Toxicologie

Applications 7,13-Bisside chainpacltaxel is a derivative of Paclitaxel (P132500) which has anticancer properties.
References Zhong, T., et al.: Bioconjugate Chem., 29, 437-444 (2018)

Impurity Atorvastatin EP Impurity D
Applications O-Methyl Atovaquone (Atorvastatin EP Impurity D) is a Atovaquone derivative that shows protozoacidal activity against Plasmodium falciparum.
References Danoun, S., et. al.: Heterocycl. Commun., 5, 343 (1999)

Stability Hygroscopic
Applications 3-Iodothyronacetic Acid is a 3-Iodothyronamine metabolite that has functional effects in FRTL-5 thyroid cells.
References Agretti, P. et al.: J. Mol. Endocrinol., 47, 23 (2011);

Applications 2-Methylphenyl Diethylcarbamate is an intermediate in the synthesis of o-Cresol (C781910), which is a compound used as a disinfectant and have also been used as antiseptic in surgery.
References Razavi, S.M., et al.: Nat. Prod. Res., 26, 2148 (2012); Asadollahi-B. M., et al.: Environ. Toxicol. Pharmacol., 34, 826 (2012);

Applications (S)-Efaveirenz N-β-Glucoronide-Methyl Ester is an intermediate in the synthesis of (S)-Efavirenz N-β-D-Glucuronide, the N-glucuronide derivative of (S)-Efavirenz (E425000); a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral.
References Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995)

Applications Used for the preparation of heterocyclic sulfonamide compounds as Edg-1 antagonists useful in the treatment of cancer.

Applications An intermediate in the preparation of HIV-integrase inhibitors
References Summa, V., et al.: J. Med. Chem., 51, 5843 (2008),