Anneaux à 6 chaînons

Applications 3-(Phenylmethoxy)cyclobutanemethanol is a compound useful in organic synthesis.

Applications BENZYL CYANOMETHYLCARBAMATE (cas# 3589-41-1) is a useful research chemical.

Applications 5-Phenyl-1,2,5-thiadiazolidin-3-one 1,1-Dioxide is used in the structure-based design of protein tyrosine phosphatase-1B inhibitors.
References Black, E. et al.: Bioorg. Med. Chem. Lett., 15, 2503 (2005);

Applications α-(Aminomethyl)-2-(trifluoromethoxy)benzenemethanol is an analog of α-(Aminomethyl)-3-(trifluoromethoxy)benzenemethanol (A630745); a compound that is used as a reagent in the synthesis of potent and selective ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase. It is also used as a reagent in the synthesis of 1-aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase.
References Jarvest, R.L., et al.: Bioorg. Med. Chem. Lett., 15, 2305 (2005); Keith, J.M., et al.: Bioorg. Med. Chem. Lett., 24, 1280 (2014)

Applications 7-Benzyloxy-10,11-dihydrodibenzo[b,f[[1,4]thiazepin-11-one (cas# 329217-07-4) is a compound useful in organic synthesis.

Applications [2-(4-Fluorophenyl)cyclopropyl]amine hydrochloride is a synthetic intermediate in the preparation of thiazolinone 4-monosubstituted quinolines as CDK1-Cyclin B inhibitors for use as anti-cancer agents.
References Tsai, T.Y., et al.: Bioorg. Med. Chem., 17, 2388 (2009); Vallgaarda, J., et al.: J. Med. Chem., 39, 1485 (1996);

Applications 2-(4-Hydroxybenzoyl)benzoic acid

Applications (1R,2R,4R)-rel-1,2,4-Trimethylcyclohexane is present in jet fuel-derived liquids light fractions.
References Xie, G. et al.: Env. Sci. Tech., 37, 4751 (2003); Gentner, D. et al.: Env. Sci. Tech., 47, 11837 (2013);

Applications Ethyl (1S,3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxycyclohexane-1-carboxylate, is a building block used in various chemicla synthesis. It can be used for the preparation of six stereoisomers of diaminocyclohexane carboxamide as key intermediates for synthesis of factor Xa inhibitors.
References Wang, X. et al.: Tetrahedron, Vol.73, Iss.11, P1381-1388 (2017);

Applications 4-tert-Butyl-N-phenylaniline may be useful in the synthetic preparation of amines via Buchwald-Hartwig amination reaction of aryl thioethers.
References Bismuto, A., et al.: ACS Catal., 10, 4630 (2020)

Applications 2-Cyclohexylvinylboronic Acid is used in the synthesis of vinylbenziodoxolones, a novel type of hypervalent iodine(III) reagents.
References Stridfeldt, E., et al.: Chem. Eur. J., 22, 16066-16070 (2016)

Applications 2-(5-formylfuran-2-yl)benzoic Acid (cas# 88460-72-4) is a useful research chemical.

Applications 2,5-Dimethoxybenzyl Alcohol can be used as a self-indicating standard for the determination of organolithium reagents
References Winkle, M.R. et al.: J. Chem. Soc. Chem. Comm., 3, 1980 (1980):

Applications 7-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-1,1-dioxide is used in the preparation of antihypertensive agents.
References Topliss, J. G., et al.: Journal of Medicinal Chemistry, 6, 122 (1963);

Applications 4-​Hydrazinobenzoic acid hydrochloride (cas# 24589-77-3) is a useful research chemical.

Applications N-​(3-​Dibenzofuranyl)-​5-​nitro-2-​furancarboxamide is synthesized from Dibenzo[b,d]furan-3-amine (D418205), which is a building block used as a reactant in the preparation of dibenzofuryl(phosphonomethyl)alanines as endothelin converting enzyme inhibitors.
References De Lombaert, S., et al.: J. Med. Chem., 43, 488 (2000);

Applications Methoxy4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-benzenemethanol, is prepared synthetically from vanillin (V097500) with an intermediate of methoxy-4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3-benzaldehyde (M269710).
References Gowravarm, S. et al.: Adv. Synth. Catal., 343, 169 (2001)

Applications 5-(Benzyloxy)-2-Hydroxybenzoic Acid (cas# 16094-44-3) is a useful research chemical.

Applications Substituted cinnamic and dihydrocinnamic acids show anti-inflammatory and analgesic activity, with cinnamic acids being more biologically active.
References Runwal, L. et al.: Eastern Pharmacist 38, 141 (1995)

Applications 4-Isopropylphenylacetic acid (cas# 4476-28-2) is a useful research chemical.

