
Toxicologie
13573 produits trouvés pour "Toxicologie"
2-Amino-6-methylpyrimidin-4(3H)-one
CAS :Produit contrôléApplications 2-Amino-6-methylpyrimidin-4(3H)-one (cas# 3977-29-5) is a useful research chemical.
Formule :C5H7N3OCouleur et forme :NeatMasse moléculaire :125.13Beclomethasone 17-Propionate
CAS :Impurity Beclomethasone Dipropionate EP Impurity H
Applications Beclomethasone 17-Propionate (Beclomethasone Dipropionate EP Impurity H) is an active metabolite of Beclomethasone Dipropionate (BDP).
References Soria, I., et al.: Biopharm. Drug Dispos., 19, 297 (1998), Harrison, L., et al., J. Pharm. Pharmacol., 51, 1235 (1999), Daley-Yates, P., et al.: Br. J. Clin. Pharm., 51, 400 (2001).Formule :C25H33ClO6Couleur et forme :WhiteMasse moléculaire :464.983-Sulfo-glycodeoxycholic Acid Disodium Salt
CAS :Produit contrôléFormule :C26H41NNa2O8SCouleur et forme :NeatMasse moléculaire :573.65α-Propyl-α-(1-demethylethyl)-Verapamil Hydrochloride
CAS :Produit contrôléApplications α-Propyl-α-(1-demethylethyl)-Verapamil is an impurity of Verapamil (V125000, HCl salt) which is a calcium channel blocker.
References Atlas, D, and Adler, M.: Proc. Natl. Acad. Sci. USA, 78, 1237 (1981), Janis, R., et al.: Adv. Drug. Res., 16, 309 (1987)Formule :C27H38N2O4·ClHCouleur et forme :NeatMasse moléculaire :491.06L-Lysine Clonixinate
CAS :Applications L-Lysine Clonixinate is a non-morphinic andalgesic.
References Krymchantowski, A., et al.: Curr. Ther. Res., 64, 505 (2003), Di Girolamo, G., et al.: Brit. J. Pharmacol., 141, 1234 (2004),Formule :C13H11ClN2O2·C6H14N2O2Couleur et forme :Off WhiteMasse moléculaire :408.88Octylonium-d3 Bromide
CAS :Produit contrôléApplications Labelled Octylonium Bromide (O293250). Octylonium bromide is an antimuscarinic. Octylonium bromide is a platelet-activating factor antagonist as analgesic, anti-inflammatory, uterine contraction inhibiting, and anti-tumor agent. Octylonium bromide is used as an antispasmodic.
References Manzini, S., et al.: Drugs Exp. Clin. Res., 14, 265 (1988), Emonds-Alt, X., et al.: Eur. J. Pharmacol., 250, 403 (1993), Sutton, J., et al.: Eur. J. Clin. Pharmacol., 52, 365 (1997), Catalioto, R., et al.: Br. J. Pharmacol., 123, 81 (1998),Formule :C29H40D3BrN2O4Couleur et forme :NeatMasse moléculaire :566.59Thiacloprid-d4
CAS :Produit contrôléStability Hygroscopic
Applications Thiacloprid-d4 is the isotope labelled analog of Thiacloprid, which is a chloronicotinyl insecticide for use in fruits and vegetables.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Nauen, R., et al.: Pestic. Sci., 53, 133 (1998), Jetter, R., et al.: Plant Physiol., 126, 1725 (2001), Weichert, H., et al.: J. Agric. Food Chem., 54, 6294 (2006), Hoffmann, E., et al.: J. Insect. Sci., 8 (2008),Formule :C102H4H5ClN4SCouleur et forme :Off WhiteMasse moléculaire :256.7517β-Dihydro Equilin 3-Sulfate Sodium Salt
CAS :Stability Hygroscopic
Applications A metabolite of Equilin (E592800).
References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),Formule :C18H21O5S·NaCouleur et forme :NeatMasse moléculaire :372.41Bentazepam
CAS :Produit contrôléStability Hygroscopic
Applications Bentazepam is a thienodiazepine which is a benzodiazepine analog. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties.
References Gonzalez Lopez, F., et al.; Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 482 (1986); Marino, E., et al.: Int. J. Clin. Pharmacol. Ther. Toxicol., 25, 627 (1987)Formule :C17H16N2OSCouleur et forme :NeatMasse moléculaire :296.39Methotrexate (1 mg/mL in Methanol with 0.1N NaOH)
CAS :Formule :C20H22N8O5Couleur et forme :Single SolutionMasse moléculaire :454.44Methyltriphenylphosphonium Bromide
CAS :Applications Methyltriphenylphosphonium Bromide is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.
References Selassie, C.D. et al.: J. Med. Chem., 33, 1914 (1990); Venkatachalam, M.A et al.: Kidney Int., 49, 449 (1996);Formule :C19H18P·BrCouleur et forme :Off-WhiteMasse moléculaire :357.22Celecoxib Carboxylic Acid
CAS :Produit contrôléFormule :C17H12F3N3O4SCouleur et forme :Off WhiteMasse moléculaire :411.36Diphenhydramine N-Oxide
CAS :Stability Hygroscopic
Applications A metabolite of Diphenhydramine (D486900) in humans.
