Glycosciences

This compound is generally known as sucralfates and are medications primarily taken to treat active duodenal ulcers. They are also used for the treatment of gastroesophageal reflux disease (GERD) and stress ulcers.  Sucralfate is a sucrose sulfate-aluminium complex that binds to the ulcer, creating a physical barrier that protects the gastrointestinal tract from stomach acid and prevents the degradation of mucus. It also promotes bicarbonate production and acts like an acid buffer with cytoprotective properties.

Hepta-O-acetylrutinose is a synthetic monosaccharide that is fluorinated. It can be used in the synthesis of oligosaccharides, polysaccharides, and glycosylations. Hepta-O-acetylrutinose has been shown to be useful in click chemistry and other modifications due to its reactive groups. The CAS number for this compound is 29202-64-0.

4-(3-(2,3-O-Isopropylidene-lyxofuranos-5-yl)propan-2-one-1-yl)piperidine-2,6-dione is a high purity custom synthesis sugar. It is synthesized by Click modification, Fluorination, Glycosylation and Synthetic. 4-(3-(2,3-O-Isopropylidene-lyxofuranos-5-yl)propan-2-one 1 - yl)piperidine 2,6 dione has CAS No., Oligosaccharide and Carbohydrate as its properties. It is a saccharide which belongs to the class of complex carbohydrate.

Petunidin 3-glucoside chloride is a natural compound found in the human serum and in kidney beans. It is structurally similar to chlorogenic acid, a major phenolic acid in coffee. Petunidin 3-glucoside chloride is extracted using hydrochloric acid and then purified by a surface methodology. The main degradation products of this compound are protocatechuic acid, fluorescence detector, procyanidin B4, and malonic acid. This compound can be used as an antioxidant or chemoattractant protein. It has been shown to have high levels of anthocyanins and trifluoroacetic acid (TFA) when exposed to sunlight.

Dextran sulfate sodium salt is a water-soluble polymer that is used as a drug carrier and has many applications in the pharmaceutical industry. It is an oligosaccharide with an average molecular weight of 9,000 to 16,000 Daltons. Dextran sulfate sodium salt can be used for the treatment of cavities, especially those that are infected or in which there is a risk of infection. It can also be used for intubation and has been shown to be effective at reducing allergic reactions by blocking the release of histamine by mast cells. Dextran sulfate sodium salt also has kinetic properties and can be used to study enzymatic reactions. This polymer is not toxic because it cannot be absorbed through the skin or gastrointestinal tract.

This product is a custom synthesis. The chemical formula for this product is C8H11N2O4. This product has the molecular weight of 272.24 g/mol and the molecular formula is C8H11N2O4. This product is synthesized from 3-acetamido-1-benzylazetidine-2R,4S-diyl bis(methylene) diacetate monohydrate. It can be fluorinated, glycosylated, methylated, modified and oligosaccharide or monosaccharide saccharides. This product can be used in various fields such as pharmaceuticals, agrochemicals, food additives, cosmetics and so on.

Xylose (Xyl) is an aldopentose also known as wood sugar (Collins, 2006). The main sources of xylose are hemicelluloses found in hardwood and perennial plants, such as, grasses, cereals, and herbs (Petzold-Welcke, 2014) and some algae. Xylose is used in the production of xylitol, a low calory sugar substitute. Xylose is used in glycosaminoglycan (GAG) biosynthesis, which is initiated by peptide O-xylosyltransferases, which transfer xylose onto selected serine residues in the core proteins. The first enzyme in the pathway, peptide O-xylosyltransferase, catalyzes the transfer of xylose from uridine diphosphate (UDP)-α-D-xylose onto serine and thus determines the site(s) of GAG attachment on the core protein (Briggs, 2018).

(3aS, 7S, 9S, 9aR, 9bR) -9- [[(1, 1- Dimethylethyl) dimethylsilyl] oxy] - 2, 2- diethylhexahydro- 7- methyl-1, 3- dioxolo[4, 5- a] i ndolizin- 6(4H) - one is an oligosaccharide made of sugar and saccharide. This compound is synthesized in the laboratory by clicking modification. It has a high purity and is custom synthesis. The CAS No. for this compound is 251788-72-8.

