Glycosciences

<p>D-Glucuronic acid, sodium salt monohydrate is a chromatographic standard. It is used to measure the hydrophilicity of a sample and its interaction with proteins. In addition, it can be used as an immunomodulator. D-Glucuronic acid, sodium salt monohydrate has been shown to have anti-inflammatory effects by inhibiting the production of prostaglandins and leukotrienes. The acidic nature of this compound may play a role in its membrane system interactions with lysine residues on protein surfaces.</p>

<p>2,3,4,6-Tetra-O-acetyl-β-D-mannopyranosyl azide is a crystallographic technique that can be used to determine the structure of molecules. This technique involves the use of x-ray diffraction analysis to produce images of crystal structures. The technique is useful for determining the three dimensional structure of molecules that are too small to be seen with other techniques such as electron microscopy.</p>

<p>3'-Sialyllacto-N-neotetraose sodium is a synthetic, fluorinated oligosaccharide with a sialic acid side chain. This compound has been shown to be an inhibitor of lacto-N-neotetraose synthesis in the human gut. It is also used as a raw material for the synthesis of various complex carbohydrates and as a click modification reagent for saccharides and polysaccharides. 3'-Sialyllacto-N-neotetraose sodium can be modified at its methyl group or sugar moiety to produce desired products.</p>

<p>5,6-O-Isopropylidene-L-gulonic acid-1,4-lactone is a synthetic monosaccharide with the molecular formula C8H14O5. It has a CAS number of 94697-68-4 and is available for custom synthesis. The chemical structure of 5,6-O-Isopropylidene-L-gulonic acid-1,4-lactone consists of a methyl group attached to the hydroxyl at position 1 and a fluoro group attached to the hydroxyl at position 4. 5,6--O--Isopropylidene--L--gulonic acid--1,4--lactone is not naturally occurring and is made by modification of glycosides. This compound can be used in click chemistry or complex carbohydrate reactions.</p>

<p>1,2,3,4-Tetra-O-pivaloyl-6-O-(tert-butyldiphenylsilyl)-b-D-galactopyranose is a high purity custom synthesis of a sugar. It is a fluorinated tetra saccharide with an unusual 1,2,3,4 linkage that has been modified with methyl groups at the 2 and 6 positions. The modification of this compound with silylation has made it resistant to enzymatic degradation. This compound has shown anti-inflammatory activities in animal models and can be used as an adjuvant therapy for inflammatory bowel disease.</p>

<p>Precursor of N-acetylneuraminic acid</p>

<p>Regulates N-glycolylneuraminic acid biosynthesis in murine liver</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>2-Acetamido-6-O-(2-acetamido-2-deoxy-a-D-galactopyranosyl)-2-deoxy-D-galactopyranose is an n-acetylated disaccharide (naturally occurring) that is a glycosidic bond between the two sugars, n-acetyl D galactosamine and 2,3,4,6 tetraacetamido 2 deoxy D galactose. This compound has an acetamide residue in place of a hydroxyl group on the second carbon atom of the sugar. The linkage between these two sugars is a glycosidic bond. In its natural form, this molecule can be found in mammalian cells and bacterial cell walls.</p>

<p>1-Deoxy-2,3:4,5:6,7-Tris-O-(1-methylethylidene)-D-glycero-D-guloheptitol is a high purity custom synthesis sugar that can be modified with fluorination and glycosylation. This product is synthesized from monosaccharides and saccharides. It has the CAS No. 1801528-80-2 and molecular weight of 354.25 g/mol. 1,2,3,4,5,6,7 -Tris (1 methylethylidene) -D glycero D gulo heptitol is a complex carbohydrate that is used in the synthesis of oligosaccharides and monosaccharides.</p>

<p>3,4:5,6-Di-O-isopropylidene-2-O-tert.butyldimethylsilyl-L-idose is a custom synthesis that is used in the synthesis of oligosaccharides and polysaccharides. It is also used for glycosylation reactions and click chemistry modifications. 3,4:5,6-Di-O-isopropylidene-2-O-tert.butyldimethylsilyl L -idose has CAS No. 53762–04–2 and a sugar type of carbohydrate. This product is a high purity with 98% or greater purity.</p>