References Breyer-Pfaff, U., et al.: Drug Metab. Dispos., 25, 340 (1997),Formule :C17H21NO2Couleur et forme :NeatMasse moléculaire :271.35Captafol
CAS :Produit contrôléFormule :C10H9Cl4NO2SCouleur et forme :ColourlessMasse moléculaire :349.064-Hydroxy Propofol 1-O-β-D-Glucuronide Sodium Salt
Produit contrôléFormule :C18H25NaO8Couleur et forme :NeatMasse moléculaire :392.376Betamethasone 21-Propionate
CAS :Produit contrôléImpurity Clobetasol Propionate EP Impurity K / Betamethasone Dipropionate EP Impurity C
Applications Betamethasone 21-Propionate (Clobetasol Propionate EP Impurity K) is a degradation product of Betamethasone. Glucocorticoid.
References Andersson, P., et al.: J. Pharm. Pharmacol., 36, 763 (1984), Wurthwein, G., et al.: Biopharm. Drug Dispos., 11, 381 (1990), Samtani, M., et al.: J. Pharm. Sci., 93, 726 (2004), Samtani, M., et al.: Drug Metab. Dispos., 33, 1124 (2005),Formule :C25H33FO6Couleur et forme :Off-WhiteMasse moléculaire :448.52Pipamazine
CAS :Applications Pipamazine is a drug od the phenothiazine class which used to be used as an antiemetic.
References Bhargava, K. et al.: Br. J. Pharmacol. Chemother., 22, 154 (1964); Bhargava, K. et al.: Br. J. Pharmacol. Chemother., 21, 436 (1963);Formule :C21H24ClN3OSCouleur et forme :NeatMasse moléculaire :401.95Guazatine Sesquisulfate Salt
CAS :Formule :C18H41N7·5(H2SO4)Couleur et forme :NeatMasse moléculaire :502.69N-Desmethyl Rosuvastatin-d6 Disodium Salt
CAS :Produit contrôléApplications Inhibits the enzyme HMG-CoA reductase in vitro.
References Endo, A., et al.: J. Antibiot., 32, 852 (1979), Alberts, A.W., et al.: Drug Invest., 2 (Suppl. 2), 9 (1990), Kuroda, M., et al.: Biochim. Biophys. Acta, 486, 70 (1977),Formule :C21H18D6FN3Na2O6SCouleur et forme :NeatMasse moléculaire :517.51Fenbufen-d9
CAS :Produit contrôléApplications Anti-inflammatory.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Becker, A., et al.: J. Int. Med. Res., 8, 333 (1980), Child, R.G., et al.: Arzneim.-Forsch., 30, 695 (1980), Bolte, H.F., et al.: Arzneim.-Forsch., 30, 721 (1980).Formule :C16H5D9O3Couleur et forme :NeatMasse moléculaire :263.34Disperse Blue 56 (Technical Grade)
CAS :Produit contrôléFormule :C14H9ClN2O4Couleur et forme :NeatMasse moléculaire :304.6856α-Chloro-17-acetoxy Progesterone
CAS :Applications Progesterone (P755900) impurity.
References Liang, T., et al.: Biol. Chem., 256, 7998 (1981), Bratoeff, E., et al.: J. Steroid Biochem. Mol. Biol., 111, 275 (2008),Formule :C23H31ClO4Couleur et forme :NeatMasse moléculaire :406.94(5α)-Androst-2-en-17-one, 90%
CAS :Produit contrôléApplications Metabolite of 5α-Androst-16-en-3β-ol
References Gower, D., et al.: J. Steroid Biochem. Mol. Biol., 63, 81 (1997), Zorko, M., et al.: Steroids, 65, 46 (2000), Diel, P., et al.: Toxicol. Lett., 169, 64 (2007),Formule :C19H28ODegré de pureté :90%Couleur et forme :NeatMasse moléculaire :272.423-Sulfoglycolithocholic Acid Disodium Salt
CAS :Produit contrôléStability Hygroscopic
Applications 3-Sulfoglycolithocholic Acid Disodium Salt is a derivative of Lithocholic acid (L469180). Lithocholic acid (LCA) is a putative tumor promoter,that is shown to be able to inhibit mammalian DNA polymerase β.
References Ogawa, A., et al.: Jap. J. Canc. Res., 89, 1154 (1998)Formule :C26H41NO7S·2NaCouleur et forme :NeatMasse moléculaire :557.65S-Methyl Fenitrothion
CAS :Produit contrôléStability Moisture Sensitive
Applications S-Methyl Fenitrothion is a metabolite of Fenitrothion (F247850), an insecticide.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Fukushima, M., et. al.: J. Agr. Food Chem., 51, 5016 (2003); Nishizawa, Y., et al.: Agric. Biol. Chem., 25, 605 (1961)Formule :C9H12NO5PSCouleur et forme :NeatMasse moléculaire :277.23b-Cembrenediol
CAS :Produit contrôléStability Light Sensitive
Applications β-Cembrenediol is an inhibitor of tumor promotion. Novel c-Met inhibitors which are used in anticancer treatments.
