Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Amino-4-methylthiophene-3-carbonitrile is a cyclic molecule that has been shown to be reactive with a number of nucleophiles. 2-Amino-4-methylthiophene-3-carbonitrile is an intermediate in the preparation of other organic compounds and has been used to synthesize polymers. It has also been used for kinetic studies and cyclic voltammetry experiments. This compound was found to react with hydrogen peroxide, which led to the formation of an intermolecular hydrogen bond between the two molecules. This type of reaction has not previously been reported for this class of molecules.

5-Chlorosalicylanilide is a chemical that is used as an analytical reagent. It can be used to determine the concentration of styrene in ethyl esters and has been shown to inhibit the growth of S. aureus and Mycobacterium tuberculosis. 5-Chlorosalicylanilide has also been shown to induce autophagy, which may be an effective treatment for lung cancer cells resistant to chemotherapy drugs. The bulk density of this product is 1.13 g/cm3 at 25°C and 1 atmosphere (1 bar).

Methyl 2-amino-4-methylthiophene-3-carboxylate is a synthetic, biologically active derivative of 2-amino-4-methylthiophene. It is an indirect, noncompetitive antagonist of the 5HT receptor and has shown to be effective in animal models for the treatment of depression. The compound is available in multigrams and can be extracted from its salts with water. Methyl 2-amino-4-methylthiophene-3-carboxylate can also be synthesized.

Versatile small molecule scaffold

5-Amino-1,2-dihydroacenaphthylene is an amide that stabilizes the cellulose derivative by reacting with the amine groups. This compound has shown antitumor activity against human bladder cancer cells in a xenograft model, as well as potential antitumor activity against other cancers. 5-Amino-1,2-dihydroacenaphthylene is a potential anticancer agent that inhibits tumor growth by binding to fatty acids and causing them to form chloride, which leads to apoptosis of tumor cells.

Versatile small molecule scaffold

1,5-Pentylenediphosphonic Acid is a coordination compound that binds to metal ions. It has been shown to have a stable structure and substructures. It inhibits the coordination of hexavalent chromium, which is carcinogenic, by binding to it. 1,5-Pentylenediphosphonic Acid also has an insoluble form that is not soluble in water or ethanol solutions. The solubility of this compound decreases as the temperature increases. 1,5-Pentylenediphosphonic Acid can be used for detecting metal surfaces through crystallography by examining the interaction between the compound and the metal surface. 1,5-Pentylenediphosphonic Acid can also be used for electrochemical impedance spectroscopy as it changes its electrical properties when interacting with metal surfaces.