Anticorps d'immunologie

Goat IgG (Fc) is a purified immunoglobulin that has various characteristics and applications in the field of life sciences. This antibody is known for its anti-MERTK activity, which makes it a valuable tool for studying the role of MERTK in different biological processes. Additionally, Goat IgG (Fc) has been shown to interact with colony-stimulating factors, steroids, glucagon, transferrin, and other molecules involved in cellular signaling pathways.

<p>Human IgG2 is an immunoglobulin that plays a crucial role in the immune system. It is involved in various processes, including binding to pathogens and activating immune cells such as macrophages. Human IgG2 has been shown to have a high affinity for mesenchymal stem cells, making it an excellent tool for studying their behavior and functions. In addition, Human IgG2 has been found to modulate the activity of TGF-beta, a key cytokine involved in cell growth and differentiation. This interaction can have significant implications in various biological processes, including wound healing and tissue regeneration. Furthermore, Human IgG2 has been extensively used as a diagnostic agent in Life Sciences research. Its ability to bind specifically to target molecules, such as epidermal growth factor (EGF) or collagen, makes it an invaluable tool for identifying and quantifying these substances in biological samples. Monoclonal antibodies derived from Human IgG2 have also shown promising results as therapeutic agents. For</p>

<p>Purified Bovine IgG (Fc) FITC conjugate</p>

<p>Purified Guinea Pig IgG (Fc)</p>

Acid Phosphatase antibody was raised in rabbit using acid phosphatase [Potato] as the immunogen.

Purified Human IgG Fab protein

Purified Chicken IgG FITC conjugate

Fragment of the signal peptide from endogenous HLA Class I molecules which is also found in viral glycoproteins, for example human Cytomegalovirus (hCMV) protein UL40.  When presented on a cell surface via HLA-E molecules, the HLA-peptide complex binds NKG2A receptors on Natural Killer (NK) cells and some CD8⁺ cytotoxic T cells to reduce their cytotoxic activity. Blocking this interaction is an attractive opportunity for immune checkpoint (IC) approach therapies. This is relevant in both cancer therapies, and viral infections, where endogenous HLA Class I peptide presentation is exploited to escape immune attack.Peptide H-VMAPRTLL^-OH is a heavy-labeled version of PP45242, and is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.

Sheep IgG is a purified immunoglobulin that plays a crucial role in the immune system. It is an endogenous hematopoietic protein that is involved in various physiological processes. Sheep IgG is commonly used in Life Sciences research, particularly in studies involving cell lines such as MCF-7. This monoclonal antibody has shown anti-VEGF (vascular endothelial growth factor) activity, which makes it valuable for studying angiogenesis and tumor growth. Additionally, Sheep IgG has binding affinity to fibrinogen and albumin found in human serum. It can also act as a growth factor and stimulate the production of immunoglobulins in vitro. However, it's worth noting that excessive use of Sheep IgG can be nephrotoxic and cytotoxic, so caution should be exercised when handling this product.

<p>The cyclic pentapeptide cyclo(Arg-Gly-Asp-[D-Phe]-Lys) is a highly potent and selective inhibitor for the alphavβ3 integrin receptor. A related compound, cyclo(Arg-Gly-Asp-[D-Phe]-Val), is a promising anticancer drug candidate- it inhibits angiogenesis and induces apoptosis in vascular cells.Cyclic RGD-containing peptides are selective antagonists of integrins, proteins that play important roles in cell-cell and cell-matrix interactions. In a suitably labelled form, these peptides may serve as useful tools for diagnostic imaging and peptide targeted therapy of some types of cancer.</p>

<p>Elabela/Toddler-32  (ELA-32) has been identified as a new endogenous ligand for the apelin G protein coupled receptor (GPCR). Apelin levels have been shown to be reduced in heart failure and pulmonary arterial hypertension (PAH). ELA-32 delivery could be used to supplement the deficit of apelin. It can be cleaved to shorter forms Elabela/Toddler-21, and Elabela/Toddler-11. Apelin and ELA-32 share almost no sequence homology which is unusual for receptor ligands, it suggests a future for apelin receptor biased agonist design.Exogenous administration of ELA-32 to rats has been shown to compensate for the downregulation of apelin seen in PAH. Further research into the potential of this peptide as an endogenous agonist reducing the severity of PAH could provide vital therapeutics in the future for cardiovascular disease.</p>

Purified Rat IgG (Fab'2) HRP conjugate

<p>Ovalbumin (OVA) is the primary protein in egg-white, and is involved in initiating food allergies and asthma. It is a highly immunogenic protein and can be used for peptide conjugation in the development of antibodies.OVA (250-264) is a class I (Kb)-restricted peptide epitope of OVA. The ovalbumin fragment is presented by the class I MHC molecule, H-2Kb.</p>

Bovine albumin antibody was raised in rabbit using bovine serum albumin as the immunogen.

<p>The cyclic pentapeptide cyclo(-Arg-Gly-Asp-d-Phe-Lys-) is a highly potent and selective inhibitor for the alphavβ3 integrin receptor. A related compound, cyclo(-Arg-Gly-Asp-d-Phe-Val), is a promising anti-cancer drug candidate- it inhibits angiogenesis and induces apoptosis in vascular cells.Cyclic RGD-containing peptides are selective antagonists of integrins, proteins that play important roles in cell-cell and cell-matrix interactions. In a suitably labelled form, these peptides may serve as useful tools for diagnostic imaging and peptide targeted therapy of some types of cancer.</p>

Purified Pig IgG FITC conjugate

Purified Mouse IgG3 FITC conjugate

Aldehyde dehydrogenase antibody was raised in rabbit using aldehyde dehydrogenase isolated from yeast as the immunogen.

<p>Fibrinogen is a large plasma glycoprotein with a complex structure, and one of the most abundant proteins in blood. Fibrinogen is important in fibrin clot formation, haemostasis, and inflammatory responses. Increased plasma fibrinogen indicates a proinflammatory state and is a risk factor for vascular inflammatory diseases including hypertension and atherosclerosis. Fibrinogen cleavage products act as inflammatory activators in the pathophysiology of allergic asthma.The conversion of monomeric fibrinogen into polymeric fibrin is mediated by thrombin, which binds to fibrinogen and catalyses cleavage of fibrinopeptide A (FpA) and fibrinopeptide B (FpB). Fibrinopeptide B is protected from modifications such as carbamylation by pyroglutamination of the N-terminal amino acid.</p>

<p>Ara h 2 is one of the major allergenic proteins from peanut (Arachis hypogaea) which contains approximately 13 potential allergenic proteins.Ara h 2 is a member of the 2S albumins (conglutinins) belonging to the prolamin superfamily which also includes Ara h 6. 2S albumins contain major food allergens from seeds of many mono- and dicotyledon plants and share a common compact structure that renders the proteins highly resistant to proteolysis.In mouse models Ara h 2 and Ara h 6 are the main cause of effector responses such as mast cell degranulation and anaphylaxis. Ara h 2 has a high predictive value for diagnosis of clinical peanut allergy and is also more potent than Ara h 1 or Ara h 3 in histamine release assays and skin prick tests.This peptide represents a tryptic peptide of Ara h 2.</p>