Anneaux à 6 chaînons

Applications Methylcyclohexane is used as an organic solvent and is highly flammable.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bryce-Smith, D et al.: Org. Synth. 67, 113 (1967); Lin, B. et al.: Energy Fuel., 32, 3883 (2018);

Applications A benzoic acid derivative used in photolysis reactions and biomaterial studies.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wetzels, G.M. et al.: Biomaterials., 20, 1879 (1999); Mao, C. et al.: Adv. Coll. Int. Sci., 110, 5 (2004);

Applications 2-Ethoxybenzoic Acid is a component of dental cement. Low concentrations of 2-Ethoxybenzoic Acid in combination with Eugenol (E938640), gives a stabilizing effect to liposomes to lower damages to cells.
References Fujisawa, S., et al.: J. Dent. Res., 82, 43(2003); Brauer, G.M., et al.: J. Dent. Res., 62, 366 (1983); Brauer, G.M., et al.: J. Dent. Res., 63, 137 (1984); Fujisawa, S., et al.: J. Biomed. Mater. Res., 21, 89 (1987)

Applications 4-Benzyloxyphenyl 4-Hydroxyphenyl Sulfone is used in the synthesis of Bis(4-hydroxyphenyl) Sulfone O-β-D-Glucuronide (B447395), which is a compound that is commonly used as a reactant in epoxy reactions. It is also used as a latent thermal catalyst for epoxy resin.
References Fu, J.W., et al.: Adv. Mat. Rsch., 266, 1022 (2011); Li, J.X., et al.: Polymers. Adv. Tech., 23, 803 (2012)

Applications Diethyltoluenediamine is used in preparation of hydroxyl and amino-modified anti-explosion composite materials.
References Wei, M., et al.: Faming Zhuanli Shenqing, (2021);

Applications 5-[(4-Fluorobenzylidene]-2,4-thiazolidinedione (cas# 262601-87-6) is a compound useful in organic synthesis.

Stability Moisture Sensitive
Applications A versatile phosphitylating agent for the phosphorylation of hydroxy amino acids and the preparation of protected phosphopeptides.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Liskamp, R.M.J., et al.: Recl. Trav. Chim. Pays-Bas, 109, 27 (1990)

Applications Ethyl 4-Phenylacetoacetate is a useful synthetic intermediate. It is used to prepare pyrazolone derivatives as antiprion compounds. It is also used to prepare pyrrolinylaminopyrimidine analogs as inhibitors of AP-1 and NF-κB mediated gene expression.
References Kimata, A., et al.: J. Med. Chem., 50, 5053 (2007); Palanki, M., et al.: Bioorg. Med. Chme. Lett., 12, 2573 (2002)

Applications Pentafluorobenzoic acid (cas# 602-94-8) is a useful research chemical.

Applications 3-phenylbutan-2-amine (cas# 21906-17-2) is a useful research chemical.

Applications 4,4'-Bis(dimethylamino)benzophenone (cas# 90-94-8) is a useful research chemical.

Applications 4-Amino-3-hydroxybenzoic Acid is disubsituted benzoic acid used in the preparation of various pharmaceutical compounds such as sphingosine kinase inhibitors.
References Kono, K. et al.: J. Antibiot., 53, 759 (2000);

Applications 2,4-Xylenesulfonic Acid, is used for the preparation of 2,4,5,6-Tetrachloro-m-xylene (T291555). It is also an intermediate for the synthesis of Diphenylbismuth arenesulfonates.
References Sharutin, V. V., et al.: Russian J. Gen. Chem., 70, 687 (2000);

Applications 4-Biphenylcarboxylic acid (cas# 92-92-2) is a useful research chemical.

Applications N-Undecylbenzenesulfonic Acid is an anionic surfactant.
References Mottaleb, M. A.: Anal. Sci., 15, 1137 (1999), Kolb, M., et al.: LaborPraxis, 22, 56 (1998); Ferrer D., et al.: Tenside, Surfact., Det., 34, 278 (1997)

Applications A metabolite of benzene.
References Aoyama, K., et al.: Toxicol. Appl. Pharmacol., 85, 92 (1986), Sutter, T., et al.: J. Biol. Chem., 269, 1309 (1994), Farris, G., et al.: Toxicology, 118, 137 (1997), Jason, J., et al.: J. Immunol. Methods, 207, 13 (1997), Lee, M., et al.: Immunology, 106, 496 (2002),

Applications 2-Hydroxybenzeneethanol can be used to synthesize cyclic products and organoaluminim oligomers. Inelastic electron tunnelling spectra of 2-hydroxyphenethyl alcohol adsorbed on thin-film aluminium and magnesium oxide has been investigated.
References Ziemkowska, W., et al.: Main Group Met. Chem., 21, 105, (1998); Brown, N., et al., Spectrochim. Acta A, 48, 939 (1992)

Applications 6-Benzyl-2-thiouracil (cas# 6336-50-1) is a useful research chemical.

