Anneaux à 6 chaînons

Applications 1,3,5-Benzenetriamine could have cosmetic applications. It could be used for colouring hair with nitrile-containing dyes.
References Suenger, G., et al.: PCT Int. Appl. (2005), WO 2005120445 A2

Applications ETHYL 4-NITROBENZOATE (cas# 99-77-4) is a useful research chemical.

Applications 2-(Hydroxyimino)-3-phenylpropanoic acid (cas# 3682-17-5) is a useful research chemical.

Applications 4-(ETHOXYCARBONYL)BENZOIC ACID (cas# 713-57-5) is a useful research chemical.

Applications N-Phenyl-1-napthyl Amine is a chemical reactant used in the preparation of aryl halides and diarylamines. It also forms oligomers used as hole transport for green electrophosphorescence.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yamamoto, T. et al.: Tetrahedron Lett., 39, 2367 (1998); Zhang, S. et al.: Dyes and Pigments., 118, 1 (2015)

Applications Diamino-5-phenylthiazole Hydrobromide is an phenylthiazole derivative used in the preparation of antiallergic and antiinflammatory agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ban, M. et al.: Bioorg. Med. Chem., 6, 1069 (1998);

Applications 4-(2-Amino-ethyl)-benzoic Acid is a useful reagent for the preparation of amino acid derivatives with anticancer activity.
References Kim, S., et al.: PCT Int. Appl. (2020), WO 2020204548 A1

Impurity Zidovudine EP Impurity D; Irbesartan Triphenylmethanol Impurity; Losartan Impurity G
Applications Triphenylmethanol (Zidovudine EP Impurity D) is a triaryl methane derivative as antiproliferative agent.
References Buchel, K., et al.: Arzneim.-Forsch., 22, 1260 (1972), Sawyer, P., et al.: Drugs, 9, 424 (1975),

Applications Triphenylamine (cas# 603-34-9) is a useful research chemical.

Applications benzo[b]fluoren-11-one (cas# 3074-03-1) is a useful research chemical.

Applications Cyclopentyl Phenyl Ketone is used in the preparation of ortho-arylated compounds and phenanthrones by palladium-catalyzed chelation-assisted C-H activation of Cyclopentyl Phenyl Ketone.
References Gandeepan, P., et al.: J. Am. Chem. Soc, 132, 8569 (2010)

Applications N-[4-(-Carboxycyclohexylmethyl)]maleamidic Acid (cas# 72748-87-9) is a compound useful in organic synthesis.

Applications 5,7-Dimethoxy-2-phenylchromen-4-one is potential therapeutic agents, Polymethoxylated Flavones Isolated from Kaempferia Parviflora for cataract prevention through inhibition of matrix metalloproteinase-9 in lens epithelial cells.
References Kosano, H., et al.: Biological & Pharmaceutical Bulletin, 42, 1658-1664 (2019);

Applications (+)-Dibenzoyl-D-Tartaric Acid Monohydrate (cas# 80822-15-7) is a useful research chemical.

Applications 1,1-Bis(4-hydroxyphenyl)-2-phenyl-1-butene (cas# 91221-46-4) is a compound useful in organic synthesis.

Applications 4-(Isocyanatomethyl)benzonitrile is used as reactant/reagent for design and synthesis of nonpeptide inhibitors of hepatocyte growth factor activation.
References Venukadasula, P. K. M., et al.: ACS Med. Chem. Lett., 7, 177-181 (2016);

Applications Methylbenzeneethanol is a chemical reagent used towards the synthesis of ruthenium nanoparticles supported on graphene.
References Gopiraman, M. et al.: J. Phys. Chem. C., 117, 23582 (2013);

Impurity Bicalutamide EP Impurity D
Applications 5-Amino-2-cyanobenzotrifluoride (Bicalutamide EP Impurity D) is used for the preparation of benzene derivatives as non-steroidal androgen receptor modulators.
References Xiao, H.-Y., et al.: Bioorg. Med. Chem. Lett., 20, 4491 (2010),

Applications 4-Hydroxybenzylideneacetone is a reagent in the synthesis of anti-proliferative agents with 2-nitrophenylacetonitrile moieties.
References Zhang, X. et al.: Org. Biomol. Chem., 12, 355 (2014);

Applications Cyclohexyl-1-cyclohexenyl Ketone is used in the preparation of enones by nickel-catalyzed carbonylative Negishi cross-coupling.
References Wang, Q., et al.: Tetrahedron Lett., 49, 2916-2921 (2008)

Applications N-​Ethyl-​p-​toluenesulfonamide is a reagent used in the sulfonamidation of imidazopyridines.
References Gao, Y. et al.: Org. Biomol. Chem., 15, 8102 (2017);

Applications 2-Phenylhydroquinone (cas# 1079-21-6) is a compound useful in organic synthesis.

