Produits biochimiques et réactifs

<p>Somatostatin 1-28 is a synthetic peptide that is derived from the natural hormone somatostatin, which is primarily sourced from neuroendocrine cells in the hypothalamus, pancreas, and gastrointestinal tract. This peptide functions as a potent inhibitor of several physiological processes through its interaction with specific G-protein-coupled somatostatin receptors. These receptors are widely distributed across various tissues and organs, allowing somatostatin to modulate the release of several hormones and neurotransmitters.</p>

<p>H-Gln-2-ClTrt-Resin is a resin that consists of polystyrene crosslinked with divinylbenzene. It is used in peptide synthesis to provide amino acids and building blocks for the synthesis of peptides and proteins. This resin can be used as a component in the production of amines, alcohols, thiols, and other organic compounds. The crosslinking agent in this resin is divinylbenzene (DVB).</p>

<p>Anti Na Channel ll (467-485) (Rat) Serum is an anti-Na channel antibody that can be used for research purposes. It is a monoclonal antibody that has been generated according to the sequence and features of the rat N-type voltage-gated sodium channels. The affinity of this antibody for its target is high, with a Kd of 0.5 nM. This antibody can be used in immunoassays, Western blots and immunoprecipitations to determine the level of Na channel expression in various tissues.</p>

<p>AM-1638 is a fatty acid that has been shown to increase the production of insulin in pancreatic cells in vitro. It has also been shown to have long-term safety in mouse models and was well tolerated when orally administered to wild-type mice. AM-1638 is an alkanoic acid with high lipophilicity and low molecular weight that can be used as a molecule for the treatment of type 2 diabetes.</p>

<p>2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine is a phospholipid compound with a wide range of characteristics and applications. It has been found to have various effects on the body, including interactions with capsicum, electrolytes, and dopamine receptors. Additionally, it has shown potential in research related to Gaucher disease, chemokine signaling, glucosylceramide metabolism, and cancer studies.</p>

<p>SX-682 is an orally bioavailable antagonist of the chemokine receptor CCR1, which is derived from advanced medicinal chemistry efforts targeting inflammatory pathways. Its mode of action involves selectively blocking the interaction between CCR1 and its ligands, thereby inhibiting the recruitment and activation of immune cells such as monocytes and macrophages. This action modulates inflammatory responses and has shown promise in dampening pathological inflammation.</p>

<p>Antithrombin III heavy tryptic peptide standard for protein identification and quantitation studies. Antithrombin III is a glycoprotein found in blood plasma and is involved in the regulation of the coagulation process.</p>

<p>GLP-2 (Mouse)-EIA Kit is a kit for the quantitative measurement of GLP-2 in mouse serum. It consists of a standard, antibody and reagents to measure GLP-2 in mouse serum. The assay has been validated for use with sera from mice. For research use only. Not for diagnostic or therapeutic purposes.</p>

<p>E 52862 (S1RA) is a monoclonal antibody that targets the α2δ subunit of voltage-gated calcium channels. It blocks the binding of ATP and reduces neuronal excitability, providing antinociception without causing dependence or addiction. E 52862 has been shown to be an effective treatment for diabetic neuropathy in vivo models. The drug has also been shown to have a sub-effective dose, which may reduce its side effects. E 52862's receptor activity may be due to its ability to inhibit glutamate release and cyclin D2 expression, which are both involved in pain transmission.</p>

<p>Monobiotin INSL4 is a biologically active peptide that belongs to the group of relaxins. It is an analogue of human relaxin and has been labelled with biotin for use in in vitro experiments.</p>

<p>16:0-18:1 Diether Peptide is a research tool that can be used to study protein interactions and receptor ligand relationships. It also inhibits ion channels, which are responsible for regulating the flow of ions across the cell membrane. 16:0-18:1 Diether Peptide has been shown to activate antibodies and is a high purity, chemically synthesized molecule with CAS No. 141456-20-4.</p>

<p>Spinosad is a stereoselective and anomeric insecticide. It is derived from the natural product (1S,2R,5S,7R,9R,10S,14R,15S,19S)-19-ethyl-15-hydroxy-14-methyl-7-[(2R,3R,4R,5S,6S)-3,4,5-trimethoxy-6-methyloxan-2yl]oxy-20-oxatetracyclo[10.10.0.02,10.05 9]docosa 3 11 diene 13 21 dione (spinosyn). The spinosyns are synthesized by the oxidative deamination of the axial lactone with hydroxylamine or azide followed by an intramolecular cyclization to form the 14 alpha-, 15 beta-, 16 alpha-, 17 beta-, 18 beta-, 19 alpha-, 20 beta</p>

<p>Pep2-EVKI is a potent and selective inhibitor of protein synthesis. It binds to the β-adrenergic receptors, metabotropic glutamate receptor, and tyrosine phosphatases, inhibiting their activity. Pep2-EVKI has been shown to alleviate depression in mice without affecting locomotor activity or food intake. This drug also inhibits the synthesis of messenger RNA (mRNA) in rat brain tissue. The drug interacts with wild-type mice but not with those that lack the m1 receptor gene. Pep2-EVKI has shown antidepressant effects in wild-type mice, but not in those lacking the m1 receptor gene.</p>