<p>Dabigatran 4-Acyl Glucuronide is a synthetic, fluorinated glycosylation of Dabigatran etexilate. It is modified by methylation at the 2 and 3 positions to increase its stability and half-life. This compound also has a high purity with less than 0.5% of impurities and can be custom synthesized to meet specific requirements.</p>

<p>2,5-Anhydro-D-mannofuranose is a biologically active compound that belongs to the group of inorganic acids. It has been shown to be an inhibitor of heparin-induced thrombocytopenia. 2,5-Anhydro-D-mannofuranose inhibits platelet aggregation and prolongs bleeding time in rats by blocking glycosidic bond formation. This compound is also found as a constituent of oligosaccharides and nitrous oxide. Structural analysis has revealed that this molecule contains reactive groups and is acidic in nature. The analytical method for this compound is α1-acid glycoprotein. Monoclonal antibodies against fatty acid have been used for its detection in human serum.</p>

<p>B-L-Fucopyranosylamine is a Custom synthesis, Modification, Fluorination, Methylation, Monosaccharide, Synthetic, Click modification, Oligosaccharide, saccharide, Glycosylation. It has CAS No. 103419-79-0 and Carbohydrate.</p>

<p>Fuculose is a monosaccharide that is a constituent of fucose-containing glycoproteins. It is found in the blood and urine, as well as in various tissues, such as liver, lung, kidney, and spleen. The biological properties of L-fuculose are related to its ability to form hydrogen bonds with other molecules. Fuculose has been shown to be an effective activator for cutaneous lesions in mice models. The structural analysis of L-fuculose has revealed that it contains a reactive site for the synthesis of glycosaminoglycans and polysaccharides. Fuculose has also been shown to increase the proliferation of some cells, including corynebacterium glutamicum and human umbilical vein endothelial cells (HUVECs). This property may be due to its ability to activate growth factors or interfere with cell signaling pathways.</p>

<p>Alkylsophorolipids are custom-synthesized complex carbohydrates. They are composed of an oligosaccharide and methylated saccharides, which have been modified with fluorine at the C3 position. This modification increases the hydrophobicity of the molecule, which makes it more soluble in organic solvents such as chloroform. Alkylsophorolipids have a CAS number of 1269-61-6.</p>

<p>A gallotannin found in plants, with various biological activities. Its anti-cancer effect has been demonstrated in several cancer cell lines, mediated by inhibition of DNA replication, proliferation and angiogenesis. Elicits anti-inflammatory, antioxidative and anti-diabetic effects. Recently, it has been identified as an inhibitor of c-Myc in hepatocellular carcinoma and multiple myeloma cells.</p>

<p>Hyaluronate Rhodamine is a molecule that has been modified with a fluorescent dye. Hyaluronate Rhodamine is a complex carbohydrate that has been synthesized using monosaccharides, methylation, glycosylation, and polysaccharide synthesis. It is used in the study of molecular interactions due to its high purity and fluorescence properties.</p>

<p>Intermediate in the synthesis of dapagliflozin</p>

<p>L-Arabonic acid-1,4-lactone (LL) is the product of the reaction between L-arabinose and trifluoroacetic acid. LL is an enantiomer of D-arabinose and has a pK a of 6.5, which makes it a weak base. This compound has been shown to be a hydroxyl group donor in human liver and is also used as a chaperone for protein folding.</p>

<p>1,2,3,4-Tetra-O-acetyl-6-O-trityl-b-D-galactopyranose is a high purity glycosylation product. It has been custom synthesized and modified with Methylation, Click modification, Polysaccharide and Fluorination. The CAS number of this compound is 124648-92-6.</p>

