Étalons pharmaceutiques

Applications Guanosine-5'-triphosphate disodium salt (CAS# 56001-37-7) is a nucleotide used in the preparation of photoreactive GTP affinity probes, and in inhibitors of eukaryotic initiation factor eIF-4E.
References George Cisar, E. A.; J. Am. Chem. Soc., 135, 4676 (2013); Ghosh, P.; et al.: Bioorg. Med. Chem. Lett., 16, 750 (2006).

Applications Triethylborane reacted with 8-hydroxyquinoline to synthesize three 8--​hydroxyquinolato (q) boron compounds B(C2H5)​2q (1)​, BPh2q (2)​, and B(2-​naph)​2q (3).
References Wu, Q., et al.: Chem. Mater., 12, 79 (2000).

Rengasin-3'-O-glucoside is a fine chemical, useful building block, and research chemical. It is a versatile building block that can be used in the synthesis of complex compounds. Rengasin-3'-O-glucoside is also a useful intermediate or scaffold for reactions. This compound has been shown to react with 1,2-ethanediol and form an ester, which can be hydrolyzed to release glycerol and the original rengasin-3'-O-glucoside.

1-(3-Fluorophenyl)-2-nitropropene is a versatile building block that can be used as a reagent, speciality chemical, or a reaction component. This compound is also useful for the synthesis of complex compounds. 1-(3-Fluorophenyl)-2-nitropropene has been shown to react with various electrophiles, including carbonyl compounds and nitro compounds, to give substituted products. This chemical is classified as a high quality compound and can be used in the synthesis of pharmaceuticals and other fine chemicals.

2,2',3,3',5,5',6,6'-Octafluorobiphenyl is a monomer that can be used for cross-coupling reactions. It can be synthesized by reacting a terminal alkyne with an organolithium compound such as cocl2. This monomer has been shown to undergo elimination reactions at lower temperatures than most other monomers and is commercially available in large quantities. 2,2',3,3',5,5',6,6'-Octafluorobiphenyl is also used as a dopant in semiconductors. The use of this compound in solar cells has been demonstrated with the addition of metal halides such as copper chloride or silver chloride. This compound has been shown to be able to efficiently absorb the light and convert it into electricity.

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Applications The formation of p-Cresol-(methyl-13C) via phenol methylation at higher temperature from the deactivation of basic catalyst.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Borodina, I. B., et al.: Russ. J. Phys. Chem., 80, 892-898 (2006)

Applications [4S-(4α,7β,7aα)]-7,7a-Dihydro-7-hydroxy-4-methoxy-4H-furo[3,2-c]pyran-2(6H)-one-13C3 is an intermediate used in the synthesis of Patulin-13C3 (P206502), which is a labelled Patulin (PAT), a mycotoxin produced by certain species of Penicillium, Aspergillus, and Byssochlamys, is mainly found in ripe apple and apple products. Patulin-induced genotoxicity and modulation of glutathione in Hep G2 cells. Antibiotic.
References Scott, P., et al.: J. Agric. Food Chem., 20, 450 (1972), Aden, D., et al.: Nature, 282, 615 (1979), Surralles, J., et al.: Mutat. Res., 341, 169 (1995), Alves, I., et al.: Mutagenesis, 15, 229 (2000), Liu, B., et al.: Toxicol. Appl. Pharmacol., 191, 255 (2003)

Naphthalene is a chemical that is used for wastewater treatment and as a pesticide. It is also used in the manufacturing of polymers, resins, and plastics. Naphthalene has antimicrobial properties due to its hydrophobic effect. Naphthalene's antimicrobial activity is based on its ability to react with the skeleton of bacterial cells and disrupt the integrity of their outer membrane. Naphthalene also interacts with proteins and DNA, causing cell death. The molecular mechanisms of naphthalene's antibacterial activity are not well understood but have been studied using Hl-60 cells, which are immortalized human monocytic leukemia cells. This study showed that naphthalene affects the cell cycle by inhibiting protein synthesis in bacteria through binding to ribosomes or by disrupting the dna replication process.

Tetrahydro-1-naphthoic acid is a toxic chemical that is used in the synthesis of various organic compounds. It is an organic acid that has a pungent odor and can cause irritation of the nose and throat. When heated, it evolves toxic fumes of hydrogen chloride gas and phosgene. Tetrahydro-1-naphthoic acid reacts with metal hydroxides to form metal tetrahydro-1-naphthoates, which have useful properties as catalysts in organic reactions. Tetrahydro-1-naphthoic acid has been used as a growth regulator in plants and animals. It binds to DNA at the C–H site, preventing protein synthesis and cell division by inhibiting RNA synthesis.

