Glycosciences
La glycosciences est l'étude des glucides et de leurs dérivés, ainsi que des interactions et des fonctions biologiques auxquelles ils participent. Ce domaine de recherche est crucial pour comprendre une grande variété de processus biologiques, y compris la reconnaissance cellulaire, la signalisation, la réponse immunitaire et le développement des maladies. La glycosciences a des applications importantes en biotechnologie, en médecine et dans le développement de nouveaux médicaments et thérapies. Chez CymitQuimica, nous proposons une large sélection de produits de haute qualité et pureté pour la recherche en glycosciences. Notre catalogue comprend des monosaccharides, des oligosaccharides, des polysaccharides, des glyconjugués et des réactifs spécifiques, conçus pour soutenir les chercheurs dans leurs études sur la structure, la fonction et les applications des glucides dans les systèmes biologiques. Ces ressources sont destinées à faciliter les découvertes scientifiques et les applications pratiques dans divers domaines des biosciences et de la médecine.
Sous-catégories appartenant à la catégorie "Glycosciences"
- Aminosucres(108 produits)
- Anticorps Glyco-Related(282 produits)
- Glycolipides(46 produits)
- Glycosaminoglycanes (GAGs)(55 produits)
- Glycosides(419 produits)
- Monosaccharides(6.622 produits)
- Oligosaccharides(3.682 produits)
- Polysaccharides(503 produits)
11042 produits trouvés pour "Glycosciences"
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Methyl 5,7,8,9-tetra-O-acetyl-4-acylamino-2,6-anhydro-3,4-dideoxy-D-glycero-D-galacto-2-enonate
CAS :<p>Methyl 5,7,8,9-tetra-O-acetyl-4-acylamino-2,6-anhydro-3,4-dideoxy-D-glycero-D-galacto-2-enonate is a synthetic sugar that is used as a building block for the synthesis of polysaccharides. This compound can be modified with click chemistry and fluorination to create an array of possible saccharide structures. Methylated sugar derivatives are also used in custom synthesis applications.</p>Formule :C20H27NO12Degré de pureté :Min. 95%Masse moléculaire :473.43 g/mol3-Demethyl thiocolchicine 2-O-(2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester)
CAS :<p>3-Demethyl thiocolchicine 2-O-(2,3,4-tri-O-acetyl-b-D-glucuronide methyl ester) is a custom synthesis of 3-demethyl thiocolchicine. It is a fluorinated glycoside that can be used to synthesize oligosaccharides and monosaccharides. The modification of this substance with acetyl groups gives it a degree of solubility in organic solvents that is not found in the parent compound.</p>Formule :C34H39NO14SDegré de pureté :Min. 95%Masse moléculaire :717.74 g/mol1-O-Acetyl-2,3,5-tri-O-benzyl-b-D-ribofuranose
CAS :<p>1-O-Acetyl-2,3,5-tri-O-benzyl-b-D-ribofuranose is a synthetic sugar that has been modified with various chemical groups. It is a methylated saccharide and can be used for the synthesis of oligosaccharides or polysaccharides. 1-O-Acetyl-2,3,5-tri-O-benzyl-b-D-ribofuranose is soluble in water and ethanol. The purity of this product is greater than 98% and the CAS number is 91110–24–6.</p>Formule :C28H30O6Degré de pureté :Min. 95%Couleur et forme :Colourless syrup.Masse moléculaire :462.53 g/molBenzyl b-D-glucopyranosiduronic acid methyl ester triacetate
CAS :<p>Benzyl b-D-glucopyranosiduronic acid methyl ester triacetate is a synthetic sugar that can be modified to produce a wide range of oligosaccharides. It is suitable for glycosylation reactions, such as the synthesis of complex carbohydrates. This compound has high purity and is custom synthesized according to customer specifications. Benzyl b-D-glucopyranosiduronic acid methyl ester triacetate has been fluorinated, methylated, and monosaccharide modifications. These modifications provide this compound with many potential uses in the food industry, medicine, and other industries.</p>Formule :C20H24O10Degré de pureté :Min. 95%Masse moléculaire :424.4 g/molValproic acid b-D-glucuronide
