Building Blocks

<p>Versatile small molecule scaffold</p>

<p>4-Methoxy-2-oxo-1,2-dihydropyridine-3-carboxylic acid is a versatile building block and useful intermediate in organic synthesis. This compound can be used as a reagent or speciality chemical for research purposes. It has been shown to be an effective reactant in the preparation of diverse complex compounds. 4-Methoxy-2-oxo-1,2-dihydropyridine 3 carboxylic acid has also been shown to be a high quality material with applications in specialty chemicals and pharmaceuticals.</p>

<p>Pyridine-2-sulfonamide is a synthetic drug that has been shown to inhibit the growth of cancer cells. It binds to the endothelin-A receptor, which is found in many tissues including the heart, brain, and skin. This binding inhibits the binding of epidermal growth factor to its receptor. Pyridine-2-sulfonamide also inhibits pancreatitis by inhibiting the production of hydrogen ions from hydrochloric acid and reducing inflammation. This drug has been shown to be effective against HIV infection.</p>

<p>6-Chloro-1H-pyrazolo[3,4-b]pyridine (6CPD) is a synthetic compound that acts as a cation channel blocker. 6CPD has been shown to inhibit fatty acid oxidation and cardiac uptake of fatty acids in the heart by blocking the uptake of fatty acids into the mitochondria. 6CPD also inhibits the proton uptake in the mitochondria and reduces oxygen consumption. The compound can be transplacental, which means it crosses the placenta from mother to fetus, which may cause fetal death. 6CPD is an endogenous compound that is involved in death by reducing cell proliferation and inhibiting DNA synthesis.</p>

4-[(1E)-2-(3-Hydroxyphenyl)ethenyl]phenol is a metabolite of estrone sulfate. It is a potent estrogen that can be used in the treatment of prostate cancer, to inhibit the growth of cancer cells. 4-[(1E)-2-(3-Hydroxyphenyl)ethenyl]phenol has been shown to have antiestrogenic activity in breast cancer cell lines and to inhibit the formation of estrogen analogs in vitro. 4-[(1E)-2-(3-Hydroxyphenyl)ethenyl]phenol has been used as an estrogen receptor ligand in transfection experiments with human breast cancer cells, resulting in inhibition of target gene expression. The molecule also inhibits DNA polymerase activity and is believed to form carcinogenic nitrosamines and diazonium ions when subjected to nitrite and hydrogen peroxide. This molecule also exhibits weak antioxidant activity, which may be

1-[(2-Azidoethoxy)sulfonyl]-4-methylbenzene is a molecule that inhibits matrix metalloproteinase, a proteolytic enzyme that degrades extracellular matrix proteins. It has been shown to inhibit the growth of cancer cells in vitro and in vivo, which may be due to its ability to inhibit the production of epidermal growth factor (EGF).

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Putrescine is a polyamine plant growth regulator affecting the synthesis of macromolecules. Promotes adventitious root formation. Precursor of spermidine.</p>

<p>3-Hydroxyoctanoic acid is an activated fatty acid that belongs to the group of short-chain fatty acids. It is a hydroxylated derivative of octanoic acid. 3-Hydroxyoctanoic acid has been shown to have antibiotic-resistant properties in human macrophages, which may be due to its ability to inhibit the enzyme activities of beta-lactamases and penicillinase. 3-Hydroxyoctanoic acid also has a nutrient effect on bacteria, preventing the formation of ester linkages between fatty acids and alkanoic acids. This activity may be due to its effects on energy metabolism in bacteria, which may be caused by its ability to inhibit cyclic lipopeptide synthesis and its effects on the citrate cycle.</p>

<p>3,4-Furandimethanol is an antimicrobial agent that is used to treat skin and soft tissue infections. It belongs to the group of compounds called halogens and has a number of natural sources. The fluorescence properties make it a useful tool for biocatalysis, especially in Friedel-Crafts reactions. 3,4-Furandimethanol can be produced from hydrogen chloride, sulfuric acid, and diphenyl ether. This compound is also acetylated by acetic anhydride to produce 3,4-dihydroxymethylfuran (DHMF). 3,4-Furandimethanol has been shown to react with hydrogen sulfate in a polymerization reaction.</p>

<p>H-Imidazo[1,2-a]pyridin-2-amine is a synthetic compound that has been shown to bind selectively to the catalytic subunit of protein kinase A (PKA). This binding inhibits PKA's ability to phosphorylate proteins, which plays a key role in regulating physiological functions such as cell growth and proliferation. H-Imidazo[1,2-a]pyridin-2-amine has been shown to inhibit tumor growth and symptoms in mouse models by targeting amine receptors. The compound also inhibits the proliferation of cancer cells by signaling through the kinase pathways that regulate mitosis. H-Imidazo[1,2-a]pyridin-2-amine is scalable and can be produced at high yields from inexpensive starting materials.</p>

4-(Chloromethyl)-2-methyl-2H-1,2,3-triazole is a useful intermediate and building block in organic synthesis. It is also used as a reagent for the synthesis of other compounds. 4-(Chloromethyl)-2-methyl-2H-1,2,3-triazole has been reported to be an effective inhibitor of protein tyrosine phosphatase 1B (PTP1B), which is involved in insulin signal transduction. This compound has been shown to inhibit the activity of PTP1B with an IC50 value of 5 μM. 4-(Chloromethyl)-2-methyl-2H-1,2,3-triazole can also be used as an additive in pharmaceutical preparations for its ability to prevent aggregation of proteins.

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Tert-Butyl 1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridine-5-carboxylate is a fine chemical that is a useful scaffold for the synthesis of various organic compounds. It is an intermediate for research chemicals and a reaction component for speciality chemicals. Tert-Butyl 1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridine-5-carboxylate has been used as a reagent in the synthesis of complex compounds. This compound has high purity and can be used as a building block in synthesis of other compounds.

Heterocycle with nitrile functional handle

<p>Versatile small molecule scaffold</p>

<p>4-Chloro-3,5-dimethylbenzoic acid (4CMB) is a building block in organic chemistry. It can be used as a reagent, speciality chemical, and research chemical. 4CMB is used to make an intermediate for the synthesis of other chemicals and it can also be used as a reaction component in more complex reactions. CAS No. 90649-78-8</p>