Étalons pharmaceutiques
Les standards pharmaceutiques sont un ensemble complet de matériaux de référence essentiels pour garantir la sécurité, l'efficacité et la qualité des produits pharmaceutiques. Cette catégorie comprend des standards pour les ingrédients pharmaceutiques actifs (APIs), qui sont les composants principaux responsables des effets thérapeutiques. De plus, elle couvre les composés et métabolites pertinents pour les industries pharmaceutique et vétérinaire, fournissant des points de référence pour la mesure et l'analyse précises de ces substances. Les standards de contrôle des nitrosamines sont cruciaux pour détecter et atténuer les nitrosamines potentiellement nocives dans les formulations médicamenteuses. Les standards de toxicologie aident à évaluer la sécurité et les effets indésirables potentiels des composés pharmaceutiques. En outre, les standards pour les activateurs et les inhibiteurs enzymatiques sont essentiels pour la recherche et le développement, permettant des études précises des voies biochimiques et des mécanismes des médicaments. Ces standards pharmaceutiques sont des outils indispensables pour la conformité réglementaire, le contrôle de qualité et la recherche, garantissant que les produits pharmaceutiques répondent à des critères stricts de sécurité et d'efficacité.
Sous-catégories appartenant à la catégorie "Étalons pharmaceutiques"
- APIs pour la recherche et les impuretés(274.845 produits)
- Activateurs et inhibiteurs d'enzymes(2.827 produits)
- Nitrosamines(2.605 produits)
- Composés et métabolites pharmaceutiques et vétérinaires(2.869 produits)
- Toxicologie(13.652 produits)
7836 produits trouvés pour "Étalons pharmaceutiques"
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dl-α-Tocopherol Succinate
CAS :Produit contrôléFormule :C33H54O5Couleur et forme :NeatMasse moléculaire :530.78Biotin Sulfone
CAS :Produit contrôlé<p>Applications Biotin Sulfone, is derivative of Biotin (B389040), which is a growth factor present in minute amounts in every living cell, and plays an indispensable role in numerous naturally occurring carboxylation reactions.<br>References du Vigneaud, et al.: J. Biol. Chem., 146, 475 (1942), Traub, et al.: Nature, 178, 649 (1956), Siegel, H., et al.: Experienta, 37, 789 (1981), Vesely, D.L., Science, 216, 1329 (1982), Hugues, M., et al.: Biochemistry, 31, 12 (1992),<br></p>Formule :C10H16N2O5SCouleur et forme :NeatMasse moléculaire :276.31(S)-Ramelteon Metabolite M-II
CAS :Produit contrôlé<p>Applications S-Ramelteon Metabolite M-II is a metabolite of Ramelteon in serum (M-II).<br>References Karim, A., et al.: J. Clin. Pharmacol., 44, 1210 (2004); Prescott, E., et al.: Drug Metab. Rev., 36, 203 (2004); Kato, K., et al.: Neuropharmacology, 48, 301 (2005); Karim, A., et al.: J. Clin. Pharmacol., 46, 140 (2006)<br></p>Formule :C16H21NO3Couleur et forme :NeatMasse moléculaire :275.34Methyl 3-Phenylpropionate(3-Phenylpropionic Acid Methyl Ester)
CAS :Produit contrôlé<p>Applications 3-Phenylpropionic Acid Methyl Ester is an ester derivative of 3-phenylpropionic acid that is sometimes present in fragrance ingredients.<br>References Belsito, D. et al.: Food Chem. Toxicol., 49, S256 (2011):<br></p>Formule :C10H12O2Couleur et forme :NeatMasse moléculaire :164.2Vanillin
CAS :<p>Applications The primary component of Vanilla bean extract.<br>References Nazeruddin, G., et al.: Res. J. Pharm., Biol. Chem. Sci., 2, 71 (2011), Yang, X., et al.: Biores. Technol., 102, 3498 (2011),<br></p>Formule :C8H8O3Couleur et forme :NeatMasse moléculaire :152.154-Chloro-5-sulfamoyl-salicylic Acid
CAS :<p>Applications Xipamide intermediate.<br>References Smirnov, V., et al.: Pharm. Chem. J., 34, 198 (2000),<br></p>Formule :C7H6ClNO5SCouleur et forme :NeatMasse moléculaire :251.644-Nitro-4’-aminodiphenyl Sulfone
CAS :<p>Applications An intermediate in the synthesis of the Daspone metabolite.<br></p>Formule :C12H10N2O4SCouleur et forme :NeatMasse moléculaire :278.28L-Asparagine-13C4, 15N2 Hydrate
CAS :Produit contrôléFormule :C4H815N2O3H2OCouleur et forme :NeatMasse moléculaire :138.081802Diphenhydramine N-Oxide
CAS :<p>Stability Hygroscopic<br>Applications A metabolite of Diphenhydramine (D486900) in humans.<br>References Breyer-Pfaff, U., et al.: Drug Metab. Dispos., 25, 340 (1997),<br></p>Formule :C17H21NO2Couleur et forme :NeatMasse moléculaire :271.35cis-4,7,10,13,16,19-Docosahexaenoic Acid Methyl Ester
CAS :<p>Stability Hygroscopic<br>Applications A type of biodiesel with industrial applications. Used as a reagent in cholesterol photooxidation.<br>References Hu, P.C. et al.: J. Agri. Food Chem., 50, 3572 (2002); Yu, M.J. et al.: Kor. J. Chem. Eng., 28, 2287 (2011);<br></p>Formule :C23H34O2Couleur et forme :NeatMasse moléculaire :342.51(S)-(-)-Verapamil-d3 Hydrochloride