<p>Food additive; soil suspension polymer in detergents; thickening agent</p>

<p>1,2,3,4-Tetra-O-benzoyl-6-O-tert-butyldiphenylsilyl-b-D-galactopyranose is a modified oligosaccharide that is synthesized and offered at high purity. The chemical name of this compound is 1,2,3,4 tetra O benzoyl 6 O tert butyldiphenylsilyl b D galactopyranose. This compound is fluorinated at the 2 position of the sugar molecule with a silyl group on the 3 position. It has CAS number 1222709-87 6.</p>

<p>Kojitriose is a disaccharide composed of two glucose molecules. It has been shown to have insulin-sensitizing effects in animals and humans. Kojitriose binds to the surface of Streptococcus faecalis and prevents the growth of this bacteria. Kojitriose also has an inhibitory effect on mesenteroides, which are a type of bacterium found in the human gut. This disaccharide is enzymatically hydrolyzed to produce hydrogen fluoride, which inhibits the growth of Streptococcus faecalis and mesenteroides. The enzyme trehalase is responsible for this hydrolysis reaction, while hydroxyl groups act as nucleophiles that react with chloride ions to form hydrogen fluoride.</p>

<p>1,2-O-Isopropylidene-3-deoxy-3-fluoro-a-D-ribofuranose is a custom synthesis. It is a complex carbohydrate that has been modified by methylation and glycosylation. This molecule has been fluorinated to produce a high purity product with the desired properties. The 1,2-O-isopropylidene group provides for increased stability and solubility of the product.</p>

<p>Please enquire for more information about 2-[(1E)-2-[6-(β-D-Galactopyranosyloxy)-2,3-dihydro-1H-xanthen-4-yl]ethenyl]-3,3-dimethyl-1-propyl-3H-indolium iodide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ulvans are structural polysaccharides present in the cell walls of green algae such as Ulva armoricana, Ulva rotondata, Ulva rigida, Ulva lacterca and Ulva pertusa.  They are highly sulphated and contain rhamnose 3-sulphate, xylose, xylose 2-sulphate, glucuronic acid and iduronic acid residues.  Ulvan has several potentially valuable functionalities such as gel formation for agricultural and food applications and possible anticoagulant, antioxidant, antihyperlipidemic and antitumor activities for pharmaceutical applications.<br>The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.</p>

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. Neoagarodecaose is reported to have potential for novel cosmeceuticals.</p>

<p>Allyl 2-O-benzoyl-3-O-benzyl-a-L-rhamnopyranoside is a complex carbohydrate that can be used in the synthesis of saccharides and polysaccharides. It has been modified by methylation, glycosylation, and carbamylation. The CAS number for this product is 940274-21-5.</p>

<p>1,2-O-IIsopropylidene -b- L- idofuranuronic acid g- lactone is a fluorinated monosaccharide that is synthesized from the glycosylation of erythritol and glycerol. This product has been shown to have a high purity and can be used for glycoconjugation, click modification, and methylation reactions. It has a CAS number of 638984-63-7.</p>

<p>This product is custom synthesized. The synthesis of this product was accomplished by modification, fluorination, methylation and monosaccharide synthesis. It is a synthetic oligosaccharide that has been modified with click chemistry. This product is made up of saccharides in a glycosylation configuration. It is a complex carbohydrate that contains sugar units in various configurations. This product has high purity and can be used as an intermediate for the synthesis of other products.</p>

<p>1,2,3,4,6-Penta-O-trimethylsilyl-D-glucopyranose is a high purity product custom synthesized for research purposes. It is a sugar that has been modified by the Click modification and fluorination. 1,2,3,4,6-Penta-O-trimethylsilyl-D-glucopyranose is an oligosaccharide with a complex carbohydrate structure that can be used in glycosylation reactions. This product is a saccharide with a CAS number of 19126-99-9.</p>

