Produits biochimiques et réactifs
Sous-catégories appartenant à la catégorie "Produits biochimiques et réactifs"
- Biomolécules(98.572 produits)
- Par Biological Target(100.755 produits)
- Par usage/effets pharmacologiques(6.938 produits)
- Cryoconservation et composés associés aux cryoconservateurs(21 produits)
- Désinfectants, additifs pour les fluides pour bains chauffants et composés apparentés(28 produits)
- Hormones(467 produits)
- Biologie végétale(6.906 produits)
- Métabolites secondaires(14.368 produits)
130507 produits trouvés pour "Produits biochimiques et réactifs"
UNC-926
CAS :UNC-926 is a synthetic molecule that can act as a transcriptional regulator. It interacts with lysine residues in the regulatory proteins of pluripotent stem cells, which are responsible for the regulation of their activity. This interaction leads to conformational changes in the protein, which in turn affects its ability to regulate gene expression. UNC-926 has been shown to be active against viruses such as HIV and influenza A virus. In addition, it has been shown to inhibit the replication of these viruses by methylating specific sites on chromatin-bound DNA. UNC-926 is also a potent inhibitor of methyltransferase enzymes, which are involved in post-translational modifications of immunodeficiency regulatory proteins (IRP). It inhibits methylation at specific sites on IRP molecules and prevents them from binding to RNA polymerase II and III, inhibiting transcription of viral genes.Formule :C16H21BrN2ODegré de pureté :Min. 95%Masse moléculaire :337.25 g/molAZD 8835
CAS :PI3Kα and PI3Kδ inhibitor
Formule :C22H31N9O3Degré de pureté :Min. 95%Masse moléculaire :469.54 g/mol1-Hexanoyl-2-hydroxy-sn-glycero-3-phosphocholine
CAS :1-Hexanoyl-2-hydroxy-sn-glycero-3-phosphocholine is a lysophosphatidylcholine that is formed by the hydrolysis of phospholipids containing 1 hexanoic acid. The lipid is incorporated into the cell membrane and has been shown to inhibit the growth of bacteria by altering the permeability of the membrane. This lipid may be used as a therapeutic agent for bacterial infections.Formule :C14H30NO7PDegré de pureté :Min. 95%Masse moléculaire :355.36 g/mol[Sar1,Ile8]-Angiotensin II
Angiotensin II is a peptide that acts as an agonist of the angiotensin receptors. It is a hormone that regulates blood pressure and fluid balance. The antagonist can block the effects of the peptide, which may be useful in treating cardiovascular diseases such as hypertension and congestive heart failure.Formule :C46H73N13O10•CH3COOH•4H2ODegré de pureté :Min. 95%Masse moléculaire :1,100.26 g/molML241 hydrochloride
CAS :ML241 hydrochloride is a small molecule inhibitor, which is synthesized specifically for laboratory research purposes. It originates from chemical synthesis processes aimed at producing highly selective inhibitors for biochemical pathways. This compound is known for its role in inhibiting oxysterol-binding protein (OSBP), thereby interfering with lipid signaling pathways within cells.Formule :C23H25ClN4ODegré de pureté :Min. 95%Masse moléculaire :408.92 g/molIbrutinib-MPEA
CAS :Ibrutinib-MPEA is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK). BTK is an enzyme that regulates the activity of other enzymes and proteins involved in B cell signaling. Ibrutinib-MPEA inhibits the binding of Bruton's tyrosine kinase to its ligands, preventing it from functioning as an activator protein. This inhibition prevents activation of downstream signaling pathways that lead to cell proliferation, antibody production, and cytokine secretion. Ibrutinib-MPEA binds to BTK with high affinity and specificity.Formule :C32H39N9O2Degré de pureté :Min. 95%Masse moléculaire :581.7 g/molIcotinib Hydrochloride
CAS :Icotinib hydrochloride is a drug that inhibits the activity of several signal pathways in cancer cells. It is a potent, selective inhibitor of vascular endothelial growth factor receptor (VEGFR) and platelet-derived growth factor receptor beta (PDGF-Rβ) with long-term efficacy. Icotinib hydrochloride has been shown to be effective against lung cancer and colorectal adenocarcinoma. This drug also has not shown any significant side effects in clinical trials, which may be due to its low toxicity.Formule :C22H22ClN3O4Degré de pureté :Min. 95%Masse moléculaire :427.88 g/molPraliciguat
CAS :Praliciguat is a drug that has the potential to be used in the treatment of chronic pulmonary diseases. It is a soluble guanylate cyclase (sGC) stimulator, which can promote the release of nitric oxide from endothelial cells. Praliciguat also increases insulin sensitivity and improves cardiac function in patients with chronic heart failure. This drug has been shown to have beneficial effects on hepatic steatosis and insulin resistance in experimental animals. Praliciguat has also been shown to improve insulin sensitivity, reduce inflammation, and inhibit viral replication in animal models of type 1 diabetes.