References Le-Huu, P. et al.: ChemCatChem., 8, 3755 (2016); Ebrahim, H. et al.: Bioorg. Med. Chem., 24, 5748 (2016);Formule :C20H34O2Couleur et forme :Off-WhiteMasse moléculaire :306.482,3,3-Trichloro-2-propenesulfonic Acid Sodium Salt
CAS :Produit contrôléFormule :C3H2Cl3O3S·NaCouleur et forme :NeatMasse moléculaire :247.461,2-Dihydro-Betamethasone 17,21-Dipropionate
CAS :Stability Hygroscopic
Applications A degradation product of Betamethasone (B327000).
References Andersson, P., et al.: J. Pharm. Pharmacol., 36, 763 (1984), Wurthwein, G., et al.: Biopharm. Drug Dispos., 11, 381 (1990), Samtani, M., et al.: J. Pharm. Sci., 93, 726 (2004), Samtani, M., et al.: Drug Metab. Dispos., 33, 1124 (2005),Formule :C28H39FO7Couleur et forme :NeatMasse moléculaire :506.6Metoprine
CAS :Stability Hygroscopic
Applications A 2,4-Diaminopyrimidine derivative as antimalarial agent.
References Andersson, K.J.I., et al.: Nature, 143, 720 (1939), Cecil, R., et al.: Biochem.J., et al.: 43, 592 (1948),Formule :C11H10Cl2N4Couleur et forme :NeatMasse moléculaire :269.13Cyclobarbital
CAS :Produit contrôléApplications Cyclobarbital has been used as an anesthetic and sedative. Controlled substance (depressant).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hofrichter, G., et al.: Arzneim.-Forsch., 17, 242 (1967),Formule :C12H16N2O3Couleur et forme :NeatMasse moléculaire :236.27Phosphonomethanol
CAS :Produit contrôléApplications Phosphonomethanol has been used in the investigation on the stereochemistry of 2-Hydroxyethylphosphonate Dioxygenase.
References Whitteck, J.T., et al.: J. Am. Chem. Soc., 133, 4236 (2011); Duca, J.S., et al.: Chem. Materials., 12, 3821 (2000);Formule :CH5O4PCouleur et forme :Off White SolidMasse moléculaire :112.026-Benzylaminopurine
CAS :Produit contrôléApplications 6-Benzylaminopurine can be used as reagent/reactant in pharmacological activity and synthesis preparation for modification of the length and structure of the linker of N6-benzyladenosine modulates its selective antiviral activity against enterovirus 71.
References Drenichev, M., S.: Eur. J. Med. Chem., 111, 84-94 (2016);Formule :C12H11N5Couleur et forme :Off-WhiteMasse moléculaire :225.25tert-Butyl-d9-amine
CAS :Produit contrôléStability Volatile
Applications tert-Butylamine is common reagent in pharmaceuticals syntheses. Used in the preparation of aminoBODIPY compounds for chemical analyses. Also it aids in the synthesis of benzylurea-based insecticides containing amide and sulfonate groups. It has also been used in the synthesis of BPTES analogs, that act as glutaminase inhibitors, which can attenuate the growth of human lymphoma B cells. This is the labeled analog.
E0
References Osorio-Martinez, C. et al.: J. Org. Chem., 77, 5434 (2012); Sun, R. et al.: J. Agri. Food, Chem., 61, 517 (2013); Shukla, K. et al.: J. Med. Chem., 55, 10551 (2012);Formule :C4D9H2NCouleur et forme :NeatMasse moléculaire :82.19(R)-Bicalutamide
CAS :Produit contrôléApplications (R)-Enantiomer of Bicalutamide. Used as an antiandrogen, antineoplastic (hormonal).
References Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993), McKillop, D., et al.: Xenobiotica, 25, 623 (1995),Formule :C18H14F4N2O4SCouleur et forme :WhiteMasse moléculaire :430.37N-Desmethyl Ulipristal Acetate
CAS :Produit contrôléApplications N-Desmethyl Ulipristal Acetate is the N-monodemethylated analogue and metabolite of the selective progesterone receptor modulator Ulipristal Acetate (U700810). N-Desmethyl Ulipristal Acetate contributes significantly to the antiprogestational activity of its parent compound.
References Attardi, B.J. et al.: J. Steroid Biochem. Mol. Biol., 88, 277 (2004);Formule :C29H35NO4Couleur et forme :NeatMasse moléculaire :461.59Quizalofop-P
CAS :Produit contrôléFormule :C17H13ClN2O4Couleur et forme :NeatMasse moléculaire :344.7517-Desacetyl Rocuronium Bromide
CAS :Impurity Rocuronium EP Impurity C
Applications 17-Desacetyl Rocuronium Bromide (Rocuronium EP Impurity C) is a metabolite of Rocuronium (R639500), in human plasma.