CAS :Produit contrôlé<p>Applications (S)-(-)-Verapamil-d3 hydrochloride is deuterium labelled S-Verapamil (V124991). Both isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Peroutka, S., et al.: J. Ann. Neurol, 23, 500 (1988); Eliason, J.F., et al.: Int. J. Cancer, 46, 113 (1990)<br></p>Formule :C27H36D3ClN2O4Couleur et forme :NeatMasse moléculaire :494.08Terazosin (piperazine D8)
CAS :Produit contrôlé<p>Applications Terazosin (piperazine D8) is labelled Terazosin (T105000, HCl salt; T105005, HCl Dihydrate) which is an α-1-adrenergic blocker related to prazosin.<br>References Patterson, S.E., et al.: J. Chromatog., 311, 206 (1984); Fort, F.L., et al.: Drug Chem. Toxicol., 7, 435 (1984); Lepor, H., et al.: J. Urol., 148, 1467 (1992)<br></p>Formule :C19H17D8N5O4Couleur et forme :NeatMasse moléculaire :395.481,3-Dimethyl 2-[4-(methoxycarbonyl)-2-nitrophenyl]propanedioate
CAS :<p>Applications 1,3-Dimethyl 2-[4-(methoxycarbonyl)-2-nitrophenyl]propanedioate<br></p>Formule :C13H13NO8Couleur et forme :NeatMasse moléculaire :311.24Valeric Acid-d9
CAS :Produit contrôlé<p>Applications Valeric Acid-d9 is the isotope labelled analog of Valeric Acid which is used in biological studies of (D)-β-hydroxybutyrate which inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Taggart, A.K.P., et al.: J. Bio. Chem., 280, 26649 (2005);<br></p>Formule :C5D9HO2Couleur et forme :NeatMasse moléculaire :111.19Hydrocinnamic Acid N-Hydroxysuccinimide Ester
CAS :Produit contrôlé<p>Applications Hydrocinnamic Acid N-Hydroxysuccinimide Ester (cas# 109318-10-7) is a compound useful in organic synthesis.<br></p>Formule :C13H13NO4Couleur et forme :NeatMasse moléculaire :247.25Tranexamic-d2 Acid
CAS :Produit contrôlé<p>Applications Tranexamic-d2 acid is deuterium labelled tranexamic acid (T714505), which is an antifibrinolytic agent that blocks lysine binding sites of plasminogen. Hemostatic.<br>References Andersson, et al.: Scand. J. Haematol. 2, 230 (1965), Melander, B., et al.: Acta Pharmacol. Toxicol., 22, 340 (1965), Bonnar, J., et al.: Br. Med. J., 313, 579 (1996), Dunn, C.J., et al.: Drugs, 57, 1005 (1999),<br></p>Formule :C8H13D2NO2Couleur et forme :NeatMasse moléculaire :159.22Hydroflumethiazide
CAS :Produit contrôlé<p>Applications Antihypertensive; diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Orzech, C.E., et al.: Anal. Profiles Drug Subs., 7, 297 (1978),<br></p>Formule :C8H8F3N3O4S2Couleur et forme :NeatMasse moléculaire :331.292-Naphthylamine-d7
CAS :Produit contrôlé<p>Applications It is listed as a known human carcinogen. Used in manufacturing of dyes, as antioxidant in rubber.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References IARC Monographs, 4, 97 (1974),<br></p>Formule :C102H7H2NCouleur et forme :NeatMasse moléculaire :150.232',4'-Dihydroxyacetophenone
CAS :Produit contrôlé<p>Applications 2',4'-Dihydroxyacetophenone (cas# 89-84-9) is a compound useful in organic synthesis.<br></p>Formule :C8H8O3Couleur et forme :NeatMasse moléculaire :152.15Methyl 2,3,4-Tri-O-isobutyryl-D-glucopyranuronate
CAS :Produit contrôlé<p>Stability Temperature Sensitive<br>Applications Methyl 2,3,4-Tri-O-isobutyryl-D-glucopyranuronate (cas# 1190403-86-1) is a compound useful in organic synthesis.<br></p>Formule :C19H30O10Couleur et forme :NeatMasse moléculaire :418.44Ouabain-d3 (Major)
CAS :Produit contrôlé<p>Applications Labelled Ouabain (O714500). A cardiac glycoside that inhibits Na(+)/K(+) ATPase. It regulates transcription of MDR (increase, Pgp) and MRP (increase MRP1 and decrease CFTR, cyctic fibrosis transport receptor or cAMP-activated Cl- channel) genes, also alters localization of MRP1.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Padilha, A.S. et al.: Clin. Exp. Pharmacol. Physiol., 35, 801 (2008); Blaustein, M.P. et al.: Clin. Exp. Hypertens. 20, 691 (1998); van Huysse, J.W. et al.: Clin. Exp. Hypertens. 20, 657 (1998);<br></p>Formule :C29H41D3O12Couleur et forme :White To Off-WhiteMasse moléculaire :587.674-tert-Butylacetophenone
CAS :Produit contrôlé<p>Applications 4-tert-Butylacetophenone is an impurity arising in the synthesis of Ebastine (E320000). Ebastine impurity B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formule :C12H16OCouleur et forme :ColourlessMasse moléculaire :176.251-Nitropiperazine-d8
CAS :Produit contrôlé<p>Applications Labelled nitro substituted piperazine.<br></p>Formule :C4HD8N3O2Couleur et forme :NeatMasse moléculaire :139.18Tridecanoic-d25 Acid