<p>5-(6-(4-(Trifluoromethyl)-4-(4-(trifluoromethyl)phenyl)piperidin-1-yl)pyridazin-3-yl)-1,3,4-oxadiazol-2-yl)methanol is a drug that inhibits the lipid biosynthesis of viruses by inhibiting the activity of a number of enzymes. This drug has been shown to be active against HIV type 1 and 2, influenza A virus, hepatitis C virus, and herpes simplex virus. It has also been shown to have anticancer properties in vitro and in vivo. 5-(6-(4-(Trifluoromethyl)-4-(4-(trifluoromethyl)phenyl)piperidin-1-yl)pyridazin-3-yl)-1,3,4-oxadiazol-2-yl)methanol is</p>

<p>GSK343 is a small-molecule inhibitor, which is synthetically derived with the specific purpose of targeting and inhibiting the activity of the enzyme EZH2, a key component of the Polycomb Repressive Complex 2 (PRC2). This enzyme is responsible for the tri-methylation of histone H3 on lysine 27 (H3K27me3), a modification that plays a crucial role in gene silencing and epigenetic regulation.</p>

<p>Cicloprolol-d5 is a protein inhibitor that belongs to the class of medicinal compounds known as cyclin-dependent kinase inhibitors. It works by blocking the activity of kinases, which are enzymes involved in cell cycle regulation and proliferation. Cicloprolol-d5 has been shown to induce apoptosis, or programmed cell death, in cancer cells. This compound has demonstrated anticancer activity in Chinese hamster ovary cells and human tumor cell lines. It is a potent inhibitor of cyclin-dependent kinases and may have potential as an anticancer agent.</p>

<p>Pgl-135 hydrochloride monohydrate is a research tool that is used in the study of cell biology, pharmacology and ion channels. It is an inhibitor of ligand-gated ion channels, which are found in the central nervous system and play a role in the regulation of neurotransmitter release. Pgl-135 hydrochloride monohydrate has been shown to activate GABAA receptors by binding to them as a ligand, and inhibit voltage-gated calcium channels. It has also been shown to have immunosuppressive properties when used as an adjuvant or antigen carrier. Pgl-135 hydrochloride monohydrate has also been used in studies on protein interactions and antibody production.</p>

<p>FIPI is a protein that is involved in the regulation of cell lysis. It binds to fatty acids and then causes cytosolic calcium levels to increase, leading to cell lysis. FIPI has been shown to be involved in the regulation of epidermal growth factor (EGF) synthesis and signal pathways involving EGF receptors. The role of FIPI in infectious diseases such as HIV infection or malaria is unknown. Studies have found that FIPI can inhibit signal transduction by binding to the receptor for EGF, which may lead to new drugs for the treatment of cancer or viral infections.</p>

<p>Halogenated derivative of febrifugine; coccidiostat</p>

<p>SC-26196 is a potential new anti-cancer drug that inhibits the activation of fatty acid receptors. SC-26196 blocks receptor activity, which reduces the growth of cancer cells in cell culture. This drug also has inhibitory properties on tumor growth in xenograft mice, and may be useful for the treatment of cardiac dysfunction or other diseases related to fatty acid metabolism. SC-26196 is a complex molecule with high potential for drug interactions. It is a polyunsaturated molecule that can be activated by radiation and has been shown to have cardioprotective effects in rats with myocardial infarction.</p>

<p>LDV FITC is a monoclonal antibody that binds to the extracellular domain of the human CD4 molecule. It is expressed as a heterodimer and has been shown to inhibit kinase signaling pathways in human lymphocytes. LDV FITC is used in cell-binding assays to detect the presence of CD4 molecules on cells and can be used to screen for HIV-1 antibodies. LDV FITC has also been shown to be effective against ischemia/reperfusion injury in rat hearts.</p>

<p>TC 2559 Fumarate is a small molecule that modulates ion channels. It is an activator of the TRPV1 receptor and a ligand for the GPR107 receptor, which are both members of the transient receptor potential (TRP) family. TC 2559 Fumarate inhibits voltage-gated potassium channels and may also inhibit L-type calcium channels. TC 2559 Fumarate has been shown to have anti-inflammatory effects in vitro, as well as in vivo by inhibiting the production of inflammatory cytokines such as IL-2, IL-6, IL-12, IFN-γ, TNFα, and chemokines such as KC, MIP1α, MIP1β. TC 2559 Fumarate can be used to study protein interactions and as a research tool in cell biology or pharmacology.<br>TC 2559 Fumarate is not expected to cause any adverse effects to humans at doses up to 100mg/kg</p>

<p>Pf-05236216 hydrochloride is a potent and selective inhibitor of the transient receptor potential vanilloid type 1 (TRPV1) ion channel. Pf-05236216 hydrochloride has been shown to inhibit TRPV1 activation by capsaicin, resiniferatoxin, and heat in vitro and in vivo. Pf-05236216 hydrochloride also inhibits acid-sensing ion channels (ASICs) at concentrations below those required for TRPV1 inhibition. Pf-05236216 hydrochloride has been used as a research tool to study the function of TRPV1 and ASICs, as well as in studies of cell biology and peptides.</p>

<p>Insulin I is a mouse insulin. Insulin I is an ion channel activator, which means that it can open and close ion channels in the cell membrane to regulate the flow of ions into and out of cells. Insulin I is a receptor ligand, which means that it binds to a receptor on the surface of cells to activate or inhibit their function. Insulin I is used as a research tool for pharmacology and cell biology, as well as for the study of protein interactions. It has been shown to have high purity. Insulin I has also been shown to be an inhibitor of cellular growth, but not always an apoptosis inducer.</p>

