Antibiotiques
Les antibiotiques sont des composés conçus pour détruire ou inhiber la croissance de divers microorganismes, jouant un rôle crucial dans le traitement des infections et la prévention de la propagation des maladies. Cette catégorie offre une gamme diversifiée d'ingrédients actifs spécifiquement destinés à la recherche dans le domaine biochimique. Ces composés sont des outils essentiels pour étudier les mécanismes bactériens, les modèles de résistance et le développement de nouveaux agents thérapeutiques. Les chercheurs peuvent explorer une large variété d'antibiotiques pour comprendre leurs effets, optimiser leur utilisation et développer de nouveaux traitements pour combattre les menaces microbiennes émergentes. La disponibilité d'un spectre aussi large d'antibiotiques soutient la recherche avancée et l'innovation en microbiologie et en sciences pharmaceutiques.
Sous-catégories appartenant à la catégorie "Antibiotiques"
- Antibiotiques macrolides(26 produits)
- Antibiotiques stéroïdiens(31 produits)
- Antibiotiques de type tétracycline(20 produits)
- antibiotiques β-lactames(11 produits)
4100 produits trouvés pour "Antibiotiques"
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Oligomycin A
CAS :<p>Oligomycin A is a macrolide antibiotic, which is isolated from the Streptomyces species of bacteria. Its mode of action involves inhibiting ATP synthase by binding to the F_O subunit of the enzyme complex in the mitochondrial membrane. This binding effectively stops the flow of protons across the membrane, which is critical for ATP generation through oxidative phosphorylation.</p>Formule :C45H74O11Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :791.06 g/mol8-Fluoro erythromycin
CAS :<p>8-Fluoro erythromycin is a synthetic derivative of the macrolide antibiotic erythromycin. It is derived from the fermentation of *Streptomyces erythraeus*, a species known for producing erythromycin, which is chemically modified to include a fluorine atom at the eighth position. This modification enhances its pharmacokinetic properties, improving its stability and bioavailability compared to the parent compound.</p>Formule :C37H66FNO13Degré de pureté :Min. 95%Masse moléculaire :751.92 g/molCeftaroline fosamil acetate
CAS :<p>Cephalosporin antibiotic active against gram-positive bacteria including MRSA</p>Formule :C24H25N8O10PS4Degré de pureté :Min. 98 Area-%Masse moléculaire :744.74 g/molRifamdin
CAS :<p>Rifamdin is an antibiotic, which is a chemical substance derived from the source compound rifampicin. Its mode of action involves the inhibition of bacterial DNA-dependent RNA polymerase, which effectively suppresses bacterial RNA synthesis, leading to cell death. This mechanism primarily targets Mycobacterium tuberculosis, the causative agent of tuberculosis.</p>Formule :C46H64N4O12Degré de pureté :Min. 95%Masse moléculaire :865.02 g/molLydicamycin
CAS :<p>Lydicamycin is an antibacterial compound, which is a polyketide-derived antibiotic produced by the microorganism Streptomyces. This natural compound functions by inhibiting bacterial protein synthesis, effectively interrupting critical cellular processes within susceptible bacteria. The mode of action primarily focuses on binding to the bacterial ribosome, thereby disrupting protein production and inhibiting bacterial growth.</p>Formule :C47H74N4O10Degré de pureté :Min. 95%Masse moléculaire :855.11 g/molN'-Desmethyl azithromycin
CAS :<p>N'-Desmethyl azithromycin is a semi-synthetic derivative antibiotic, which is derived from the chemical modification of azithromycin, a macrolide antibiotic sourced originally from the bacterium *Streptomyces erythreus*. It functions primarily by inhibiting bacterial protein synthesis, binding specifically to the 50S ribosomal subunit, which results in the prevention of transpeptidation and translocation processes during translation. This action effectively halts bacterial growth, rendering it bacteriostatic.</p>Formule :C37H70N2O12Degré de pureté :Min. 95%Masse moléculaire :734.96 g/molClindamycin B hydrochloride
CAS :<p>Clindamycin B hydrochloride is a semi-synthetic antibiotic, which is derived from the parent compound, lincomycin, obtained from the bacterium *Streptomyces lincolnensis*. It exerts its antibacterial effects by binding to the 50S subunit of the bacterial ribosome, inhibiting protein synthesis by preventing peptide bond formation, which is essential for bacterial growth and survival.</p>Formule :C17H31ClN2O5S•HClDegré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :447.42 g/molFosmidomycin sodium
CAS :<p>Fosmidomycin sodium is an antibiotic compound, which is derived from phosphonic acid. It functions as an inhibitor of the enzyme 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR), crucial in the non-mevalonate pathway of isoprenoid biosynthesis. By targeting this enzyme, fosmidomycin sodium disrupts the production of isoprenoids, essential components for the growth and survival of certain bacteria and parasites.</p>Formule :C4H9NNaO5PDegré de pureté :Min. 95%Masse moléculaire :205.08 g/molErythromycin B
CAS :<p>Erythromycin B is a semisynthetic macrolide antibiotic, which is derived from the actinomycete *Saccharopolyspora erythraea*. Its mode of action involves inhibiting bacterial protein synthesis by binding to the 50S ribosomal subunit. This interference with protein synthesis effectively hampers bacterial growth, making it a potent bacteriostatic agent.</p>Formule :C37H67NO12Degré de pureté :90%NmrMasse moléculaire :717.93 g/mol6'-N-Cbz-kanamycin A
