Composés deutérés

Applications 1,2,3,5-Tetra-O-acetyl β-D-Ribofuranose-13C5 is an intermediate used in the synthesis of Ribavirin-13C5 (R414477), which is a labeled Rivavirin. Purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research.
References Fernandez, H., et al.: Eur. J. Epidemiol., 2, 1 (1986), Liao, H.J. and Stollar, V.: Antiviral Res., 22, 285 (1993), Honda, Y., et al.: Antimicrob. Agents Chemother., 38, 653 (1994), Reichard, O., et al.: Lancet, 351, 83 (1998)

Applications Harpagoside-D5 is an isotope labelled analog of Harpagoside (H105275). Harpagoside is an iridoid glycoside along with with Harpagide (H105270), the potential to be strong anti-inflammatory agents providing the bulk of the observed effects from their plant origins.
References Zhang, L. et al.: Bioorg Med. Chem., 19, 4882 (2011); Wen, B. et al.: J. Ethnopharm., 147, 503 (2013);

Applications Bromobenzene-2,4,6-d3 (CAS# 13122-41-3) is a useful isotopically labeled research compound.

Applications n-Hexyl-1,1-d2 Alcohol (CAS# 52598-04-6) is a useful isotopically labeled research compound.

Applications 9-Methylanthracene-d12 (CAS# 6406-97-9) is a useful isotopically labeled research compound.

Applications Isotope labelled wittig reagent.

Applications (±)-Phenyramidol-d4 is a muscle relaxant drug. It can also be used in analytical study of LC-MS method development on α1-acid glycoprotein-based stationary phase for resoln. and screening of enantiomers by HPLC.
References Michishita, T., et al.: J Sep Sci, 33, 3627 (2010)

Applications 1,10-Phenanthroline-d8 (CAS# 90412-47-8) is a useful isotopically labeled research compound.

Applications 4-Isothioureidobutyronitrile-13C2, 15N3 Hydrochloride acts as a reagent in the synthesis of nitrile derivatives and their pharmaceutical uses and compositions.
References Menon, K., et al.: PCT Int. Appl. (2010), WO 2010135170 A2 20101125

Applications 1-Bromotetradecane-d29 is the isotope labelled analog of 1-Bromotetradecane (B688015); a compound that is part of a group of bromoalkanes that have high potential to cause allergic contact dermatitis (ACD) in humans. 1-Bromotetradecane is also a useful synthetic intermediate.
References Basketter, D., et al.: Contact Dermatitis, 27, 137 (1992); Fedorowicz, A., et al.: Chem. Res. Toxicol., 18, 954 (2005); Siegel, P., et al.: Toxicol. Sci., 107, 78 (2009)

Applications 2-Tetradecylcyclobutanone-D29 is a labelled analogue of 2-Tetradecylcyclobutanone (T291540).

Applications (±)-2-Ethylhexyl-d17 Acetate (CAS# 1219802-70-6) is a useful isotopically labeled research compound.

Applications 4-Hydroxypiperidine-D4 is an isotope labelled form of 4-Hydroxypiperidine (H950845), a reagent for the synthesis of acridine (A190900) derivatives and fibrinogen receptor antagonists.
References Yang, D. et al.: Macromol., 35, 5304 (2002); Harrison, R.J. et al.: Bioorg. Med. Chem. Lett., 9, 2463 (1999);