Applications 4-Benzyloxyphenyl 4-Hydroxyphenyl Sulfone is used in the synthesis of Bis(4-hydroxyphenyl) Sulfone O-β-D-Glucuronide (B447395), which is a compound that is commonly used as a reactant in epoxy reactions. It is also used as a latent thermal catalyst for epoxy resin.
References Fu, J.W., et al.: Adv. Mat. Rsch., 266, 1022 (2011); Li, J.X., et al.: Polymers. Adv. Tech., 23, 803 (2012)

Applications 6-Benzyl-2-thiouracil (cas# 6336-50-1) is a useful research chemical.

Applications 2-(Diphenylmethoxy)-N-ethylamine (cas# 17349-94-9) is a compound useful in organic synthesis.

Applications 2,3-dihydroxypropyl 4-hydroxybenzoate (cas# 93778-15-5) is a useful research chemical.

Applications Mesitoic acid can be used for its antioxidant.
References Thomas, P.S., et.al.: Medicines, 4, 1-7, (2017);

Impurity Ketoprofen EP Impurity I
Applications (3-Benzoylphenyl)acetonitrile (Ketoprofen EP Impurity I) is a Ketoprofen intermediate.
References Allais, A., et al.: Eur. J. Med. Chem., 9, 381 (1974).

Applications 2-(4-((1-(Methoxycarbonyl)-2-oxocyclopentyl)methyl)phenyl)propanoic Acid is a reagent used in the preparation of Loxoprofen Sodium
References Liu, Q., et al.: Faming Zhuanli Shenqing (2016), CN 105218351 A 20160106

Applications Ethyl 4-Phenylacetoacetate is a useful synthetic intermediate. It is used to prepare pyrazolone derivatives as antiprion compounds. It is also used to prepare pyrrolinylaminopyrimidine analogs as inhibitors of AP-1 and NF-κB mediated gene expression.
References Kimata, A., et al.: J. Med. Chem., 50, 5053 (2007); Palanki, M., et al.: Bioorg. Med. Chme. Lett., 12, 2573 (2002)

Applications Pentafluorobenzoic acid (cas# 602-94-8) is a useful research chemical.

Stability Hygroscopic
Applications 4-(2-Aminoethyl)benzene-1,2-diol has been studied for its role in Parkinson's disease.
References Segura-Aguilar, J.: Neural Regeneration Research, 12, 897 (2017)

Applications Methyl 2,3-dichlorobenzoate

Applications Chlorobenzene is a halogenated benzene used in chemical toxicity QSAR research for agricultural pollution.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Fielden, M., et al.: Curr. Opin. Drug Discovery Dev., 9, 84 (2006), Jonker, M., et al.: Carcinogenesis, 30, 1805 (2009), Jennen, D., et al.: Toxicol. Sci., 115, 66 (2010),

Applications 4,4'-Bis(dimethylamino)benzophenone (cas# 90-94-8) is a useful research chemical.

Applications Dicyclohexylmethanol is a useful reagent for the synthetic preparation of cyclohexane derivatives.
References Moos, G., et al.: Angew. Chem. Int., 59, 11977 (2020)

Applications α-Toluenol is used in the synthesis of Cephalosporolide B as a versatile biomimetic synthetic precursor for chemical synthesis of other cephalosporides.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Song, L. et al.: Org. Lett., 15, 5850 (2013);

Applications 4-Amino-3-hydroxybenzoic Acid is disubsituted benzoic acid used in the preparation of various pharmaceutical compounds such as sphingosine kinase inhibitors.
References Kono, K. et al.: J. Antibiot., 53, 759 (2000);

Applications 4-Biphenylcarboxylic acid (cas# 92-92-2) is a useful research chemical.

Stability Hygroscopic
Applications 5-[(3-hydroxyphenyl)methyl]oxolan-2-one (cas# 21618-91-7) is a useful research chemical.

Applications p-Xylene is a colorless organic solvent. It is used in the production of benzoic, isophthalic and tetraphillic acids.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bramucci, M., et al.: Appl. Microbiol. Biotechnol., 58, 255 (2002)

Applications 2-amino-6-hydroxybenzoic acid (cas# 567-62-4) is a useful research chemical.

Applications Diethyltoluenediamine is used in preparation of hydroxyl and amino-modified anti-explosion composite materials.
References Wei, M., et al.: Faming Zhuanli Shenqing, (2021);

Applications Benzensulfonic Acid Monohydrate is used in the synthesis of HER2/EFGR dual inhibitors in the treatment of cancers and displaying potency towards anti-tumor activity.
References Kawakita, Y. et al.: Bioorg. Med. Chem. Lett., 20, 6171 (2012);

Applications Iodosobenzene (cas# 536-80-1) is a useful research chemical.