CAS :Produit contrôlé<p>Applications Isotope labelled Tridecanoic Acid, commonly found in dairy products. It is also a useful synthetic intermediate. It is used to synthesize Testosterone Tridecanoate (T55180).<br>References Kliem, K., et al.: Food Chem., 141, 274 (2013);<br></p>Formule :C13D25HO2Couleur et forme :NeatMasse moléculaire :239.5Acetophenone-13C6
CAS :Produit contrôlé<p>Applications Acetophenone-13C6 is an intermediate in synthesizing Ibuprofen-13C6 (I140003), a labelled Ibuprofen. It is a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)<br></p>Formule :C213C6H8OCouleur et forme :NeatMasse moléculaire :126.1N-Nitrososarcosine-d3
CAS :Produit contrôlé<p>Applications N-Nitrososarcosine-d3 is a labelled carcinogen compound.<br>References Lu, S., et al.: Cancer Res., 46, 1485 (1986), Tricker, A., et al.: Eur. J. Cancer Prev., 6, 226 (1997),<br></p>Formule :C32H3H3N2O3Couleur et forme :Light YellowMasse moléculaire :121.11Triacetin-d9
CAS :Produit contrôlé<p>Applications Triacetin-d5 is the isotope labelled analog of Triacetin (T720850); a compound used as a food additive and flavoring. Triacetin can be used as an excipient in pharmaceutical products where it is used as a humectant, a plasticizer, and as a solvent. Triacetin can also be used as a fuel additive as an antiknock agent.<br>References Mouret, A., et al.: Green Chem., 16 (1), 269 (2014); Snejdrova, E., et al.: Inter. J. Pharma., 458, 282 (2013)<br></p>Formule :C9D9H5O6Couleur et forme :NeatMasse moléculaire :227.262,3-Dihydroxy-1,4-naphthoquinone
CAS :Produit contrôlé<p>Applications 2,3-dihydroxynaphthoquinone (cas# 605-37-8) is a useful research chemical.<br></p>Formule :C10H6O4Couleur et forme :NeatMasse moléculaire :190.15Digoxigenin Bisdigitoxoside
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications A metabolite of Digoxin (Dx) (D446575).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fujii, Y., et al.: Clin. Chem., 37, 476 (1991), Salphati, L., et al.: Xenobiotica, 29, 171 (1999), Song, S., et al.: Drug Metab. Dispos., 27, 689 (1999),<br></p>Formule :C35H54O11Couleur et forme :NeatMasse moléculaire :650.80Phosphoric Acid Tris(4-methylphenyl) Ester
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Phosphoric Acid Tris(4-methylphenyl) Ester is a human urinary organophosphate flame retardant metabolite.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Schindler, B., et al.: J. Chromat. B, 877, 375 (2009)<br></p>Formule :C21H21O4PCouleur et forme :Off-WhiteMasse moléculaire :368.362H,2H,3H,3H-Perfluorooctanoic Acid
CAS :Produit contrôlé<p>Applications 2H,2H,3H,3H-Perfluorooctanoic Acid is used in analytical studies for the identification of precursors and biodegradable products of perfluorinated and polyflorinated compounds using high resolution mass spectrometry.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yamamoto, A., et al.: Anal. Bioanal., Chem., 406, 4745 (2014)<br></p>Formule :C8H5F11O2Couleur et forme :Off-WhiteMasse moléculaire :342.11Hydroxocobalamin Acetate
CAS :Produit contrôlé<p>Applications Physiological analog of vitamin B12 where the CN group is replaced with OH. Exists in aqueous solution as an equilibrium mixture of the hydroxy isomer and the ionic aqua isomer (aquacobalamin). Precursor of the coenzymes methylcobalamin and cobamamide. Coordination Compound. Vitamin (hematopoietic).<br>References Kaczka, E.A., et al.: Science, 112, 354 (1950), Friedrich, W., et al.: Vitamins, 837 (1988), Forsyth, J.C., et al.: Clin. Toxicol., 31, 277 (1993),<br></p>Formule :C64H91CoN13O16PCouleur et forme :Dark RedMasse moléculaire :1388.39Kinetin Riboside
CAS :Produit contrôlé<p>Applications Used as an anticancer and antiviral agent.<br>References Cancer Res., 20, 1362 (1960), Virology, 38, 26 (1969),<br></p>Formule :C15H17N5O5Couleur et forme :NeatMasse moléculaire :347.33Diclofenac Acyl-β-D-glucuronide Allyl Ester
CAS :Produit contrôlé<p>Applications An intermediate for the synthesis of Diclofenac’s glucuronide metaoblite.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kenny, J.R., et al.: J. Med. Chem., 47, 2816 (2004),<br></p>Formule :C23H23Cl2NO8Couleur et forme :NeatMasse moléculaire :512.342,2'-Dihydroxy-4,4'-dimethoxybenzophenone
CAS :Produit contrôlé<p>Applications 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone (cas# 131-54-4) is a useful research chemical.<br></p>Formule :C15H14O5Couleur et forme :NeatMasse moléculaire :274.273-Ethyl Adenine-d5 (2% d0)
CAS :Produit contrôlé<p>Applications 3-Ethyl Adenine-d5 (2% d0) (cas# 147028-85-1) is a compound useful in organic synthesis.<br></p>Formule :C72H5H4N5Couleur et forme :White To Off-WhiteMasse moléculaire :168.21Pyruvic Acid-2-13C Sodium Salt