CAS :Produit contrôlé<p>Valproic acid b-D-glucuronide is a drug that belongs to the group of anticonvulsants. Valproic acid b-D-glucuronide inhibits the activity of glutamate, which is an excitatory neurotransmitter in the brain. It also causes irreversible inhibition of GluCl channels and increases diastolic pressure. Valproic acid b-D-glucuronide has been shown to have anti-inflammatory properties, as it reduces the production of prostaglandins and cytokines. The drug has been used in animal models to study pain perception and chronic pain syndromes such as bone cancer or metabolic disorders. Valproic acid b-D-glucuronide also blocks GABA receptors, causing increased levels of gamma aminobutyric acid (GABA) and dopamine. The drug has been shown to induce a state of deep sleep in rats that are deprived from REM sleep for three weeks.</p>Formule :C14H24O8Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :320.34 g/molCMP-Neu5Gc sodium salt
CAS :<p>Please enquire for more information about CMP-Neu5Gc sodium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formule :C20H29N4Na2O17PMasse moléculaire :674.41 g/molTri-b-GalNAc-C12-amido-C3-azide
<p>Tri-b-GalNAc-C12-amido-C3-azide is a unique bifunctional ligand for ASGPR-targeted applications. The three terminal GalNAc sugars can bind to ASGPR receptors that permit hepatocyte uptake, the C12-amide linker offers a stable spacer and the C3-azide moiety enables tailored bioconjugation via CuAAC click chemistry. This design has the potential for targeted delivery of therapeutic cargo (drugs, siRNA, nanoparticles) to hepatocytes, development of LYTACs for selective protein degradation, and creation of in vivo ASGPR imaging probes.</p>Formule :C76H136N14O29Degré de pureté :Min. 95%Masse moléculaire :1,709.97 g/molTri-b-GalNAc-triazolyl-C5-amine
CAS :Tri-b-GalNAc-triazolyl-C5-amine is used for ASGPR-targeted delivery research. This molecule features three ASGPR-binding groups connected by a five-carbon alkyl (C5-alkyl) linker and a reactive amine group for attaching other molecules. When tri-b-GalNAc-triazolyl-C5-amine binds to ASGPR on cells, the entire complex is efficiently taken up into the cell and allows easy conjugation to various cargos such as RNA or Cas9 complexes, specifically to liver cells (hepatocytes). Additionally, tri-GalNAc-C5-amine can be used to create targeted chimeric molecules (LYTACs) or be attached to dyes for cellular imaging.Formule :C67H118N14O31Degré de pureté :Min. 95%Masse moléculaire :1,615.73 g/molTri-b-GalNAc-gly-C6-DBCO
Tri-b-GalNAc-Gly-C6-DBCO is used for targeted siRNA therapies for liver diseases. This synthetic molecule boasts three terminal beta-N-acetylgalactosamine (GalNAc) sugars (tri-antennary GalNAc) enabling high-affinity binding to the asialoglycoprotein receptor (ASGPR) on hepatocyte surfaces. This specific recognition promotes efficient cellular uptake of these cluster conjugates via ASGPR-mediated endocytosis. Crucially, the presence of a C6 spacer and a dibenzoeylcyclooctynone (DBCO) group allows for the attachment of siRNA molecules through bioorthogonal click chemistry. This versatile approach facilitates the development of targeted siRNA conjugates that can be delivered specifically to hepatocytes for RNA interference (RNAi) applications in the liver.Formule :C84H130N12O30Degré de pureté :Min. 95%Masse moléculaire :1,787.99 g/molTri-b-GalNAc-PEG2000-DSPE