Formule :C21H14F8N6O2Degré de pureté :Min. 95%Masse moléculaire :534.36 g/molPD-1-IN-18
CAS :PD-1-IN-18 is a small molecule inhibitor that targets the programmed cell death protein 1 (PD-1), which is derived through synthetic pathways. Its primary mode of action involves disrupting the interaction between PD-1 and its ligand, PD-L1, a process critical in the regulation of immune responses. By blocking this interaction, PD-1-IN-18 enhances T-cell activity and contributes to an increased immune response against tumors.Formule :C11H17N5O8Degré de pureté :Min. 95%Masse moléculaire :347.28 g/molCystatin SN, human, recombinant
Cystatin SN is a cysteine protease inhibitor that is involved in the regulation of protein catabolism and inflammation. Cystatins are natural inhibitors of cystein proteases, which are involved in the degradation of proteins. Cystatin-S can inhibit the activity of various cysteine proteases, including cathepsin B, cathepsin L, and papain. The recombinant human form of Cystatin SN has been shown to inhibit various ion channels such as calcium channels and potassium channels. It also inhibits the activation of other molecules by binding to them. This inhibition may be due to its ability to bind with receptors on cells or its ability to bind with ligands.Degré de pureté :Min. 95%Phenol hydrobromide, 3-[2-(diproplyamino)ethyl]
CAS :Phenol hydrobromide is a chemical that inhibits plant metabolism by binding to the enzyme alcohol dehydrogenase, which catalyzes the conversion of alcohols to aldehydes and ketones. Phenol hydrobromide has been shown to inhibit the production of energy in wild-type yeast cells when they are grown at high concentrations. The optimum concentration for this inhibitor is 10 mM. Phenol hydrobromide has also been shown to inhibit the polymerase chain reaction (PCR) in vitro. This inhibition may be due to its ability to form hydrogen bonds with water molecules or its basic structure.
Formule :C14H24BrNODegré de pureté :Min. 95%Masse moléculaire :302.25 g/molINT 131
CAS :INT 131 is an estrogen receptor modulator that has been shown to have a proton-pump inhibitor effect. It has the potential to be used in the treatment of bowel disease, cancer, or diabetes. INT 131 inhibits the growth of colon cancer cells in vitro and in vivo by inducing cell lysis and inhibiting inflammatory cytokines. It also has an inhibitory effect on oral hypoglycemic agents and anti-inflammatory drugs. INT 131 is a drug repositioning candidate with possible applications for treating inflammatory diseases such as inflammatory bowel disease or insulin resistance.
INT 131 is a drug repositioning candidate with possible applications for treating inflammatory diseases such as inflammatory bowel disease or insulin resistance.Formule :C21H12Cl4N2O3SDegré de pureté :Min. 95%Masse moléculaire :514.2 g/molKY-226
CAS :KY-226 is a synthetic chemical compound, which is a derivative developed through organic synthesis techniques. It is designed to function as a targeted enzyme inhibitor, specifically binding to its enzyme of interest to modulate its activity. This interaction is achieved via competitive inhibition, where KY-226 competes with the natural substrate for binding sites on the enzyme's active site.