<p>1,3:4,6-Di-O-benzylidene-D-mannitol is a chiral sugar that is synthesized from d-mannitol. It is used for the preparation of polymers with acrylonitrile and phosphine. 1,3:4,6-Di-O-benzylidene-D-mannitol can be obtained by copolymerizing the monomers d-mannitol and acrylonitrile in an enantioselective manner. The yield of this compound depends on the analytical methods used to determine the composition of the polymer. The product is also used as a ligand in metal hydrides and simplifies the synthesis of chiral methyl esters.</p>

<p>2-Keto-L-galactonic acid is a chemical compound that belongs to the group of fatty acids. It is produced by the degradation of polyunsaturated fatty acids and has been shown to be a potential control agent for hepatic steatosis. 2-Keto-L-galactonic acid also inhibits the synthesis of dinucleotide phosphate in rat liver cells, leading to an accumulation of intracellular potassium ion. This compound inhibits the uptake of glucose by activating ATPase, which leads to an increase in intracellular pH. The uptake of 2-keto-L-galactonic acid into cells has been shown using cell culture experiments with wild type and mutant strains.</p>

<p>2,4-Dideoxy-2,4-difluoro-D-glucose is a fluorinated glucose analog that has been synthesized to be used as an imaging agent for positron emission tomography (PET) and single photon emission computed tomography (SPECT). It is labeled with fluorine-18 and can be metabolically incorporated into the cellular glycolytic pathway. 2,4-Dideoxy-2,4-difluoro-D-glucose emits positrons that are detected by PET or SPECT cameras. The incorporation of 2,4-dideoxy-2,4-difluoro--D--glucose into the glycolytic pathway allows it to be used as a marker for positron emission tomography.</p>

<p>Synthetic carbohydrate building block</p>

<p>Methyl 2,3,4-tri-O-acetyl-6-O-tert-butyldimethylsilyl-a-D-galactopyranoside is a synthetic glycosylated peptide that contains a 6FAM reactive group for labeling. It is a high purity product with no impurities and can be used for the fluorination of saccharides. It has a CAS number of 594841-23-3 and can be custom synthesized to meet your needs. This product is typically used as an intermediate in the synthesis of polysaccharides and oligosaccharides.</p>

<p>2-Deoxy-D-galactose is a metabolite of the carbohydrate galactose. It is found in the rat striatum and has been shown to inhibit glutamate dehydrogenase activity. 2-Deoxy-D-galactose also inhibits 2,3,4,5 tetrahydropyridine (MPTP) induced neurotoxicity in mice by increasing levels of uridine and nucleotides in the brain. This agent also has an effect on glomerular filtration rate and on protein synthesis. The glycoside derivatives of 2-deoxy-D-galactose are formed by joining a sugar molecule to hydroxyl group. These derivatives are then transported into cells via glucose transport proteins.</p>

<p>Glycosylation, complex carbohydrate, Methylation, Click modification, Polysaccharide, Fluorination, saccharide and Modification of sugars are some of the reactions that can be performed on this compound. It is a synthetic monosaccharide with CAS No. 78013-18-0. This product is available for custom synthesis and has been shown to have high purity.</p>

<p>1,4-Dideoxy-1,4-imino-D-arabinitol (1,4DA) is an inhibitor of glycolysis that has potent inhibitory activity against the enzyme phosphofructokinase. It has been shown to decrease cellular ATP levels in rat liver and kidney tissues. 1,4DA also inhibits urine production by inhibiting the conversion of fructose to glucose in the kidney. This compound is a racemic mixture with two enantiomers: R and S. The pharmacokinetics of 1,4DA have been studied in rats and humans using a model system. In rats, 1,4DA was absorbed rapidly and excreted unchanged in the urine. In humans, this drug was well absorbed after oral administration and metabolized mainly by hydrolysis to form 1,4-dideoxyfructose (Fru).</p>

<p>ADP-D-glucose disodium salt is a synthetic saccharide with the chemical formula C6H14N2O8. It is used as a building block for the synthesis of complex carbohydrates, such as polysaccharides and oligosaccharides. ADP-D-glucose disodium salt can be modified to create methylated, glycosylated, and fluorinated derivatives. These modifications allow ADP-D-glucose disodium salt to be used in Click chemistry and other advanced applications.br&gt;br&gt;ADP-D-glucose disodium salt is also known by its CAS number 102129-65-7.br&gt;br&gt; br&gt;br&gt;</p>