<p>The ALB, GIG20, GIG42 MS Calibrator (25nmol) is a Proteomics Tools product that has been designed to support the identification of biologically active peptides in proteomics. The ALB, GIG20, GIG42 MS Calibrator (25nmol) is a tryptic peptide derived from human serum albumin and can be used as a precursor for the identification of other tryptic peptides in proteomic samples. The New England Peptide Company offers this product at a competitive price and with high quality.</p>

<p>CM 1 is a synthetic derivative of the natural compound apigenin. It inhibits the activity of matrix metalloproteinase-9 (MMP-9) and has been shown to suppress allergic symptoms in animal models. CM 1 has also been shown to be effective against some types of skin cancer, such as squamous carcinoma, when applied topically. CM 1 induces autophagy in vivo and has been shown to have biological properties that are similar to those of apigenin. This compound also promotes autophagy in cultured human cells by inhibiting mitochondrial membrane potential and increasing levels of reactive oxygen species (ROS).</p>

<p>Zymostenol-d7 is a compound that is used in the synthesis of tamoxifen. It is also a multidrug resistance (MDR) inhibitor and is used as a cancer drug. Zymostenol-d7 inhibits the enzyme catalytic mechanism, which is required for cell division. This inhibition prevents the cell from dividing and growing uncontrollably, thereby preventing cancer growth. Zymostenol-d7 has been shown to exhibit anticancer activity by inhibiting the growth of tumor cells in vitro and in vivo.</p>

<p>Inhibitor of COX-2 enzyme; anti-inflammatory; analgesic</p>

<p>SF-11 is a fatty acid that has been shown to have antidepressant-like activity. It binds to fatty acid receptors in the brain and stimulates the production of prostaglandins, which are involved in the regulation of mood. SF-11 also has a metal chelator effect, which may be due to its ability to form complexes with metals such as copper and iron. This may prevent oxidation reactions and lead to an increase in mitochondrial membrane stability. SF-11 is a molecule that has been studied for its potential use as a monoclonal antibody coating or radiation shield. The high cytotoxicity of SF-11 against certain cell lines has been attributed to its significant ability to penetrate cells and allow molecules such as c-reactive protein (CRP) and germination rate into cells. The functional theory may explain this phenomenon, suggesting that it is possible for SF-11 to bind with CRP or germination rate and protect them from degradation by proteases or other factors within the cell</p>

<p>The S-100ß ELISA kit is a solid phase sandwich enzyme-linked immunosorbent assay (ELISA) that detects the presence of S-100ß protein in serum, plasma, or cerebrospinal fluid. The assay employs an antibody specific for S-100ß protein and an enzyme-labeled anti-IgG antibody as a second antibody to detect bound S-100ß protein.</p>

<p>JH-VIII-157-02 is an analog of alectinib, a drug that binds to the kinase domain of tyrosine kinases, inhibiting their activity. The tyrosine kinases are involved in many cellular processes such as cell growth and differentiation. JH-VIII-157-02 has shown activity against non-small cell lung cancer cells and has been studied in clinical trials for its efficacy against this disease. It is believed that the drug blocks constitutive activation of the protein by binding to the kinase domain and preventing it from interacting with other proteins. The molecule also inhibits the phosphorylation of other proteins, leading to tumor growth inhibition.</p>

<p>LDN 193188 is a synthetic peptide that is an activator of the N-methyl-D-aspartate (NMDA) receptor, a ligand to the NMDA receptor, and an inhibitor of the AMPA receptor. It is a potent agonist of the NMDA receptor and has no affinity for other receptors. LDN 193188 is a high purity reagent with CAS No. 1267610-30-9. The antibody reacts with human, mouse, rat, rabbit, hamster, bovine, guinea pig and goat proteins.</p>

<p>Cytochrome P450 14a-demethylase inhibitor 1I is a research tool used in the study of cell biology and pharmacology. The inhibition of cytochrome P450 14a-demethylase by this compound prevents the oxidative metabolism of drugs, including testosterone, progesterone, and cortisol. This inhibitor has been shown to be selective for cytochrome P450 14a-demethylase over other cytochrome P450 enzymes. Cytochrome P450 14a-demethylase inhibitor 1I binds to the active site of cytochrome P450 14a-demethylase, which is located on the outer mitochondrial membrane. It also binds to Ligand binding sites on Receptors and Peptides. Cytochrome P450 14a-demethylase inhibitor 1I can activate certain ion channels, such as TRPC6 channels, by increasing intracellular calcium levels. It also activates G protein-coupled receptors and inhibits protein interactions</p>

<p>CB-7921220 is a molecule with cell-free, conformation, and cyclase activity. It is an inhibitor of the cyclase enzyme that catalyzes the conversion of ATP to cAMP. The binding of CB-7921220 to the catalytic site of cyclase prevents the conversion of ATP to cAMP, which leads to decreased levels of intracellular cAMP. The inhibition of this enzyme may lead to reduced inflammation, pain, and fever symptoms. CB-7921220 has been shown to inhibit both isoforms (alpha and beta) of adenylyl cyclase in vitro. This drug is a competitive inhibitor that binds only when ATP is present at high concentrations.</p>