Formule :C27H31NO3S2Degré de pureté :Min. 95%Masse moléculaire :481.7 g/molRO462005
CAS :RO462005 is a synthetic compound that has been shown to have physiological effects on cardiac tissues and the cardiovascular system. It binds to the receptor of the G-protein, which is coupled to a phospholipase C (PLC) cascade. RO462005 activates PLC, which leads to an increase in intracellular calcium levels and activation of protein kinase C (PKC). This activity leads to vasodilation and increased blood flow. RO462005 has been shown to inhibit transcription-polymerase chain reaction (PCR) by binding to RNA polymerase II, inhibiting transcription of messenger ribonucleic acid (mRNA). It inhibits proliferation of human colon adenocarcinoma cells (CCaco-2) in vitro by binding with high affinity to their PDE4D5 receptor. RO462005 also increases contractions in vitro in response to acetylcholine or potassium chloride by stimulating muscarinic receptors on ileal smooth muscle cells fromFormule :C23H27N3O6SDegré de pureté :Min. 95%Masse moléculaire :473.54 g/molrac Trans-4-cotinine carboxylic acid methyl ester
CAS :Rac trans-4-cotinine carboxylic acid methyl ester is a peptide that is an activator of the protein Rho. Rac trans-4-cotinine carboxylic acid methyl ester mimics the action of the natural regulator, cotranslationally activating Rho by binding to its GTPase domain. Rac trans-4-cotinine carboxylic acid methyl ester has been shown to inhibit ion channels and ligand-gated channels, as well as modulate the activity of other proteins involved in cell division. Rac trans-4-cotinine carboxylic acid methyl ester is not toxic to cells and can be used as a research tool for studying cellular biology and receptor function.
Formule :C12H14N2O3Degré de pureté :Min. 95%Masse moléculaire :234.25 g/mol(2-((3-Hexyl-4-methyl-2-oxo-2H-chromen-7-yl)oxy)acetyl)methionine
CAS :(2-((3-Hexyl-4-methyl-2-oxo-2H-chromen-7-yl)oxy)acetyl)methionine is a synthetic small molecule that has been shown to activate K+ channels. It potentiates the effects of GABA, an inhibitory neurotransmitter, on neuronal excitability. This drug also binds to the glutamate receptor and inhibits its function. (2-(3-hexyl-4-methyl-2-oxo--2H chromen 7 yl)oxyacetyl)methionine is a research tool used in pharmacology and cell biology. It is used as an agonist in antibody production and as a high purity reagent for peptide synthesis.
Formule :C23H31NO6SDegré de pureté :Min. 95%Masse moléculaire :449.6 g/molML 786 Dihydrochloride
CAS :ML 786 Dihydrochloride is a pluripotent stem cell culture supplement that contains the following: 50% fetal bovine serum, 25% Dulbecco's Modified Eagle Medium, 10% horse serum, 10% human serum, and 5% dimethyl sulfoxide. It is used to support the growth of pluripotent cells.
Formule :C29H29F3N4O3•(HCl)2Degré de pureté :Min. 95%Masse moléculaire :538.56 g/molAmpicillin-d5
CAS :Ampicillin-d5 is a stable isotope-labeled antibiotic, which is a derivative of the β-lactam antibacterial agent ampicillin. This compound is synthesized by incorporating deuterium atoms, replacing certain hydrogen atoms, which aids in mass spectrometry analysis due to its distinct molecular weight.