CAS :Produit contrôlé<p>Applications Labelled Pyruvic acid (P998900). Intermediate in sugar metabolism and in enzymatic carbohydrate degradation (alcoholic fermentation) where it is converted to acetaldehyde and CO2 by carboxylase. In muscle, Pyruvic acid (derived from glycogen) is reduced to lactic acid during exertion, which is reoxidized and partially retransformed to glycogen during rest. The liver can convert Pyruvic acid to alanine by amination. A diagnostic agent for Parkinson disease.<br>References Wenzel, A., et al.: J. Neurosci., 21, 53 (2001), Martinez., et al.: Development, 6, 851 (2002), Nakayama, K., et al.: J. Biochem., 146, 757 (2009), Tanaka, T., et al.: J. Pharmacol. Sci., 109, 24 (2009),<br></p>Formule :C213CH3NaO3Couleur et forme :NeatMasse moléculaire :111.04Methyl Lithocholate
CAS :Produit contrôlé<p>Applications Methyl Lithocholate is an derivative of Lithocholic Acid (L469180),a cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones.<br>References Roleira, F.M., et al.: Lett. Drug. Design. Discovery., 7, 610 (2010);<br></p>Formule :C25H42O3Couleur et forme :NeatMasse moléculaire :390.60Bisphenol A Bissulfate Disodium Salt-13C12
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Labelled a Bisphenol (B519515) derivative having antihemolytic activity.<br>References Morgan, B., et al.: Eur. J. Clin. Invest., 24, 219 (1994), Liszewski, M., et al.: Adv. Immunol., 61, 201 (1996), Assefa, H., et al.: Bioorg. Med. Chem. Lett., 9, 1889 (1999), Burdelev, O., et al.: Bioorg. Khim., 29, 159 (2003),<br></p>Formule :C3C12H14Na2O8S2Couleur et forme :NeatMasse moléculaire :444.293-Cysteinylacetaminophen-D5 (major), Trifluoroacetic Acid Salt
CAS :Produit contrôlé<p>Applications 3-Cysteinylacetaminophen-D5 (major), Trifluoroacetic Acid Salt is deuterium labeled 3-Cysteinylacetaminophen Trifluoroacetic Acid Salt (C994750), which is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).Minimum isotopic incorporation d-3, no d-0 present. A representative lot has 64% isotopic incorporation at the 6-position, 89% at the 4-position.<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Formule :C11H9D5N2O4S•C2HF3O2Couleur et forme :NeatMasse moléculaire :389.361,2-Benzenedicarboxylic Acid, mixed decyl and hexyl and octyl diesters (1:1:1 Mixture of B185420 and
CAS :Produit contrôlé<p>Applications 1,2-Benzenedicarboxylic Acid, mixed decyl and hexyl and octyl diesters_x000D_(1:1:1 Mixture of B185420 and D228455 and D228460) (cas# 68648-93-1) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Formule :C11H9D3O4Couleur et forme :ColourlessMasse moléculaire :390.5567-Hydroxy-1,3-naphthalenedisulfonic Acid Dipotassium Salt
CAS :Produit contrôlé<p>Applications 7-Hydroxy-1,3-naphthalenedisulfonic acid is a coupling component used to prepare heterocyclic monoazo dyes.<br>References Naik, D., et al., Dyes and Pigments., 14,1 (1990); Bilimoria, J., et al.: Colourage, 57, 72 (2010)<br></p>Formule :C10H6O7S2·2KCouleur et forme :Off White SolidMasse moléculaire :380.48Ramiprilat(Mixture of Diastereoisomers)
CAS :Produit contrôléFormule :C21H28N2O5Couleur et forme :NeatMasse moléculaire :388.464-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic Acid
CAS :Produit contrôlé<p>Applications 4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic Acid is used in the preparation of pentamethylnaphthylmethylbenzoates as a selective retinoid X receptor ligands that induce apoptosis in leukemia cells.<br>References Boehm, M.F., et al.: J. Med. Chem., 38, 3146-55 (1995); Furmie, J.K., et al.: ChemMedChem, 7, 1551-66 (2012)<br></p>Formule :C23H26O3Couleur et forme :NeatMasse moléculaire :350.45Diacetyl 2,4-Dinitrophenylhydrazone
CAS :<p>Applications: 2,4-Dinitrophenylhydrazone (DNPH) derivative. Also, it is used in TLC as internal standards.<br>References Lindsay, R.C., et al.: J. Food Sci., 29, 266 (1964),<br></p>Formule :C10H10N4O5Couleur et forme :NeatMasse moléculaire :266.21N-Acetylthiourea
CAS :Produit contrôlé<p>Applications N-Acetylthiourea is a derivative of Thiourea (T375450); a compound used in biochemistry to increase the solubility (and resolution) of membrane proteins in two-dimensional electrophoresis. N-Acetylthiourea can be used as a reducing agent in a two-part self curing endodontic sealing system.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jabbour, S.: Am. J. Clin. Dermatol., 4, 315 (2003); Himsworth, H.: Lancet, 242, 465 (1943); Rabilloud, T., et al.: Electrophoresis, 19, 758 (1998); Jin, S. et al. Self-curing system for endodontic sealant applications. PCT Int. Appl. WO 2009018464 A2 20090205. Feb 5, 2009<br></p>Formule :C3H6N2OSCouleur et forme :NeatMasse moléculaire :118.16N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