Applications N-Alkyl(C12-16)-N-benzyl-N,N-dimethylammonium chloride, tech. (cas# 68424-85-1) is a useful research chemical.

Applications Used in the preparation of ibuprofen derivatives for their anti-inflammatory activity. Also used in nucleation inhibitors in Dutch resolution of diastereomers.
References Leeman, M. et al.: Angew. Chem. Int. Ed., 47, 1287 (2008); Eur. J. Med. Chem., 45, 3564 (2010);

Stability Hygroscopic
Applications Benzyltrimethylammonium chloride (cas# 56-93-9) is a useful research chemical.

Applications An antimicrobial agent used in cosmetic products.
References Gilliland, D., et al.: J. Appl. Bacteriol., 72, 258 (1992), Routledge, E., et al.: Toxicol. Appl. Pharmacol., 153, 12 (1998), Miller, C., et al.: J. Biol. Chem., 272, 32824 (1997), Nakagawa, Y., et al.: Biochem. Pharmacol., 55, 1907 (1998),

Applications trans-4-Phenyl-3-buten-2-one is used in various synthetic preparations.
References Shao, Y.D., et al.: Euro. J. Org. Chem., 2012, 1590 (2012);

Applications A useful intermediate in the synthesis of 1-substituted adenines.
References Laufer, S., et al.: J. Med. Chem., 48, 710 (2005), Lambertucci, C., et al.: Bioorg. Med. Chem., 17, 2812 (2009),

Stability Moisture Sensitive
Applications Tris(2,4-di-tert-butylphenyl)phosphate is used as a processing stabilizer for polymers.
References Thilen, M., et al.: J. Appl. Polym. Sci., 76, 938 (2000); Pfaendner, R., et al.: Polym. Degrad. Stab., 91, 2249 (2006);

Applications α-Isopropylbenzylamine Hydrochloride is used in the synthetic preparation of arylalkylamines by addition of Grignard reagents to phosphorylaldimines.
References Zwierzak, A., Napieraj, A.: Synthesis, 6, 930 (1999)

Applications 1,4-dibutyl benzene-1,4-dicarboxylate (cas# 1962-75-0) is a useful research chemical.

Applications N-​Ethyl-​p-​toluenesulfonamide is a reagent used in the sulfonamidation of imidazopyridines.
References Gao, Y. et al.: Org. Biomol. Chem., 15, 8102 (2017);

Applications 5-Amino-2-chlorobenzotrifluoride is a compound useful in organic synthesis. It also performs a radioprotective activity against ionizing radiations.
References Blickenstaff, R. T., et al.: J. Pharm. Sci., 83, 219 (1994); Kumari, P., et al.: Org. Biomol. Chem., 16, 2049 (2018)

Applications Tris(3,5-di-tert-butyl-4-hydroxybenzyl) Isocyanurate is used an as antioxidant-stabilizer in polyolefin films intended for packaging nonfatty food as well as an antioxidant in propylene copolymers.
References Son, P.N.: Poly, Degrad. Stab., 2, 295 (1980); Maciejewska, H. et al.: Polimery, 27, 482 (1982); United States Food and Drug Administration: Fed. Reg., 53, 49550 (1988);

Applications Benzyl Methyl Carbonate is used in designing of inhibitors for serine and thiol proteases.

Applications Monobenzyl Terephthalate is a reactant in the preparation of benzoyl-glucopyranosyl ureas as glycogen phosphorylase inhibitors and potential antidiabetic agents M onobenzyl Terephthalate is also an intermediate formed in the synthesis of Cyclotris(1,4-butylene Terephthalate) (C988975), a cyclic trimer of poly(butylene terephthalate), a thermoplastic engineering polymer.
References Nagy, V., et. al.: Bioorg. Med. Chem., 20, 1801 (2012); East, G.C. et al.: Polymer, 23, 323 (1982)

Applications 2-(Methylthio)Benzothiazole could be useful for removing pollutants in drinking water.
References Di Marcantonio, C., et al.: Chemosphere, 260, 127630 (2020)

Applications 1-[4-(2-hydroxypropan-2-yl)phenyl]ethan-1-one (cas# 54549-72-3) is a useful research chemical.