Formule :C16H19N3O4SDegré de pureté :Min. 95%Masse moléculaire :354.4 g/molSB 202190 hydrochloride
CAS :Inhibitor of p38 MAPK kinaseFormule :C20H15ClFN3ODegré de pureté :Min. 95%Masse moléculaire :367.8 g/molResorcinolnaphthalein
CAS :Resorcinolnaphthalein is a non-steroidal anti-inflammatory drug that is used to treat chronic pulmonary diseases and other inflammatory conditions. Resorcinolnaphthalein has been shown to inhibit the production of proinflammatory cytokines such as IL-10, and also has the ability to modulate autophagy. It has been shown in vitro to activate the transcription of pro-inflammatory cytokines, chemokines, and adhesion molecules in response to lipopolysaccharides (LPS). Resorcinolnaphthalein also inhibits angiotensin II, which may be responsible for its antihypertensive effects. Transgenic animal studies have shown that resorcinolnaphthalein inhibits airway hyperresponsiveness and pulmonary hypertension induced by chronic cigarette smoke exposure.Formule :C24H14O5Degré de pureté :Min. 95%Masse moléculaire :382.4 g/mol14,15 β-Dihydroxyklaineanone
CAS :Quassinoids are a group of natural products that have been found in plants of the Simaroubaceae family. One example is 14,15-β-dihydroxyklaineanone. Quassinoids are biologically active compounds that have shown to have antiviral and cytotoxic properties. 14,15-β-Dihydroxyklaineanone has been found to inhibit the growth of a number of viruses including HIV, herpes simplex virus type 1, and influenza A virus. The extract of this compound has also been used for the treatment of leishmaniasis, an inflammatory disease caused by parasitic protozoa from the genus Leishmania. There is still much to be learned about the toxicity and safety profile of quassinoids as well as their analytical methods.
Formule :C20H28O8Degré de pureté :Min. 95%Masse moléculaire :396.4 g/molPep 2-8
CAS :Pep 2-8 is a cyclic peptide that induces autophagy, the process whereby cells destroy their own contents. Pep 2-8 has been shown to have beneficial effects on cardiac function and lowering low-density lipoprotein cholesterol (LDL-C). Pep 2-8 binds to the asialoglycoprotein receptor on the surface of liver cells, which allows it to be taken up by these cells. It also binds to a protein target in the cell membrane, which leads to increased uptake of Pep 2-8 by these cells. In addition, Pep 2-8 inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9) and increases LDL receptors on the cell surface. This leads to an increase in hepatic uptake of LDL particles from the bloodstream and decreased cholesterol levels in blood plasma.Formule :C83H110N16O24Degré de pureté :Min. 95%Masse moléculaire :1,715.9 g/molWEE1-IN-3
CAS :WEE1-IN-3 is a peptide inhibitor that binds to the ATP-binding pocket of WEE1. The binding site of this peptide is different from that of other inhibitors, such as GSK2606414 and Iressa, which bind to the ATP hydrolysis site. WEE1-IN-3 blocks the activation of WEE1 in response to DNA damage and inhibits cell proliferation by blocking protein synthesis. This peptide is a research tool for studying the role of WEE1 in many cellular processes, including ion channels and cell cycle regulation.Formule :C28H31N7O2Degré de pureté :Min. 95%Masse moléculaire :497.6 g/molN-Tetradecanoyl-D-homoserine lactone
CAS :N-Tetradecanoyl-D-homoserine lactone (TDCL) is a peptide that is used as a research tool to study protein interactions. TDCL binds to ion channels and inhibits the opening of these channels by interacting with the receptor, ligand, or other proteins. TDCL also binds to antibodies and can be used for immunological purposes. TDCL has been shown to inhibit the production of inflammatory cytokines in macrophages and reduce the expression of pro-inflammatory genes in human cells. TDCL has been shown to inhibit the binding of ligands to their receptors by competitive inhibition, leading to its use as a pharmacological agent.Formule :C18H33NO3Degré de pureté :Min. 95%Masse moléculaire :311.46 g/molGSK2643943A