<p>Binds to microtubules</p>

<p>Urocortin 3 (Mouse, Rat)-EIA Kit is a first-generation, solid-phase sandwich ELISA kit for the quantitative measurement of mouse and rat urocortin 3. The kit contains all the necessary reagents for performing the assay, including antibodies and standards. <br>The Urocortin 3 (Mouse, Rat)-EIA Kit has been validated with mouse and rat samples and shown to be linear over a wide range of concentrations. The detection limit is 0.5 pg/ml in ELISA plates coated with 100 ng/ml of mouse or rat urocortin 3 antibody.</p>

<p>PX-866-17OH is a research tool that can be used as an activator or ligand. It has been shown to bind to the receptor with high affinity and specificity. PX-866-17OH also binds to cells, which may be due to its ability to inhibit ion channels. In addition, PX-866-17OH has been shown to inhibit the activity of enzymes involved in protein synthesis and cell growth.</p>

<p>Iso-H7 is a protein that belongs to the group of growth factors. It is an incompletely folded form of epidermal growth factor (EGF) that is able to bind to EGF receptors in cell membranes. Iso-H7 has been shown to have regulatory, pleiotropic, and cellular activities. It can be used as an antigen for the production of monoclonal antibodies, as well as for the development of drugs against viral infections and cancer. Iso-H7 stimulates cellular growth by activating phosphatase activity and inhibiting epidermal growth factor receptor phosphorylation in response to epidermal growth factor binding.</p>

<p>CC-671 is a synthetic compound that has been shown to have potent anticancer activity. It has been shown to be localized in the bladder, as well as other tissues, and to inhibit cancer stem cell growth. CC-671 inhibits multidrug resistance by blocking the ABCG2 transporter, which is responsible for efflux of chemotherapeutic drugs from cells. CC-671 also inhibits splicing by sequestering the human protein SRPK2, which is an abcg2 substrate that regulates mRNA production and protein synthesis. This inhibition leads to a decrease in cancer cell proliferation and survival.</p>

<p>Vasopressin is a peptide hormone that is synthesized from the amino acid arginine and stored in vesicles. It is released into the bloodstream by the hypothalamus, where it acts as an antidiuretic and also stimulates vasoconstriction and contraction of smooth muscle. Vasopressin has been shown to inhibit the binding of ligands to their receptors, which may be due to its ability to activate these receptors. This protein has been used as a research tool for studying receptor-ligand interactions, cell biology, and pharmacology. It can also be used as a reagent for Western blotting or immunohistochemistry.</p>

<p>Andrographiside is a sesquiterpene lactone that is extracted from the plant Andrographis paniculata. It has been shown to have chemiluminescence activity and inhibition of drug transporter activity in vitro. This compound is not well-studied, but has been shown to have biological properties such as hepatoprotective effects in rats.</p>

<p>Momelotinib mesylate is a potent, selective inhibitor of PD-L1. It has been shown to inhibit the expression of PD-L1 in vitro and in vivo. Momelotinib mesylate binds to the B7-H1 protein found on cells that line blood vessels, which is a protein target for tumor cells. It also inhibits the proliferation of cancer cells and may lead to their death. Momelotinib mesylate has been approved by the FDA as a treatment method for patients with myelofibrosis who have had no success with other treatments. This drug is given orally and can be used together with other medications such as steroids or erythropoietin. It has been shown to reduce organ damage and improve quality of life in these patients.</p>

<p>Obestatin is a neuropeptide that was first isolated from the mouse and rat hypothalamus. The Obestatin (Mouse, Rat)-EIA Kit is an in-house ELISA assay for the detection of mouse and rat obestatin. This kit can be used to detect obestatin in serum, plasma, or cell culture supernatant samples. It is a useful tool for studying the role of this peptide in various biological processes.</p>

<p>QL9 is a peptide that binds to light and has been shown to activate cells in the immune system. QL9 is a specific agonist for both CD4+ and CD8+ T cells and can be used as an adjuvant in a cell vaccine. The binding of this peptide to light activates T cells, which then produce cytokines such as IFN-γ, IL-2, and IL-12. It has been shown that QL9 can activate CD4+ T cells in the absence of antigen stimulation or antibody co-stimulation. This peptide also selectively binds to lipids, which are necessary for its function.</p>

<p>AC-93253 iodide is a drug that is being developed for the treatment of prostate cancer. The mechanism of action of AC-93253 iodide is still not known, but it has been shown to inhibit epidermal growth factor (EGF) receptor proliferation in prostate cancer cells and suppress the proliferation of other cancerous cells. Clinical studies have demonstrated that this drug has anti-leukemic activity, and it was shown to be effective against a wide variety of cancers in vitro. AC-93253 iodide inhibits transcriptional regulation by binding to the polymerase chain reaction (PCR) transcriptase during DNA replication. This inhibition prevents the extension of DNA chains and halts DNA synthesis.</p>

<p>Negative control for endo-IWR-1</p>

<p>NK 314 is a potent anticancer agent that belongs to the class of nitidine-based compounds. It has been shown to be effective in inhibiting the growth of cancer cells in human cancer cell lines and has also been shown to inhibit the growth of cancerous tumors in animal models. NK 314 is a cytotoxic agent that targets DNA replication, leading to cell death by apoptosis. This compound also inhibits the production of nitric oxide, which is a mediator for the inflammatory response in many cancers. NK 314 has demonstrated antitumor effects in vitro and in vivo, making it an attractive potential therapeutic candidate for treatment of various types of cancer.</p>

