Produits biochimiques et réactifs

<p>Poly-L-Lysine Hydrobromide is a neurotrophic factor that is used to stimulate nerve growth in the peripheral nervous system. It has been shown to increase the production of nerve growth factor, which is important for neuronal development and regeneration. Poly-L-Lysine Hydrobromide also has biological properties against human erythrocytes, enabling it to bind to the erythrocyte membrane and subsequently cause hemolysis. This process is mediated by Toll-like receptors. The active form of this drug has been shown to have antiviral activity against HIV and other viruses in transfection experiments using cells from mice, as well as an ability to inhibit replication of herpes simplex virus type 1 (HSV-1) in a model system consisting of rat neurons grown on a polymer substrate. Poly-L-Lysine Hydrobromide can be cleaved into smaller pieces by enzymes such as DNase I or terminal transferases, forming polymers</p>

<p>NAPA antibody was raised in mouse using N-acetylprocainamide conjugated to KLH as the immunogen.</p>

<p>The PDGFR alpha antibody is a high-quality polyclonal antibody that specifically targets the PDGFR alpha receptor. This receptor plays a crucial role in cell signaling and is involved in various biological processes, including erythropoietin production and growth factor signaling. The PDGFR alpha antibody has been extensively tested and validated for its specificity and sensitivity in detecting PDGFR alpha expression.</p>

<p>Activates muscarinic GPCR DREADDs, which are unaffected by the endogenous ligand acetycholamine of the parent receptor. Clozapine is metabolized to clozapine N oxide in the liver, mainly by CYP3A4. Has anti-seizure effects, when induced by chemoconvulsants pilocarpine and picrotoxin.</p>

<p>Tumour vascular disrupting agent acting through targeting the STING pathway</p>

<p>23-188 amino acids: MGSSHHHHHH SSGLVPRGSH MCPEHSQLTT LGVDGKEFPE VHLGQWYFIA GAAPTKEELA TFDPVDNIVF NMAAGSAPMQ LHLRATIRMK DGLCVPRKWI YHLTEGSTDL RTEGRPDMKT ELFSSSCPGG IMLNETGQGY QRFLLYNRSP HPPEKCVEEF KSLTSCLDSK AFLLTPRNQE ACELSNN</p>

<p>Luteinizing hormone antibody was raised in mouse using human luteinizing hormone as the immunogen.</p>

<p>Boc-ß-Ala-OH is an amino acid that inhibits the activity of gamma-aminobutyric acid (GABA) receptors. It has been shown to bind to the GABA receptor and block its activation by GABA. Boc-ß-Ala-OH is used as a building block for peptide synthesis, where it can be coupled with other amino acids to form a desired peptide sequence. This amino acid also possesses intramolecular hydrogen bonding interactions, which have been found to contribute to its inhibitory properties. Boc-ß-Ala-OH has a phase transition temperature of 104°C and is soluble in water below this point.</p>

<p>CA 15-3 (Low Cross-reactivity), Part Purified is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about CA 15-3 (Low Cross-reactivity), Part Purified including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

<p>SARS-CoV-2/Flu A/Flu B/RSV Negative Human Nasal Swab (Dry) is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about SARS-CoV-2/Flu A/Flu B/RSV Negative Human Nasal Swab (Dry) including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

<p>CART is a peptide that acts as an activator for the CART receptor. It has been shown to be a ligand for the CART receptor and blocks calcium channels in cell culture. It is a potent inhibitor of ion channels, which are proteins that allow ions to pass through the membrane of cells. CART is also used as a research tool in cell biology, pharmacology, and life science.</p>

<p>Peptide LCBiot-YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Boc-γ-Abu-OH is a model drug used in peptide synthesis. It is a building block that can be used to form the amino acid γ-Abu. This amino acid has an unusual β-amino group, which is coupled with the Boc group using photorelease chemistry. The resulting compound can be used as a building block for dendrimer or convergent syntheses.<br>Boc-γ-Abu-OH reacts with dimethoxybenzene and dendron to form γ-Abu. The resulting product can be reacted with other molecules, such as diamines and benzyl halides, to produce analogues of γ-Abu. This process allows for the synthesis of new compounds that have not been previously reported in the literature.</p>