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Valeric acid is a fatty acid that is used in the manufacture of polymers. Valeric acid can be synthesized from caproic acid, which is found in palm oil and coconut oil. Valeric acid has been shown to inhibit the activity of nicotinic acetylcholine receptors at low concentrations and to have an inhibitory effect on the ryanodine receptor at high concentrations. Valeric acid also has a matrix effect on analytical methods such as gas-liquid chromatography, which has been modeled using polymer compositions.

Tetrahydro-a-(1-naphthalenylmethyl)-2-furanpropanoic Acid 2-(Diethylamino)ethyl Ester is a fatty acid analog that has antimicrobial properties. It is used in the treatment of bone cancer, and can be used to diagnose and treat other diseases such as glomerular filtration rate, receptor binding, and malonic acid. Tetrahydro-a-(1-naphthalenylmethyl)-2-furanpropanoic Acid 2-(Diethylamino)ethyl Ester binds to receptors on cells, which leads to an increase in the amount of monoamine neurotransmitters released by the cells.

4-Fluoro-3-nitrophenylacetonitrile is a monomer that can be synthesised from the reaction of carbamic acid and diphenyl ether. It is chiral, stereoselective and nucleophilic. 4-Fluoro-3-nitrophenylacetonitrile can also be synthesised by reacting fluoroacetamide with sodium cyanide in water, forming the corresponding amide, which reacts with acetonitrile to form the nitro compound. The anti-cancer properties of 4-fluoro-3 nitrophenylacetonitrile have been studied in vitro and in vivo. This substance has been shown to inhibit growth of cancer cells and induce apoptosis. In addition, this substance has been used as a synthetic strategy for dihydroisoquinolines, which are important for their anti-cancer properties.

(R)-(-)-3-Hydroxybutyric acid methyl ester is a monocarboxylic acid that is metabolized by phosphofructokinase and other enzymes to produce the corresponding 3-hydroxybutyrate. This compound is synthesized from tiglic acid, which can be obtained from corynebacterium. The production of (R)-(-)-3-Hydroxybutyric acid methyl ester can be optimized by using a biotransformation process. This process includes enzymatic reactions and chemical transformations, such as hydroxylation, carbonylation, and stereoselective synthesis. The metabolic pathway for this compound has been studied using a DNA microarray analysis.

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24(S)-Hydroxycholesterol is a cholesterol metabolite that is synthesized by the liver and can be found in human serum. It has been shown to be an important inducer of transcriptional regulation, as it regulates the expression of genes involved in lipid metabolism and inflammatory response. 24(S)-Hydoxycholesterol is also an activator of the peroxisome proliferator-activated receptor (PPAR) and may cause hepatic steatosis. This molecule has potent activity in inducing polymerase chain reaction (PCR) and protein synthesis in neuronal cells, leading to neuronal death. The molecule also induces apoptosis by caspase-independent cell death, which is mediated by mitochondrial membrane potential. 24(S)-Hydoxycholesterol may serve as a biomarker for nonsteroidal anti-inflammatory drugs (NSAIDs), with low potency against these drugs.br>

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Intermediate in the Krebs cycle; nitrogen transporter

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4-Sulpho-1,8-naphthalic anhydride potassium salt is a reagent that belongs to the family of sulfonic acids. It is used for recycling purposes in biochemical studies and for the synthesis of other compounds in organic chemistry. The chloride ion can be substituted with bromide or iodide ions to yield 4-bromobenzaldehyde. Studies have also shown that 4-SNAK can act as an electron acceptor in cellular respiration pathways and has been shown to inhibit synaptic transmission.

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Naphthenic acid is a metal chelate that is used in synchronous fluorescence spectroscopy. It has been shown to have biodegradation properties and can be used as an indicator for water quality. Naphthenic acid has been found to be a potent inhibitor of corrosion and is often used as an additive to petroleum products, such as gasoline, that are made from crude oil. Naphthenic acid also has acute toxicities and can cause toxicity studies on humans. It is able to inhibit energy metabolism in cells by binding to the mitochondrial membrane, which may be due to its ability to bind with benzalkonium chloride. Naphthenic acid can also be used for analytical methods, such as electrochemical impedance spectroscopy, because it has high sensitivity and specificity.

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