Antibiotiques

Applications Surfactin is a lipopeptide antibiotic and biosurfactant.

Applications N-Carbamoyl Oxcarbazepine is an impurity of Oxcarbazepine (O869250), a metabolite of Eslicarbazepine acetate, (BIA 2-093), a novel central nervous system drug. A keto derivative of Carbamazepine. Used as an anticonvulsant.
References Dam., M., et al.: Epilepsy Res., 3, 70 (1989), Beydoun, A., et al.: Expert Opin. Pharmacother., 3, 59 (2001),

Stability Hygroscopic
Applications A new constituent of bacterial polyhydroxyalkanoic acids.
References Bollard, M., et al.: Toxicol. Appl. Pharmacol., 204, 135 (2005), Slupsky, C., et al.: Anal. Chem., 79, 6995 (2007),

Applications Dicresulene Hydrate is an impurity of Policresulen (P688085), an ideal drug for purulent endometritis and bovine mastitis of the animals.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Xie, R., et al.: Zhejiang Nongye Daxue Xuebao., 24, 259-262 (1998)

Applications 2,3-Bis[(acetyloxy)methyl]-1-oxoquinoxalin-1-ium-4(1H)-olate is an antibiotic.
References Marrero-Ponce, Yovani, et al.: Bioorg. & Med. Chem., 13(8), 2881-2899 (2005)

Applications Streptidine, is a metabolite derivative of Streptomycin (S687500), an antibiotic (antimycobacterial) drug, used for patients suffering from tuberculosis or other infectious diseases.
References Granados, O., et al.: Histology and Histopathology, 20(2), 357 (2005);

Applications Nisin Z Hydrochloride is a peptide antibiotic synthesized by Lactococcus lactis. Nisin Z interacts with lipid II, a lipid component of cell wall, to form pores in the plasma membrane.
References Kuipers, O. P., et al.: J. Biol. Chem. 270, 27299 (1995); Breukink, E., et al.: Science 286, 2361 (1999); Breukink, E., et al.: Biochemistry 36, 6968 (1997)

Impurity Piperacillin EP Impurity B
Stability Hygroscopic, Temperature Sensitive
Applications Piperacilloic Acid (Piperacillin EP Impurity B) is a degradation product of Piperacillin (P479950), a new β-lactam antibiotic.
References Waxman, D.J., et al.: J. Biol. Chem., 255, 3964 (1980), Waley, S.G., et al.: Biochem. J., et al.: 205, 631 (1982),

Applications Telocinobufagin is isolated as a major component from skin secretion of the toad Bufo rubescens. Telocinobufogenin is a novel antibiotic cardiotonic.
References Akizawa, T., et al.: Chem. Pharm. Bull., 42, 754 (1994); Hancock, R., et al.: Antimicrob. Agents Chemother., 43, 1317 (1999); Jing, Y., et al.: J. Cancer Res., 85, 645 (1994); Kamano, Y., et al.: J. Med. Chem., 45, 5440 (2002); Schoner, W., et al.: Eur. J. Biochem., 269, 2440 (2002); Cunha Filho, G., et al.: Toxicon, 45, 777 (2005)

Applications The labelled trans-alcohol metabolite of Loxoprofen (L472900).
References Choo, K.-S. et al.: J. Pharmac. Biomed. Anal., 25, 639 (2001); Cho, H.-Y. et al.: J. Chrom. B Anal. Technol. Biomed Life Sci., 835, 27 (2006); Riendeau, D. et al.: Bioorg. Med. Chem. Lett., 14, 1201 (2004);

Ceftazidime is a broad-spectrum beta-lactam antibiotic that inhibits bacterial growth by inhibiting penicillin-binding proteins (PBPs). It is used to treat many bacteria infections including pneumonia and septicaemia. It has shown to be effective against some treatment-resistant bacteria such as Pseudomonas aeruginosa.