References Kleef, U., et al.: J. Chromatogr., 621, 65 (1993), Proost, J., et al.: Br. J. Anaesth., 85, 717 (2000),Formule :C30H51N2O3·BrCouleur et forme :NeatMasse moléculaire :567.64Quinidine-d3
CAS :Produit contrôléApplications A dextrorotatory stereoizomer of Quinine. Antiarrhythmic (class IA). Antimalarial.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Loutfy, M.A., et al.: Anal. Profiles Drug Subs., 12, 483 (1983), Mason, J. W., et al.: Ann. N. Y. Acad. Sci., 432, 162 (1984),Formule :C202H3H21N2O2Couleur et forme :Off-WhiteMasse moléculaire :327.44Prifinium Bromide
CAS :Produit contrôléStability Light Sensitive
Applications Prifinium Bromide is a synthetic antispasmodic drug; parasympatholytic. Prifinium Bromide is used as a quartenary anticholinergic agent.
References Kumada, S. et al.: Arzneim.-Forsch., 20, 237 (1970); Nakai, T. et al.: Arzneim.-Forsch., 20, 1112 (1970); Bettini, V. et al.: Farm. Ed. Prat., 33, 392 (1978);Formule :C22H28N·BrCouleur et forme :NeatMasse moléculaire :386.37Triazophos 85%
CAS :Produit contrôléApplications An organophosphorus insecticide.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bhosale, B., et al.: Pestol., 33, 38 (2009), Dash, D., et al.: J. Entomol. Res., 33, 105 (2009), Hu, Y., et al.: J. Agric. Food Chem., 58, 2801 (2010),Formule :C12H16N3O3PSDegré de pureté :85%Couleur et forme :Light YellowMasse moléculaire :313.314-Aminohippuric-d4 Acid
CAS :Produit contrôléApplications Labelled 4-Aminohippuric Acid is used in the measurement of renal plasma flow as a diagnostic tool which may be applied towards kidney disorders.
References Phillips, R. et al.: Am. J. Physiol., 152, 523 (1948);Formule :C92H4H6N2O3Couleur et forme :NeatMasse moléculaire :198.21Ramosetron Hydrochloride
CAS :Produit contrôléStability Hygroscopic
Applications Selective serotonin 5HT3, receptor antagonist; structurally different from Ondansetron (O655000), Granisetron (G780000). Antiemetic.
References Miyata, K., et al.: J. Pharmacol. Exp. Ther., 259, 15 (1991), Miura, H., et al.: Biomed. Chromatogr., 8, 103 (1994), Tabata, H., et al.: Arzneim.-Forsch., 45, 760 (1995),Formule :C17H17N3O·ClHCouleur et forme :NeatMasse moléculaire :315.8Propyl dihydrojasmonate (Mixture of Diastereomers)
CAS :Produit contrôléFormule :C15H26O3Couleur et forme :Off-WhiteMasse moléculaire :254.37(-)-Biotin Sulfoxide
CAS :Applications (-)-Biotin Sulfoxide, is a metabolite of Biotin (B389040), which is a growth factor present in minute amounts in every living cell, and plays an indispensable role in numerous naturally occurring carboxylation reactions.
References du Vigneaud, et al.: J. Biol. Chem., 146, 475 (1942), Traub, et al.: Nature, 178, 649 (1956), Siegel, H., et al.: Experienta, 37, 789 (1981), Vesely, D.L., Science, 216, 1329 (1982), Hugues, M., et al.: Biochemistry, 31, 12 (1992),Formule :C10H16N2O4SCouleur et forme :White To Off-WhiteMasse moléculaire :260.31Normaprotiline Hydrochloride
CAS :Produit contrôléFormule :C19H21NCouleur et forme :NeatMasse moléculaire :263.38Tetrasul
CAS :Produit contrôléApplications Tetrasul is a chlorinated diphenyl sulfide aracacide. Tetrasul is used for the control of mites and other pests in food and gardening crops.
References Hansen, T. et al.: Tids. Plant., 74, 618 (6970); Dittrich, V.: Zeitsch. Angew. Entomol., 61, 240 (1968);Formule :C12H6Cl4SCouleur et forme :NeatMasse moléculaire :324.05Adenosine 5'-Monophosphate
CAS :Produit contrôléApplications Adenosine 5'-Monophosphate is a natural occurring nucleotide and a useful ligand determinant that facilitate the binding of APS reductase inhibitors and activates adenosine receptor agonists.
References Hong, J.A. et al.: J. Med. Chem., 52, 5485 (2009); Korboukh I. et al.: J. Med. Chem., 55, 6467 (2012)Formule :C10H14N5O7PCouleur et forme :NeatMasse moléculaire :347.22Formetanate Hydrochloride
CAS :Applications Formetanate is an insecticide and acaricide.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ong, K., et al.: Food Chem., 55, 153 (1996); Hislop, R., et al.: Protection Ecol., 3, 157 (1981)Formule :C11H15N3O2·ClHCouleur et forme :White To Light YellowMasse moléculaire :257.727α-Hydroxy-4-cholesten-3-one-d7
CAS :Produit contrôléApplications Labelled 7α-Hydroxy-4-cholesten-3-one (H825130). 7α-Hydroxy-4-cholesten-3-one is a metabolite of Cholesterol (C432501).
References Connor, W., et al.: J, Clin. Invest., 48, 1363 (1969),Formule :C27H37D7O2Couleur et forme :White To Off-WhiteMasse moléculaire :407.68N-Isopropyl Noratropine
CAS :Produit contrôléImpurity Ipratropium EP Impurity E
Applications N-Isopropyl Noratropine is a Noratropine derivative, an intermediate in the production of Ipratropium.