CAS :Produit contrôlé<p>Applications N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine is an active metabolite of Maytansine (M197940), inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer.<br>References Remillard, S., et. al.: Science, 189, 1002 (1975); Prota, A.E., et. al.: P. Natl. Acad. Sci. USA, 111, 13817 (2014)<br></p>Formule :C36H50ClN3O10SDegré de pureté :>90%Couleur et forme :NeatMasse moléculaire :752.31Ethyl Cinnamate
CAS :<p>Applications Ethyl Cinnamate, is used in the preparation of polymer-encapsulated osmonium used as a catalyst for the dihydroxylation of alkenes and preparation of a camptothecin intermediate, anticancer drug. Also used in the synthesis of substrate specific ERK1/2 inhibitors used to induce apoptosis and inhibit cell proliferation.<br>References Akiyama, R. et al.: RSC Adv., 2, 7456 (2012); Li, Q. et al.: Bioorg. Med. Chem. Lett., 19, 6042 (2009);<br></p>Formule :C11H12O2Couleur et forme :Colourless To YellowMasse moléculaire :176.21N-Acetyl-L-tyrosine
CAS :Produit contrôlé<p>Applications N-Acetyl-L-tyrosine is an analogue of L-tyrosine which stimulate the transport of L-Tyr, mainly by the ASC system.<br>References Jara, J. et al.: Melanoma Res., 1, 15 (1991),<br></p>Formule :C11H13NO4Couleur et forme :Off-WhiteMasse moléculaire :223.232-(1-Hydroxyethyl) Promazine
CAS :<p>Applications A metabolite of Acepromazine (A130900).<br>References Cossum, P., et al.: Drug Dispos., 9, 321 (1988), Stowell, L., et al.: J. Anal. Toxicol., 22, 166 (1998),<br></p>Formule :C19H24N2OSCouleur et forme :NeatMasse moléculaire :328.474,4’-Bis(4”-aminobenzenesulfonyl) Diphenyl Ether Dihydrochloride
CAS :<p>Applications The diamino arylene disulfones used in polyamido polysulfone thermoplastics and intermediates.<br></p>Formule :C24H20N2O5S2•2HClCouleur et forme :NeatMasse moléculaire :553.47Xanthurenic Acid
CAS :<p>Applications Excreted by pyridoxine-deficient animals after the ingestion of tryptophan.<br>References Aquilina, J., et al.: Biochemistry, 39, 16176 (2000), Roberts, J., et al.: Photochem. Photobiol., 74, 740 (2001),<br></p>Formule :C10H7NO4Couleur et forme :NeatMasse moléculaire :205.17Succinylacetone
CAS :<p>Applications Succinylacetone (SA) is a specific marker for the inherited metabolic disease, hepatorenal tyrosinemia. It was developed a stable-isotope for the determination of SA in dried blood spots (DBS) and liquid urine using a 13C4-SA as internal standard. The method was applied retrospectively and prospectively for the diagnosis of hepatorenal tyrosinemia and for follow-up of patients under treatment.<br>References Kvittingen, E., et al.: Inher. Metab. Dis., 14, 554 (1991), Lindstedt, S., et al.: Lancet, 340, 813 (1992), Schulze, A., et al.: Clin. Chem., 47, 1424 (2001), Allard, P., et al.: Clin. Biochem., 37, 1010 (2004),<br></p>Formule :C7H10O4Couleur et forme :White To Off-WhiteMasse moléculaire :158.15N-Nitrosodimethylamine-d6 (1 mg/mL in Methanol)
CAS :Produit contrôlé<p>Applications N-Nitrosodimethylamine-d6 (1.0 mg/mL in Methanol) is a highly toxic semi-volatile organic compound and a suspected human carcinogen. It induces liver tumors in rats after chronic exposure to low doses (1,2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br>References Chem. and Eng. News, p.5, Feb. 25, 2019<br></p>Formule :C2D6N2OCouleur et forme :Single SolutionMasse moléculaire :80.129α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one
CAS :<p>Impurity Clobetasol Propionate EP Impurity J<br>Applications 9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one (Clobetasol Propionate EP Impurity J) is an impurity in the synthesis of Clobetasol 17-Propionate (C583500), a topical corticosteroid. Glucocorticoid; anti-inflammatory.<br>References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986),<br></p>Formule :C25H30ClFO4Couleur et forme :NeatMasse moléculaire :448.957α-Thiomethyl Spironolactone-d7 (Major)
CAS :Produit contrôlé<p>Applications A labelled metabolite of Spironolactone.<br>References Gochman, N., et al.: J. Pharmacol. Exp. Ther., 135, 312 (1962), Tori, K., et al.: Steroids, 4, 713 (1964), Solymoss, B., et al.: Toxicol. Appli. Pharmacol., 18, 586 (1971),<br></p>Formule :C23H25D7O3SCouleur et forme :NeatMasse moléculaire :395.613',4',7,8-Tetrahydroxyflavone
CAS :Produit contrôlé<p>Stability Light Sensitive<br>Applications 3',4',7,8-Tetrahydroxyflavone (cas# 3440-24-2) is a useful research chemical.<br></p>Formule :C15H10O6Couleur et forme :Light YellowMasse moléculaire :286.24Clocortolone Acetate
