Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1382 produits trouvés pour "Signalisation du cytosquelette"
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Tidutamab
CAS :<p>Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T cell binding domain (CD3).</p>Degré de pureté :97.9% (SDS-PAGE); 97.8% (SEC-HPLC) - 97.9% (SDS-PAGE); 97.8% (SEC-HPLC)Couleur et forme :LiquidTirbanibulin Mesylate
CAS :<p>Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).</p>Formule :C27H33N3O6SDegré de pureté :99%Couleur et forme :SolidMasse moléculaire :527.63Tilavonemab
CAS :<p>Tilavonemab (ABBV-8E12), a humanized anti-tau antibody, halts tau uptake in neurons and may help with Alzheimer's research.</p>Degré de pureté :95.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 95.2% (SDS-PAGE); 96.6% (SEC-HPLC)Couleur et forme :LiquidN-Desmethyltamoxifen hydrochloride
CAS :<p>N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.</p>Formule :C25H28ClNODegré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :393.95Tubulin inhibitor 6
CAS :<p>Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.</p>Formule :C20H14ClNO2SDegré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :367.85Donanemab
CAS :<p>Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.</p>Degré de pureté :95%Couleur et forme :LiquidATN-161 acetate
CAS :<p>ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.</p>Formule :C25H39N9O10SDegré de pureté :98.27%Couleur et forme :SoildMasse moléculaire :657.7Fluocinolone (Acetonide)
CAS :<p>Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.</p>Formule :C24H30F2O6Degré de pureté :99.29% - 99.82%Couleur et forme :Crystals From Acetone & Hexane SolidMasse moléculaire :452.49Talquetamab
CAS :<p>Talquetamab (JNJ-64407564) is a T-cell retargeting GPRC5D bispecific antibody with antitumor activity for the treatment of multiple myeloma.</p>Couleur et forme :LiquidMasse moléculaire :144.59 kDaForalumab
CAS :<p>Foralumab (NI-0401) is a human anti-CD3 monoclonal antibody for the study of COVID-19 infection.</p>Degré de pureté :96.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)Couleur et forme :LiquidOrbofiban TFA
CAS :<p>Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronary</p>Formule :C19H24F3N5O6Degré de pureté :97.21% - 98.72%Couleur et forme :SolidMasse moléculaire :475.42Tadocizumab
CAS :<p>Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.</p>Degré de pureté :97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)Couleur et forme :LiquidPaprotrain
CAS :<p>Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.</p>Formule :C16H11N3Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :245.28Vantictumab
CAS :<p>Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.</p>Degré de pureté :99% (SDS-PAGE); 97.7% (SEC-HPLC) - 99% (SDS-PAGE); 97.7% (SEC-HPLC)Couleur et forme :LiquidDanicamtiv
CAS :<p>Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin.</p>Formule :C16H20F3N5O4SDegré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :435.42CMPD101
CAS :<p>CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).</p>Formule :C24H21F3N6ODegré de pureté :99.01% - 99.04%Couleur et forme :SolidMasse moléculaire :466.46AS1949490
CAS :<p>AS1949490, a selective SHIP-2 inhibitor with IC50 of 620 nM, boosts glucose metabolism by upregulating GLUT1 in L6 myotubes.</p>Formule :C20H18ClNO2SDegré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :371.88Teplizumab
CAS :<p>Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.</p>Degré de pureté :SDS-PAGE:95.8%;SEC-HPLC:99.7%Couleur et forme :LiquidMasse moléculaire :145.79 kDa(+)-Blebbistatin
CAS :<p>(+)-Blebbistatin is the inactive enantiomer of (–)-Blebbistatin. (–)-Blebbistatin is a selective myosin II ATPase inhibitor.</p>Formule :C18H16N2O2Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :292.33Glofitamab
CAS :<p>Glofitamab (RO7082859), a bivalent antibody, targets CD20 on B-cells to aid T cell attack in relapsed/refractory lymphomas.</p>Degré de pureté :SDS-PAGE:98.2%;SEC-HPLC:98.0%Couleur et forme :LiquidMasse moléculaire :170.37 kDaMosunetuzumab
CAS :<p>Mosunetuzumab (BCT-4465A) is an IgG1 antibody targeting CD20 & CD3, used for R/R B-NHL and refractory follicular lymphoma.</p>Degré de pureté :SDS-PAGE:94.4%;SEC-HPLC:96.1%Couleur et forme :LiquidMasse moléculaire :146.27 kDaVeltuzumab
CAS :<p>Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody that shows anti-proliferative, apoptotic and antibody-dependent cytotoxic effects in vitro.</p>Degré de pureté :97.7% (SDS-PAGE); 97.9% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.9% (SEC-HPLC)Couleur et forme :LiquidDasatinib monohydrate
CAS :<p>Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.</p>Formule :C22H28ClN7O3SDegré de pureté :99.68% - >99.99%Couleur et forme :SolidMasse moléculaire :506.03Meclofenamic acid sodium
CAS :<p>Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities.</p>Formule :C14H10Cl2NNaO2Degré de pureté :98% - 98.96%Couleur et forme :SolidMasse moléculaire :318.14PKC β pseudosubstrate acetate
