Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1382 produits trouvés pour "Signalisation du cytosquelette"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Pep2m, myristoylated acetate
<p>Pep2m, a myristoylated acetate, inhibits GluA2-NSF interaction, reducing AMPA receptor function and expression in neurons.</p>Formule :C65H122N18O16SDegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :1443.96Teduglutide acetate
<p>Teduglutide acetate, a GLP-2 analogue, maximizes small intestinal mucosal hypertrophy.</p>Formule :C166H256N44O56SDegré de pureté :97.39%Couleur et forme :SoildMasse moléculaire :3812.13Vodobatinib
CAS :<p>Vodobatinib (K-0706) is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 with limited off-target activity.</p>Formule :C27H20ClN3O2Degré de pureté :99.06% - 99.55%Couleur et forme :SolidMasse moléculaire :453.92Decursin
CAS :<p>Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.</p>Formule :C19H20O5Degré de pureté :97.22% - 99.84%Couleur et forme :SolidMasse moléculaire :328.36Taurochenodeoxycholic acid sodium
CAS :<p>Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).</p>Formule :C26H44NNaO6SDegré de pureté :98.23% - 99.45%Couleur et forme :White To Off-White PowderMasse moléculaire :521.68Pimitespib
CAS :<p>Pimitespib (TAS-116) is an ATP-competitive and highly specific HSP90α/HSP90β inhibitor (Kis: 34.7 nM and 21.3 nM, respectively).</p>Formule :C25H26N8ODegré de pureté :99.22% - 99.49%Couleur et forme :SolidMasse moléculaire :454.53Monastrol
CAS :<p>Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.</p>Formule :C14H16N2O3SDegré de pureté :98.02% - 98.59%Couleur et forme :SolidMasse moléculaire :292.35Ζ-Stat
CAS :<p>ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis in</p>Formule :C10H8O10S3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :384.36Mitoxantrone
CAS :<p>Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.</p>Formule :C22H28N4O6Degré de pureté :96.29% - 98.74%Couleur et forme :Blue PowderMasse moléculaire :444.48GLPG0187
CAS :<p>GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).</p>Formule :C29H37N7O5SDegré de pureté :99.4% - 99.70%Couleur et forme :SolidMasse moléculaire :595.71Chelerythrine chloride
CAS :<p>Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to</p>Formule :C21H18ClNO4Degré de pureté :95% - 99.19%Couleur et forme :Yellow To Orange SolidMasse moléculaire :383.83Dimethylenastron
CAS :<p>Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.</p>Formule :C16H18N2O2SDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :302.39LP-261
CAS :<p>LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest.</p>Formule :C22H19N3O4SDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :421.47VER-82576
CAS :<p>VER-82576 (NVP-BEP800), a synthetic HSP90β inhibitor (IC50: 58 nM), exhibits >70-fold selectivity against Hsp90 family members Trap-1 and Grp94.</p>Formule :C21H23Cl2N5O2SDegré de pureté :97.31% - 99.85%Couleur et forme :SolidMasse moléculaire :480.41Fasudil hydrochloride
CAS :<p>Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.</p>Formule :C14H18ClN3O2SDegré de pureté :99.54% - ≥95%Couleur et forme :White SolidMasse moléculaire :327.83T807
CAS :<p>T807 (AV-1451) is a novel tracer of tau positron emission tomography (PET).</p>Formule :C16H10FN3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :263.27PF-562271 hydrochloride
CAS :<p>PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK.</p>Formule :C21H20F3N7O3SHClDegré de pureté :97.08%Couleur et forme :SolidMasse moléculaire :543.95R59949