CAS :GSK2643943A is an investigational drug, which is a product of GlaxoSmithKline's extensive research efforts. It is a small molecule inhibitor targeting specific cellular pathways involved in tumor growth and proliferation. This compound is designed to selectively inhibit kinase signaling, a process critical for the survival and metastasis of cancer cells. By disrupting these pathways, GSK2643943A aims to impede cancer progression, offering a potential new avenue for therapeutic intervention in oncology.Formule :C17H12FN3Degré de pureté :Min. 95%Masse moléculaire :277.29 g/mol2-Aminomethyl-4-t-butyl-6-iodophenol
CAS :2-Aminomethyl-4-t-butyl-6-iodophenol (2AMI) is a drug used to treat inflammation in the urinary tract and for the treatment of hypertension. 2AMI has been shown to be an effective inhibitor of the transport of calcium into cells, which results in the inhibition of cellular processes such as protein synthesis. It also has significant anti-inflammatory activity. 2AMI was found to block inflammatory reactions by inhibiting neutrophil migration, which is an important step in the inflammatory process. This drug has also been shown to inhibit the biosynthesis of granulomas and exudates in animals with experimental allergic encephalomyelitis, a condition that mimics multiple sclerosis.Formule :C11H16INODegré de pureté :Min. 95%Masse moléculaire :305.15 g/molTAS-115
CAS :TAS-115 is a monoclonal antibody that binds to the epidermal growth factor receptor (EGFR) and blocks the EGFR signalling pathway. It is used in the treatment of solid tumours, such as lung cancer. TAS-115 has been shown to inhibit Wnt signalling by interfering with the binding of kinase domain of EGFR to its substrate, which leads to inhibition of proliferation and induction of apoptosis in human osteosarcoma cells. In addition, TAS-115 was found to be a potential biomarker for colon cancer.Formule :C27H23FN4O4SDegré de pureté :Min. 95%Masse moléculaire :518.6 g/molNed 19
CAS :Ned 19 is a sophisticated neuromodulation system, derived from advanced optogenetic technology, with a unique capability to precisely control and modulate neuronal activity. This system utilizes a refined approach based on light-sensitive proteins to influence neural circuits with high specificity and temporal precision. This mode of action allows researchers to manipulate targeted neurons with unparalleled accuracy, facilitating the dissection of complex neural networks and behaviors.Formule :C30H31FN4O3Degré de pureté :Min. 95%Masse moléculaire :514.6 g/molMOCAc-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH₂
MOCA-Lys-Pro-Leu-Gly-Leu-A2pr(Dnp)-Ala-Arg-NH₂ is a peptide that binds to the M1 muscarinic receptor. It is a research tool used in pharmacology and cell biology. This peptide has been shown to activate the M1 receptor, which may be due to its ability to inhibit protein kinase C. This peptide can also be used as an inhibitor of the M1 receptor.Formule :C55H80N16O16Degré de pureté :Min. 95%Masse moléculaire :1,221.3 g/mol(Pro-Hyp-Gly)10·xH2O
Pro-Hyp-Gly is a polypeptide that inhibits collagenase, an enzyme that breaks down collagen. Collagenase is an enzyme that breaks down the protein collagen, which forms the connective tissue in humans and other animals. Pro-Hyp-Gly has been found to be a potent inhibitor of collagenase, and can be used for treatment of inflammatory diseases such as arthritis or skin lesions. Pro-Hyp-Gly also inhibits enzymes called proteases, which break down proteins outside of cells. Proteases are important in the breakdown of food particles in the stomach.Formule :C120H172N30O41•20H2ODegré de pureté :Min. 95%Masse moléculaire :3,051.1 g/molSBI-115
CAS :SBI-115 is a synthetic molecule that has been shown to have the potential to detect cancer. It is an organosilicon compound that binds to camp levels and can be used for detection of cancer in cells, tissues, and organs. SBI-115 is also able to bind to unique spatially defined regions of chromosomes in individual cells. This binding causes changes in gene expression, which are detected by a fluorescence microscope. The molecule has been shown to be sensitive and selective for the detection of tumor cells with TP53 mutations (a mutation in the TP53 tumor suppressor gene). SBI-115 has also been shown to inhibit myosin phosphatase activity and regulate tumor cell proliferation through response elements.Formule :C14H13ClN2O4SDegré de pureté :Min. 95%Masse moléculaire :340.78 g/molY-29794 Oxalate
