Étalons pharmaceutiques

Please enquire for more information about Acetyl-L-methionine sulfoxide including the price, delivery time and more detailed product information at the technical inquiry form on this page

(aR)-a-[[[2-(4-Nitrophenyl)ethyl]amino]methyl]benzenemethanol is a chiral, carbonyl compound that has been used in the synthesis of mirabegron. It is synthesized by reacting an amide with a hydrochloric acid salt. The product yield of (aR)-a-[[[2-(4-Nitrophenyl)ethyl]amino]methyl]benzenemethanol is high and it does not react with aluminium or amide impurities. This compound can be used for the industrial synthesis of mirabegron, which is a drug for the treatment of urinary incontinence. The reduction reaction and hydrolysis reactions are both important to this process.

2,4,6-Trichloro-5-nitropyrimidine is a purine derivative that inhibits the cell proliferation of cancer cells. It has been shown to inhibit the activity of kinases and to induce apoptosis in human cancer cells in vitro. This drug also has antiproliferative potential against erythrocytes and is being investigated as a treatment for renal disease. 2,4,6-Trichloro-5-nitropyrimidine shows inhibitory effects on the phosphorylation of roscovitine by ATP and may be used to treat patients with glomerulonephritis. 2,4,6-Trichloro-5-nitropyrimidine can be synthesized from 2,4,6-trichloropyrimidinethiol and nitric acid according to the following equation: CClNO + HNO → CClNOH + NO 2 Cl + 3 HNO

Vedaprofen is a nonsteroidal anti-inflammatory drug that belongs to the class of drugs known as NSAIDs. It inhibits the activity of the enzyme cyclooxygenase (COX), which causes inflammation and pain. Vedaprofen has been shown to be effective in treating bowel disease, inflammatory bowel disease, and autoimmune diseases, such as arthritis. Vedaprofen also has antimicrobial properties, inhibiting bacterial growth by binding to the COX enzyme in the cell membrane. The α subunit is one of the effector proteins for COX-1 and COX-2, and vedaprofen binds to this protein preventing its activation. This inhibitory effect on COX-1 and COX-2 leads to a reduction in production of prostaglandins (PGs) that are responsible for inflammatory responses. Vedaprofen may be administered orally or intravenously depending on the severity of symptoms. The oral route is preferred because it does not require

Tyrosinase protein:
Peptide Tyrosinase (Asp371) – HLA-A*0201 (YMDGTMSQV) is a human tyrosinase-derived (369-377) peptide by posttranslational conversion of the sequence YMNGTMSQV. Tyrosinase is an oxidase membrane-bound protein. Tyrosinase play a key role in the melanin synthesis pathway. Tyrosinase is presented on the surface of HLA-A*02:01 melanomas and also expressed in melanocytes. Tyrosinase has been still suggested to be a tumor antigen and might be implicated in improvement of immunotherapeutic strategies such as for efficient anticancer vaccine development.
Applications of Peptide Tyrosinase (Asp371) – HLA-A*0201 (YMDGTMSQV):
Peptide Tyrosinase (Asp371) – HLA-A*0201 (YMDGTMSQV) is used to stimulate specific cytotoxic T lymphocytes (CTL) in PBMCs and then to analyze CTL response especially the cytokine production by ELISPOT assay. Peptide Tyrosinase (Asp371) – HLA-A*0201 (YMDGTMSQV) is also involved in experimental therapies of metastatic melanoma by allogeneic hematopoietic stem cell transplantation. In fact, cytotoxic T cells were generated from peripherical blood mononuclear cells (PBMCs) of HLA-A*02:01 healthy donors after being stimulated by injection of Asp371 antigen (2). This strategy raises issues which concern the graft versus tumor (GvT) effect and graft versus host disease (GvHD).

Prednisolone is a synthetic corticosteroid that is used in the treatment of a number of lung diseases, including asthma. Prednisolone is used to decrease the inflammation and swelling around the airways and lungs. Prednisolone is used to treat certain skin conditions, such as eczema and dermatitis. This drug also decreases the activity of the immune system by inhibiting production of substances that cause inflammation. The onset of action for prednisolone is typically one day with a duration of up to two weeks. It has been shown to be more effective when taken orally than when applied topically. It may be taken with or without food and can be given as an oral or an intravenous dose. Prednisolone tablets must be dissolved in water before they are placed under the tongue (sublingual). The tablets will dissolve quickly under the tongue, releasing prednisolone into your bloodstream. Enteric-coated tablets should not be crushed or chewed

Salbutamol sulphate impurity B is a substance that is an impurity in salbutamol sulfate. It is a white crystalline powder and is soluble in organic solvents. Salbutamol sulfate impurity B can be detected by liquid chromatography, which separates the substances based on their solubility in different phases. The substances are detected at a specific wavelength, and it is possible to identify peaks of the substances on the chromatogram synchronously. Salbutamol sulfate impurity B can be found as a part of other medicines or substances by using this detection method.