CAS :<p>R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.</p>Formule :C28H25F2N3OSDegré de pureté :97.04%Couleur et forme :SolidMasse moléculaire :489.58PND-1186
CAS :<p>PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).</p>Formule :C25H26F3N5O3Degré de pureté :99.14% - 99.75%Couleur et forme :SolidMasse moléculaire :501.5Natalizumab
CAS :<p>Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.</p>Degré de pureté :98.00%Couleur et forme :LiquidMasse moléculaire :N/APamidronic acid
CAS :<p>Pamidronic acid Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow Mesenchymal Stem Cells</p>Formule :C3H11NO7P2Degré de pureté :97.72%Couleur et forme :SolidMasse moléculaire :235.07(E)-Akt inhibitor-IV
CAS :<p>(E)-Akt inhibitor-IV ((E)-AKTIV) ((E)-AKTIV) is an inhibitor of PI3K-Akt.</p>Formule :C31H29IN4SDegré de pureté :99.74% - 99.9%Couleur et forme :SolidMasse moléculaire :616.56GRGDSP acetate(91037-75-1 free base)
<p>GRGDSP acetate(91037-75-1 free base) is a synthetic linear RGD peptide and is an integrin inhibitor.</p>Formule :C24H41N9O12Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :647.64GSK-923295
CAS :<p>GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).</p>Formule :C32H38ClN5O4Degré de pureté :96.22% - 98.02%Couleur et forme :SolidMasse moléculaire :592.13iRGD peptide
CAS :<p>iRGD peptide: 9-amino acid cyclic compound (CRGDKGPDC), found through phage display in mice with tumors.</p>Formule :C35H57N13O14S2Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :948.04Irigenin
CAS :<p>Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra</p>Formule :C18H16O8Degré de pureté :99.50% - 99.85%Couleur et forme :SolidMasse moléculaire :360.31Tirofiban hydrochloride monohydrate
CAS :<p>Tirofiban（MK383） hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist. Cost-effective and quality-assured.</p>Formule :C22H39ClN2O6SDegré de pureté :98.81% - >99.99%Couleur et forme :White SolidMasse moléculaire :495.07TRC051384
CAS :<p>TRC051384 is a HSP70 inducer that reduces stroke-associated neuronal damage and increases survival in a rat model of transient ischemic stroke.</p>Formule :C25H31N5O4Degré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :465.541,2-Dimyristoyl-sn-glycerol
CAS :<p>1,2-Dimyristoyl-sn-glycerol (1,2-DMG) is able to increase AChE activity by 35-40% at concentrations of 25 micrograms/ml in the parasite S. mansoni..</p>Formule :C31H60O5Degré de pureté :99.96%Couleur et forme :White Powder With LumpsMasse moléculaire :512.81TRC051384 HCl
CAS :<p>TRC051384 is an inducer of heat shock protein Hsp70, activating heat shock factor-1 and enhancing Hsp72 expression in neurons and glial cells.</p>Formule :C25H32ClN5O4Degré de pureté :97.55%Couleur et forme :SolidMasse moléculaire :502.01A-286982
CAS :<p>A 286982 blocks the LFA-1 and ICAM-1 integrin-ligand interaction.</p>Formule :C24H27N3O4SDegré de pureté :97.81%Couleur et forme :SolidMasse moléculaire :453.55FRAX486
CAS :<p>FRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.</p>Formule :C25H23Cl2FN6ODegré de pureté :98.81% - 99.52%Couleur et forme :SolidMasse moléculaire :513.39GNF-2
CAS :<p>GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl.</p>Formule :C18H13F3N4O2Degré de pureté :98.17% - ≥95%Couleur et forme :SolidMasse moléculaire :374.32PRE-084 hydrochloride
CAS :<p>PRE-084 hydrochloride is a selective agonist of σ1(IC50:44 nM, in the sigma receptor assay).</p>Formule :C19H28ClNO3Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :353.88CTX-0294885 hydrochloride
