Hétérocycles azotés (N)

1-Aminopyridinium iodide is a reactive compound that can bind to receptors, including the epidermal growth factor receptor. It is also a pyridinium salt and a type of chlorine. The compound has been shown to be effective in inhibiting cancer cell growth and has been used in chemotherapy treatments. 1-Aminopyridinium iodide binds to the glycogen synthase kinase 3 enzyme, which regulates cellular processes such as cell division, and inhibits its activity. This causes the process of glycogen synthesis to stop and leads to cell death by apoptosis. 1-Aminopyridinium iodide is most commonly used in cancer research because of its ability to inhibit tumor growth.

5-Amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-[(trifluoromethyl)sulfinyl]-1H-pyrazole-3-carbonitrile (TCFP), also known as CX-546, is a photosynthetic activity enhancer that inhibits oxidative injury to chloroplasts. TCFP is a pyrazole ring with a sulfinyl group and a chlorine atom. TCFP has been shown to have no genotoxic or carcinogenic potential in vitro and in vivo studies. TCFP is not active against infectious diseases. TCFP can be used as an analytical reagent for the detection of cytochrome P450 activities in human serum.

7-Methylindole is a biochemical substance that is synthesized in the body. It is produced in the liver, and it can be found in the brain, heart, and kidney. 7-Methylindole has been shown to have cancer-fighting properties. 7-Methylindole binds to DNA by methylating nucleic acid bases, which causes a change in the genetic code. This leads to tumor cells being more sensitive to treatment with other substances that inhibit DNA synthesis or repair, such as anthranilate and 5-methoxyindole.

2,4-Dichloro-6-phenyl-1,3,5-triazine is a triazine that has been synthesized and characterized by gel permeation chromatography and powder diffraction analysis. This compound is insoluble in organic solvents due to its high molecular weight. 2,4-Dichloro-6-phenyl-1,3,5-triazine has a number of different applications in the field of polymer science as an acceptor for activated polymers. It can also be used for thermally or photophysically activated polymers. The molecular structure of this compound was determined using x-ray crystallography and molecular modelling techniques.

3-Hydroxy-2-hydroxymethyl-6-methylpyridine is an intermediate in the synthesis of a variety of organic compounds. It can be prepared by the cross-coupling reaction of 3,4-dihydroquinoline with aniline, which is catalyzed by copper (II) chloride. This compound has a chlorine atom and a hydroxyl group that are both trisubstituted with alkyl groups and it can be oxidized to produce different oxidation products. 3-Hydroxy-2-hydroxymethyl-6-methylpyridine also reacts with halides and triflates to form enolates, which are activated for nucleophilic substitution reactions. The molecular ion [M+H]+, which corresponds to the neutral molecule, can be observed by mass spectrometry when this compound is ionized in the gas phase. The chemical formula is C8H5NClO2.

An insecticide synergist; P450-dependent monooxygenase inhibitor

Plant hormone; auxin; inducer of root development; used in plant rooting

2-(3-Hydroxypropyl)benzimidazole is a chloroform extract of the bark of the tree, Pongamia pinnata. It has been shown to have antibacterial and antitumor activity. 2-(3-Hydroxypropyl)benzimidazole has been found to be active against methicillin-resistant Staphylococcus aureus (MRSA), showing strong inhibitory effects on bacterial cell growth in vitro. The mechanism of action may be due to its ability to bind to DNA and RNA, preventing transcription and replication. 2-(3-Hydroxypropyl)benzimidazole also inhibits protein synthesis by binding to ribosomes and interfering with the function of enzymes that are involved in this process such as cytochrome c reductase, glutathione reductase, and 3-ketoacyl coenzyme A thiolase.

2-Cyano-3-trifluoromethylpyridine is a fine chemical that is used as a versatile building block in the synthesis of complex compounds. It can be used as an intermediate in research chemicals, reaction components, and speciality chemicals. 2-Cyano-3-trifluoromethylpyridine is a high quality reagent that can be used for the synthesis of various derivatives. It is also a useful scaffold for the development of new drugs and other chemical compounds.

Metosulam is a triazolopyrimidine herbicide that inhibits the growth of weeds by interfering with plant photosynthesis. Metosulam binds to fatty acids and carbohydrates, which prevents these molecules from binding to the enzyme ATP synthase. This results in a loss of energy production, leading to cell death. Metosulam has been shown to cause chronic cough in mice when given at sublethal doses for long periods of time. The chronic cough was found to be due to an interactive effect between metosulam and polymeric matrix in the lungs that caused inflammation.

2-n-Propylpyridine is a carbonyl compound that can inhibit the growth of bacteria and fungi. It has been shown to have inhibitory activities against Covid-19 pandemic, n-oxide, inflammatory diseases, and polymer film formation. 2-n-Propylpyridine has also been found to be an inhibitor of methicillin resistant Staphylococcus aureus (MRSA). The inhibition activity may be due to its interaction with the bacterial cell membrane and inhibition of the synthesis of prostaglandins.