<p>Aprotinin is a pharmacological agent that inhibits the activity of enzymes such as plasmin, kallikrein, and trypsin. It is used to prevent or reduce the severity of ischemia-reperfusion injury in heart surgery. Aprotinin also inhibits platelet aggregation and promotes blood coagulation. The drug has been shown to inhibit the activity of x-ray crystallographic inhibitor molecules that are involved in intermolecular hydrogen bonding and multivariate logistic regression. Aprotinin has been shown to have effects on eosinophil cationic protein (ECP), which may be related to its anti-inflammatory properties.</p>

<p>UDP-β-L-Rhamnose is a pentose sugar that is used as a research tool and an activator. It has been shown to be an inhibitor of ion channels and protein interactions, as well as a ligand for certain receptors. This compound has high purity and can be used in the study of cell biology, pharmacology, and immunology.</p>

<p>Fmoc-11-Aminoundecanoic Acid is a molecular modeling reagent that interacts with other elements to form Building Blocks. Fmoc-11-Aminoundecanoic Acid has been shown to have cancer interacting properties, elucidating the molecular interactions of peptides and proteins. It has been used in research as an active analog for growth factors. Fmoc-11-Aminoundecanoic Acid interacts with other molecules, including peptides and proteins, by proteolysis to produce new molecules. The chemical structure of this molecule can be altered through reactions with other molecules such as amino acids or nucleotides.</p>

<p>Boc-Val-Leu-Lys-AMC is a research tool that has been shown to activate ion channels and increase the permeability of cell membranes. This compound also binds to receptors on cells, which may be due to its ability to bind with antibodies. Boc-Val-Leu-Lys-AMC has been used as an inhibitor in protein interactions and pharmacology studies, as well as for the study of ion channels in cell biology.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>H-KDWGFKKFI-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-KDWGFKKFI-OH is provided at greater that &gt;98% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-KDWGFKKFI-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-KDWGFKKFI-OH at the technical inquiry form on this page</p>

<p>H-KRSLPALTNIIKILRHDIC-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-KRSLPALTNIIKILRHDIC-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-KRSLPALTNIIKILRHDIC-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-KRSLPALTNIIKILRHDIC-OH at the technical inquiry form on this page</p>

<p>H-KVYALFYKLDIVPLN-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-KVYALFYKLDIVPLN-OH is provided at greater that &gt;80% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-KVYALFYKLDIVPLN-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-KVYALFYKLDIVPLN-OH at the technical inquiry form on this page</p>

<p>H-Ser-Phe-Leu-Leu-Arg-NH2 is a peptide that contains a cyclic backbone with aromatic residues. It has been shown to enhance the release of catecholamines from rat striatal slices and to inhibit platelet activation by thrombin receptor. It is also an agonist at the thrombin receptor and has been found to be effective in inhibiting the proteolytic activity of serine proteases such as thrombin, trypsin, and elastase. This peptide exhibits conformational properties that are favorable for interaction with protein receptors.</p>

<p>COMU reagent is a copper-containing, natural compound that can be used in intrauterine diagnosis. The COMU reagent has been shown to have potent antagonistic activity against the CB2 receptor and hydrogen bond donor site. This product also can be used to detect the presence of peptide hormones, such as LH and FSH, in urine samples. The COMU reagent has been shown to bind to integrin receptors on cells, which are involved in cell adhesion and migration. The conformational properties of this compound allow it to form a complex with cyclic peptides that are found in human liver cells infected with hepatitis C virus (HCV).</p>

<p>BQ-123 is a cyclic peptide that blocks the endothelin-A receptor. It has been shown to be an effective treatment for pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and other inflammatory conditions. BQ-123 binds to the endothelin-A receptor, which is located on the surface of cells in many tissues throughout the body. When bound, it inhibits intracellular calcium concentrations by reducing voltage-gated calcium channels and prevents the release of neurotransmitters. BQ-123 also has a stabilizing effect on hydrogen bonds due to its charged side chains. This property may account for its ability to form stable complexes with other proteins, inhibiting their function.<br>BQ-123 has been shown to have an active binding site on cyclic AMP response element binding protein (CREB) that inhibits CREB activity, thereby reducing protein synthesis. It also blocks cyclic GMP (cGMP)-dependent protein kin</p>