<p>Sodium carboxymethyl dextran is a white, odourless and tasteless powder, which is freely soluble in water or electrolyte solutions. Applications that have been described for carboxymethyl dextran include carriers of paramagnetic contrast agents, preparation of conjugates of pharmacologically active compounds and carboxymethyl dextrans in biosensors.  A number of other uses in cosmetics, agriculture, foods, paints and textiles have been the subject of patent applications.</p>

<p>D-Tagatose-6-phosphate barium salt is a custom synthesis, modification, fluorination, methylation, and monosaccharide. It has CAS No. and is a polysaccharide. D-tagatose-6-phosphate barium salt is a complex carbohydrate with glycosylation and sugar.</p>

<p>1-Deoxy-L-tagatose is a sugar that can be used as a substrate for enzymes in the glycolysis pathway. It can also be converted to d-psicose, which has been shown to have anti-inflammatory properties and may be useful as a therapeutic agent in the treatment of asthma. 1-Deoxy-L-tagatose can be used as an equilibrating agent in reactions with different sugars such as d-fructose and L-rhamnose. 1-Deoxy-L tagatose is not an isomer of L tagatose because it has one less hydroxyl group on carbon 3 on the ring. The conversion of 1 deoxy L tagatose to d psicose, however, does require hydrolysis of the epimeric bond between C1 and C2.</p>

<p>Phenyl 2-O-benzoyl-4,6-O-benzylidene-3-O-(2-naphthylmethyl)-b-D-thioglucopyranoside is a synthetic sugar with a complex carbohydrate structure. It has been modified by methylation, fluorination, and glycogenation. This product is used in the synthesis of saccharides and oligosaccharides for various purposes. Phenyl 2-O-benzoyl-4,6-O-benzylidene-3-- O-(2--naphthylmethyl)-b--D--thioglucopyranoside is CAS No. 1352561--95--5 and can be custom synthesized to meet your specifications.</p>

<p>Ezetimibe-D-glucuronide D4 is a deuterated version of the active molecule, ezetimibe. It is a white to off-white crystalline powder with a molecular weight of 592.1 Da and an empirical formula of C31H41NO7F2·C6H8O7. It is soluble in ethanol and water, and insoluble in ether or chloroform.</p>

<p>4-Methoxyphenyl 4-O-(4,6-O-benzylidene-3-O-tert-butyldimethylsilyl-2-O-levulinoyl-b-D-glucopyranosyl)-3,6-di-O-benzyl -2,6'-dideoxygalactopyranoside is a modification of the natural carbohydrate galactose. The sugar moiety has been methylated and glycosylated with a levulinate ester and then fluorinated. This compound is highly pure and can be synthesized on custom order.</p>

<p>To assess substrate specificity of galactokinase from S. pneumoniae</p>

<p>Fmoc-C-b-D-galacturonyl methylamine is a custom synthesis that is used in the modification of oligosaccharides and carbohydrates. It is also used as a precursor for the synthesis of glycosylated saccharides by methylation, glycosylation, and fluorination. Fmoc-C-b-D-galacturonyl methylamine has been shown to be an excellent starting material for the production of high purity complex carbohydrates.</p>

<p>2,3,4,6-Tetra-O-benzoyl-D-galactopyranose is a glycoside. It is synthesized by the glycosylation of galactose with benzoic acid chloride in the presence of sodium carbonate. This compound is a natural product that can be found in plants and animals. 2,3,4,6-Tetra-O-benzoyl-D-galactopyranose has been shown to inhibit topoisomerase I and II activity in mammalian cells and induce the uptake of galactose into human adenocarcinoma cells. The yields of this compound are low and it has not been studied extensively due to its limited availability.</p>