50s: 7.5, 36, 126 nM, respectively). GNE 2861 is a PAK inhibitor that shows group II selectivity.Formule :C22H26N6O2Degré de pureté :97.03%Couleur et forme :SolidMasse moléculaire :406.48Ref: TM-T16429
1mg40,00€2mg52,00€5mg82,00€10mg124,00€25mg245,00€50mg409,00€100mg605,00€1mL*10mM (DMSO)87,00€Imatinib Mesylate
CAS :Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,
Formule :C29H31N7O·CH4SO3Degré de pureté :98% - >99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :589.71Danicamtiv
CAS :Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin.Formule :C16H20F3N5O4SDegré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :435.42Ref: TM-T15050
1mg129,00€5mg260,00€10mg430,00€25mg710,00€50mg973,00€100mg1.333,00€1mL*10mM (DMSO)286,00€CC-99677
CAS :CC-99677 (Gamcemetinib) is a MK2 inhibitor targeting autoimmune diseases; potent in rat assays with IC50=156.3 nM & EC50=89 nM.Formule :C22H20ClN5O3SDegré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :469.94Verubulin hydrochloride
CAS :Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxicFormule :C17H18ClN3ODegré de pureté :98.29% - 99.77%Couleur et forme :SolidMasse moléculaire :315.8Ref: TM-T13298
5mg52,00€10mg73,00€25mg138,00€50mg200,00€100mg284,00€200mg411,00€1mL*10mM (DMSO)52,00€RWJ 50271
CAS :RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.Formule :C18H17F3N4O2SDegré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :410.41Ref: TM-T12783
1mg120,00€5mg295,00€10mg447,00€25mg707,00€50mg964,00€100mg1.243,00€200mg1.693,00€1mL*10mM (DMSO)326,00€IMAB027
CAS :Naratuximab (Anti-TSPAN26/CD37 Reference Antibody) is a humanized monoclonal antibody against CD37 that can be used to synthesize ADC compounds.
Degré de pureté :97.7% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.5% (SEC-HPLC)Couleur et forme :LiquidDelcasertib
CAS :Delcasertib (KAI-9803) is a potent and selective inhibitor of δ-protein kinase C (δPKC).Formule :C120H199N45O34S2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :2880.28Ref: TM-T11740
1mg192,00€5mg485,00€10mg700,00€25mg1.063,00€50mg1.459,00€100mg1.963,00€1mL*10mM (DMSO)1.603,00€Dasatinib
CAS :Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.Formule :C22H26ClN7O2SDegré de pureté :99.59% - 99.86%Couleur et forme :Pale-Yellow SolidMasse moléculaire :488.01Fluocinolone (Acetonide)
CAS :Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.Formule :C24H30F2O6Degré de pureté :99.29% - 99.82%Couleur et forme :Crystals From Acetone & Hexane SolidMasse moléculaire :452.49(+)-Blebbistatin
CAS :(+)-Blebbistatin is the inactive enantiomer of (–)-Blebbistatin. (–)-Blebbistatin is a selective myosin II ATPase inhibitor.
Formule :C18H16N2O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :292.33BNC105
CAS :BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.Formule :C20H20O7Degré de pureté :96.57%Couleur et forme :SolidMasse moléculaire :372.37Ref: TM-T14694
1mg79,00€5mg152,00€10mg215,00€25mg351,00€50mg494,00€100mg665,00€200mg893,00€1mL*10mM (DMSO)167,00€Fluorofenidone
CAS :Fluorofenidone (AKF-PD) slows kidney fibrosis by inhibiting NADPH oxidase/ECM via PI3K/Akt, akin to AMR69 but less toxic with a longer half-life.
Formule :C12H10FNODegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :203.21AS1949490
CAS :AS1949490, a selective SHIP-2 inhibitor with IC50 of 620 nM, boosts glucose metabolism by upregulating GLUT1 in L6 myotubes.Formule :C20H18ClNO2SDegré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :371.88Ref: TM-T14327
1mg38,00€2mg50,00€5mg84,00€10mg119,00€25mg236,00€50mg380,00€100mg555,00€1mL*10mM (DMSO)93,00€Cibisatamab
CAS :Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.Degré de pureté :SDS-PAGE:99.1%;SEC-HPLC:96.5%Couleur et forme :LiquidMasse moléculaire :191.1 kDaDasatinib monohydrate
CAS :Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.Formule :C22H28ClN7O3SDegré de pureté :99.68% - >99.99%Couleur et forme :SolidMasse moléculaire :506.03Otelixizumab
CAS :Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.Degré de pureté :>95%Couleur et forme :LiquidMps1-IN-3
CAS :Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Formule :C26H31N7O4SDegré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :537.63Ref: TM-T16130
2mg34,00€5mg54,00€10mg87,00€25mg149,00€50mg255,00€100mg384,00€200mg538,00€1mL*10mM (DMSO)64,00€ADH-1 trifluoroacetate
CAS :ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities.Formule :C24H35F3N8O8S2Degré de pureté :90.08% - 99.98%Couleur et forme :SolidMasse moléculaire :684.71Ref: TM-T1608
2mg42,00€5mg62,00€10mg89,00€25mg167,00€50mg227,00€100mg339,00€200mg482,00€1mL*10mM (DMSO)89,00€A-3 hydrochloride
CAS :A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.Formule :C12H14Cl2N2O2SDegré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :321.22Ref: TM-T14069
1mg34,00€5mg63,00€10mg90,00€25mg161,00€50mg260,00€100mg416,00€500mg888,00€1mL*10mM (DMSO)95,00€Larazotide acetate
CAS :Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state.Formule :C34H59N9O12Degré de pureté :95.53% - 99.425%Couleur et forme :SolidMasse moléculaire :785.89Bosutinib
CAS :Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.Formule :C26H29Cl2N5O3Degré de pureté :98.98% - 99.9%Couleur et forme :Yellowish-Orange Or Pink To Brownish Solid Solid PowderMasse moléculaire :530.45Abciximab
CAS :Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.Degré de pureté :SDS-PAGE:95.2%;SEC-HPLC:95.9%Couleur et forme :LiquidMasse moléculaire :95.18 kDaPKC β pseudosubstrate acetate
PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.Degré de pureté :95.42%Couleur et forme :SoildNVS-PAK1-1
CAS :NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).Formule :C23H25ClF3N5ODegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :479.93