1,6-b-Galactotriose is a glycosylation product of 1,6-galactose. It is a complex carbohydrate that is found in nature and can be used for modification of saccharides, sugar, oligosaccharides, or other monosaccharides. The product is also used as a building block for the synthesis of custom polysaccharides. It can be fluorinated or methylated and click modified to produce a desired saccharide structure.

Glycyl-Oligosaccharidesmannose 3(a) (GL3(a)) is a complex carbohydrate that is composed of mannose and glycyl chains. It has been modified with methyl, click, fluorination, and saccharide modifications. GL3(a) has been synthesized using custom synthesis methods that yield high purity.

Phenyl 3-deoxy-3-fluoro-a-D-glucopyranoside is a modified oligosaccharide, which is synthesized by the glycosylation of 3,6-diaminohexanoic acid with phenyl boronic acid. This compound is also known as an anti-tuberculosis drug. It has been shown to inhibit bacterial growth by binding to DNA dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch clamp technique on human erythrocytes. Phenyl 3-deoxy-3-fluoro-a-D-glucopyranoside also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX1 secretion system protein) and inhibits cell growth in culture.

Losartan N2-glucuronide is a custom synthesis that has been modified by fluorination, methylation, and monosaccharide modification. It is synthesized with click chemistry to create an oligosaccharide. This product is synthesized from saccharides (carbohydrates) and polysaccharides. Losartan glucuronide is a complex carbohydrate that has been glycosylated and sugar modified for high purity.

Glycogen is a highly branched polysaccharide of glucose that serves as a form of energy storage in animals and fungi. It is the main storage form of glucose in the body.  In humans, glycogen is made and stored primarily in liver and muscle cells and functions as the second most important energy storage molecule to fat which is held in adipose tissue. Glycogen is analogous to starch and has a structure similar to amylopectin, but is more extensively branched and compact than starch. It occurs as granules in the cytosol/cytoplasm in many cell types, and plays an important role in the glucose cycle.

Starch consists of two polysaccharides, amylose and amylopectin and represents approximately 20-25% of the total polysaccharide content in starch. Amylose molecules consist of single mostly unbranched chains of 500-20,000 α-(1->4)-D-glucose residues dependent on source (e.g. wheat, rice, potato, tapioca, etc). Amylose can form an extended shape (hydrodynamic radius 7-22 nm) but generally tends to wind up into a rather stiff left-handed single helix or form even stiffer parallel left-handed double helical junction zones. Hydrogen bonding between aligned chains causes retrogradation and releases some of the bound water (syneresis). The aligned chains may then form double stranded crystallites that are resistant to amylases. These possess extensive inter- and intra-strand hydrogen bonding, resulting in a fairly hydrophobic structure of low solubility. The amylose content of starches is thus the major cause of resistant starch formation.

1,5-Anhydro-4,6-O-benzylidene-3-deoxy-D-glucitol (1,5BPG) is a form compound that is conformationally restricted to the chair conformation. It has inhibitory activity against human macrophages and low activity against thp-1 cells. The 1,5BPG inhibits the activation of Nlrp3 and induces apoptosis in macrophages. These effects are mediated through binding to the hydroxyl group of C2 on the glucose moiety of 1,5BPG. The 1,5BPG also has high activity against marrow derived macrophages. This is due to its ability to inhibit the synthesis of phosphatidic acid and other lipids in these cells.

Glycyl-disialyllacto-N-tetraose is a complex carbohydrate that contains a glycosidic bond between two monosaccharides. It has the molecular formula C9H18O4N2O8 and CAS number 327977-92-3. This compound can be modified with methylation, glycosylation, or fluorination to increase solubility and stability. Glycyl-disialyllacto-N-tetraose is also known as Oligosaccharide, CAS No., Polysaccharide, Modification, saccharide, Methylation, Glycosylation, Click modification and Carbohydrate.

6'-O-Acetylpaniculoside II is an oligosaccharide that contains a methylated saccharide. It has CAS No. 836-50-4 and Click modification, which is a chemical reaction between the glycone of a saccharide and an electrophile. 6'-O-Acetylpaniculoside II is also a glycosylation product of a polysaccharide and it can be custom synthesized to produce high purity carbohydrates. This compound is fluorinated for complex carbohydrate chemistry.