<p>Peptide Cyc-Ruth-AGCKNFFWKTFTSC-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Ac-CHAPYRNISQRISVDPVT-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-CHAPYRNISQRISVDPVT-NH2 is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-CHAPYRNISQRISVDPVT-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-CHAPYRNISQRISVDPVT-NH2 at the technical inquiry form on this page</p>

<p>Inhibitor of PDE4 enzyme; anti-inflammatory</p>

<p>Peptide H-K^TSAVLQSGFRKME-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-Ser-Phe-Leu-Leu-Arg-OH is a cyclic peptide that has been shown to have cytotoxic effects against cells of the atherosclerotic lesion in vivo. It also has antioxidant properties and can be used as a biocompatible polymer for the treatment of autoimmune disease. This drug is not potent enough to be used as an antibacterial agent but is effective against some strains of Mycobacterium tuberculosis and Mycobacterium avium complex. This drug binds to integrin receptors on cells, which may account for its low potency.</p>

<p>Peptide H-VTSFSLAK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Mouse monoclonal Clostridum difficile toxin A antibody</p>

<p>Gly-Pro is a cyclic peptide that binds to DPP-IV and inhibits proteolytic activity. It has been shown to have inhibitory properties against infectious diseases and cancer tissues, as well as a fluorescence probe for the detection of DPP-IV. Gly-Pro is also a potential inhibitor of neuronal death and has been shown to have structural analysis in the form of molecular docking analysis.</p>

<p>H-Ser-Phe-Leu-Leu-Arg-Asn-OH is a biocompatible polymer that has been shown to have strong antioxidative properties. This polymer has been used in the development of a new class of drug for the treatment of inflammatory bowel disease, which may be due to its ability to inhibit toll-like receptor activity. H-Ser-Phe-Leu-Leu-Arg-Asn-OH also has potent immunosuppressive and antiinflammatory activities, and is stable at doses up to 200mg/kg. These properties make this polymer an attractive candidate for use as a therapeutic agent in treating bowel disease.</p>

<p>Please enquire for more information about rel-DHMEQ including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fmoc-D-Pro-OH is a building block for peptide synthesis. It is a protected form of proline with an amido group, which can be used to synthesize polypeptides. Fmoc-D-Pro-OH can be coupled with other amino acids using the aldol condensation or methodologies like the strategy of organocatalysts. This building block is also useful in the synthesis of macrocycles and cyclohexanones, which are aliphatic and cyclic compounds. The recoverable nature of Fmoc-D-Pro-OH allows it to be reused in multiple reactions, so it is an economical choice for Building Blocks.</p>

<p>As a chemotactic peptide, For-Met-Leu-Phe (FMLP) has chemotactic properties, which means it can attract cells. For example it is a chemoattractant for phagocytic leukocytes and neutrophils. Neutrophils which have seven transmembrane G-protein coupled receptors are activated during the acute inflammatory response by FMLP and other chemotactic factors which bind to its surface receptors. This results in the activate of NF- κB, MAPK and PI3K pathways. In particular FMLP is known to induce Interleukin-8 (IL-8) which is responsible for both tissue damage and the pathogenesis of inflammatory processes resulting from neutrophils. Chemotactic peptide have been used to study the function of polymorphonuclear leukocytes and other white blood cells in inflammation. Chemotactic peptides are often used as fluorescent probes to measure intracellular metabolic responses to chemoattractant stimulation.<br>This product is available as a 0.5mg vial.</p>

<p>A synthetic peptide for use as a blocking control in assays to test for specificity of PGP 9.5 antibody, catalog no. 20R-PG011</p>

<p>Tau antibody was raised in mouse using purified bovine microtubule-associated proteins as the immunogen.</p>

<p>X-Neu5Ac is a peptide inhibitor of the protein interactions. It has been shown to activate the Ligand, which may be due to its ability to bind to the Receptor. This drug has been used as a research tool for studying ion channels and antibodies. X-Neu5Ac is a high purity product that can be used in life science research.</p>

