Réactifs synthétiques

Applications Isotope labelled 1,3-Propanediol, a common organic reagent used in the synthesis of polymers and used in industrial organic chemistry for the synthesis of lubricants, foods, medicines and cosmetics.
References Sun, Y. et al.: Bioproc. Renew. Res. Commod. Bioprod., 289 (2014);

Applications Coprostan-3-ol is a 27-carbon stanol resulted from biohydrogenation of cholesterol in the gut of most higher animals. It is a common biomarker for the presence of human faecal matter in the environment (1,2).This compound is a contaminant of emerging concern (CECs).
References (1) Bull, I. D., et al.: Environ Int. 27, 647 (2002) (2) Bethell, P. H., et al.: J. Archaeol. Sci 21, 619 (1994)

Applications An enantiomer of Atracurium Besylate (A794500). A neuromuscular blocking agent. It could be used in liver transplant patient with safety.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hughes, R., et al.: Br. J. Anaesth., 53, 31 (1981), Basta, S.J., et al.: Anesth. Analog., 61, 723 (1982), Neill, E.A., et al.: Xenobiotica, 12, 203 (1982), Bangsbo, J., et al.: J. Physiol., 422, 539 (1990),

Applications A useful phase transfer catalyst.

Applications Bis(pinacolato)diboron is used as a condensation agent in the preparation poly(arylene)s. Bis(pinacolato)diboron is an organoboranate with potential use as matrix metallo-proteinase (MMP-2) inhibitor.
References Ali, H.A. et al.: Arch. Pharm., 337, 183 (2004); Izumi, A. et al.: Chem. Lett., 7, 728 (2000);

Applications MK 1775 is used in biological studies for the abrogation of G2/M checkpoint through WEE1 inhibition in combination with chemotherapy as a promising therapeutic approach for mesothelioma.
References Indovina, P., et al.: Cancer Bilo. Ther., 15, 380 (2014);

Applications Sodium Hydrosulfite is used in the process of vat dyeing and as a reducing agent in solution.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Baumgarte, U., et al.: Textilveredlung, 2, 896 (1967); Ebel, R., et al.: Chem Lett., 9, 1091 (1977);

Applications rac Albuterol is a β2-adrenoceptor agonist. Bronchodilator; tocolytic. This compound is a contaminant of emerging concern (CECs).
References Miyagawa, N., et al.: Biol. Pharm. Bull., 31, 2260 (2008), Gonzalez-Munoz, C., et al.: Eur. J. Pharmacol., 607, 151 (2009), Kern, C., et al.: J. Med. Chem., 52, 1773 (2009),

Applications m-Toluic acid is used as a reagent in the preparation of hybrid molecules containing oxadiazole and thiadiazole bearing Schiff base moiety as it has antitumor activities.
References Zhang, K., et al.; Bioorg. Med. Chem. Lett., 24, 5154 (2014);

Applications A selective inhibitor of cyclic-GMP phosphodiesterase (PDE V, calmodulin insensitive). Since cGMP mediates the vasorelaxant action of nitric oxide, as well as the natriuretic and diuretic effect of atrial natriuretic factor (ANF) through the activation of PKG (cGMP dependent protein kinase), such inhibitors may display vasodilating, relaxant, and diuretic effects. These compounds may prove useful in treating hypertension and congestive heart failure.
References Burns, F., et al.: Biochem. J., 238, 487 (1992), Lugnier, C., et al.: Am. J. Physiol., 262, H654 (1992),

Applications STANNOUS OCTOATE (cas# 301-10-0) is a useful research chemical.

Applications 5-Methyl-4-nitroimidazole can cause mutations with Klebsiella pneumonia and Salmonella typhimurium.
References Voogd, C.E., et. al.: Mutat. Res. Genet. Tox. Testing, 66, 207 (1979); Kramers, P.G.N.: Mutat. Res. Genet. Tox. Testing, 101, 209(1982)

Applications Used in the synthesis of (4S,5S)-(-)-isocytoxazone.
References Kakeya, H., et al.: J. Antibiot., 51, 1126 (1998), Carter, P., et al.: Bioorg. Med. Chem. Lett., 13, 1237 (2003),

Applications Labelled Vincristine. An antitumor alkaloid isolated from Vinca rosea Linn. An antineoplastic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Burns, J.H., et al.: Anal. Profiles Drug Subs., 1, 463 (1972), Owellen, D., et al.: J. Med. Chem., 15, 894 (1972),

Applications 3-Hydroxytetradecanoic Acid Methyl Ester is used in the preparation of (S)-3-hydroxytetradecanoic acid and synthesis of unnatural analogs of lipid A containing the (S)-acid.
References Gouteux, B., et al.: Environ. Sci. Technol., 39, 1448 (2005), Esteve-Turrillas, F., et al.: J. Agric. Food Chem., 56, 1797 (2008),

Applications Tetrabutylammonium Bromide is used in the synthesis of polymer solar cells. Also used in the synthesis of single component green-light emitting electrochemical cells.
References Yun, H. et al.: Chem. A Eur. J., 19, 13242 (2013); Sun, M. et al.: J. Disp. Tech., 9, 476 (2013);

Applications Synthetic keto-derivative of Petromyzonol (P293500), a bile salt derivative isolated from the sea lamprey (Petromyzon marinus ) ammocoete (larval form). May be used to study the biochemical characteristics of these and other compounds containing the allocholic acid ring nucleus.
References Haslewood, G., et al.: Biochem. J., 114, 179 (1969); Sorensen, P.W., et al.: J. Gen. Physiol., 105, 569 (1995), Krasowski, M., et al.: Mol. Endocrinol., 19, 1720 (2005),

Stability Moisture Sensitive
Applications 4-Nitrophenyl Chloroformate is an ester of chloroformic acid used in the immobilization of enzymes and other biomolecules.
References Scouten, W.H, et al.: Ann. N.Y. Acad. Sci., 750, 391 (1995); Mikulec, L.J. et al.: J. Biomed. Mat. Res., 32, 203 (1996);

Stability Moisture Sensitive
Applications 2-Methylbutyl Chloroformate is an ester of chloroformic acid and is used as an intermediate in the synthetic preparation of pharmaceutical goods and inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Dupuy, W.E., et al.: J. Chem. Soc. Phy. Org. Chem., 1, 74 (1973);