<p>CTX-0294885 hydrochloride inhibits 235 kinases, affects AKT family, and aids in studying kinome-related diseases.</p>Formule :C22H25Cl2N7OCouleur et forme :SolidMasse moléculaire :474.39CW-069
CAS :<p>CW-069 (IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.</p>Formule :C23H21IN2O3Degré de pureté :97.52% - 99.52%Couleur et forme :SolidMasse moléculaire :500.33PKC-θ inhibitor hcl
CAS :<p>PKC-theta inhibitor hcl is a selective PKC-θinhibitor(IC50:12 nM).</p>Formule :C20H26ClF3N6O3Degré de pureté :98.93%Couleur et forme :SolidMasse moléculaire :490.91BIO-1211
CAS :<p>BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 = 2 μM).</p>Formule :C36H48N6O9Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :708.8Tetradecyltrimethylammonium bromide
CAS :<p>Tetradecyltrimethylammonium bromide (MitMAB) is a Dynamin GTPase activity inhibitor and a cationic surfactant with asymmetrical structure.</p>Formule :C17H38BrNDegré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :336.39ZIP acetate(863987-12-6 free base)
<p>ZIP acetate inhibits PKMζ (protein kinase Mζ), affecting LTP maintenance and spatial memory, with an IC50 of 1-2.5 μM.</p>Formule :C92H158N30O19Degré de pureté :94.68%Couleur et forme :SolidMasse moléculaire :1988.43α2β1 Integrin Ligand Peptide acetate
<p>α2β1 Integrin Ligand Peptide acetate (α2β1 Integrin Ligand Peptide acetate (134580-64-6)) is a potential antagonist of α2β1 integrin receptor.</p>Formule :C16H26N4O11Degré de pureté :98.46%Couleur et forme :SolidMasse moléculaire :450.4NSC45586
CAS :<p>NSC45586 is a protein phosphatase PHLPP inhibitor, which is selective for PHLPP1 and PHLPP2.</p>Formule :C20H18N6NaO3Degré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :413.4K858 (Racemic)
CAS :<p>K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.</p>Formule :C13H15N3O2SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :277.34GW406108X(Z/E)
CAS :<p>GW406108X(Z/E) is a mixture of different configurations of GW406108X, which is an inhibitor of Kinesin-12 and ULK1 .</p>Formule :C20H11Cl2NO4Degré de pureté :98.23%Couleur et forme :SolidMasse moléculaire :400.21CTX-0294885
CAS :<p>CTX-0294885, a bisanilino pyrimidine, inhibits many kinases; used for Sepharose-based kinase capture.</p>Formule :C22H24ClN7ODegré de pureté :98.73% - ≥95%Couleur et forme :SolidMasse moléculaire :437.93Valecobulin
CAS :<p>Valecobulin is a potent β-tubulin polymerization inhibitor. Valecobulin is a valine prodrug of (S516) and an avascular disrupting compound.</p>Formule :C26H28N6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :536.6SEW2871
CAS :<p>SEW 2871 is an orally available, highly selective S1P1 agonist. It activates ERK, Akt and Rac signaling pathways and induces S1P1 internalization and recycling.</p>Formule :C20H10F6N2OSDegré de pureté :99.96%Couleur et forme :White SolidMasse moléculaire :440.36PF-04691502
CAS :<p>PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.</p>Formule :C22H27N5O4Degré de pureté :96.27% - ≥95%Couleur et forme :SolidMasse moléculaire :425.48SU6656
CAS :<p>SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.</p>Formule :C19H21N3O3SDegré de pureté :98.21% - 98.73%Couleur et forme :SolidMasse moléculaire :371.45Tau protein (592-597), Human TFA
<p>Tau protein (592-597), Human (TFA) is a peptide fragment of human Tau protein.</p>Formule :C36H63F3N10O11Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :868.94Cadherin Peptide, avian Acetate
<p>Cadherin Peptide, avian Acetate: a type-1 transmembrane protein sequence LRAHAVDVNG-NH2.</p>Formule :C46H79N17O15Degré de pureté :97.69%Couleur et forme :SolidMasse moléculaire :1110.22Rebastinib