CAS :Produit contrôlé<p>Applications Clocortolone Acetate is an intermediate in the synthesis of Clocortolone (C583800), an corticosteroid used in the treatment of skin inflammmation and other skin conditions arising for dermatoses.<br>References Rehm, K. et al.: Pharmaz. Zeit., 127, 888 (1982);<br></p>Formule :C24H30ClFO5Couleur et forme :NeatMasse moléculaire :452.943-Chlorosalicylic Acid
CAS :<p>Applications 3-Chlorosalicylic Acid (cas# 1829-32-9) is a compound useful in organic synthesis.<br>References Shackelford, J.M.: J.O.C., 26, 4908 (1961)<br></p>Formule :C7H5ClO3Couleur et forme :NeatMasse moléculaire :172.57Bromantane
CAS :Produit contrôlé<p>Applications Bromantane is an adamantane derivative used as an anxiolytic agent.<br>References Reznikov, A., et al.: Endokrinologie, 73, 11 (1979), Grekhova, T., et al.: Bull. Eksp. Biol. Med., 119, 302 (1995),<br></p>Formule :C16H20BrNCouleur et forme :White To Off-WhiteMasse moléculaire :306.242,2,6,6-Tetramethyl-4-piperidyl Methacrylate
CAS :Produit contrôlé<p>Applications It is used as cholesterol-lowering agent.<br>References Bauer, D., et al.: Polym Deg. Stab., 48, 259 (1995), Nakahara, K., et al.: Chem. Physics Lett., 359, 351 (2002),<br></p>Formule :C13H23NO2Couleur et forme :WhiteMasse moléculaire :225.33Betamethasone 17-Butyrate
CAS :Produit contrôlé<p>Applications Betamethasone 17-Butyrate is an impurity of Clobetasone 17-Butyrate (C583550), an glucocorticoid used for anti-inflammatory purposes.<br></p>Formule :C26H35FO6Couleur et forme :NeatMasse moléculaire :462.552,2'-Thiodiacetic Acid
CAS :Produit contrôlé<p>Applications 2,2'-Thiodiacetic Acid is a highly flexible ligand used in the synthesis of a series of metal complexes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hou, X., et al.: Chin. J. Struct. Chem., 32, 1339 (2013); Wu, X.X., et al.: Synth. React. Inorg. Me., 44, 486 (2014); Ma, C., et al.: J. Inorg. Organomet. P., 22, 1206 (2012)<br></p>Formule :C4H6O4SCouleur et forme :NeatMasse moléculaire :150.151,2-Cyclohexanedicarboxylic Acid Mono 4-Methyl-7-carboxy-heptyl Ester-d8
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications 1,2-Cyclohexanedicarboxylic Acid Mono 4-Methyl-7-carboxy-heptyl Ester-d8 is labelled 1,2-Cyclohexanedicarboxylic Acid Mono 4-Methyl-7-carboxy-heptyl Ester (C987315) which is a possible metabolite of the di(isononyl)cyclohexane-1,2-dicarboxylate (DINCH) monoester (MINCH).<br>References Koch, H., et al.: Arch. Toxicol., 87, 799 (2013)<br></p>Formule :C17H20D8O6Couleur et forme :NeatMasse moléculaire :336.45Desacetyl Diltiazem
CAS :<p>Impurity Diltiazem EP Impurity F<br>Applications Desacetyl Diltiazem (Diltiazem EP Impurity F) is a metabolite of Diltiazem (D460620).<br>References Shallcross, H., et al.: Br. Med. J., 295, 1236 (1987), Yeung, P.K.F., et al.: Drug Metab. Dispos., 18, 1055 (1990), Cashman, J.R., et al.: J. Med. Chem., 34,2049 (1991),<br></p>Formule :C20H24N2O3SCouleur et forme :White To BrownMasse moléculaire :372.48Nor Verapamil Hydrochloride
CAS :<p>Impurity Verapamil EP Impurity J HCl<br>Applications Nor Verapamil Hydrochloride (Verapamil EP Impurity J HCl) is a metabolite of Verapamil.<br>References Mutlib, A.E., et al.: The Journal of Pharm. & Exp. Therapeutics, 252, 2, 593 (1989)<br></p>Formule :C26H37ClN2O4Couleur et forme :WhiteMasse moléculaire :477.04Benoxaprofen
CAS :Produit contrôlé<p>Applications A non-steroidal anti-inflammatory ophthalmic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mathur, K., et al.: Bioorg. Med. Chem., 11, 1915 (2003), Zhao, M., et al.: Bioorg. Med. Chem., 15, 2815 (2007), Roy, K., et al.: Eur. J. Med. Chem., 44, 2913 (2009),<br></p>Formule :C16H12ClNO3Couleur et forme :NeatMasse moléculaire :301.723,5-Dimethyl-4-nitropyridine 1-Oxide
CAS :<p>Applications 3,5-Dimethyl-4-nitropyridine 1-Oxide is an intermediate used to prepare 2-[(2-pyridylmethyl)thio or -sulfinyl]benzimidazoles as antiulcer agents.<br>References Nohara, A., et al.: U.S., US 4689333 A 19870825. (1987)<br></p>Formule :C7H8N2O3Couleur et forme :Off White SolidMasse moléculaire :168.50Rosuvastatin Triphenylphosphonium Bromide
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications An intermediate in the production of Rosuvastatin (R700500) derivatives.<br></p>Formule :C34H34FN3O2PS·BrCouleur et forme :WhiteMasse moléculaire :678.596β-Hydroxy-21-desacetyl Deflazacort
CAS :<p>Applications The major metabolite of Deflazacort.<br>References Bernareggi, A., et al.: J. Pharma. Biomed. Anal., 5, 177-81 (1987), Assandri, A., et al.: Xenobiotica, 13(3), 185 (1983), Martinelli, E., et al.: Drug Metab. Dispos., 7, 335 (1979),<br></p>Formule :C23H29NO6Couleur et forme :NeatMasse moléculaire :415.48Digoxigenin Monodigitoxoside