CAS :<p>6'-N-Cbz-kanamycin A is a semi-synthetic aminoglycoside antibiotic derivative, specifically a Cbz (carbobenzyloxy) protected form of kanamycin A. It is derived from the natural product kanamycin, which is an antibiotic obtained from the bacterium *Streptomyces kanamyceticus*. The modification involves the introduction of a protective Cbz group at the 6' position, which can improve solubility, stability, or enable further chemical modifications.</p>Formule :C26H42N4O13Degré de pureté :Min. 95%Masse moléculaire :618.63 g/molRolitetracycline
CAS :<p>Rolitetracycline is a semi-synthetic tetracycline antibiotic, which is derived from the natural compound tetracycline. It functions primarily by inhibiting protein synthesis in susceptible bacteria. This is achieved through the binding to the 30S ribosomal subunit, effectively blocking the attachment of aminoacyl-tRNA to the mRNA-ribosome complex, thereby preventing the addition of new amino acids to the nascent peptide chain. As a result, bacterial cell growth is inhibited, leading to bacteriostatic effects.</p>Formule :C27H33N3O8Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :527.57 g/molClindamycin-2,4-diphosphate
CAS :<p>Clindamycin-2,4-diphosphate is a phosphorylated derivative of the antibiotic clindamycin, which is a semi-synthetic lincosamide antibiotic originally derived from Streptomyces lincolnensis. Its mode of action involves the inhibition of bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing peptide chain elongation during translation. This mechanism effectively disrupts protein production in susceptible bacteria, leading to their growth inhibition or death.</p>Formule :C18H35ClN2O11P2SDegré de pureté :Min. 95%Masse moléculaire :584.94 g/molAnhydro erythromycin A
CAS :<p>Anhydro erythromycin A is a semi-synthetic derivative of erythromycin A, which has been shown to be an effective inhibitor of bacterial growth, showing higher selectivity for this inhibition. It is a prodrug that is activated by acid catalysis and can be used as a substitute against methicillin-resistant staphylococcus. Anhydro erythromycin A was developed with the goal of increasing its stability and its potency against methicillin-resistant Staphylococcus aureus, which has been shown to be resistant to erythromycin.</p>Formule :C37H65NO12Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :715.91 g/mol2'-O-Acetylspiramycin I
CAS :<p>2'-O-Acetylspiramycin I is a semi-synthetic derivative of spiramycin, which is a macrolide antibiotic originally sourced from the bacterium *Streptomyces ambofaciens*. The modification involves the acetylation at the 2'-hydroxyl group of spiramycin, enhancing certain pharmacokinetic properties.</p>Formule :C45H76N2O15Degré de pureté :Min. 95%Masse moléculaire :885.09 g/molVirginiamycin - Complex of M1+S1
CAS :<p>Virginiamycin - Complex of M1+S1 is an antibiotic compound, which is derived from the actinobacterium Streptomyces virginiae. It functions through the inhibition of bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby obstructing peptide bond formation and impeding microbial growth. The complex is composed of two major components: Virginiamycin M1 and Virginiamycin S1, which synergistically enhance antimicrobial efficacy.</p>Formule :C71H84N10O17Degré de pureté :Min. 95%Masse moléculaire :1,349.48 g/molCefotiam
CAS :<p>Cefotiam is a broad-spectrum cephalosporin antibiotic, which is a beta-lactam compound derived from the mold Acremonium. It functions by inhibiting bacterial cell wall synthesis, particularly by targeting penicillin-binding proteins, which leads to cell lysis and death in susceptible bacteria. This mechanism of action makes it effective against various Gram-positive and Gram-negative bacteria.</p>Formule :C18H23N9O4S3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :525.62 g/molPhleomycin
CAS :<p>Phleomycin is an antibiotic, which is derived from the bacterium *Streptomyces verticillus*. Its mode of action involves binding to DNA and inducing breaks by generating free radicals in the presence of oxygen and ferrous ions, leading to cell death. Phleomycin is prominently used in molecular biology applications as a selective agent in the generation of stable transfectants. It is particularly effective in selecting for cells that have integrated vectors conferring resistance, such as the Sh ble gene used in yeast, plant, and mammalian cell systems. Due to its potent DNA-cleaving ability, Phleomycin is valuable in studies requiring stringent selection pressure. Researchers commonly utilize it in experiments focusing on genetic modification and cellular resistance development.</p>Formule :C51H75N17O21S2Degré de pureté :Min. 95%Masse moléculaire :1,326.38 g/molPiericidin A
CAS :<p>Piericidin A is a microbial metabolite, specifically a type of polyketide, which is derived from the bacterium of the genus Streptomyces. This compound acts as an electron transport chain inhibitor by specifically binding to the ubiquinone binding site of complex I (NADH:ubiquinone oxidoreductase) in mitochondria. This mode of action results in the disruption of ATP production through oxidative phosphorylation.</p>Formule :C25H37NO4Degré de pureté :Min. 95%Masse moléculaire :415.57 g/molArbekacin sulfate
CAS :<p>Inhibitor of DNA replication; aminoglycoside class</p>Formule :C22H44N6O10·xH2SO4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :650.7 g/mol