Applications Ethylbenzene is used in the industrial production of styrene trough various organic processes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Weiss, W. et al.: Prog. Surf. Sci., 70, 1 (2002); Cavani, F. et al.: App. Catal. A., 133, 219 (1995);

Applications Chlorocyclohexane, is a building block used in various chemical synthesis.

Applications 2-(Tetrahydro-2H-pyran-3-yl)ethanol (cas# 1050493-77-0) is a useful research chemical.

Applications Thiane, is a organic sulfide, that has shown to have antioxidant activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Chao, Q., et al.: Thermochimica Acta, 447 (2006);

Stability Moisture Sensitive
Applications Benzeneacetyl Chloride is used in the synthesis of aromatic inhibitors of HIV-1 integrase. Also used in the preparation of napthalenic ligands with high affinity for melatonin receptor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Burke, T. et al.: J. Med. Chem., 38, 4171 (1995); Yous, S. et al.: J. Med. Chem., 35, 1484 (1992);

Applications 4-phenylcyclohexanamine (cas# 19992-45-1) is a useful research chemical.

Applications 6,6-Dimethyl-3-(Methylthio)-4-Oxo-4,5,6,7-Tetrahydrobenzo[C]Thiophene-1-Carbonitrile (cas# 175202-50-3) is a useful research chemical.

Applications 3-{4-[(furan-2-ylmethyl)sulfamoyl]phenyl}prop-2-enoic acid (cas# 391229-93-9) is a useful research chemical.

Applications 4-Phenyl-1-butanol is used as a reagent in the synthesis of substituted pyrrolidine-2-carboxylic acids which are used in the treatment of AT2 receptor function associated diseases.
References McCarthy, T.D., et al. PCT Int. Appl. WO 2013102242 A1 20130711. Jul 11, 2013

Applications 2-PHENYLNICOTINIC ACID (cas# 33421-39-5) is a useful research chemical.

Applications Diphenyl (Hydroxymethyl)phosphonate is a reagent for the synthesis of amidate prodrugs of novel nucleoside phosphonate HIV reverse transcriptase (RT) inhibitor GS-9148.
References Mackman, R. L., et al.: Bioorg. Med. Chem., 18, 3606 (2010)

Applications 1,2,3-Trimethoxybenzene can be used for RSM-optimised slow pyrolysis of rice husk for bio-oil production.
References Das, S., et.al.: Energy, 225, 120161, (2021);

Applications Tetrahydro-​4H-​thiopyran-​4-​one is a cyclic carbonyl compound used as a reactant in the stereoselective preparation of [aryl(nitro)ethyl] carbonyl compounds via asymmetric Michael addition to nitroolefins catalyzed by chiral pyrrolidine-pyridine conjugate bases.
References Ishii, T., et al.: J. Am. Chem. Soc., 126, 9558 (2004);

Applications N-Benzylethylenediamine can be used to develop imidazoline derivatives as ligands for dopamine D4 receptor. It is also a reagent for enantioselective synthesis of epoxides and piperazinones.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mammoli, V., et al.: ChemMedChem 11, 1819 (2016); Meninno, S., et al.: Org. Lett. 17, 4348 (2015)

Applications Phenyl 4-Hydroxybenzoate is a substance for the production of stable exenatide preparations for treating diabetes and obesity. Investigation of drug partition property in artificial sebum for the targeted delivery of therapeutic agent into the hair and sebaceous follicles. In vitro and molecular docking studies on the side chains of parabens as modulators of antiandrogenic activities.
References Valiveti, S., et al.: Int. J. Pharm.; Zhong, H., et al.: From Faming Zhuanli Shenqing (2009), CN 101366692 A 20090218; Ding, K., et al.: Env. Sci. Technol., 51, 6452 (2017)

Applications (s)-2-phenyl-1-propanamine (cas# 17596-79-1) is a useful research chemical.

Applications A useful synthetic intermediate.

Applications Dibenzothiophene-2-boronic acid is a useful reagent for organic synthesis and other chemical processes.
References Duncton, M. A. J., et al.: Org. Lett., 10, 3259 (2008)

Applications Phenylmethyl ester N-[(3aS,4R,6S,6aR)-tetrahydro-6-hydroxy-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]-Carbamic acid is a useful chiral building block. It has been used in the synthesis of all-cis carbocyclic precursor of ticagrelor via oxidation/stereoselective reduction sequences.
References Wlodarczyk, J.; et al.: Tet. Lett., 56, 6093 (2015).

Applications 3-Hydroxy-cyclohexanone is a chemical reagent used in organic synthesis. Used in enantioselective conjugate-addition reactions as well as the cross coupling of enantioenriched secondary potassium β-trifluoroboratoamides.
References Molander, G. et al.: Adv. Synth. Catal., 355, 3037 (2013); Kitanosono, T. et al.: Chem. Asian J., 9, 179 (2014);

Applications 2-phenylcyclopentan-1-one (cas# 1198-34-1) is a useful research chemical.