CAS :Produit contrôlé<p>Applications A metabolite of Digoxin (Dx) (D446575).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fujii, Y., et al.: Clin. Chem., 37, 476 (1991), Salphati, L., et al.: Xenobiotica, 29, 171 (1999), Song, S., et al.: Drug Metab. Dispos., 27, 689 (1999),<br></p>Formule :C29H44O8Couleur et forme :BeigeMasse moléculaire :520.65Pyochelin I and Pyochelin II
CAS :Produit contrôlé<p>Impurity 2.5<br>Applications Pyochelin I and Pyochelin II are the two major siderophores produced and secreted by Pseudomonas aeruginosa PAO1 to assimilate iron. It also has trphenyltin (T809350) decomposition capacity.<br>References Braud, A., et al.: J. Bacteriol., 191, 3517 (2009); Sun, G., et al.: Appl. Environ. Microb., 72, 7264 (2006)<br></p>Formule :C14H16N2O3S2Couleur et forme :NeatMasse moléculaire :324.42Desloratadine N-Hydroxypiperidine
CAS :<p>Applications A related compound of Desloratadine (D290250).<br>References Krishna, K., et al.: J. Pharm. Biomed. Anal., 32, 29 (2003), Qi, M., et al.: J. Pharm. Biomed. Anal., 38, 355 (2005),<br></p>Formule :C19H19ClN2OCouleur et forme :NeatMasse moléculaire :326.82trans-α-Asarone
CAS :Produit contrôléFormule :C12H16O3Couleur et forme :White To Off-WhiteMasse moléculaire :208.25Potassium Bromide
CAS :<p>Applications Potassium bromide is an ionic compound that is commonly used in chemistry to form a pellet that can be used to analyze a number of compounds by means of infrared spectroscopy. Potassium bromide is also used as an anticonvulsant to treat refractory seizures in humans and dogs.<br>References Kirkland, J.: Anal. Chem., 27, 1537 (1955); Korinthenberg, R., et al.: J. Child Neuro., 22, 414 (2007); Wilberley, S., et al.: Anal. Chem., 29, 210 (1957); Yohn, S., et al.: J. Am. Vet. Med. Ass., 201, 468 (1992)<br></p>Formule :BrKCouleur et forme :White To Off-WhiteMasse moléculaire :119.00N1,N12-Diacetylspermine Dihydrochloride
CAS :<p>Stability Hygrscopic<br>Applications N1,N12-Diacetylspermine Dihydrochloride is a diacetylated derivative of Spermine (S680510) and is recognized as a novel tumor marker in patients with breast and colorectal cancers.<br>References Kato, M., et al.: Anticancer Res., 34, 3053 (2014); Umemori, Y., et al.: Clin. Chim. Acta, 411, 1894 (2010); Kawakita, M., et al.: J. Biochem., 139, 315 (2006); Hiramatsu, K., et al.: Clin. Cancer Res., 11, 2986 (2005)<br></p>Formule :C14H32Cl2N4O2Couleur et forme :NeatMasse moléculaire :359.345-Hydroxy Albuterol Hemisulfate Salt
CAS :Produit contrôlé<p>Applications The 5-hydroxy analogue of the bronchodilator, Albuterol (A514500).<br></p>Formule :C13H21NO4H2SO4Couleur et forme :NeatMasse moléculaire :304.355,7-Dimethoxycoumarin
CAS :Produit contrôlé<p>Applications 5,7-Dimethoxycoumarin is a derivitized coumarin compound.<br></p>Formule :C11H10O4Couleur et forme :NeatMasse moléculaire :206.19Azelastine N-Oxide (Mixture of Diastereomers)
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications A metabolite of Azelastine (A808250).<br>References Heinemann, U. et al.: J. Chrom. B Anal. Tech. Biomed. Life Sci., 793, 389 (2003); Tasaka, K., et al.: Arzneim.-Forsch., 29, 488 (1979);<br></p>Formule :C22H24ClN3O2Couleur et forme :NeatMasse moléculaire :397.90Pemetrexed acid
CAS :Produit contrôléFormule :C15H14N4O3Couleur et forme :Off-WhiteMasse moléculaire :298.30all-trans 5,6-Epoxy Retinoic Acid
CAS :Produit contrôlé<p>Stability Light Sensitive, Temperature Sensitive<br>Applications A metabolite of all-trans Retinoic acid (R250200).<br>References Idres, N., et al.: Cancer Res., 61, 700 (2001), Taimi, M., et al.: J. Biol. Chem., 279, 77 (2004), Vermot, J., et al.: Science, 308, 563 (2005),<br></p>Formule :C20H28O3Couleur et forme :Light YellowMasse moléculaire :316.436β-Hydroxy Progesterone (Contains up to 20% 17α-Hydroxy Progesterone)
CAS :Formule :C21H30O3Degré de pureté :>80%Couleur et forme :NeatMasse moléculaire :330.46Testololactone
CAS :Produit contrôlé<p>Applications Testololactone, is the derivative of Testolactone (T154800), which is an antineoplastic agent that is a derivative of progesterone and is used to treat advanced stage breast cancer.<br>References Dunkel, L.: Mol. Cell. Endocrinol., 254, 207 (2006); Eugster, E. A.: Treat. Endocrinol., 3, 141 (2004); Holbeck, S.L. et al.: Mol. Cancer Therap., 9, 1451 (2010);<br></p>Formule :C19H26O3Couleur et forme :White To Light YellowMasse moléculaire :302.41Gibberellin A34 (>90%)
CAS :Formule :C19H24O6Degré de pureté :>90%Couleur et forme :Light Yellow SolidMasse moléculaire :348.39Elenolic Acid (>90%)