References Simms, P., et al.: J. Pharm. Biomed. Anal., 17, 841 (1998),Formule :C19H27NO3Couleur et forme :NeatMasse moléculaire :317.425-Hydroxy Albuterol Hemisulfate Salt
CAS :Produit contrôléApplications The 5-hydroxy analogue of the bronchodilator, Albuterol (A514500).
Formule :C13H21NO4H2SO4Couleur et forme :NeatMasse moléculaire :304.35Anilofos
CAS :Produit contrôléApplications Anilofos is an herbicide that is practically insoluble in water.
Formule :C13H19ClNO3PS2Couleur et forme :NeatMasse moléculaire :367.85Leptophos
CAS :Produit contrôléStability Moisture Sensitive
Applications Leptophos is an organophosphorus pesticides which exhibits a stronger endocrine disruption than its (+)form in JEG-3 cell.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lu, Y., et al.: Zhejiang Gongye Daxue Xuebao, 40, 152-156 (2012)Formule :C13H10BrCl2O2PSCouleur et forme :Off-WhiteMasse moléculaire :412.07Clothianidin-d3, 13C1
CAS :Produit contrôléApplications Clothianidin-d3, 13C1 is the isotope labelled analog of Clothianidin. Clothianidin is a neonicotinoid insecticide for use in food crops.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kamel, A., et al.: J. Agric. Food Chem., 58, 5926 (2010), Lynd, L., et al.: Energy Environ. Sci., 3, 1150 (2010), Cresswell, J., et al.: Ecotoxicology, 20, 149 (2011),Formule :C5CH5D3ClN5O2SCouleur et forme :NeatMasse moléculaire :253.692-Isoniazid
CAS :Produit contrôléApplications An impurity of Isoniazid (I821450), which is an antibiotic for treatment of Mycobacterium tuberculosis and inhibits mycolic acid biosynthesis. Intermediate used for the synthesis of analogs of antitumor agent 1-acetyl-2-picolinoylhydrazine.
References Brewer, G.A., et al.: Anal. Profiles. Drug. Subs., 6, 183 (1977), Weber, W.W., et al.: Clin. Pharmacokinet., 4, 401 (1979); Rutner, H., et al.: Cancer. Chem. Rep., 58, 803 (1974)Formule :C6H7N3OCouleur et forme :WhiteMasse moléculaire :137.14Testosterone Sulfate Triethylamine Salt
CAS :Produit contrôléApplications A metabolite of Testosterone (T155000). It is a urinary metabolite of Androstenedione (A637550) in patients with Addison's disease and also used as a marker in blood plasma for detection of prostate cancer.
References Lokhov, P.G. et al.: Metabolomics, 6, 156 (2010); Bonnaire, Y. et al.: J. Anal. Toxicol., 19, 175 (1995); Tamm, J. et al.: Steroids, 8, 659 (1966);Formule :C25H43NO5SCouleur et forme :NeatMasse moléculaire :469.68N-Acetyl Glyphosate-d3
CAS :Produit contrôléApplications A labelled metabolite of the pesticide Glyphosphate (G765000).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Siehl, D.L. et al.: J. Biol. Chem., 282, 11446 (2007); Env. Prot. Agen. EPA: Fed. Reg., 74, 67129 (2009);Formule :C5H7D3NO6PCouleur et forme :White To Off-WhiteMasse moléculaire :214.13N1,N12-Diacetylspermine Dihydrochloride
CAS :Stability Hygrscopic
Applications N1,N12-Diacetylspermine Dihydrochloride is a diacetylated derivative of Spermine (S680510) and is recognized as a novel tumor marker in patients with breast and colorectal cancers.
References Kato, M., et al.: Anticancer Res., 34, 3053 (2014); Umemori, Y., et al.: Clin. Chim. Acta, 411, 1894 (2010); Kawakita, M., et al.: J. Biochem., 139, 315 (2006); Hiramatsu, K., et al.: Clin. Cancer Res., 11, 2986 (2005)Formule :C14H32Cl2N4O2Couleur et forme :NeatMasse moléculaire :359.34Clofibric-D4 Acid
CAS :Produit contrôléApplications Antilipemic.
References Chang, et al.: Biochem. Pharmacol., 16, 2053 (1967), Walsh, et al.: Arch. Biochem. Biophys., 130, 7 (1969), Witiak, et al.: J. Med. Chem., 14, 754 (1971),Formule :C102H4H7ClO3Couleur et forme :NeatMasse moléculaire :218.67Hydroxy Bosentan
CAS :Produit contrôléFormule :C27H29N5O7SCouleur et forme :NeatMasse moléculaire :567.61Eltrombopag-13C4
CAS :Produit contrôléFormule :C2113C4H22N4O4Couleur et forme :Light Yellow To Dark OrangeMasse moléculaire :446.44Imidacloprid-urea
CAS :Applications Imidacloprid-urea is a metabolite of Imidacloprid (I275990), a neonicotinoid; the active ingredient in certain neuro-active insecticides. Used in pest control.