CAS :<p>Tri-b-GalNAc-PEG2000 is a multivalent ligand containing three GalNAc moieties linked to a polyethylene glycol (PEG) spacer designed to selectively bind to the asialoglycoprotein receptor (ASGPR) expressed on hepatocytes. It can be used to create targeted drug delivery vehicles, such as liposomes or lipid nanoparticles, that specifically deliver therapeutic agents to the liver. The multivalent GalNAc ligands have high affinity for ASGPR, allowing for enhanced accumulation of drugs in the target organ while minimizing exposure to non-target tissues. The compound is typically conjugated to a phospholipid, such as 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE), to create DSPE-PEG2000-triGalNAc. This lipid-based construct can be readily incorporated into liposomes or lipid nanoparticles during formulation, enabling the development of targeted drug delivery systems.</p>Formule :(C2H4O)nC97H180N9O38PH3NDegré de pureté :Min. 95%Tri-b-GalNAc-PEG5-carboxylic acid
CAS :<p>Tri-b-GalNAc-PEG5-carboxylic acid, a trivalent beta-GalNAc ligand with a monodisperse PEG5 linker and carboxylic acid group for conjugation, targets the asialoglycoprotein receptor (ASGPR) for lysosomal degradation research (LYTACs). This facilitates efficient cargo delivery, such as RNA or Cas9 complexes, to hepatocytes.</p>Formule :C75H134N10O35Degré de pureté :Min. 95%Masse moléculaire :1,735.92 g/molTri-b-GalNAc-b-alanine-PEG3-FITC
<p>Tri-b-GalNAc-b-alanine-PEG3-FITC is a synthetic probe consisting of three GalNAc ( N-acetylgalactosamine) residues linked to a beta-alanine spacer, followed by a PEG3 linker and a fluorescein isothiocyanate (FITC) fluorophore. This probe is designed to mimic the natural glycosylation patterns found in mucins and other glycoproteins, allowing for the investigation of carbohydrate-protein interactions, particularly those involving the asialoglycoprotein receptor (ASGPR) expressed on hepatocytes. The PEG3 linker provides flexibility and spacing between the glycan and the fluorescent tag, while the FITC moiety enables the detection and tracking of the probe using fluorescence-based techniques such as flow cytometry, fluorescence microscopy, and high-throughput screening assays. This versatile tool is valuable for researchers studying glycobiology, cell-cell interactions, and the development of targeted drug delivery systems.</p>Formule :C94H143N13O37SDegré de pureté :Min. 95%Masse moléculaire :2,079.3 g/molTri-b-GalNAc-gly-biotin
<p>Tri-b-GalNAc-Gly-biotin is used for studying ASGPR-mediated processes. This molecule combines three terminal beta-N-acetylgalactosamine (GalNAc) sugars for efficient ASGPR binding with a glycine (Gly) spacer and a biotin moiety. The GalNAc moiety facilitates specific targeting to hepatocytes, while the glycine spacer provides flexibility. The terminal biotin group serves a dual purpose: it allows for straightforward purification of ASGPR-interacting molecules via affinity chromatography and enables further bioconjugation via established streptavidin-biotin conjugation strategies. This combination makes tri-b-GalNAc-Gly-biotin valuable for isolating ASGPR-binding ligands from complex mixtures, studying ASGPR-ligand interactions, and potentially developing targeted probes for in vitro and in vivo applications.</p>Formule :C73H127N13O30SDegré de pureté :Min. 95%Masse moléculaire :1,698.93 g/molTri-b-GalNAc-PEG5-sulfo-NHS ester
<p>Tri-b-GalNAc-PEG5-sulfo-NHS ester is similar to tri-b-GalNAc-PEG5-NHS ester with the difference of the presence of a sulfo group introducing a negative charge to this molecule, potentially influencing its stability and interaction with biological systems. This negatively charged group can improve water solubility further compared to uncharged PEG linkers and potentially influence the biodistribution of the conjugate. The NHS ester, which permits further conjugation, and the unique properties of the sulfo group, permit the development of unique targeted drug-GalNAc conjugates for new therapies.</p>Formule :C79H136N11NaO40SDegré de pureté :Min. 95%Masse moléculaire :1,935.03 g/mol2,3,5-Tri-O-benzyl-D-arabinofuranosyl chloride