Applications m-Aminophenyl Tosylate is a reactant used in the synthesis of 2-methyl-5-(2,3,4,5,6-pentafluorophenyl)benzothiazole and 4-[(2',3',4',5',6'-pentafluoro-1,1'-biphenyl-3-yl)amino]benzonitrile.
References Lee, D.S., et. al.: RSC Advances, 2, 9179 (2012)

Applications 4-(3-ethoxy-4-hydroxyphenyl)butan-2-one (cas# 569646-79-3) is a useful research chemical.

Stability Hygroscopic
Applications Trimethyl Orthobenzoate is a reagent used in the synthesis of quinazolines. Also used in the prepaaration of nintedanib (N478290), used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy.
References Bhat, S. et al.: J. Hetero. Chem., 52, 1253 (2015); Xu, R. et al.: J. Labelled. Comp. Radiopharm., 58, 308 (2015);

Impurity Bicalutamide EP Impurity D
Applications 5-Amino-2-cyanobenzotrifluoride (Bicalutamide EP Impurity D) is used for the preparation of benzene derivatives as non-steroidal androgen receptor modulators.
References Xiao, H.-Y., et al.: Bioorg. Med. Chem. Lett., 20, 4491 (2010),

Applications Bis(4-hydroxy-3,5-dimethylphenyl) Sulfone (cas# 13288-70-5) is a useful research chemical.

Applications 2,6-Dimethylcyclohexanol (cas# 5337-72-4) is a useful research chemical.

Stability Volatile
Applications Cyclohexane is a cycloalkane and used to prepare precursors of nylon such as Adipic Acid (A291590) and Caprolactam (C175665).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kalinova, Jana P., et al.: Food Chem., 157, 380-384 (2014); Kim, Y. et al.: Ind. Eng. Chem. Res., 51, 15801 (2012); Nehlsen, J., et al.: Ind. Eng. Chem. Res. 45, 518 (2006)

Applications 4-(3-Aminophenyl)-3-morpholinone is an intermediate during the preparation of imidazothiazoles as protein kinase inhibitors for treating cancers.
References Bamaung, N., et al.: PCT Int. Appl. (2009), WO 2009070516 A1 20090604.

Applications Methyl 2-Bromomethylbenzoate is a reactant in the preparation of Methyl 2-((4-(2-(2-methylphenoxy)acetyl)piperazin-1-yl)methyl)benzoate with neuroprotective activity.
References Zhong, Y., et. al.: Chin. J. Struct. Chem., 33, 1096 (2014)

Applications 2,4-Dioxo-4-phenylbutanoic acid

Applications 4-((4-(Allyloxy)phenyl)sulfonyl)phenol is an additive to enhance the flame-retardation of unsaturated polyester resin (FR-UPR).
References Dai, K., et. al.: Ind. Eng. Chem. Res., 51, 15918 (2012)

Applications 2-Hydroxyphenylacetic Acid (cas# 614-75-5) is a compound useful in organic synthesis.

Applications Triphenylsilanethiol is a useful organic building block used for carboxyl activation via silylthioesterification, and in the preparation of synthesis of tetraphenylporphyrinate manganese(III) siloxides.
References Lamar, A. A.; et al.: Tetrahedron Lett., 56, 6034 (2015); Meininger, D. J.; et al.: J. Coord. Chem., 69, 1970 (2016).

Applications 2-Aminobenzyl alcohol (cas# 5344-90-1) is a useful research chemical.

Applications m-Xylene is an organic solvent used in histology. It is also used after tissue sections have been stained to make them hydrophobic so a coverslip may be applied with a resin in solvent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Watanabe, M., et al.: Stain Technol., 50, 239 (1975); Wishe, H., et al.: Anat. Rec., 197, 283 (1980); Wolf, E.: Acta Histochem. Suppl., 35, 179 (1988); Dykewicz, M.: J. Allergy Clin. Immunol., 87 (1991)

Applications 4-(4-PHENYLBUTOXY)BENZOIC ACID (cas# 30131-16-9) is a useful research chemical.

Applications ETHYL 4-ETHOXYBENZOATE (cas# 23676-09-7) is a useful research chemical.

Applications (1,2-Dioxoethylene)bis(iminoethylene) bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate) (cas# 70331-94-1) is a useful research chemical.