References Chauzat, M., et al.: Env. Entomol., 38, 514 (2009), Patial, A., et al.: Env. Ecol., 27, 320 (2009), Fernandez-Bayo, J., et al.: J. Agric., Food Chem., 57, 5435 (2009); Aregahegn, K. et al.: Env. Sci. Tech., 51, 2660 (2017);Formule :C9H10ClN3OCouleur et forme :Off-WhiteMasse moléculaire :211.65Bromfenac Sodium Sesquihydrate
CAS :Produit contrôléApplications Bromfenac is a non-steroidal anti-inflammatory agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Obach, R., et al.: Drug Metab. Disposition, 36, 1385 (2008), MacDonald, J., et al.: Toxicol. Sci., 110, 40 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),Formule :C15H11BrNO3·2Na·3H2OCouleur et forme :Light YellowMasse moléculaire :766.34Testosterone β-D-Glucuronide Monosodium Salt
CAS :Produit contrôléStability Hygroscopic
Applications Metabolite of Testosterone (T155000).
References Shibata, N., et al.: Biochem. J., 368, 783 (2002), Sonneveld, E., et al.: Toxicol. Sci., 83, 136 (2005), Schulze, J., et al.: J. Clin. Endocrinol. Metab., 93, 2500 (2008), Sten, T., et al.: Drug Metab. Disposition, 37, 417 (2009),Formule :C25H35O8·NaCouleur et forme :White To Off-WhiteMasse moléculaire :486.53trans-α-Asarone
CAS :Produit contrôléFormule :C12H16O3Couleur et forme :White To Off-WhiteMasse moléculaire :208.25Petromyzonol 24-Sulfate Sodium Salt
CAS :Produit contrôléFormule :C24H41O7S·NaCouleur et forme :NeatMasse moléculaire :496.63Malathion
CAS :Applications Malathion is a pestanal and used primarily as an insecticide. Malathion is also useful in cannabis testing kits as a component of pesticide mixes (P698230).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Josse, R et al.: Chem. Bio., Interact., 209, 76 (2014);Formule :C10H19O6PS2Couleur et forme :Colourless To Light YellowMasse moléculaire :330.36Fludioxonil
CAS :Applications Fludioxonil is a nonsystemic phenylpyrrole fungicide structurally related to pyrrolnitrin. Also useful in cannabis testing kits as a component of pesticide mixes (P698235).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Chang, C.-H., et al.: Biochemistry 30, 5352 (1991),Formule :C12H6F2N2O2Couleur et forme :NeatMasse moléculaire :248.18Desacetyl Diltiazem
CAS :Impurity Diltiazem EP Impurity F
Applications Desacetyl Diltiazem (Diltiazem EP Impurity F) is a metabolite of Diltiazem (D460620).
References Shallcross, H., et al.: Br. Med. J., 295, 1236 (1987), Yeung, P.K.F., et al.: Drug Metab. Dispos., 18, 1055 (1990), Cashman, J.R., et al.: J. Med. Chem., 34,2049 (1991),Formule :C20H24N2O3SCouleur et forme :White To BrownMasse moléculaire :372.48Indole-3-acetyl β-D-Glucopyranose
CAS :Applications A metabolite of Indole-3-acetic acid in plants.
References Barratt, N., et al.: Physiol. Plant, 105, 207 (1999), Jackson, R., et al.: J. Biol. Chem., 276, 4350 (2001), Staswick, P., et al.: Plant Cell, 17, 616 (2005),Formule :C16H19NO7Couleur et forme :NeatMasse moléculaire :337.32(6α,9β,11β,16α)-9,11-Epoxy-6-fluoro-21-hydroxy-16,17-[(1-methylethylidene)bis (oxy)]pregna-1,4-diene-3,20-dione
CAS :Impurity Fluocinolone Acetonide EP Impurity E
Stability Hygroscopic
Applications (6α,9β,11β,16α)-9,11-Epoxy-6-fluoro-21-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione, can be used in the production of fluocinolone acetonide (F455800).
References Grinenko, G.S, Khimiko-Farmatsevticheskii Zhurnal, 12, 110 (1978), Sammul, et al.: J. Assoc. Off. Agric. Chem., 47, 952 (1964), Emerson, M.V., et al.: BioDrugs, 21, 245 (2007),Formule :C24H29FO6Couleur et forme :NeatMasse moléculaire :432.48Allo-3α-tetrahydro Cortisol
CAS :Produit contrôléStability Hygroscopic
Applications A metabolite of Cortisol (H714615).
References Quinkler, M., et al.: J. Clin. Endocrinol. Metab., 88, 2384 (2003), Draper, N., et al.: J. Endocrinol., 186, 251 (2005), Kotlowska, A., et al.: Clin. Biochem., 42, 448 (2009),Formule :C21H34O5Couleur et forme :Off White SolidMasse moléculaire :366.49Diquat Dibromide Monohydrate
CAS :Produit contrôléApplications Contact herbicide used also to produce desiccation and defoliation.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Brian, et al.: Nature, 181, 446 (1958), Gaines, T.B., et al.: Fundam. Appl. Toxicol., 7, 299 (1986),Formule :C12H12N2·2Br·H2OCouleur et forme :Light Yellow To BrownMasse moléculaire :362.06Coumoxystrobin
CAS :Produit contrôléApplications Coumoxystrobin is a Coumarin (C755380) based fungicide.