CAS :Y-29794 Oxalate is a synthetic compound classified as a thromboxane receptor antagonist. It is derived from chemical synthesis, primarily targeting the TXA2 receptor pathway. The compound functions by inhibiting the binding and action of thromboxane A2, a potent vasoconstrictor and promoter of platelet aggregation, effectively reducing thromboxane-mediated physiological responses.Formule :C25H36N2O5S2Degré de pureté :Min. 95%Masse moléculaire :508.69 g/molAS2863619
CAS :AS2863619 is a small-molecule drug that activates the phosphoinositide 3-kinase (PI3K) and mitogen activated protein kinase (MAPK) signaling pathways. It has been shown to have a functional effect on inflammatory cytokines, cell function, and hypomethylation of DNA. AS2863619 has also been shown to be able to activate the TGF-β pathway in vitro and in vivo. This compound is selective for certain regulatory kinases, such as PI3K and MAPK, but not others. AS2863619 is also an inhibitor of DNA methyltransferase 1 (DNMT1). As such, it is able to inhibit the expression of genes by preventing methylation of their promoter regions. The activation of these pathways leads to increased proliferation activity.Formule :C16H12N8ODegré de pureté :Min. 95%Masse moléculaire :332.32 g/molNBD-TMA
CAS :NBD-TMA is a potent vitamin-like compound that has been shown to have anticancer properties. It works by inhibiting kinase activity, which is an enzyme that plays a crucial role in cell cycle regulation and apoptosis. NBD-TMA has been found to be effective against various types of human cancer cells, including Chinese hamster ovary (CHO) cells and tumor protein-expressing cells. This compound has also been used as a tool for the development of kinase inhibitors, which are promising anticancer agents. NBD-TMA can be detected in urine samples, making it a potential biomarker for cancer diagnosis and treatment monitoring. Overall, this compound shows great promise as an effective anticancer agent with potential clinical applications.Formule :C11H16IN5O3Degré de pureté :Min. 95%Masse moléculaire :393.18 g/molD-Arginyl-[Hyp3,Thi5,D-Tic7,Oic8]-Bradykinin
D-Arginyl-[Hyp3,Thi5,D-Tic7,Oic8]-Bradykinin is a peptide that is an antagonist of bradykinin. It has been shown to bind to bradykinin receptors and inhibit the effects of bradykinin in both the vascular system and central nervous system. D-Arginyl-[Hyp3,Thi5,D-Tic7,Oic8]-Bradykinin may be used to treat diseases such as asthma or chronic obstructive pulmonary disease (COPD).Formule :C59H89N19O13S•2CH3COOH•H2ODegré de pureté :Min. 95%Masse moléculaire :1,496.66 g/mol[Sar1,Ala8]-Angiotensin II
Angiotensin II is a peptide hormone that is part of the renin-angiotensin system. It is used as an antagonist to study the effects of angiotensin in the cardiovascular system. Angiotensin II has been shown to decrease blood pressure by acting on specific receptors that are found on cells in the walls of blood vessels. These receptors cause constriction of these vessels and the release of aldosterone, which increases sodium retention and decreases potassium excretion. This leads to increased blood volume, which results in decreased blood pressure.Formule :C43H67N13O10•CH3COOH•4H2ODegré de pureté :Min. 95%Masse moléculaire :1,058.18 g/molRIG-1 modulator 1
CAS :RIG-1 modulator 1 is a ligand of the RIG-1 receptor, which is a member of the TLR family. It can activate the transcription factor NF-κB and promote the production of inflammatory cytokines. This compound has been shown to inhibit protein interactions that result in apoptosis.Formule :C14H17N5OS2Degré de pureté :Min. 95%Masse moléculaire :335.45 g/molN1,N2-Dimethyl-N1-((3-(4-((1R,3R)-3-(2-(tetrahydro-2H-pyran-4-yl)ethoxy)cyclobutoxy)phenyl)-1H-pyrazol-4-yl)methyl)ethane-1,2-diamin e dihydrochloride