CAS :<p>DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,</p>Formule :C30H28FN7O3Degré de pureté :99.53% - 99.79%Couleur et forme :SolidMasse moléculaire :553.59Benproperine phosphate
CAS :<p>Benproperine phosphate (Pirexyl phosphate) is a cough suppressant.</p>Formule :C21H30NO5PDegré de pureté :99.84%Couleur et forme :PowderMasse moléculaire :407.44HSP70-IN-1
CAS :<p>HSP70-IN-1 is a heat shock protein (HSP) inhibitor and inhibits the growth of Kasumi-1 cells (IC50: 2.3 μM).</p>Formule :C24H28N6O2SDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :464.58HSDVHK-NH2 acetate
<p>P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).</p>Formule :C32H52N12O11Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :780.39Bisindolylmaleimide I
CAS :<p>Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.</p>Formule :C25H24N4O2Degré de pureté :98.19% - 98.75%Couleur et forme :Orange SolidMasse moléculaire :412.48Valrubicin
CAS :<p>Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.</p>Formule :C34H36F3NO13Degré de pureté :98.63%Couleur et forme :SolidMasse moléculaire :723.644-Isopropoxybenzoic acid
CAS :<p>4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.</p>Formule :C10H12O3Degré de pureté :99.88%Couleur et forme :White To Off-White PowderMasse moléculaire :180.2Rotigaptide TFA(355151-12-1 free base)
<p>Rotigaptide TFA is a Cx43 modulator & AAP that maintains gap junctions & cell communication under stress.</p>Formule :C30H40F3N7O11Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :731.67Parbendazole
CAS :<p>Parbendazole (SKF 29044) is a potent inhibitor of microtubule assembly(EC50 : 8.79 nM).Parbendazole is a carbamate ester-amine.</p>Formule :C13H17N3O2Degré de pureté :99.60%Couleur et forme :Physical Description Crystals Or Fine White Powder (Ntp 1992)Masse moléculaire :247.29Cucurbitacin B
CAS :<p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>Formule :C32H46O8Degré de pureté :97.1% - 99.33%Couleur et forme :SolidMasse moléculaire :558.7SB-743921 hydrochloride
CAS :<p>SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).</p>Formule :C31H34Cl2N2O3Degré de pureté :95.58% - 99.70%Couleur et forme :SolidMasse moléculaire :553.52KY-02327
CAS :<p>KY-02327: Stabilized KY-02061 analog, inhibits Dvl-CXXC5, activates Wnt/β-catenin, and promotes osteoblast differentiation.</p>Formule :C20H27N3O4Degré de pureté :97.04%Couleur et forme :SolidMasse moléculaire :373.45Wiskostatin
CAS :<p>Wiskostatin selectively inhibits N-WASP, key in actin polymerization, linked to Wiskott-Aldrich Syndrome.</p>Formule :C17H18Br2N2ODegré de pureté :99.84% - 99.97%Couleur et forme :White SolidMasse moléculaire :426.15AG1024
CAS :<p>AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).</p>Formule :C14H13BrN2ODegré de pureté :98% - 99.37%Couleur et forme :SolidMasse moléculaire :305.17DTHIB
CAS :<p>DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.</p>Formule :C13H9ClFN3O3Degré de pureté :98.86% - 99.29%Couleur et forme :SolidMasse moléculaire :309.68Cilengitide
CAS :<p>Cilengitide (EMD 121974) is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free assays); ~10-fold selectivity against gpIIbIIIa.</p>Formule :C27H40N8O7Degré de pureté :98% - 99.8%Couleur et forme :SolidMasse moléculaire :588.66Questiomycin A
CAS :<p>Questiomycin A: crème fraiche antibiotic with antibacterial, anticancer effects; inhibits GRP78.</p>Formule :C12H8N2O2Degré de pureté :98.13% - 98.7%Couleur et forme :SolidMasse moléculaire :212.2Teprenone