CAS :<p>Applications Elenolic Acid is an antiviral agent that inhibits reverse transcriptases, inhibited the growth of chicken embryo fibroblast cells as well as Escherichia coli and Bacillus subtilis strains.<br>References Heinze, J.E., et al.: Antimicrob. Agents Chemother., 8, 421 (1975); Renis, H,E..: Antimicrob. Agents Chemother., 8, 149 (1975)<br></p>Formule :C11H14O6Degré de pureté :>90%Couleur et forme :NeatMasse moléculaire :242.23(S)-(+)-Ibuprofen-d3
CAS :Produit contrôlé<p>Applications A labelled nonsteroidal anti-inflammatory drug (NSAID); activity resides primarily in the (S)-isomer.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Formule :C13H15D3O2Couleur et forme :NeatMasse moléculaire :209.3Cholesterol-d6
CAS :Produit contrôlé<p>Stability Hygroscopic<br>Applications Labelled Cholesterol (C432501). Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones.<br>References Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),<br></p>Formule :C272H6H40OCouleur et forme :Off White SolidMasse moléculaire :392.696α-Bromo Beclomethasone Dipropionate
CAS :Produit contrôlé<p>Impurity Beclomethasone Dipropionate EP Impurity F<br>Applications 6α-Bromo Beclomethasone Dipropionate (Beclomethasone Dipropionate EP Impurity F) is an impurity of Beclomethasone Dipropionate (B131030).<br></p>Formule :C28H36BrClO7Couleur et forme :White SolidMasse moléculaire :599.94(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic Acid-D3
CAS :Produit contrôlé<p>Applications (3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic Acid-D3 is an intermediate used in the synthesis of Nintedanib Demethyl-O-glucuronic Acid-d3 (N478297), which is an isotopic analog of Nintedanib Demethyl-O-glucuronic Acid (N478295), a metabolite of the drug Nintedanib (N478290).<br>References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>Formule :C30D3H28N5O4Couleur et forme :NeatMasse moléculaire :528.6177-Ethyl-10-(4-N-aminopentanoic acid)-1-piperidino)carbonyloxycamptothecin
CAS :Produit contrôlé<p>Applications A major metabolite of Irinotecan.<br>References Canal, P., et al.: J. Clin. Oncol., 14, 2688 (1996), Haaz, M., et al.: Cancer Res., 58, 468 (1998), Kehrer, D., et al.: Clin. Cancer Res., 6, 3451 (2000), Hanioka, N., et al.: Xenobiotica, 31, 687 (2001), Satoh, T., et al.: Drug Metab. Dispos., 30, 488 (2002),<br></p>Formule :C33H38N4O8Couleur et forme :Light YellowMasse moléculaire :618.67686β-Hydroxy Betamethasone
CAS :Produit contrôlé<p>Applications 6β-Hydroxy Betamethasone can be used as analyte in analytical study for detecting betamethasone metabolites in human urine using liquid chromatography coupled to tandem mass spectrometry.<br>References Matabosch, X., et al.: Drug Testing and Analysis, 7, 663-672 (2015)<br></p>Formule :C22H29FO6Couleur et forme :NeatMasse moléculaire :408.46Olodaterol Hydrochloride
CAS :Produit contrôlé<p>Applications Olodaterol is a long acting β-adrenoceptor agonist used as an inhalation for treating patients with chronic obstructive pulmonary disease (COPD).<br>References Cazzola, M., et al.: Pharmacol. Rev., 64, 450 (2012); Bouyssou, T., et al.: Bioorg. Med. Chem. Lett., 20, 1410 (2010);<br></p>Formule :C21H27ClN2O5Couleur et forme :NeatMasse moléculaire :422.90Boldenone 17-Sulfate TEA
CAS :Produit contrôlé<p>Applications The major metabolite of Boldenone, an anabolic steroid.<br>References Fotsis, T., et al.: J. Steroid Biochem., 28, 203 (1987), Song, Y., et al.: Arch. Pharm. Res., 23, 599 (2000), Buiarelli, F., et al.: Anal. Chim. Acta, 526, 113 (2004), Poelmans, S., et al.: Food Addit. Contam., 22, 808 (2005),<br></p>Formule :C19H26O5S•C6H15NCouleur et forme :Off-White To BeigeMasse moléculaire :366.47N-Dechloroethyl Cyclophosphamide
CAS :<p>Stability Reacts with DMSO<br>Applications A metabolite of Cyclophosphamide (C988580).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bohnenstengel, F., et al.: Eur. J. Clin. Pharmacol., 51, 297 (1996), Busse, D., et al.: J. Clin. Oncol., 15, 188 (1997), Roy, P., et al.: Drug Metab. Dispos., 27, 655 (1999),<br></p>Formule :C5H12ClN2O2PCouleur et forme :NeatMasse moléculaire :198.59Atorvastatin Methyl Ester
CAS :Produit contrôlé<p>Applications Atorvastatin impurity. Atorvastatin Methyl Ester<br>References Graul, A., et al.: Drugs Future, 22, 956 (1997),<br></p>Formule :C34H37FN2O5Couleur et forme :White To Off-WhiteMasse moléculaire :572.671,2-Dihydro Desoxymetasone
CAS :Produit contrôlé<p>Applications A metabolite of Desoxymetasone (D296970).<br>References Schriks, M., et al.: Environ. Sci. Technol., 44, 4766 (2010), Baeck, M., et al.: Eur. J. Dermatol., 20, 102 (2010), Lee, P., et al.: Bioorg. Med. Chem. Lett., 20, 69 (2010),<br></p>Formule :C22H31FO4Couleur et forme :NeatMasse moléculaire :378.48
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