Applications 3-(4-Hydroxy-3,5-dimethoxyphenyl)propanoic Acid (cas# 14897-78-0) is a useful research chemical.

Applications N-(2,4-Dimethylphenyl)-3-oxobutanamide (cas# 97-36-9) is a useful research chemical.

Applications 2-(2-Cyanophenyl)benzonitrile

Applications N-Alkyl(C12-16)-N-benzyl-N,N-dimethylammonium chloride, tech. (cas# 68424-85-1) is a useful research chemical.

Stability Light Sensitive, Moisture Sensitive
Applications (S)-2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile is used as a reagent in the synthesis of Fluvalinate (F601100) and its related analogs which exhibit insecticidal activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Anderson, R.J., et al.: J. Agr. Food Chem., 33, 508 (1985)

Stability Hygroscopic
Applications Diphenyltin Dichloride belongs to a class of organotin compounds that are commonly used as pesticides, fungicides, and plastic additives. It is an environmental pollutant with potential antitumor activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Khosa, R.L. et al.: Sci. Cult., 35, 637 (1969); Hamasaki, T. et al.: Mutat. Res. Gen. Toxicol. Test., 300, 265 (1993); Peng, J.: Yaox. Xueb., 29, 406 (1994)

Applications P-QUATERPHENYL (cas# 135-70-6) is a useful research chemical.

Applications 3,5-Di-tert-butyl-4-hydroxybenzoic acid hexadecyl ester

Applications Phthalanilic acid is a compound that is useful in the production of fertilizers.
References Liang, S., et al.: Faming Zhuanli Shenqing.,4 (2019)

Applications Benzyltrimethylammonium Hydroxide is a reagent used in the preparation of dithiocabamates.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zaidi, S. et al.: Chem. Biol. Interface., 7, 166 (2017);

Applications 1,4-dibutyl benzene-1,4-dicarboxylate (cas# 1962-75-0) is a useful research chemical.

Applications N-Benzoyl Isothiocyanate (cas# 532-55-8) is a compound useful in organic synthesis.

Applications 2-AMINO-5,6-DIMETHYLBENZOTHIAZOLE (cas# 29927-08-0) is a useful research chemical.

Applications Intermediate in the preparation of Modafinil
References Stark, H., et al.: Eur. J. Med. Chem., 29, 695 (1994), Cass, Q., et al.: J. Pharm. Biomed. Anal., 46, 937 (2008),

Applications 2-(Methylthio)Benzothiazole could be useful for removing pollutants in drinking water.
References Di Marcantonio, C., et al.: Chemosphere, 260, 127630 (2020)

Stability Moisture Sensitive
Applications Eye irritant.
References Bagley, D. M. et al.; Toxicol. In Vitro 13, 505 (1999); Gilleron, L. et al.; Toxicol. In Vitro 11, 641 (1997)

Applications m-Aminophenyl Tosylate is a reactant used in the synthesis of 2-methyl-5-(2,3,4,5,6-pentafluorophenyl)benzothiazole and 4-[(2',3',4',5',6'-pentafluoro-1,1'-biphenyl-3-yl)amino]benzonitrile.
References Lee, D.S., et. al.: RSC Advances, 2, 9179 (2012)

Applications Diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide (cas# 75980-60-8) is a useful research chemical.

Applications 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one (cas# 569646-79-3) is a useful research chemical.

Stability Hygroscopic
Applications Trimethyl Orthobenzoate is a reagent used in the synthesis of quinazolines. Also used in the prepaaration of nintedanib (N478290), used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.
References Bhat, S. et al.: J. Hetero. Chem., 52, 1253 (2015); Xu, R. et al.: J. Labelled. Comp. Radiopharm., 58, 308 (2015);

Applications Aminophenyltrimethoxysilane is a useful intermediate for the preparation of aromatic silanes as high thermal stability coupling agents.
References Pan, Y., et al.: Adv. Mat. Res., 690, 1483 (2013)

Applications Benzo[a]pyrene-1,6-quinone is a metabolite of Benzopyrene (B205800) and is able to induce epidermal growth factor receptor (EGFR) cell signaling in human mammary epithelial cells. Also highly mutagenic and carcinogenic.
References Rodriguez-Fragoso, L., et al.: Toxicol. Appl. Pharm., 235, 321 (2009); Sen, S., et al.: Chem. Res. Toxicol., 25, 2117 (2012)

