Building Blocks

6-Amino-5-nitro-1,2-dihydropyrimidin-2-one (6ANPD) is a neutral molecule that can form self-assembled monolayers at the air/water interface. 6ANPD adsorbs to the interface by hydrogen bonding and van der Waals interactions. This molecule has been shown to stabilize the monolayer against electrolytes, which are molecules that disrupt the bonding between molecules in a solution. The self-assembled monolayers formed by 6ANPD are two dimensional in nature and have been shown to be stable for more than three months at room temperature.

2-(1-Methyl-4-oxo-1,4-dihydro-5H-pyrazolo[3,4-d]pyrimidin-5-yl)acetohydrazide is a fine chemical that is a versatile building block in the synthesis of complex compounds. It is also a useful intermediate for the synthesis of pharmaceuticals and agrochemicals. CAS No. 938018-24-7

<p>7-Hydroxyloctanoic acid is a fatty acid that is naturally present in the human body. It is also found in dairy products and some vegetables. 7-Hydroxyoctanoic acid can be converted to isocaproic acid by the enzyme 3-hydroxyacyl coenzyme A dehydrogenase (HAD). HAD deficiency can lead to the accumulation of 7-hydroxyloctanoic acid, which may cause symptoms such as fatigue, dizziness, and mental confusion. The conversion of 7-hydroxyloctanoic acid to isocaproic acid is important for the production of energy from fats, so an HAD deficiency can lead to low levels of energy production.</p>

(2S,5R)-5-Methyl-2-prop-1-en-2-ylcyclohexan-1-one is a natural product that is structurally similar to the antibiotic piperitone. It has significant antifungal activity and was found to have minimal inhibitory concentration values against bacterial enzymes. The compound has been shown to bind to dinucleotide phosphate and inhibit bacterial enzyme catalysis. This inhibition leads to an accumulation of substrates for the enzyme and a decrease in the production of ATP. (2S,5R)-5-Methyl-2-prop-1-en-2-ylcyclohexanone inhibits the growth of Candida albicans and Cryptococcus neoformans strains but not Trichophyton mentagrophytes. This may be due to its ability to bind with high affinity to rat liver microsomes, but not human microsomes. (2S,5R)-5

Aminomethyl)dimethylphenylsilane is a polarizer that has shown growth inhibitory activity against pancreatic carcinoma cells. It has also been found to have pharmacological properties, including anti-cancer and anti-inflammatory effects. Aminomethyl)dimethylphenylsilane is non-selective and non-steroidal, meaning it can inhibit the synthesis of prostaglandins and other eicosanoids. This drug has been shown to be toxic in humans, with side effects such as cardiovascular disorders, alzheimer 's disease, and cancer cell growth.

<p>Applications 2,4-Dichloro-5-nitropyrimidine (cas# 49845-33-2) is a compound useful in organic synthesis.<br></p>

<p>Applications trans-2-Pentenoic Acid has been used in preparation of new nonsteroidal human androgen receptor (hAR) agonists from an hAR antagonist pharmacophore, 2(1H)-piperidino[3,2-g]quinolinone.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhi, L., et al.: Bioorg. Med. Chem. Lett., 9, 1009-1012 (1999)<br></p>

<p>Applications Cyclooctanone is a aliphatic cycle that exhibited inhibitory activity towards aldosterone synthase, a promising therapeutic target for the treatment of cardiovascular diseases related to abnormally high aldosterone level.<br>References Yin, L., et al.: PLoS One., 7, 48048 (2012); Rodriguez, J.D.,e t al.: Chem. Biochem. Engin. Quart., 20, 173 (2006);<br></p>

<p>Applications (1R,2S)-rel-1,2-Cyclopentanedicarboxylic Acid is a Possible inhibitor of prolidase.<br>References Mock, W. et al.; J. Biol. Chem. 265, 19606 (1990)<br></p>

<p>Applications 3-Methoxybenzyl chloride is a chemical reagent used to benzylate sugars (e.g. 2-Deoxy-D-ribose [D252000]) and also used to alkylate amides (e.g. Benzyl acetoacetic amide [B222950]).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cheng, M., et al.: Org. Biomol. Chem., 4, 510 (2006); Martin, O., et al.: J. Org. Chem., 53, 3287 (1988)<br></p>

<p>Applications 4-Pyridinecarboxaldehyde, is an heterocyclic building block used for the synthesis of various pharmaceutical compounds, such as new 1,4-dihydropyridin-4-yl-phenoxyacetohydrazones, having anticonvulsant and anti-inflammatory properties.<br>References Ulloora, Sh., et al.: Ehro. J. Med. Chem., 70, 341 (2013);<br></p>

<p>Applications 2-Methoxy-4-aminobenzoic Acid (cas# 2486-80-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Methoxyacetaldehyde Dimethyl Acetal is a reagent used in balancing oral exposure with Cyp3A4 inhibition in benzimidazole-based IGF-1R inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zimmermann, K., et al.: Bioorg. Med. Chem. Lett., 18, 4075 (2008);<br></p>

<p>Applications 3-Iodobenzonitrile<br></p>

<p>Stability Hygroscopic<br>Applications Aminomalononitrile p-toluenesulfonate is a reagent for diazonamide synthesis via heck endocyclization. It may also have implications for developing IκB Kinase-β inhibitors.<br>References Jeong, S., et al.: J. Org. Chem 63, 8640 (1998); Morwick, T. et al.: J. Med. Chem. 49, 2898<br></p>

<p>Applications cis-2-Hexen-1-ol is used in the invention of a repellent for Oryzaephilus surinamensis.<br>References Xu, W., et al.: Faming Zhuanli Shenqing (2017), CN 107258786 A 20171020<br></p>

<p>Applications Dichloroacetic Acid Methyl Ester is used in the preparation of telechelics and block copolymers through living radical polymerization.<br>References Keul, H., et. al.: Macromol. S., 19, 1 (1971)<br></p>