Réactifs synthétiques

Applications Hoveyda-Grubbs Catalyst 1st Generation is a ruthenium-based olefin metathesis catalyst.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kingsbury, J.S. et al.: Journal of the American Chemical Society, 121, 791 (1999);

Applications 4-Methoxyindole is a reactant for alpha-ethyltryptamines as dual dopamine-serotonin releasers.
References Blough, B. E., et al.: Bioorg. Med. Chem. Lett., 24, 4754 (2014)

Impurity Atomoxetine EP Impurity D
Applications m-Methyl Atomoxetine Hydrochloride (Atomoxetine EP Impurity D) is an impurity of Atomoxetine (A791400), a norepinephrine reuptake inhibitor.
References Farid, N.A., et al.: J. Clin. Pharmacol., 25, 296 (1985), Gehlert, D.R., et al.: J. Neurochem., 64, 2792 (1995), Hwamg. et al.: Neurosci. Lett., 265, 151 (1999), Ring, B.J., et al.: Drug Metab. Dispos., 30, 319 (2002),

Applications JNJ 17203212 is a high affinity TRPV1 receptor antagonist.

Applications 3-Phenylpropyne is a useful synthetic intermediate. It is an intermediate used to synthesize carlina oxide. It can also be used to prepare triazole substituted pyrazolopyrimidinamide derivatives via click chemistry as potential inhibitors of the Plasmodium falciparum PfPK7 protein kinase.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Klein, M., et al.: Org. Biomol. Chem., 7, 3421 (2009)

Applications Tin(II) trifluoromethanesulfonate (cas# 62086-04-8) is a useful research chemical.

Applications 3-Pyridinemethanol is a useful synthetic intermediate. It can be used in the synthesis of histone deacetylase inhibitors. It can also be used to prepare (phenyl)(cyanopyrazinyl)urea derivatives as possible kinase-1 (Chk1) inhibitors.
References Suzuki, T., et al.: J. Med. Chem., 42, 3001 (1999); Li, G., et al.: Bioorg. Med. Chem. Lett., 16, 2293 (2006)

Stability Hygroscopic
Applications XL413 is a potent and selective cell division cycle 7 homolog (CDC7) kinase inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Koltun, E., et al.: Bioorg. Med. Chem. Lett., 22, 3727 (2012)

Applications 1-(Formamidomethyl)-1H-benzotriazole is a useful reagent for the synthesis 1-​isocyanomethyl azoles and related compounds.
References Saikachi, H., et al.: Chem. Pharm. Bull., 31, 723 (1983)

Applications 3,5-Dibromobenzaldehyde is a dibrominated benzaldehyde that is a very useful building block for the preparation of a wide range of biologically active compounds such as a antibacterials
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Nielsen, S. et al.: Bioorg. Med, Chem., 12, 3017 (2004); Balderamos, M. et al.: Exp. Biol. Med., 233, 1395 (2008);

Applications Trifluoromethanesulfonic Acid Magnesium Salt is a strong acid that is used as a catalyst for esterification.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Howells, R. D., et al.: Chemical Rev., 77, 69 (1977);

Applications Gold(III) chloride (CAS# 13453-07-1) is a useful research chemical compound.

Applications MNI-caged-L-glutamate, is a new caged neuroactive amino acid, that use 4-methoxy-7-nitroindolinyl- (MNI) group to make caged ligands specific for glutamate receptor sub-types. MNI-caged-L-glutamate, rapidly release glutamate when photolysed.
References Palma-Cerda, F., et al.: Neuropharmacology, 63, 624 (2012); Canepari, M. J. Neuroscience Methods, 112, 29 (2001);

Stability Hygroscopic
Applications Niperoditine is a H2 antagonists used in the treatment intestinal disorders.
References Mannino, S. et al.: Pharmacoepidemiol. Drug Safety, 7, 233 (1998); Miyaji, Y. et al.: Bioanalysis., 4, 263 (2012);