CAS :(1R,3R)-3-(2-(Tetrahydro-2H-pyran-4-yl)ethoxy)cyclobutanol is a potent and selective activator of the GABAA receptor. It is a beta blocker that inhibits the binding of GABA to the GABA receptor. The potency of (1R,3R)-3-(2-(tetrahydro-2H-pyran-4-yl)ethoxy)cyclobutanol at the GABAA receptor has been shown in rat cortical membranes and calf thymus DNA. (1R,3R)-3-(2-(Tetrahydro-2H-pyran-4-yl)ethoxy)cyclobutanol is a specific ligand for the alpha subunit of GABA receptors, which are ligand gated ion channels that are important for regulating neuronal excitability. The synthesis of (1R,3R)-3Formule :C25H40Cl2N4O3Degré de pureté :Min. 95%Masse moléculaire :515.5 g/molFRETS-25Phe (1 umol) (1umol)
FRETS-25Phe (1umol) (1umol) is a synthetic amino acid that is used as a research tool. It activates the Ligand and Receptor, which are proteins that bind to other proteins. FRETS-25Phe (1 umol) (1umol) binds to the Ion channels, which are protein structures that regulate the flow of ions across cell membranes. The activity of FRETS-25Phe (1 umol) (1umol) on Ion channels has been shown using an antibody, which is a type of protein used in immunology to identify, detect and measure antigens. FRETS-25Phe (1 umol) (1umol) also interacts with Cell Biology and Peptides, which are types of proteins involved in cell growth or division.Degré de pureté :Min. 95%RLN1
The RLN1 gene encodes a protein that is involved in the regulation of cell growth, differentiation, and apoptosis. It interacts with a number of proteins involved in cancer, tumour progression and metastasis. The function of RLN1 is to interact with other proteins, such as p53 and BRCA2, and regulate their activity. The frequency of this gene has been analysed in healthy controls versus patients with cancer. A number of different tissues have been analysed for this gene including testicular tissue from healthy controls versus patients with testicular cancer. There are also data on the expression levels in normal tissue and cancerous tissue from the same individual. This gene has also been shown to be homologous to other genes that are involved in DNA repair and apoptosis.Degré de pureté :Min. 95%Ac-Lys-Val-Pro-Leu-CH2Cl
Ac-Lys-Val-Pro-Leu-CH2Cl is a synthetic peptide, which is a fragment of the neurotensin receptor. It can be used as a research tool in cell biology and pharmacology to study protein interactions with receptors. Ac-Lys-Val-Pro-Leu-CH2Cl can also be used as an antibody or an activator of the neurotensin receptor. This product has a high purity level, and is supplied in powder form.
Degré de pureté :Min. 95%CP-532623
CAS :CP-532623 is a protein inhibitor that blocks the activity of the enzyme cholesterol ester transfer protein (CETP). CP-532623 is a member of the class of inhibitors that are soluble, bioconjugates. It has been shown to inhibit CETP in human cancer cell lines and clinical studies have shown that it lowers blood pressure in humans. CP-532623 is not absorbed when taken orally because it is solubilized and not lipid soluble. This drug has been shown to increase serum levels, which may be due to its inhibition of drug absorption.Formule :C27H27F9N2O3Degré de pureté :Min. 95%Masse moléculaire :598.5 g/molPhe-Met-MCA
Phe-Met-MCA is a peptide that specifically activates the ATP-sensitive potassium (KATP) channels. These channels are important for regulating cellular energy metabolism and membrane potential. Phe-Met-MCA is an inhibitor of protein kinase C (PKC), which regulates the activity of KATP channels by phosphorylation. The peptide is also an inhibitor of other protein kinases, including PKCζ, PKCε, and PKCθ.Degré de pureté :Min. 95%L-a-Phosphatidylcholine - PC30
CAS :L-A-Phosphatidylcholine is a natural product that is extracted from the Chinese herb Salvia miltiorrhizae. It is a phospholipid that has been shown to inhibit the growth of colorectal adenocarcinoma cells in vitro. The mechanism of action for L-A-Phosphatidylcholine is unclear, but it may be due to its ability to inhibit the activity of polymerase chain reaction (PCR) and nitrite ion. L-A-Phosphatidylcholine also inhibits fatty acid uptake and acyl chain synthesis in vitro, as well as hydrogen bond formation with the hydroxyl group and water vapor uptake. L-A-Phosphatidylcholine also has a strong affinity for nitrate ions, which may be related to its anti-inflammatory effects.