<p>Retinoic acid receptor (RARα) agonist; induces cell differentiation</p>

<p>TC HSD 21 is a research tool that can be used as an inhibitor in the study of ion channels, ligand-receptor interactions and protein interactions. TC HSD 21 is a peptide with high purity. The IC50 for TC HSD 21 ranges from 1 nM to 100 nM. TC HSD 21 has been shown to activate receptors, inhibit ion channels and act as a ligand for peptide receptors.</p>

<p>FRETS-25Val is a research tool that is used to activate, inhibit, or modulate the function of ion channels. FRETS-25Val is an agonist of G protein-coupled receptors (GPCRs) and ligands for receptor tyrosine kinases (RTKs). It has been shown to bind to Ligand Binding Domains (LBDs) on cell surface receptors. FRETS-25Val binds to antibody Fc regions and also inhibits the binding of peptides to proteins by competing with them for binding sites.</p>

<p>IMR-1 is a small molecule that inhibits the growth of cancer cells by inducing apoptosis. It disrupts cell function, leading to the inhibition of tumor growth and metastasis. IMR-1 also has a regulatory effect on various cellular processes, such as cell differentiation and proliferation. IMR-1 induces the polymerase chain reaction (PCR) in living cells, which leads to integrating DNA fragments into the genome. This process can be used to diagnose tumors and monitor their progression in vivo.</p>

<p>Indophagolin is a research tool used in cell biology and pharmacology. Indophagolin binds to the receptor site of ion channels, which regulates the flow of ions across the membrane. It is also an inhibitor that prevents ligands from binding to their receptors. This product is available as a high-purity liquid at a concentration of 10 mg/mL in 15 mL vials.</p>

<p>Lysyl-bradykinin is a potent activator of human bradykinin receptors. It is an inhibitor of protein interactions and has a high purity with CAS number 59814-34-8.</p>

<p>GW 280264X is a research tool that can be used to study the activation of receptors. It is an agonist of G-protein coupled receptor, which activates or inhibits the activity of ion channels. GW 280264X has been shown to inhibit the binding of an antibody to its antigen and also inhibits cell proliferation by reducing protein synthesis in cells. GW 280264X is a very high purity product that is provided in liquid form for use in research.</p>

<p>NCX899 is a novel drug that binds to the AT1 receptor and blocks the signaling of angiotensin II. It is an antagonist that has been shown to reduce blood pressure in animal models by preventing the binding of angiotensin II to its receptors in the carotid artery, thereby reducing vascular tone. The pharmacokinetics of NCX899 were studied in rats and dogs. The compound was found to be well absorbed after oral administration, with a tmax at 1-2 hours and a half-life of 3-4 hours. In rats, NCX899 showed inhibition of angiotensin converting enzyme (ACE) activity and tissue ACE levels. In addition, it was found to have high bioavailability, with only low plasma protein binding (less than 10%).</p>

<p>Selective Raf inhibitor</p>

<p>Profoxydim lithium salt is a peptide that can be used as a research tool in cell biology, pharmacology, and other fields. Profoxydim lithium salt is an activator of ion channels, which are membrane proteins that control the flow of ions in and out of cells. It has also been shown to inhibit the activity of protein interactions with receptors and ligands. Profoxydim lithium salt is not active against any known receptor or ligand.END&gt;</p>

<p>KLH45 is a lanthanum compound that has been shown to be reactive with human serum. KLH45 is an antibody response enhancer that has been shown to increase the production of antibodies in vitro. It is also a chemoproteomic agent and can be used for the profiling of fatty acids. KLH45 is homologous to the gene product, which is involved in human immunodeficiency. KLH45 has been synthesized using fatty acids as well as other methods such as cell culture, chemical synthesis, and enzymatic synthesis. The health effects of this compound are not yet fully known.</p>

<p>Arg-AMS is a ligand that has been shown to activate receptors. The receptor for Arg-AMS is an ion channel, which is a protein that conducts ions through a cell membrane, thereby creating an electrical current. This ligand can be used as a research tool in order to study the function of ion channels. It can also be used to develop antibodies against the receptor, and to identify possible inhibitors of this receptor. Arg-AMS has been shown to inhibit the binding of proteins to each other, and may be useful in understanding protein interactions in cells.</p>

<p>Voltage-gated sodium channel blocker; quaternary derivative of lidocaine</p>

<p>TGF-? type I receptor antagonist; anti-cancer agent</p>

<p>FT671 is an antibody that binds to the extracellular domain of the human angiotensin II type 1 receptor. It has been shown to inhibit the binding of angiotensin II to its receptor and block the activation of signaling pathways in cells. FT671 can be used as a research tool for studying peptides, cell biology, pharmacology, protein interactions, and ion channels. The antibody is also a ligand that can activate receptors by binding to them.</p>

<p>TG MS Calibrator-8 is a high quality, quantitated heavy/light peptide calibrator for Mass Spectroscopy research. Thyroglobulin is a protein which is produced by the thyroid and is a precursor to thryoid hormones.</p>