References Guan, A., et al.: Pest Manag. Sci., 67, 647 (2011);Formule :C26H28O6Couleur et forme :NeatMasse moléculaire :436.5Sorbic Acid-13C2
CAS :Produit contrôléApplications Sorbic Acid-13C2 is an isotope labelled compound of Sorbic Acid (S676890). Sorbic Acid is a naturally occurring organic compound first isolated from unripe berries. Sorbic acid has been used as a food preservative and as an inhibitor of Clostridium Botulinum bacteria in meat products in order to reduce the amount of nitrites which produce carcinogenic nitroamines.
References Van, M.C., et al.: Int. J. Food. Microbiol., 160, 124 (2012); Li, J., et al.: J. Am. Soc. Mass. Spec., 23, 1625 (2012);Formule :C413C2H8O2Couleur et forme :NeatMasse moléculaire :114.11Captan-d6
CAS :Produit contrôléStability Toxic
Applications Isotopopically Labelled analogue of Captan (C175725), which is an acetylcholinesterase inhibitor acting as a fungicide (1), often added to pesticide mixtures to control diseases among fruits and vegetables. Detected through various analytical techniques involving pesticide residues such as MS-PD and GC-MS (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants. Also used in cannabis testing.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Afful, S. et al.: Res. J. App. Sci. Eng. Tech. (2010) 14 Jul:2(6) 592-52. Engelen, K. et al.: J. Proteome. Res. 2010 Oct 1;9(10):4919-263. Lagunas-Allue, L. et al.: Anal. Bioanal. Chem. 2010 Oct;398(3):1509-23Formule :C92H6H2Cl3NO2SCouleur et forme :White To Light YellowMasse moléculaire :306.637α-Thiomethyl Spironolactone-d7 (Major)
CAS :Produit contrôléApplications A labelled metabolite of Spironolactone.
References Gochman, N., et al.: J. Pharmacol. Exp. Ther., 135, 312 (1962), Tori, K., et al.: Steroids, 4, 713 (1964), Solymoss, B., et al.: Toxicol. Appli. Pharmacol., 18, 586 (1971),Formule :C23H25D7O3SCouleur et forme :NeatMasse moléculaire :395.616-Hydroxy Bentazon-d7
CAS :Produit contrôléApplications A labelled metabolite of Bentazon, a selective post-emergence herbicide.
References Klibanov, A., et al.: Science, 221, 259 (1983), Huber, R., et al.: Rev. Environ. Contam. Toxicol., 137, 111 (1994), Roper, J., et al.: Wat. Res., 29, 2720 (1995),Formule :C10H5D7N2O4SCouleur et forme :NeatMasse moléculaire :263.32Picaridin-d3
CAS :Produit contrôléApplications Acts on certain olfactory receptor cell types to reduce the activating or attracting effect of odor sources.Insect repellent.
References Boeckh, J., et al.: Pestic. Sci., 48, 359 (1996), Yap, H.H., et al.: J. Vector Ecol., 23, 62 (1998),Formule :C12H20D3NO3Couleur et forme :ColourlessMasse moléculaire :232.33Clodinafop Propargyl
CAS :Applications Herbicides for weed control in wheat.
References Aliverdi, A., et al.: Weed Biol. Management, 9, 292 (2009), Hochberg, O., et al.: Weed Res., 49, 37 (2009), Liu, B., et al.: J. Agric. Food Chem., 58, 2673 (2010),Formule :C17H13ClFNO4Couleur et forme :NeatMasse moléculaire :349.749α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one
CAS :Impurity Clobetasol Propionate EP Impurity J
Applications 9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one (Clobetasol Propionate EP Impurity J) is an impurity in the synthesis of Clobetasol 17-Propionate (C583500), a topical corticosteroid. Glucocorticoid; anti-inflammatory.
References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),Formule :C25H30ClFO4Couleur et forme :NeatMasse moléculaire :448.95Netobimin Sodium Salt
CAS :Applications Phenylguanidine anthelmintic. Anthelmintic.
References Williams, J.C., et al.: Am. J. Vet. Res., 46, 2188 (1985), Delatour, P., et al.: J. Vet. Pharmacol. Ther., 9, 230 (1986),Formule :C14H19N4O7S2·NaCouleur et forme :Yellow-OrangeMasse moléculaire :442.44Diazoxide-d3
CAS :Produit contrôléApplications Diazoxide-d3 is the labeled analogue of Diazoxide (D417305), which reduces status epilepticus neuron damage in diabetes.
References Baba, A., et al.: J. Neurosci., 23, 7737 (2003); Bancila, V., et al.: J. Neurochem., 90, 1243 (2004); Bancila, V., et al.: J. Biol. Chem., 280, 8793 (2005)Formule :C8H4D3ClN2O2SCouleur et forme :NeatMasse moléculaire :233.69Terbufos-sulfoxide
CAS :Produit contrôléApplications Terbufos-sulfoxide was identified in vegetables and fruit by gas chromotography.