Applications methyl 5-oxo-5-phenylpentanoate (cas# 1501-04-8) is a useful research chemical.

Applications 4-(Aminomethyl)-Cyclohexanecarboxylic Acid (cas# 701-54-2) is a useful research chemical.

Applications Ethyl 5-amino-1-benzofuran-2-carboxylate is used as an synthetic intermediate in the preparation of indolebutylpiperazines, a class of dual 5-HT1A receptor agonists and serotonin reuptake inhibitors. Ethyl 5-amino-1-benzofuran-2-carboxylate was also used as a potential radiolabelled analog for melanoma imaging and targeted radiotherapy.
References Chezal, J.M., et al.: J. Medn. Chem., 51, 3133 (2008); Heinrich, T., et al.: J. Medn. Chem., 47, 4684 (2004);

Applications (4-Ethynylphenyl)trimethylsilane (cas# 16116-92-0) is a useful research chemical.

Applications 4-(dimethylamino)benzenesulfonamide (cas# 6162-21-6) is a useful research chemical.

Applications (-)-DIBENZOYL-L-TARTARIC ACID MONOHYDRATE (cas# 62708-56-9) is a useful research chemical.

Applications ETHYL 4-AMINO-2-FLUOROBENZOATE (cas# 73792-06-0) is a useful research chemical.

Applications A useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters as well as dibenzyl glycosyl phosphites, which can easily be converted to glycosyl phosphates or used in glycosylation reagents in oligosaccharide synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Perich, J.W., et al.: Synthesis, 142 (1988), Wong, C-H., et al.: J. Am. Chem. Soc., 115, 2260 (1993)

Applications 2-Phenylthio-5-propionylphenylacetic Acid is a useful synthetic intermediate in the synthesis of Zaltoprofen (Z146000); an inhibitor of Cox-1 and Cox-2. Zaltoprofen preferentially inhibits Cox-2.
References Chen, W., et al.: Faming Zhuanli Shenqing. CN 1986528 A 20070627. Jun 27, 2007; Yamamoto, M., et al.: Chirality, 2, 280 (1990); Inoue, M., et al.: J Pharmacol. Exp. Ther., 293, 662 (2000)

Applications 5-Chloro-4-nitro-2,1,3-benzoselenadiazole (cas# 20718-46-1) is a compound useful in organic synthesis.
References Turesky, R., et al.: J. Agric. Food Chem., 53, 3248 (2005),

Applications 2-Cyclohexen-1-Ol (cas# 822-67-3) is a useful research chemical.

Stability Air Sensitive
Applications Can be used as a building block for chiral ligands.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2-Isobutyrylcyclohexanone (cas# 39207-65-3) is a useful research chemical.

Applications Used for induction of nitrilase activity in Arthrobacter. Used as radioprotective agent.
References Houseman, A., et al.: Biochem. 32, 4430 (1993),

Applications 2,3-Bis[4-(1,1-dimethylethyl)phenyl]-2-cyclopropen-1-one is a useful reactant and reagent for organic reactions and synthesis.
References Zhao, W., et al.: Angew. Chem., 57, 6329-32 (2018); Kong, L., et al.: Org. Lett., 19, 3644-47 (2017);

Stability Moisture Sensitive
Applications (3R,4R)-Dihydro-3,4-bis(phenylmethoxy)-2,5-furandione is an intermediate in the synthesis of N-alkenylsuccinimide derivatives.
References Ohwada, J., et al.: Bull. Chem. Soc. Jap., 63, 287 (1990);

Applications 5-[2-(Trifluoromethoxy)phenyl]-2-furancarboxylic Acid is a reactant used in the preparation of (phenyl)-N-[(mercapto)(pyrrolyl)triazolyl]furancarboxamide and (phenoxy)-N-[(mercapto)(pyrrolyl)triazolyl]acetamide derivatives as herbicides.
References Xue, S., Lu, C.: Youji Huaxue, 28, 1083 (2008)

Stability Very Moisture Sensitive
Applications Chlorotriphenylstannane is used in the synthesis of nanoparticles which bear triamide ligands.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Shariatinia, Z. et al.: Beil. J. Nanotech., 4, 94 (2013);

Stability Moisture Sensitive
Applications 1-(Trimethylsiloxy)cyclohexene is used as a reagent in the synthesis of 6-Methyl Chrysene (M265140); an aryl hydrocarbon receptor (AhR) agonist that has been listed as possibly carcinogenic to humans.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Amin, S. et al.: Cancer Res., 45, 6406 (1985); Blaha, L. et al.: Toxicol. Sci., 65, 43 (2002); Brack, W. et al.: Environ. Sci. Technol., 37, 3062 (2003); Andrysik, Z. et al.: Mutat. Res., 615, 87 (2007)