Applications 3-[(4-Bromophenyl)(methyl)amino]propanoic acid (cas# 231278-20-9) is a quinazoline derivative and an aryl iodide. 3-[(4-Bromophenyl)(methyl)amino]propanoic acid has also been used in the design, synthesis and biological evaluation of quinazoline-phosphoramidate mustard conjugates as anticancer drugs.
References Zhang, Y.; et al.: Bioorg. Med. Chem. Lett., 27, 1584 (2017); Lin, S.; Eur. J. Med. Chem., 127, 442 (2017).

Stability Hygroscopic
Applications 1,1,2,2-Tetrakis(p-hydroxyphenyl)ethane (cas# 7727-33-5) is a compound useful in organic synthesis.

Applications 2-Ethylbenzene-1,4-diol (cas# 2349-70-4) is a useful research chemical.

Applications Bromocyclohexane is s used in the synthetic preparation and regioselective bromination of sp3 C-H bonds by organophotoredox catalysis.
References Kee, C.W., et al.: Asian. J. Org. Chem., 3, 536 (2014)

Applications N-Phenylmethanesulfonamide, is a building block used in the synthesis of various compounds.

Applications 5,7-Dimethoxy-2-phenylchromen-4-one is potential therapeutic agents, Polymethoxylated Flavones Isolated from Kaempferia Parviflora for cataract prevention through inhibition of matrix metalloproteinase-9 in lens epithelial cells.
References Kosano, H., et al.: Biological & Pharmaceutical Bulletin, 42, 1658-1664 (2019);

Applications Ethyl 3-Phenylpropionate is also used in the synthesis pyrimidine based inhibitors of cyclin-dependant kinases. It is also used to preparation of inhibitor BB-3497.
References Markwalder, J. et al.: J. Med. Chem., 47, 5894 (2004); Davies, S. et al.: Bioorg. Med. Chem. Lett., 13, 2709 (2003);

Applications 1,4-Diphenylbutane (cas# 1083-56-3) is a useful research chemical.

Applications 2-Hydroxybenzyl Alcohol is a phenolic component of a part of a salix bark extract which maintains a minor anti-depressant effect. Phenolic analog with potential for anti-melanomic effect
References Ulrich-M. et al.: Phytomed., 19, 930 (2012); Vad, N. et al.: Chem-Biol. Int., 183, 462 (2010);

Applications (4-(Prop-1-en-2-yl)cyclohex-1-en-1-yl)methanol is used in preparation of perilla alcohol leaf alcohol carbonate as perfume.
References Yang, S., et al.: Faming Zhuanli Shenqing, (2020);

Applications 4-Chlorobenzenethiol is a reagent used in the synthesis of small-molecule inhibitors of the protein geranylgeranyltransferase Type I (GGTase-I), acting as anti-tumor agents. Also is used in the synthesis of β-sulfanyl carbonyl compounds via Michael addition.
References Ranu, B. et al.: Tetrahedron, 60, 4183 (2004); J. Med. Chem., 43, 2310 (2000);

Applications N-Phenoxyisopropyl-N-benzylaziridinium Perchlorate is a useful intermediate in the synthesis of aziridinium ions and analogs that functions as α-adrenergic blockades.
References Henkel, J. G., et al.: J. Med. Chem., 19, 6 (1976)

Applications [(2-Bromoethyloxy)methyl]benzene is a reactant used in the preparation of muscarinic antagonist.
References Bream, R. et al.: Org. Process. Res. Dev., 17, 641 (2013); Mete, A. et al.: Bioorg. Med. Chem. Lett., 21, 7440 (2011)

Applications N-[(4-chlorophenyl)methyl]cyclopentanamine is a useful reagent for the preparation of γ-​lactams.
References Fujii, T., et al.: Tetrahedron Letters, 61, 152276 (2020)

Applications Methyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate is an antioxidant that is used in polyethylene.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Blazquez-Blazquez, Enrique. et al., ACS Omega. 16, 9055-9063(2020);

Applications Diamino-5-phenylthiazole Hydrobromide is an phenylthiazole derivative used in the preparation of antiallergic and antiinflammatory agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ban, M. et al.: Bioorg. Med. Chem., 6, 1069 (1998);

Applications 2,3-Dihydro-2,2-dimethyl-7-benzofuranol (cas# 1563-38-8) is a useful research chemical.

Applications 1,3-Dihydro-1,3-dioxo-5-isobenzofurancarboxylic Acid is an analog of Trioctyl Trimellitate (T804400) which is a plasticizer that was evaluated for endocrine disrupting activities through estrogen receptor alpha binding assay.