<p>3,6,9,12,15,18,21-Heptaoxatricosanedioic acid is a peptide that can be used as a research tool in cell biology and pharmacology. It is also an inhibitor of ion channels and receptor. 3,6,9,12,15,18,21-Heptaoxatricosanedioic acid binds to the ligand binding site of the receptor and inhibits receptor activation. This compound has been shown to activate potassium channels and inhibit sodium channels in some studies. 3HATDAD has been shown to bind to antibodies with high affinity.</p>

<p>Stigmasterol-d5 is a potent and specific activator of the ion channels TRPV1 and TRPA1. It is also an inhibitor of the ligand-gated ion channel, nicotinic acetylcholine receptor (nAChR). Stigmasterol-d5 binds to the protein, with a K d of 0.06 μM. The binding affinity is higher than that of capsaicin, which has a K d of 0.05 μM. This compound has been used as a research tool in cell biology and neuroscience studies.</p>

<p>Serum Thymic Factor (FTS) is a glycoprotein that regulates the development of T-lymphocytes. FTS has been shown to interact with ion channels, receptors, and ligands. It is used in pharmacology research as a tool for studying protein interactions and in cell biology research to study the activation of cells. Serum Thymic Factor (FTS) is a recombinant protein with high purity and high specific activity. It can be used as an antibody or as an inhibitor in research studies.</p>

<p>Please enquire for more information about Bis(4-trifluoromethylphenyl)(4-carboxyphenyl)phosphine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Monoglyceride lipase is a recombinant human enzyme used as a research tool in pharmacology, cell biology and other life sciences. It is used to study the molecular mechanisms of lipid metabolism, signal transduction, and receptor-ligand interactions. Monoglyceride lipase has been shown to activate various peptides by hydrolyzing their ester bonds. It can also be used as an antibody against the peptide substrate. This enzyme has a high purity and is supplied with a CAS Number for quality control purposes.</p>

<p>The IL-3R is a cytokine receptor that binds to the interleukin 3 (IL-3) molecule. The protein has a molecular weight of approximately 40 kDa and consists of two extracellular immunoglobulin-like domains, a transmembrane domain, and an intracellular tyrosine kinase domain. The IL-3R is expressed on hematopoietic stem cells, progenitor cells, erythrocytes, mast cells, neutrophils, lymphocytes and macrophages.</p>

<p>Please enquire for more information about 4-[D10]Leu-M1 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cefuroxime is a broad-spectrum antibiotic that belongs to the group of antibiotics called cephalosporins. Cefuroxime acts by inhibiting bacterial cell wall synthesis and is effective against many Gram-positive and Gram-negative bacteria, including Pseudomonas aeruginosa. Cefuroxime is available in the form of an anhydrous, crystalline powder for oral administration. It has two stereoisomers, which are designated L-cefuroxime (L) and D-cefuroxime (D). The L form is more active than the D form. The L-form also has a higher yield in reactions with magnesium ions than the D form.</p>

<p>1,2-Dioctanoyl-sn-Glycero-3-Phosphatidylcholine is a prodrug that is hydrolyzed by hydrochloric acid to form 1,2-dioctanoylglycerol. The fatty acid chain of the product has been shown to be a PGP substrate and an inhibitor of PGP. As an inhibitor, this drug blocks the efflux of certain substrates from cells. This drug has also been shown to have inhibitory properties against calcium binding and disulfide bond formation. 1,2-Dioctanoyl-sn-Glycero-3-Phosphatidylcholine has been used in assays to study the inhibition of the pore size and ion selectivity of various membranes.</p>

<p>Phosphatidylcholine (PC) is a phospholipid that is an important component of biological membranes. It is composed of choline and fatty acids, the most common being C16-20:4. PC is synthesized by the enzyme lecithin:cholesterol acyltransferase (LCAT). The synthesis of PC requires acetylation, which can be performed by a number of different enzymes. PC has been shown to have anti-apoptotic effects and has been found to inhibit platelet activation in vivo. PC also activates macrophage-like cells, which may be due to its oxidation products.</p>

<p>SPAI-1 is a protein that belongs to the group of activator proteins. It is an activator of the N-type calcium channels. SPAI-1 interacts with the receptor and peptides, which are involved in signal transduction pathways. SPAI-1 has been shown to be a high purity ion channel ligand that can be used as a research tool for cell biology and pharmacology studies.</p>

<p>Ertiprotafib is a natural drug that inhibits the activity of enzymes involved in the synthesis of fatty acids and proteins. Ertiprotafib has been shown to inhibit phosphatase, acetylcholinesterase, hydroxylase, and phosphodiesterase. The inhibition of these enzymes leads to an increase in messenger RNA levels and protein production by cells. This drug also has anti-cancer properties. Clinical studies have shown that Ertiprotafib improves diabetic patients’ glucose tolerance and reduces insulin resistance.</p>

<p>Mesm is a fatty acid that has been shown to induce apoptosis in murine hepatoma cells. The optical properties of Mesm are dependent on the concentration and type of fatty acid, which can be used as an actuator for optical sensors. The dry weight of Mesm is 3,500 g/kg. Mesm has been shown to have anti-inflammatory effects in mice with autoimmune diseases. It also has the ability to induce pluripotency in mammalian cells, including human embryonic stem cells and induced pluripotent stem cells.</p>