CAS :<p>Teprenone (Geranylgeranylacetone) is a anti-ulcer drug, and works as an inducer of heat shock proteins (HSPs).</p>Formule :C23H38ODegré de pureté :99.1% - 99.96%Couleur et forme :SolidMasse moléculaire :330.55Afuresertib
CAS :<p>Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic</p>Formule :C18H17Cl2FN4OSDegré de pureté :97.51% - 99.51%Couleur et forme :SolidMasse moléculaire :427.32Vevorisertib
CAS :<p>Vevorisertib (ARQ 751) is an orally active, potent and selective pan-AKT serine/threonine kinase inhibitor with inhibitory effects on AKT1/AKT2/AKT3.</p>Formule :C35H38N8ODegré de pureté :98.88%Couleur et forme :SolidMasse moléculaire :586.73SC79
CAS :<p>SC79 is an AKT agonist with specificity and blood-brain barrier permeability.</p>Formule :C17H17ClN2O5Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :364.78FRAX1036
CAS :<p>FRAX-1036 is a effective and selective PAK1 inhibitor.</p>Formule :C28H32ClN7ODegré de pureté :97.66% - 98.67%Couleur et forme :SolidMasse moléculaire :518.05Nocodazole
CAS :<p>Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.</p>Formule :C14H11N3O3SDegré de pureté :98% - 99.91%Couleur et forme :Physical Description White Powder (Ntp 1992)Masse moléculaire :301.32G-5555 hydrochloride
<p>G-5555 hydrochloride is a potent and selective inhibitor of PAK1 (Ki: 3.7 nM).</p>Formule :C25H26Cl2N6O3Couleur et forme :SolidMasse moléculaire :529.42CEP-37440
CAS :<p>CEP-37440 is an effective and specific Dual FAK/ALK inhibitor with IC50s of 120 nM(ALK cellular in 75% human plasma) and 2.3 nM (FAK).</p>Formule :C30H38ClN7O3Degré de pureté :98.86% - 99.98%Couleur et forme :SolidMasse moléculaire :580.12Darovasertib
CAS :<p>Darovasertib (LXS196) is a potent PKC inhibitor, orally active, with IC50 of 1.9 nM (PKCα), 0.4 nM (PKCθ), 3.1 μM (GSK3β).</p>Formule :C22H23F3N8ODegré de pureté :98.72% - ≥95%Couleur et forme :SolidMasse moléculaire :472.47Go 6983
CAS :<p>Go 6983 is a PKC inhibitor with IC50 values of 7, 7, 6, 10, and 60 nM for PKCα, PKCβ, PKCγ, PKCδ, and PKCζ, respectively. High-Quality, Low-Cost!</p>Formule :C26H26N4O3Degré de pureté :98.41% - 99.85%Couleur et forme :SolidMasse moléculaire :442.51Bisindolylmaleimide IV
CAS :<p>Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)</p>Formule :C20H13N3O2Degré de pureté :98.83%Couleur et forme :Dark Red SolidMasse moléculaire :327.34Asciminib
CAS :<p>Asciminib (ABL001) (ABL001) is a potent and selective Bcr-Abl inhibitor (Kd: 0.5–0.8nM).</p>Formule :C20H18ClF2N5O3Degré de pureté :98.82% - 99.70%Couleur et forme :SolidMasse moléculaire :449.84Olverembatinib dimesylate
CAS :<p>Olverembatinib dimesylate (GZD824 Dimesylate) is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I).</p>Formule :C29H27F3N6O·2CH4O3SDegré de pureté :97.66% - >99.99%Couleur et forme :SolidMasse moléculaire :724.77FRAX597
CAS :<p>FRAX597 is an effective, ATP-competitive inhibitor of group I PAKs, and for PAK1(IC50=8 nM), PAK2(IC50=13 nM), and PAK3 (IC50=19 nM).</p>Formule :C29H28ClN7OSDegré de pureté :97.34% - 99.85%Couleur et forme :SolidMasse moléculaire :558.1GPRP acetate (67869-62-9 free base)
CAS :<p>GPRP acetate (Pefabloc FG) is fibrinogen-related peptides, which inhibit the interaction of fibrinogen with the platelet membrane glycoprotein IIbIIIa complex.</p>Formule :C20H35N7O7Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :485.53PF-04929113 Mesylate
CAS :<p>PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37</p>Formule :C26H34F3N5O7SDegré de pureté :99% - 99.46%Couleur et forme :SolidMasse moléculaire :617.63PF-562271 besylate