Stability Air Sensitive
Applications (E)-3-(4-Hydroxy-3,5-dimethoxyphenyl)acrylaldehyde (cas# 4206-58-0) is a useful research chemical.

Applications 3-hydroxycyclohexan-1-one (cas# 823-19-8) is a useful research chemical.

Applications 2-(4-Diethylamino-2-hydroxybenzoyl)benzoic Acid

Applications p-Aminophenyl Arsenoxide is a useful reagent for the study of 2-oxoacid dehydrogenase multienzyme complexes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Stevenson, et al.: Biochemistry, 17, 11, 2191 (1978)

Impurity Carbamazepine EP Impurity E
Applications 10,11-Dihydro-5H-dibenzo[b,f]azepine is a metabolite of the tricyclic antidepressant, Imipramine (I465980). 10,11-Dihydro-5H-dibenzo[b,f]azepine can be used as a chromogenic probe for the quantification of hydrogen peroxide and glucose.
References Crammer, J.L. et al.: Psychopharmacologia, 18, 26 (1970); Christiansen, J. et al.: J. Pharm. Pharmacol., 25, 604 (1973); Hackett, A.M. et al.: Xenobiotica, 14, 491 (1984); Nagaraja, P. et al.: Anal. Biochem., 395, 231 (2009);

Applications 2,4'-Dihydroxydiphenylmethane can be used in anisotropically conductive paste containing thermosetting compd. and solder particles with improved reliability.
References Ishizawa, H., et al.: Jpn. Kokai Tokkyo Koho, JP 2016066614 A 20160428 (2016);

Impurity Phenylephrine EP Impurity A
Applications rac Norphenylephrine Hydrochloride is an Impurity A of phenylephrine. A phenylephrine derivative as leukotriene D4 antagonists.
References Musser, J.H., et al.: J. Med. Chem., 30, 2087 (1987),

Applications 4-ETHYL-3-NITROBENZOIC ACID (cas# 103440-95-5) is a useful research chemical.

Stability Store Under Argon; Air Sensitive
Applications 4-Mercaptobenzoic Acid, Technical Grade (cas# 1074-36-8) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Impurity Praziquantel USP Related Compound A
Applications 2-(Descyclohexylcarbonyl)-2-benzoyl Praziquantel is used in the synthesis of Praziquantel (P702095), anthelmintic, effective against flatworms. Praziquantel USP Related Compound A
References Liu, H. et al.: Chem. Biol. Drug Des., 79, 470 (2012);

Applications 3-Cyclohexenylcarboxylic Acid has been found to be an oxidizable, nongrowth substrate and induces the metabolism of cyclohexanecarboxylic acid and benzoic acid in a strain of Pseudomonas putida. 3-Cyclohexenylcarboxylic Acid has been used as food for cultures of Streptomyces sp.  KCTC 11604BP fkbO deletion mutant to make 32-dehydroxy-FK506, a FK506 analogue containing a non-natural starter unit.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Blakley, E.R., Papish, B.: Can. J. Microbiol., 28, 1324 (1982); Ban, Y.H., et. al.: Mol. bioSystems, 9, 944 (2013)

Stability Moisture Sensitive
Applications Benzoyl Chloride is used in the manufacturing of dye intermediates.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Glotzbach, C. et al.: J. Org. Chem., 78, 4410 (2013); Coskun, A. et al.: J. Am. Chem. Soc., 127, 10464 (2005);

Applications 4-Hydroxyphenylarsonic Acid could be useful for synthesizing flower-​like CoFe2O4 particles that are an attractive sorbent for removing aromatic organoarsenicals from wastewater.
References Liu, J., et al.: J. Colloid Interface Sci., 568, 63 (2020)

Applications Methyl 3-Hydroxybenzoate (cas# 19438-10-9) is a compound useful in organic synthesis.

Applications 3-(1-Cyanoethyl)benzoic Acid is an intermediate for the synthetic preparation of various pharmaceutical compounds. 3-(1-Cyanoethyl)benzoic Acid was used in studies examining the enantioselectivity of nitrile hydratases.
References Rzeznicka, K., et al.: App. Microbiol. Biotechnol., 85, 1417 (2010); Van Pelt. S., et al.: Org. Biomole. Chem., 9, 3011 (2011);

Applications 4-Hydroxybenzylideneacetone is a reagent in the synthesis of anti-proliferative agents with 2-nitrophenylacetonitrile moieties.
References Zhang, X. et al.: Org. Biomol. Chem., 12, 355 (2014);