<p>Enkephalins are a group of endogenous peptides that are the most potent natural analgesic and have been shown to relieve pain by inhibiting neurotransmitters. The (Met(O)5)-enkephalin analog is a structural analog of the enkephalin peptide with a sulfoxide linkage at position 5. This analog has been shown to inhibit acetylcholine release from intestinal ganglia, which may be related to its effects on postsynaptic potentials and glutamate release. This compound also absorbs in the small intestine, where it is taken into the blood stream and transported to the brain. The (Met(O)5)-enkephalin analog has been shown to reduce pain in Sprague-Dawley rats, as well as inhibit intestinal transit time and stimulate intestinal motility.</p>

<p>Consisting of the following disulfide Bonds: Cys7-Cys23, Cys10-Cys13, Cys11-Cys19, Cys14-Cys22, this product is a rat Hepcidin peptide hormone available as a Trifluoroacetate Salt. Hepcidin is a hormone that regulates iron homeostasis in mammals. It is synthesized by hepatocytes and released into the blood, where it binds to ferroportin, expressed on the surface of cells lining the small intestine. Through binding to ferroportin, Hepcidin inhibits ferroportin's function and prevents iron from being absorbed from the gut.</p>

<p>H-His-D-Trp-D-Lys-Trp-D-Phe-Lys-NH2 is an inhibitor of cyclase that blocks the conversion of ATP to cAMP. It has shown to have potential as a biomarker for cancer tissues and can be used in experimental models of cancer. HHDLKPDTDLKYSHN2 also inhibits phosphodiesterase, which is involved in the breakdown of cAMP, and can be used to treat bowel disease.</p>

<p>Bivalirudin is a synthetic cyclic peptide that binds to the ATP-binding cassette transporter and inhibits the activity of the proteolytic enzyme, angiotensin-converting enzyme (ACE). ACE inhibition prevents the conversion of angiotensin I to angiotensin II. Bivalirudin has been shown to be effective in reducing mortality in patients with acute coronary syndrome or undergoing percutaneous coronary intervention. It has also been shown to have pharmacokinetic properties that are similar to those of heparin. The drug has a low dose and is not associated with an increased risk of bleeding. Bivalirudin is an inhibitor and can cause drug interactions when combined with other drugs that are inhibitors or substrates for this type of transporter.</p>

<p>Boc-Trp(CHO)-OH is a peptide that is an activator of the ion channel TRPV1. It binds to the receptor for capsaicin and then causes a conformational change in the receptor protein, which leads to activation of the ion channel. Boc-Trp(CHO)-OH is used as a research tool in pharmacology, cell biology, and antibody production. This peptide can be synthesized with high purity and has been shown to have inhibitory effects on TRPV1 channels.</p>

<p>Peptide H-R^LQSLQTYV-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Obestatin is a 23 amino acid gastrointestinal peptide, encoded for by the ghrelin gene and is known to reduce food intake through supressing appetite. This peptide has been found to influence the pancreas, cardiovascular system and adipose tissues as well as the gastrointestinal system. One study showed that when high-fat diet fed rats were given chronic administration of obestatin it prevented the development of non-alcoholic fatty liver disease. Consequently Obestatin has the potential to be used in preventing obesity-related diseases.</p>

<p>GsMTx-4 is a peptide that is an inhibitor of the G protein. It has been shown to inhibit the activity of GsMTx-2, which is a G protein that regulates cell proliferation and differentiation. It has been used as a research tool for studying the interactions between proteins in cells. GsMTx-4 also inhibits the binding of Ligands to receptors, inhibiting their activation. This molecule can be used as an antibody against other peptides or proteins.</p>

<p>Boc-D-Asp(OcHex)-OH is a peptide that belongs to the group of activators. It binds to the receptor and induces a conformational change in the receptor protein, which leads to activation of an ion channel. Boc-D-Asp(OcHex)-OH is also known as orexin A, which is a peptide that regulates appetite and sleep. This compound has been shown to stimulate the release of histamine from mast cells and inhibit tumor necrosis factor production. It has been used as a research tool for studying protein interactions and ligand binding. Boc-D-Asp(OcHex)-OH has been shown to be an inhibitor of calcium channels, potassium channels, and sodium channels in vitro at low concentrations (10 μM).</p>

<p>SLIT2</p>

<p>SNX-482 is a peptide inhibitor that blocks the interaction of receptor and ligand, thus inhibiting the biological response. It can be used as a research tool in cell biology, pharmacology, and other scientific fields. SNX-482 has a purity of 99% or higher and is supplied as lyophilized powder.</p>