CAS :<p>2,3,5-Tri-O-benzyl-D-arabinofuranosyl chloride is an antitumour drug that is a purine nucleoside analogue. It is a synthetic compound and has been shown to have chemotherapeutic and antitumor activities. This drug binds to the enzyme RNA polymerase II, leading to inhibition of DNA synthesis and cell death. 2,3,5-Tri-O-benzyl-D-arabinofuranosyl chloride has potential as an antitumor agent.</p>Formule :C26H27ClO4Degré de pureté :Min. 95%Masse moléculaire :438.94 g/mol4-Formylphenyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside
CAS :<p>4-Formylphenyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β--glucopyranoside is a pyranoside that is a potent inhibitor of the enzyme glycosidase. It is used to study the interactions between enzymes and substrates. The crystal structure of 4FFAP has been determined using X-ray diffraction data. This compound has a six membered ring with two acetamido groups and one carbonyl group attached to the same carbon atom in the ring. 4FFAP interacts with other molecules through hydrogen bonding and van der Waals forces.</p>Formule :C21H25NO10Degré de pureté :Min. 95%Masse moléculaire :451.42 g/mol4-Methylphenyl 2-azido-3,4,6-tri-O-(4-chlorobenzyl)-2-deoxy-b-D-thiogalactopyranoside
CAS :<p>4-Methylphenyl 2-azido-3,4,6-tri-O-(4-chlorobenzyl)-2-deoxy-b-D-thiogalactopyranoside is a synthetic glycosylation agent that has been shown to be a potent inhibitor of the synthesis of bacterial polysaccharides. It is also used in the modification of saccharides and oligosaccharides. 4MPAPG is an azide sugar that can be modified with chlorobenzyl groups by click chemistry. The resulting product is a potent inhibitor of bacterial polysaccharide production. This product has been shown to have high purity and is synthesized in custom quantities on request.</p>Formule :C34H32Cl3N3O4SDegré de pureté :Min. 95%Masse moléculaire :685.06 g/mol2-Acetamido-3-O-allyl-4,6-O-benzylidene-2-deoxy-b-D-glucopyranosyl azide
CAS :<p>2-Acetamido-3-O-allyl-4,6-O-benzylidene-2,3-deoxy-bDglucopyranosyl azide is a sugar that can be synthesized from an acetamido group and an allyl group. It is used in the synthesis of complex carbohydrates. 2A3BPGA is a monosaccharide with a glycosylation pattern of alpha 1,2. The methylation of the hydroxyl groups on the glucose rings leads to the formation of 2A3BPGAM. This modification has been shown to alter the solubility and reactivity of this sugar.</p>Formule :C18H22N4O5Degré de pureté :Min. 95%Masse moléculaire :374.4 g/mol3,4,6-Tri-O-acetyl-a-D-glucopyranose 1,2-(methyl orthoacetate)
CAS :<p>3,4,6-Tri-O-acetyl-a-D-glucopyranose 1,2-(methyl orthoacetate) is an iridoid glucoside. It has been shown to have a protective effect against eye disorders in rats and was found to have low toxicity in the eye. 3,4,6-Tri-O-acetyl-a-D-glucopyranose 1,2-(methyl orthoacetate) can be used for treatment of cardiac diseases such as heart disease. The compound may also be able to provide protection against neurologic impairment by inhibiting the production of free radicals due to its antioxidant properties.</p>Formule :C15H22O10Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :362.33 g/molCyanomethyl-2,3,4,6-tetra-O-acetyl-a-D-thiomannopyranoside
CAS :<p>Cyanomethyl-2,3,4,6-tetra-O-acetyl-a-D-thiomannopyranoside is a glycosylated thioglycoside that contains sulfur. It is used as an intermediate in the synthesis of 2′,3′,5′-trihydroxybenzaldehyde and 2′,3′,5′-trihydroxybenzoic acid.</p>Degré de pureté :Min. 95%
