Composés deutérés

Applications Ethyl 2-(3-((1R,3R)-3-(((R)-2-(3-Chlorophenyl)-2-hydroxyethyl)amino)cyclohexyl)phenoxy)acetate-d5 is a labeled analogue of Ethyl 2-(3-((1R,3R)-3-(((R)-2-(3-Chlorophenyl)-2-hydroxyethyl)amino)cyclohexyl)phenoxy)acetate which is used in the preparation of phenylethanolamine compounds as β3-agonists.

Applications n-Butyl-4,4,4-d3-benzene (CAS# 109232-94-2) is a useful isotopically labeled research compound.

Applications 4-n-Pentylphenol-2,3,5,6-d4,OD (CAS# 126839-95-0) is a useful isotopically labeled research compound.

Applications 2-Propane-d7-thiol (CAS# 1219803-56-1) is a useful isotopically labeled research compound.

Applications Labelled 3-(Methylnitrosamino)propionitrile (MNPN) (M325715). It was detected for the 1st time in the saliva of betel quid chewers and is a potent carcinogen.
References Bartsch, H., et al.: Mutat. Res., 250, 103 (1991), Su, T., et al.: Drug Metab. Dispos., 24, 884 (1996), Guengerich, F., et al.: Chem. Res. Toxicol., 14, 611 (2001),

Applications Sodium Propionate-d5 (CAS# 202529-18-8) is a useful isotopically labeled research compound.

Applications Isotope labelled analogue of D-Allose (A548006) is a rare naturally occurring monosaccharide, known to exert anti-proliferative effects on cancer cells.
References Jeong, R.U., et al.: Anal. Bioanal. Chem., 401, 689 (2011); Yamada, K., et al.: Nut. Res., 32, 116 (2012);

Applications rac-trans-N-Desmethyl Sertraline-d3 Hydrochloride is deuterium labelled rac-trans-N-Desmethyl Sertraline Hydrochloride (D292117), which is a metabolite of Sertraline. rac-trans-N-Desmethyl Sertraline-d3 Hydrochloride can be used for treating CNS disorders.
References Welch, W.M., et al.: J. Med. Chem. 27, 1508 (1984)

Applications Cyclopropane-1-d1-carboxylic Acid (CAS# 19136-94-8) is a useful isotopically labeled research compound.

Applications Ammonium hydrogen phosphate-15N is the labelled analogue of Ammonium hydrogen phosphate (CAS:7722-76-1), a reagent that is useful for organic synthesis.

Applications p-Tolyl-d7 Isocyanate (CAS# 1219798-59-0) is a useful isotopically labeled research compound.

Applications Isotope labelled Cyclopropylmethyl Bromide is a reagent used in the synthesis of human dihydroorotate dehydrogensase inhibitors which are based on azole scaffolds. In addition it is used in the preparation of ([11C]CMDC) for PET imaging of mGlur2 which has been a proposed target in the treatment of schizophrenia.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sainas, S. et al.: Eur. J. Med. Chem., 129, 287 (2017); Ma, Y. et al.: Bioorg. Med. Chem., 25, 1014 (2017);

Applications L-4-Hydroxyphenyl-2,6-d2-alanine (CAS# 57746-15-3) is a useful isotopically labeled research compound.

Applications 4'-Chloroacetophenone-2',3',5',6'-d4 (CAS# 284474-50-6) is a useful isotopically labeled research compound.

Applications TRIS Maleate-d15 (CAS# 1219806-43-5) is a useful isotopically labeled research compound.

Applications Acetylcholine-1,1,2,2-d4 Bromide is the deuterium labelled form of Acetylcholine Bromide (A172073), which is an endogenous neurotransmitter at cholinergic synapses.
References Kobayashi, M., et al.: Adv. Physiol. Sci., 22, 319 (1981); Hulme, C., et al.: Biophys. J., 91, 2371 (2006);

Applications 3-Amino-1-propanol-d6 is a deuterated version of 3-Amino-1-propanol (A628130) which is used in the synthesis of tetrathiafulvalenes displaying optical and electrochemical properties. Also used in the synthesis of lipid-like materials for the delivery and encapsulation of RNAi therapeutics.
References Ignatenko, E. et al.: Russ. J. Org. Chem., 49, 1379 (2013); Akinc, A. et al.: Nat. Biotech., 26, 561 (2008);