<p>C-Jun is a protein that belongs to the AP-1 transcription factor family. It has been shown to inhibit the growth of cancer cells and induce apoptosis. C-Jun (1-79) binds to bortezomib, which is a proteasome inhibitor, and prevents it from binding to the 20S proteasome. This in turn inhibits protein degradation, leading to cell death by apoptosis. The effect of C-Jun (1-79) on prostate cancer cells has been studied in vitro with hepg2 cells and in vivo with an implantation of stents into rat liver cells. In these studies, C-Jun (1-79) inhibited cell proliferation and induced apoptotic cell death.</p>

<p>PD-1/PD-L1 inhibitor 3 is an activating molecule that binds to PD-L1, inhibiting its interaction with the inhibitory receptor PD-1. This drug is a small molecule that blocks the binding of PD-L1 and PD-1, which prevents the inhibition of T cell proliferation and function. In this way, PD-L1 inhibitor 3 activates T cells and enhances anti-tumor activity by preventing tumor escape from immune surveillance. Approved in 2017, this drug has been shown to be safe in patients with non-small cell lung cancer (NSCLC) and other types of cancer. The most common side effects are fatigue, diarrhea, nausea, vomiting, rash, constipation, headache, fever, cough and decreased appetite.</p>

<p>MG 624 is a biofungicide, which is derived from naturally occurring microorganisms with a complex enzymatic mode of action. This product employs a consortium of beneficial microbes that produce enzymes capable of degrading the cell walls of various plant pathogens, thus preventing their spread and growth.</p>

<p>2-[(4S)-4-[[5-(Dimethylamino)naphthalen-1-yl]sulfonylamino]-5-(4-methylpiperidin-1-yl)-5-oxopentyl]guanidine (KW6002) is a high purity, water soluble, white powder. It has been used as a research tool in receptor and ligand binding studies to investigate the interaction of KW6002 with peptide receptors and membrane proteins. This product has also been used as an inhibitor of protein interactions.</p>

<p>Mambalgin-1 is a peptide that can be used as a research tool to study the function of ion channels and receptor proteins. It is an activator of potassium ion channels, which are involved in the regulation of cell membrane potential. Mambalgin-1 also binds to serotonin receptors, which are involved in the transmission of nerve impulses. The peptide's affinity for different types of receptors suggests it may have therapeutic potential for treating disorders such as depression and schizophrenia.</p>

<p>Tc ot 39 is a molecule that can be used as a transcriptional regulator. The drug has been shown to be effective in clinical studies for the treatment of cancer and chronic viral diseases, such as hepatitis C. Tc ot 39 binds to the microglia receptor (OX2R) and inhibits the production of pro-inflammatory cytokines. It also inhibits the production of inflammatory cytokines such as tumor necrosis factor-α (TNF-α), interleukin 1β (IL-1β), and IL-6 by inhibiting phosphorylation of Janus kinase 2 (JAK2). Tc ot 39 also has an effect on depression, which may be due to its ability to inhibit oxidative stress in brain cells.</p>

<p>C-Peptide (Mouse)-EIA Kit is a mouse C-peptide EIA kit. It is designed for the quantitative measurement of C peptide in serum samples from mice. The kit contains an antibody that recognizes mouse C peptide, and a conjugate that binds to the antibody. The kit also contains a biotin-labeled anti-mouse IgG antibody, which reacts with the conjugate to form a complex that is subsequently detected by an enzyme-conjugated streptavidin. The amount of complex formed is proportional to the amount of C peptide present in the sample.</p>

<p>LE 300 is a cutting-edge biopesticide, which is derived from naturally occurring microbial sources. This formulation exploits the bioactive compounds produced by specific microorganisms to disrupt the physiological processes of target pests. The mode of action involves the inhibition of essential metabolic pathways, leading to the eventual mortality of these pests. This mechanism makes it an effective tool in integrated pest management programs that aim to minimize chemical pesticide use.</p>

<p>Dipeptidyl-peptidase IV (DPP4) is a complex enzyme that is expressed in the pancreas and regulates glucose-dependent insulinotropic polypeptides. DPP4 cleaves the amino terminal dipeptide from these polypeptides, which prevents the activation of pancreatic β-cells. The recombinant human form of this enzyme has been shown to activate T cells and induce apoptosis in insect cells. Its activity against chemokines in vitro may be due to its ability to cleave glycosylated polypeptides. This enzyme also has anti-inflammatory effects by inhibiting the production of proinflammatory cytokines such as tumor necrosis factor α (TNFα), interleukin 1β (IL1β), and IL6.</p>

<p>Gly-Pro-AMC is a peptide that can be used as a research tool to investigate protein interactions. Gly-Pro-AMC is an activator of ion channels and is able to inhibit ligand binding to receptor. It has been used in pharmacology for the study of protein interactions, ion channels, and receptors. Gly-Pro-AMC binds to the cell membrane and blocks the activation of potassium channels. It also inhibits ligand binding to receptors. This compound has been found in high purity with a CAS number of 67341-42-8.</p>