References Zhang, Q., et al.: Shandong Huagong, 45, 57 (2016)Formule :C9H21O3PS3Couleur et forme :NeatMasse moléculaire :304.43Imipenem, Monohydrate
CAS :Produit contrôléFormule :C12H17N3O4S·H2OCouleur et forme :White To Light YellowMasse moléculaire :317.36Chlorimuron-ethyl-d5
CAS :Produit contrôléApplications Chlorimuron-ethyl-d5 is a labeled analogue of Chlorimuron-ethyl (C371273), which is used in weed control method as herbicide.
References Sada, Y., et al.: PCT Int. Appl. 45 pp. (2020)Formule :C15H10D5ClN4O6SCouleur et forme :NeatMasse moléculaire :419.852-(1-Hydroxyethyl) Promazine
CAS :Applications A metabolite of Acepromazine (A130900).
References Cossum, P., et al.: Drug Dispos., 9, 321 (1988), Stowell, L., et al.: J. Anal. Toxicol., 22, 166 (1998),Formule :C19H24N2OSCouleur et forme :NeatMasse moléculaire :328.47Fipexide Hydrochloride
CAS :Produit contrôléApplications Fipexide Hydrochloride is one of five potential drug candidates to overcome the melphalan-induced vascular toxicity.
References Yang, Y., et al.: Tumour Biol., 37, 6709-6718 (2016);Formule :C20H21ClN2O4•(HCl)Couleur et forme :NeatMasse moléculaire :388.843646Zolmitriptan-d6 (Major)
CAS :Produit contrôléStability Hygroscopic
Applications A Serotonin 5HTID-receptor agonist.
References Glen, R.C., et al.: J. Med. Chem., 38, 3566 (1995), Seaber, E., et al.: Brit. J. Clin. Pharmacol., 41, 141 (1996), Tepper, S.J., et al.: Curr. Med. Res. Opin., 15, 254 (1999)Formule :C16H15D6N3O2Couleur et forme :NeatMasse moléculaire :293.39CRL-40,941
CAS :Produit contrôléApplications CRL-40,941 is a wakefulness-promoting agent. It was found to produce antiaggressive effects in animals.
References Lafon, L.: US4489095 (A) (1984)Formule :C15H13F2NO3SCouleur et forme :WhiteMasse moléculaire :325.33Sumatriptan Succinate
CAS :Produit contrôléApplications Sumatriptan Succinate is a selective 5-HT1B/1D-receptor agonist with anticonvulsant properties (1,2). Sumatriptan Succinate is used for migraine relief (2).
References (1) Razzaque, Z., et al.: Br J Clin Pharmacol. 47, 75 (1999) (2) Cady, R. K., et al.: J Headache Pain. 18, 17 (2017)Formule :C14H21N3O2S·C4H6O4Couleur et forme :White To Off-WhiteMasse moléculaire :413.494-Hydroxy Estrone 1-N7-Guanine
CAS :Produit contrôléStability Hygroscopic
Applications 4-Hydroxy Estrone 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.
References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),Formule :C23H25N5O4Couleur et forme :NeatMasse moléculaire :435.48Methyl Arsonic Acid Disodium Salt (~40%, Contain Sodium Sulfate)
CAS :Stability Hygroscopic
Applications Methylarsonic acid is used as herbicide.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gaines, T.B., et al.: Fundam. Appl. Toxicol., 7, 299 (1986), Cao, X., et al.: Food Chem., 113, 720 (2009), Jedynak, L., et al.: Sci. Total Environ., 407, 945 (2009),Formule :CH3AsO3·2NaCouleur et forme :White To Off-WhiteMasse moléculaire :183.93Tranexamic Acid Dimer
CAS :Produit contrôléImpurity Tranexamic EP Impurity A
Applications Tranexamic Acid Dimer (Tranexamic EP Impurity A) is a Tranexamic Acid (T714505) impurity.Formule :C16H27NO4Couleur et forme :White To Off-WhiteMasse moléculaire :297.39Difethialone
CAS :Produit contrôléApplications Difethialone is an anticoagulant rodenticide widely used to control rodent infestations.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Eason, C., et al.: Ecotoxicology, 11, 35 (2002), Hegdal, P., et al.: Environ. Toxicol. Chem., 7, 245 (1988), Stone, W., et al.: Environ. Contam. Tox., 70, 34 (2003),Formule :C31H23BrO2SCouleur et forme :Off-WhiteMasse moléculaire :539.48Nilotinib Monohydrochloride Monohydrate
CAS :Produit contrôléFormule :C28H22F3N7O·ClH·H2OCouleur et forme :NeatMasse moléculaire :583.99Farnesol (Mixture of Isomers)
CAS :Produit contrôléApplications Farnesol is an acyclic sesquiterpene alcohol which is used in perfumery due to its sweet and floral scent. Flavoring agent. Antibacterial.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kromidas, L. et al.: Int. J. Cosmet. Sci., 28, 103 (2006); Joo J. et al.: Canc. Lett., 287, 123 (2009);Formule :C15H26OCouleur et forme :NeatMasse moléculaire :222.37
