
Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1503 produits trouvés pour "Signalisation du cytosquelette"
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HS-345
CAS :HS-345, a TrkA/Akt inhibitor, exhibits potent anti-pancreatic cancer properties. This compound inhibits the growth and proliferation of pancreatic cancer cells by blocking the TrkA/Akt signaling pathway and induces cell apoptosis (Apoptosis). Additionally, HS-345 inhibits angiogenesis by reducing the expression of HIF-1α and VEGF. It holds promise for use in pancreatic cancer research.Formule :C19H18N6O2SCouleur et forme :SolidMasse moléculaire :394.45Tubulin polymerization-IN-33
Tubulin-IN-33, an oxazoloisoindole, hinders microtubule assembly; effective against NCI cancer cells.Formule :C27H28N2O6Couleur et forme :SolidMasse moléculaire :476.52Macbecin I
CAS :Hsp90 inhibitorFormule :C30H42N2O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :558.66Tubulin polymerization-IN-74
CAS :Tubulin polymerization-IN-74 (compound 11) is an inhibitor of tubulin polymerization, with an IC50 value of 15 μM. It is applicable to cancer research.Formule :C14H11NSCouleur et forme :SolidMasse moléculaire :225.309MT-134
MT-134 is a SkMII -specific inhibitor and has excellent exposure in muscles.Formule :C19H16N4O3Couleur et forme :SolidMasse moléculaire :348.36KU-32
CAS :KU-32 is a novel and novobiocin-based Hsp90 inhibitor. It can protect against neuronal cell death.Formule :C20H25NO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :407.41SR121566A
CAS :SR121566A is a novel non-peptide antagonist of Glycoprotein IIb/IIIa (GP IIb-IIIa).Formule :C20H25N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :431.51NRX-1532
NRX-1532 is a small molecule β-catenin:β-TrCP interaction enhancer.Formule :C16H11F3N4O2Degré de pureté :98.95% - 99.94%Couleur et forme :SolidMasse moléculaire :348.28Ref: TM-T61172
1mg147,00€5mg358,00€10mg597,00€25mg1.153,00€50mg1.549,00€100mg2.088,00€500mg4.185,00€1mL*10mM (DMSO)394,00€AKT Kinase Inhibitor
CAS :AKT Kinase Inhibitor is an Akt inhibitor with antitumor activity that selectively inhibits cell proliferation in a dose-dependent manner.Cost-effective and quality-assured.Formule :C16H19N7O3Degré de pureté :97.83% - 99.13%Couleur et forme :SolidMasse moléculaire :357.37Ref: TM-T10276
1mg136,00€5mg329,00€10mg567,00€25mg887,00€50mg1.188,00€100mg1.605,00€1mL*10mM (DMSO)360,00€NRX-103095
CAS :NRX-103095 increases β-catenin binding to SCFβ-TrCP E3 ligase; EC50 is 163 nM for pSer33/Ser37 affinity boost.Formule :C22H16Cl2F3N3O3SDegré de pureté :99.85% - 99.95%Couleur et forme :SolidMasse moléculaire :530.35Ref: TM-T63730
1mg142,00€5mg344,00€10mg557,00€25mg1.108,00€50mg1.783,00€100mg2.673,00€1mL*10mM (DMSO)404,00€NRX-252114
CAS :NRX-252114 promotes mutant β-catenin degradation, binding it to E3 ligase SCFβ-TrCP (EC50: 6.5 nM; Kd: 0.4 nM).Formule :C22H12Cl2F3N3O2SDegré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :510.32INS018 055
CAS :INS018 055 (TNIK&MAP4K4-IN-2) is a TNIK and MAP4K4 inhibitor with anti-fibrotic activity.Formule :C27H30FN7ODegré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :487.57NRX-103094
CAS :NRX-103094 boosts β-catenin binding to SCFβ-TrCP ligase with EC50 62 nM and Kd 0.6 nM.Formule :C20H11Cl2F3N2O4SDegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :503.28Ombrabulin
CAS :Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells.Formule :C21H26N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :402.44Sevasemten
CAS :Sevasemten is an allosteric inhibitor that targets skeletal muscle myosin. It displays selectivity in its inhibition, demonstrated by IC50 values of ≤10 μM for skeletal muscle myosin and >100 μM for cardiac myosin, respectively.Formule :C16H11F4N5O2Couleur et forme :SolidMasse moléculaire :381.28ZW4864
CAS :ZW4864 is a selective inhibitor of the β-catenin/B-Cell Lymphoma 9 protein (β-catenin/BCL9 PPI) interaction, demonstrating oral activity. It inhibits β-catenin/BCL9 PPI with a K_i value of 0.76 μM and an IC_50 value of 0.87 μM.Formule :C33H43ClN6O3Couleur et forme :SolidMasse moléculaire :607.2Cercosporin
CAS :Cercosporin, produced by the plant pathogen Cercospora kikuchii and the elsinochromes, is a potent photosensitizer with a short activation wavelength. Cercosporin contains perylene quinone structural features essential for PKC activity (IC50: 0.6-1.3 μM).Formule :C29H26O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :534.51Methyl (6-chloro-1H-benzo[d]imidazol-2-yl)carbamate
CAS :Methyl (6-chloro-1H-benzo[d]imidazol-2-yl)carbamate is a useful organic compound for research related to life sciences. The catalog number is T65302 and the CAS number is 20367-38-8.Formule :C9H8ClN3O2Couleur et forme :SolidMasse moléculaire :225.6324-Methylenecycloartanyl ferulate
CAS :24-Methylenecycloartanyl ferulate, a compound belonging to the γ-oryzanol family, demonstrates the ability to enhance parvin-beta expression within human breast cancer cells. Furthermore, it exhibits potential as an ATP-competitive Akt1 inhibitor, with an EC 50 value of 33.3 μM.Formule :C41H60O4Couleur et forme :SolidMasse moléculaire :616.927Tau tracer 2
CAS :Tau tracer 2 (Pl-2620) is a specific imaging agent designed to detect and visualize Tau protein aggregates, primarily used for diagnosing neurodegenerative diseases [1].Formule :C15H9FN4Couleur et forme :SolidMasse moléculaire :264.263