Formule :C42H80NO8PDegré de pureté :Min. 95%Masse moléculaire :758.06 g/molFiruglipel
CAS :Firuglipel is a synthetic biocompound, which is derived from advanced organic synthesis processes and designed for biotechnological applications. It functions as an enzyme inhibitor, leveraging its unique ability to interact with specific metabolic pathways. This interaction involves competitive binding to active sites within target enzymes, effectively modulating biochemical reactions.
Formule :C25H26FN3O5Degré de pureté :Min. 95%Masse moléculaire :467.5 g/mol(R)-(+)-Corypalmine
CAS :(R)-(+)-Corypalmine is a chemical compound that belongs to the group of antipsychotic drugs. It has been shown to be an effective treatment for bipolar affective disorder in combination with other drugs. The mechanism of action is not yet known, but it may be due to inhibition of oxidative phosphorylation by mitochondrial complex I. (R)-(+)-Corypalmine has also been shown to have anti-inflammatory and antimicrobial properties. This drug inhibits the growth of bacteria and fungi, such as Staphylococcus aureus, by inhibiting protein synthesis. It also inhibits the production of serotonin from tryptophan and protopine from arginine. Metformin hydrochloride is used for the treatment of type 2 diabetes mellitus because it increases insulin sensitivity and decreases glucose production in the liver.Formule :C20H23NO4Degré de pureté :Min. 95%Masse moléculaire :341.4 g/molAmyloid beta-Protein (Human, 1-40) (Scrambled)
Amyloid beta-Protein (Human, 1-40) (Scrambled) is a peptide that consists of 40 amino acids. It is a fragment of the amyloid precursor protein. Amyloid beta-protein has been found to have many different effects in the body, including receptor binding, ion channel activation and inhibition, and protein interactions. The peptide is also an activator for the high-affinity nicotinic acetylcholine receptor in the brain. This product can be used as a research tool or as an antibody to study amyloid beta protein in cellular biology.Degré de pureté :Min. 95%Mepivacaine hydrochloride
CAS :Produit contrôléInhibitor of sodium channelsFormule :C15H22N2O·HClDegré de pureté :Min. 95%Masse moléculaire :282.81 g/mol(E)-Alprenoxime
CAS :(E)-Alprenoxime is an antibody that binds to the nicotinic acetylcholine receptor. It is a potent agonist at the receptor and can be used as a research tool to study the protein interactions, ion channels, and pharmacology of this receptor. (E)-Alprenoxime has been used in studies on cell biology and immunology. This drug also has potential applications in treating neurodegenerative disorders such as Parkinson's disease and Alzheimer's disease.
Formule :C15H22N2O2Degré de pureté :Min. 95%Masse moléculaire :262.35 g/molMK-0941
CAS :MK-0941 is a potential therapeutic for the treatment of type 2 diabetes. It is a novel, orally active, small molecule that has been shown to reduce blood glucose levels in preclinical models. MK-0941 targets pancreatic and hepatic steatosis by inhibiting the uptake of triglycerides from plasma into these tissues. MK-0941 also increases insulin sensitivity in vitro and in vivo. This drug has been studied as monotherapy at doses of 0.1, 1, or 10 mg/kg and as combination therapy with metformin at doses of 5 or 25 mg/kg in db/db mice and wild-type mice. The study drug was well tolerated up to 10 mg/kg without any adverse effects on body weight or food intake observed. MK-0941 has shown promising results in lowering blood glucose levels and improving insulin sensitivity when administered alone or in combination with metformin at high doses.Formule :C22H28N4O9S2Degré de pureté :Min. 95%Masse moléculaire :556.61 g/mol
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