<p>PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.</p>Degré de pureté :95.42%Couleur et forme :SoildBosutinib
CAS :<p>Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.</p>Formule :C26H29Cl2N5O3Degré de pureté :98.98% - 99.9%Couleur et forme :Yellowish-Orange Or Pink To Brownish Solid Solid PowderMasse moléculaire :530.45Efalizumab
CAS :<p>Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.</p>Degré de pureté :SDS-PAGE:95% SEC-HPLC:98.77%Couleur et forme :LiquidMasse moléculaire :146.14 kDaLarazotide acetate
CAS :<p>Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state.</p>Formule :C34H59N9O12Degré de pureté :95.53% - 99.425%Couleur et forme :SolidMasse moléculaire :785.89Zagotenemab
CAS :<p>Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.</p>Degré de pureté :95% - > 95%Couleur et forme :LiquidMasse moléculaire :145.3 kDaA-3 hydrochloride
CAS :<p>A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.</p>Formule :C12H14Cl2N2O2SDegré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :321.22RWJ 50271
CAS :<p>RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.</p>Formule :C18H17F3N4O2SDegré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :410.41CC-99677
CAS :<p>CC-99677 (Gamcemetinib) is a MK2 inhibitor targeting autoimmune diseases; potent in rat assays with IC50=156.3 nM & EC50=89 nM.</p>Formule :C22H20ClN5O3SDegré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :469.94ADH-1 trifluoroacetate
CAS :<p>ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities.</p>Formule :C24H35F3N8O8S2Degré de pureté :90.08% - 99.17%Couleur et forme :SolidMasse moléculaire :684.71Imatinib Mesylate
CAS :<p>Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,</p>Formule :C29H31N7O·CH4SO3Degré de pureté :98% - >99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :589.71Dasatinib
CAS :<p>Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.</p>Formule :C22H26ClN7O2SDegré de pureté :99.59% - 99.86%Couleur et forme :Pale-Yellow SolidMasse moléculaire :488.01IMAB027
CAS :<p>Naratuximab (Anti-TSPAN26/CD37 Reference Antibody) is a humanized monoclonal antibody against CD37 that can be used to synthesize ADC compounds.</p>Degré de pureté :97.7% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.5% (SEC-HPLC)Couleur et forme :LiquidDelcasertib
CAS :<p>Delcasertib (KAI-9803) is a potent and selective inhibitor of δ-protein kinase C (δPKC).</p>Formule :C120H199N45O34S2Degré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :2880.28TINK-IN-1
CAS :<p>TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.</p>Formule :C24H24N4O3Degré de pureté :99.4%Couleur et forme :SoildMasse moléculaire :416.47BNC105
CAS :<p>BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.</p>Formule :C20H20O7Degré de pureté :96.57%Couleur et forme :SolidMasse moléculaire :372.37Bepranemab
CAS :<p>Bepranemab (UCB 0107) - humanized IgG4 monoclonal antibody targeting tau (235-250) for Alzheimer's research.</p>Degré de pureté :99% (SDS-PAGE); 96.8% (SEC-HPLC) - 99% (SDS-PAGE); 96.8% (SEC-HPLC)Couleur et forme :LiquidATN-161 trifluoroacetate salt
CAS :<p>ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.</p>Formule :C25H36F3N9O10SDegré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :711.67Fluorofenidone
CAS :<p>Fluorofenidone (AKF-PD) slows kidney fibrosis by inhibiting NADPH oxidase/ECM via PI3K/Akt, akin to AMR69 but less toxic with a longer half-life.</p>Formule :C12H10FNODegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :203.21Adropin (34-76) (human, mouse, rat)
CAS :<p>Adropin (34-76) (human, mouse, rat) is a peptide that attenuates liver fibrosis and insulin resistance. Cost-effective and quality-assured.</p>Formule :C190H293N55O68S2Degré de pureté :94.23% - 99.95%Couleur et forme :SolidMasse moléculaire :4499.82ALK inhibitor 2
CAS :<p>ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.</p>Formule :C23H28ClN7O3SDegré de pureté :99.77% - >99.99%Couleur et forme :SolidMasse moléculaire :518.03Abrilumab
CAS :<p>Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.</p>Degré de pureté :98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Couleur et forme :LiquidCibisatamab
CAS :<p>Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.</p>Degré de pureté :SDS-PAGE:99.1%;SEC-HPLC:96.5%Couleur et forme :LiquidMasse moléculaire :191.1 kDaMps1-IN-3
CAS :<p>Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).</p>Formule :C26H31N7O4SDegré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :537.63Abciximab
CAS :<p>Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.</p>Degré de pureté :SDS-PAGE:95.2%;SEC-HPLC:95.9%Couleur et forme :LiquidMasse moléculaire :95.18 kDaOtelixizumab
CAS :<p>Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.</p>Degré de pureté :>95%Couleur et forme :LiquidPamidronate Disodium
CAS :<p>Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.</p>Formule :C3H9NNa2O7P2Degré de pureté :99.86% - 99.93%Couleur et forme :White CrystalsMasse moléculaire :279.03