CAS :<p>PF-562271 besylate: potent, ATP-competitive FAK inhibitor, IC50 1.5 nM, 10x less effective on Pyk2, highly selective vs other kinases.</p>Formule :C21H20F3N7O3S·C6H6O3SDegré de pureté :97.65% - 99.01%Couleur et forme :SolidMasse moléculaire :665.66Danegaptide Hydrochloride
CAS :<p>Danegaptide Hydrochloride (GAP-134 (Hydrochloride)) (GAP-134 Hydrochloride) is a selective modifier of the gap junction protein.</p>Formule :C14H18ClN3O4Degré de pureté :99.55%Couleur et forme :SolidMasse moléculaire :327.76Chelerythrine
CAS :<p>1.</p>Formule :C21H18NO4Degré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :348.37Bafetinib
CAS :<p>Bafetinib (INNO-406): Dual Bcr-Abl/Lyn inhibitor; IC50: 5.8/19 nM; ineffective against T315I mutant, less on c-Kit/PDGFR.</p>Formule :C30H31F3N8ODegré de pureté :94.16% - 99.68%Couleur et forme :SolidMasse moléculaire :576.62BGG463
CAS :<p>BGG463 (K 0859) can inhibit c-ABL-T334I, BCR-ABL and BCR-ABL-T315I variants with an IC50 of 0.25 μM, 0.09 μM and 0.590 μM, respectively.</p>Formule :C30H29F3N6O3Degré de pureté :95.05% - >99.99%Couleur et forme :SolidMasse moléculaire :578.58Miransertib
CAS :<p>Miransertib (ARQ-092) is an orally bioavailable, selective, and potent allosteric Akt inhibitor.</p>Formule :C27H24N6Degré de pureté :99.85% - ≥95%Couleur et forme :SolidMasse moléculaire :432.52GNF-5
CAS :<p>GNF-5, non-ATP Bcr-Abl inhibitor (IC50: 0.22±0.1 uM, wild-type), improves upon GNF-2 with better pharmacokinetics.</p>Formule :C20H17F3N4O3Degré de pureté :98% - 99.94%Couleur et forme :SolidMasse moléculaire :418.37Arg-Gly-Asp TFA (99896-85-2(free base))
<p>Arg-Gly-Asp TFA (RGD, 99896-85-2) is a tripeptide that promotes cell adhesion and integrin binding.</p>Formule :C14H23F3N6O8Degré de pureté :99.2% - ≥98%Couleur et forme :SolidMasse moléculaire :460.36DDO-5936
CAS :<p>DDO-5936 is a potent and specific HSP90-Cdc37 PPI inhibitor.</p>Formule :C25H29N5O4SDegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :495.59Taurochenodeoxycholic Acid
CAS :<p>Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.</p>Formule :C26H45NO6SDegré de pureté :99.53% - 99.86%Couleur et forme :SolidMasse moléculaire :499.7ATM-3507 trihydrochloride
CAS :<p>ATM-3507 trihydrochloride, a potent inhibitor of tropomyosin, demonstrates inhibition concentration (IC50) values ranging from 3.83 to 6.84 μM across various</p>Formule :C37H49Cl3FN5O2Couleur et forme :SolidMasse moléculaire :721.17AG957
CAS :<p>Tyrphostin AG957, a tyrosine kinase inhibitor with anti-BCR/ABL tyrosine kinase activity restores beta1 integrin-mediated adhesion and inhibitory signaling in</p>Formule :C15H15NO4Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :273.28p5 Ligand for Dnak and DnaJ acetate
<p>p5 Ligand for Dnak and DnaJ acetate is a nonapeptide. It is a high-affinity ligand for DnaK (E. coli Hsp70) and DnaJ (E. coli Hsp40).</p>Formule :C46H85N15O13SDegré de pureté :96.33%Couleur et forme :SolidMasse moléculaire :1088.32Mps1-IN-3 hydrochloride
<p>Mps1-IN-3 HCl: potent Mps1 inhibitor (IC50: 50 nM), hampers glioblastoma growth, enhances vincristine efficacy in vivo.</p>Formule :C26H32ClN7O4SCouleur et forme :SolidMasse moléculaire :574.09Daphnoretin
CAS :<p>1.</p>Formule :C19H12O7Degré de pureté :98% - 99.85%Couleur et forme :SolidMasse moléculaire :352.29Cyclo(-RGDfK)
CAS :<p>Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.</p>Formule :C27H41N9O7Degré de pureté :95.29% - >99.99%Couleur et forme :SolidMasse moléculaire :603.67
