Building Blocks

Versatile small molecule scaffold

5-(3-Hydroxyphenyl)pentanoic acid (5HPP) is a fatty acid that has been isolated from the leaves of Cardunculus sp. and has shown pharmacological and nutritional properties. 5HPP has been shown to inhibit bacterial growth, which may be due to its ability to bind to bacterial DNA. 5HPP also binds to protein markers, such as methoxyphenol and phenolic, which are associated with antioxidant activity. 5HPP profiles have been determined using liquid chromatography in order to identify the major compounds in this phytochemical.

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Methyl-2-propylpentanoic acid is an organic compound that belongs to the class of primary alcohols with a chemical formula CH3(CH2)5COOH. It is an acidic, fatty acid ester that can be synthesized by methylation of pentanoic acid. 2-Methyl-2-propylpentanoic acid has been used as a preservative in food and cosmetics, but it is also used as an intermediate for pharmaceuticals and other organic compounds. The use of 2-methyl-2-propylpentanoic acid as a solvent has been limited because it is highly reactive and corrosive to metal surfaces. This product can react with other compounds to produce new products, such as hippuric acid or citric acid. One theory about the mechanism of this reaction suggests that the reaction proceeds through a free radical chain mechanism.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Ethyl-2-methylheptanoic acid is a monoester of 2-ethylhexanol. It has a crystalline structure and can be found in the form of spherical particles. 2-Ethyl-2-methylheptanoic acid has been shown to have synergistic effects with other surfactants, such as phosphoric acid solution, to extract organic compounds from various surfaces. The extraction process involves lowering the surface tension by adsorbing at least one molecule of the organic compound on the surface and then extracting it by contacting it with an appropriate solvent. Techniques such as scanning electron microscopy (SEM) are used to study the morphology of these spherical particles.

Versatile small molecule scaffold

Versatile small molecule scaffold

Trans-4-Cyclohexyl-L-proline is an enolate that is used as a pharmaceutical intermediate. It has been shown to be effective in the synthesis of fosinopril sodium, a drug used for the treatment of hypertension and heart failure. Trans-4-Cyclohexyl-L-proline also has shown potential use as an antimicrobial agent. It can act as a nucleophilic agent, reacting with chloride ions to form an alkylating agent. The chlorinated product can undergo hydrolysis by hydrochloric acid to yield c1-4 alkyl chloride and hydrogen chloride.