<p>Peptide H-KHKHKHKHKHKHKHKHKHKKLFKKILKYL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Please enquire for more information about Thymosin-b4 Human Recombinant including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Yubeinine is a natural product with hepatoprotective effects. It is obtained from the leaves of Yubae, a plant native to China and Japan. The active principle of yubeinine has been identified as 3-O-acetyl-11β-hydroxyyubaeoside (3AHY) which exerts its pharmacological effect by inhibiting the synthesis of fatty acids in the liver cells. In vitro studies have shown that yubeinine inhibits the secretion of inflammatory cytokines and chemokines, which are responsible for liver damage. This medicine also has an anti-inflammatory property and protects against oxidative stress in mice with hepatitis. Yubeinine has not been studied in humans, but it can be used as a supplement for people with chronic hepatitis or other liver diseases.</p>

<p>RG-12525 is an engineered compound designed for targeted genetic modification, which is synthesized from recombinant DNA technology. With precise gene-editing capabilities, it utilizes CRISPR-Cas9 as its mode of action, enabling specific gene sequences to be accurately cut and modified within a variety of eukaryotic cells. The compound's mechanism involves guiding RNA that pairs with target DNA sequences, allowing the Cas9 enzyme to introduce double-strand breaks, which facilitate desired genetic alterations through cellular repair pathways.<br><br>This compound is utilized predominantly in genetic engineering and functional genomics studies. RG-12525 enhances the ability to investigate gene function, develop gene therapies, and create genetically modified organisms for research purposes. Its applications extend to agricultural biotechnology, where it aids in the development of crops with enhanced traits, and to biomedical research, where it contributes to the understanding of genetic diseases and the development of potential treatments.</p>

<p>Hypolipidemic agent</p>

<p>PP2 is a member of the PP2A protein phosphatase family. It is an inhibitor of the catalytic subunit of PP1, which is involved in the regulation of cell signaling pathways. This inhibitory effect is achieved by binding to the regulatory subunits of PP1 and competitively inhibiting their ability to bind to the catalytic subunit. The binding site for this inhibitor has been identified as a hydrophobic pocket. The PP2 analogs are used as research tools and activators for antibody production in research laboratories, and can be obtained from commercial suppliers.</p>

<p>TM5007 is a molecule that has been shown to have a predictive biomarker for cancer. The acyl chain of TM5007 has been shown to be an important determinant for the biological activity of this molecule. TM5007 is orally bioavailable and can be used as a structural analysis tool for predicting the efficacy of other molecules. TM5007 inhibits the growth factor-induced proliferation of cardiac cells, and also blocks cardiomyocyte hypertrophy in vitro. It has also been shown to inhibit serine protease activity in cell culture experiments, which may provide a mechanism for its anticancer effects.</p>

<p>Please enquire for more information about AKT kinase inhibitor hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>ZT-12-037-01 is a potential drug for the treatment of malignant melanoma. This drug is a phosphoramidate prodrug that is activated by an enzyme known as cytidine deaminase, which converts it to an active form of 5′-fluoro-5′-deoxycytidine. ZT-12-037-01 has been shown to inhibit the growth of malignant melanoma cells, and also induces cell death in these cells. ZT-12-037-01 also inhibits tumor progression in mice with preclinical models of cancer and research on this drug has helped advance our understanding of this disease.</p>

<p>VU0486846 is a novel, non-competitive, allosteric modulator of nicotinic acetylcholine receptors. It is a potent inhibitor of the high-affinity choline uptake system and prevents the accumulation of acetylcholine in tissues. VU0486846 has shown efficacy in preclinical models in which it was able to enhance responsiveness to acetylcholine. As an allosteric modulator, VU0486846 binds to a different site on the receptor than acetylcholine, and thereby reduces the number of acetylcholine molecules required for activation. This pharmacokinetic profile could potentially allow for lower doses of this drug to be administered, with fewer side effects.</p>

<p>ML150 is a chemical compound, which is a synthetic molecule developed through advanced organic synthesis. The product operates as an allosteric inhibitor of a specific enzyme, modulating its activity through non-competitive binding. This mechanism allows for a highly selective interaction with the enzyme, altering its conformation and thereby influencing its function in a controlled manner.</p>

<p>Bitopertin is a glycine reuptake inhibitor, which is sourced from the development of selective central nervous system agents. It works by inhibiting the glycine transporter type 1 (GlyT1), thereby increasing extracellular glycine levels, particularly in regions with high densities of NMDA receptors. This modulation of glycine levels plays a crucial role in enhancing NMDA receptor function, which is pivotal for synaptic plasticity and neurotransmission.</p>

<p>Rasagiline-13C3 is a medicinal product that belongs to the group of inhibitors. It has been shown to have potent anticancer properties and can be used for the treatment of tumors in humans. Rasagiline-13C3 works by inhibiting the activity of kinases, which are enzymes that play a crucial role in cancer cell growth and division. This drug is an analog of polysaccharides found in Chinese medicine, which have been traditionally used for their medicinal properties. Rasagiline-13C3 induces apoptosis, a process of programmed cell death, in cancer cells and prevents their proliferation. This drug has also been detected in urine samples after administration, indicating its potential use as a diagnostic tool for cancer detection.</p>

<p>GDC046 is a triazole compound with inhibitory properties that acts as a tyrosine kinase inhibitor. It binds to the active site of the enzyme and prevents ATP from binding, inhibiting the enzyme's activity. GDC046 has shown efficacy in vitro against several cancer cell lines and has been found to be safe in vivo. GDC046 has also been found to be selective for the target enzyme, which minimizes off-target effects.</p>