Applications 3-(Benzyloxy)-2,2-dimethyl-1-propanol is an protected intermediate of NPG Glycol (N897000), is used in the synthesis of tetraphenylporphyrins.
References Lindsey, J. et al.: J. Org. Chem., 52, 827 (1987); Evans, D. et al.: J. Am. Chem. Soc., 121, 7540 (1999);

Applications Dibenzofuran is a reagent in Friedel-Crafts acylation.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Albrecht, W. L., et al.: J. Med. Chem., 20, 364 (1977);

Applications Benzylamine has been used as a reactant in the preparation of diacetylated benzylamide which has shown to induce a G1/G0 arrest in tumor cells and cytotoxicity against human ovarian cancer cells.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Siewert, B., et. al.: Bioorg. Med. Chem., 22, 594 (2014)

Applications (5-Amino-2-butyl-3-benzofuranyl)[4-[3-(dibutylamino)propoxy]phenyl]methanone is an intermediate used in the synthesis of dronedarone hydrochloride (I), a class III antiarrhythmia drug for the prevention of cardiac arrhythmias such as atrial fibrillation.
References Mali, A. C., et al.: Org. Proc. Res. Dev., 17, 863 (2013)

Applications N-(2,6-Diisopropylphenylcarbamoylmethyl)iminodiacetic Acid (cas# 65717-97-7) is a compound useful in organic synthesis.

Stability Moisture Sensitive
Applications Butyl Benzenesulfonate is an aryl-sulfonate genotoxic impurity found in trace levels in drug substances.
References An, J. et al.: J. Pharmac. Biomed. Anal., 48, 1006 (2008);

Applications A potential antiparasitic agent.

Applications A metabolite of aldehydes.
References Shiobara, Y., et al.: Xenobiotica, 9, 157 (1979),

Applications Cyclohexanemethanol is a chemicl reagent used in the synthesis of potent inhibitors of cyclin-dependent kinases 1 & 2.
References Hardcastle, I. et al.: J. med. Chem., 47, 15, 3710 (2004); Sayle, K. et al.: Bioorg. Med. Chrm. Lett., 13, 3079 (2003);

Applications 2,4-Dihydroxybenzoic acid is a useful synthetic intermediate. An organic building block for plastics and rubber products.
References Gautam, R., et al.: Cryst. Growth Des., 18, 1501 (2018); Shvedene, N. V., et al.: J. Anal. Chem., 72, 95 (2017);

Applications 3-Carboxyphenylboronic Acid is used in phenylboronic acid-decorated gelatin nanoparticles for enhanced tumor targeting and penetration.
References Wang, X., et al.: Nanotechnology, 27, 385101 (2016); Wang, X., et al.: Eur. J. Pharm. Biopharm., 113, 168 (2017)

Applications 4-(diethylamino)benzophenone (cas# 18127-87-2) is a useful research chemical.

Applications 1-Phenyl-2-butanamine (cas# 30543-88-5) is a useful research chemical.

Applications 3-Cyclohexenylcarboxylic Acid has been found to be an oxidizable, nongrowth substrate and induces the metabolism of cyclohexanecarboxylic acid and benzoic acid in a strain of Pseudomonas putida. 3-Cyclohexenylcarboxylic Acid has been used as food for cultures of Streptomyces sp.  KCTC 11604BP fkbO deletion mutant to make 32-dehydroxy-FK506, a FK506 analogue containing a non-natural starter unit.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Blakley, E.R., Papish, B.: Can. J. Microbiol., 28, 1324 (1982); Ban, Y.H., et. al.: Mol. bioSystems, 9, 944 (2013)

M02724 - 3-Indolyl-b-D-glucuronide Cyclohexylammonium salt

Applications 4-((4-(Allyloxy)phenyl)sulfonyl)phenol is an additive to enhance the flame-retardation of unsaturated polyester resin (FR-UPR).
References Dai, K., et. al.: Ind. Eng. Chem. Res., 51, 15918 (2012)

Applications 2-Hydroxyphenylacetic Acid (cas# 614-75-5) is a compound useful in organic synthesis.

Applications 5-phenylbenzene-1,3-diol (cas# 7028-41-3) is a useful research chemical.

Applications 2-[Methyl(phenylmethyl)amino]ethanol is used in the preparation of dihydropyrimidinones as sodium iodide symporter inhibitors used to regulate the accumulation of iodide in the thyroid gland. Also used in the synthesis of new class of pseudopeptides as potential inhibitors of β-sheet aggregation.
References Lacotte, P. et al.: ChemMedChem, 8, 104 (2013); Klein, J. et al.: Org. Lett., 14, 330 (2012);