Glycogen phosphorylase inhibitor

Hesperetin 3'-O-b-D-glucuronide is a natural product that is synthesized by glycosylation of hesperidin with 3,4,5-trihydroxybenzoic acid. It is a synthetic and complex carbohydrate that can be modified to include fluorination, monosaccharide, oligosaccharide, methylation, and click modification. Hesperetin 3'-O-b-D-glucuronide can also be used in the synthesis of polysaccharides with glycosylations. This product has high purity and can be custom synthesized for customers.

6-O-Benzyl-1-(-)-carboxymenthyl-2,3:4,5-di-O-cyclohexylidene-L-myo-inositol is a synthetic oligosaccharide with the chemical formula C9H14FNO5. It is a monosaccharide composed of a single sugar unit, inositol, which has been modified with benzyl groups on the 6th and 1st positions of the inositol ring. This compound is used as an intermediate in the synthesis of other saccharides.

N-Acetyl-L-talosaminuronic acid is a natural product that has been shown to have anti-inflammatory activity in experimental models of inflammatory bowel disease. N-Acetyl-L-talosaminuronic acid inhibits the production of proinflammatory cytokines, such as tumor necrosis factor alpha (TNFα), by binding to TNFα receptors on the surface of cells. This can be attributed to its ability to inhibit ATP levels and reduce oxidative stress, which are both factors that contribute to inflammation. N-Acetyl-L-talosaminuronic acid also has been shown to inhibit inflammatory responses in human monocytes and neutrophils. It binds specifically to her2+ breast cancer cells and inhibits their growth in culture. Furthermore, it has been shown to have cytotoxic effects on bladder cancer cells and can be used for the treatment of bladder cancer.

Glycyl-sialyllacto-N-tetraose c is a custom synthesis of the carbohydrate polysaccharide glycyl-sialyllacto-N-tetraose. It is a complex carbohydrate that has been modified for use in biochemical research. Glycyl-sialyllacto-N-tetraose c contains four sugars, including erythrose and threose, and has been fluorinated at the C5 position. The modification of this carbohydrate was achieved through a click reaction. This product has been purified to be greater than 95% pure and is ready for use as an organic solvent or chemical reagent in laboratory experiments.

1,2:3,4:5,6-Tri-O-isopropylidene-D-gluconate is a chain sugar that is extracted from plant sources. It is a product of the methylenation of D-glucose and can be converted to D-mannitol. The reaction mixture yields dimethyl 2,3,4,5,6-tetra-O-methylene erythritol phosphate (DMEP) and diphosphate 1,2:3,4:5,6-tri-O-isopropylidene erythritol (DITEP). The DMEP can be hydrolyzed to form DME and phosphorylated to form DMPP. The crystal structure of this compound has been determined. In the elimination pathway for this compound, the gluconate group is eliminated as carbon dioxide and water with the release of energy in the form of heat. This

Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (for e.g. commensal bacteria and their products) into underlying tissue and therefore induction of inflammation.  The dextran sulphate sodium-induced ulceration model in laboratory animals has some advantages when compared to other animal models of colitis due to its simplicity and similarities to human inflammatory bowel disease. 
MW is in the range of 40,000Da

1,6-Anhydro-N,N’-diacetylchitobiose is an anhydrosugar that can be used in the synthesis of oligosaccharides

Octyl b-D-thiogalactopyranoside is a methylated derivative of galactose. It is a polysaccharide that is used to modify saccharides and oligosaccharides for research purposes. The product is used in glycosylation reactions and can be custom synthesized to meet specific requirements. Octyl b-D-thiogalactopyranoside has been modified with fluorine, which increases its stability against hydrolysis. The product is also available in high purity, making it ideal for use in synthesis reactions.

Please enquire for more information about D-Fructose 1-phosphate disodium including the price, delivery time and more detailed product information at the technical inquiry form on this page

N-Butyldeoxymannojirimycin HCl is a custom synthesis, complex carbohydrate that is synthesized from Oligosaccharides and Polysaccharides. This product is modified with Methylation, Glycosylation, and Carbohydrate. It has the CAS No. 155501-85-2 and it is high purity and fluorinated. The product can be used in Synthetic applications such as Click modification, sugar, or Fluorination.

GD1a oligosaccharide is the carbohydrate moiety from the disialylated glycosphingolipid GD1a of the a-series (shown in the sodium form), a major ganglioside found in neuronal and glial membranes. GD1a oligosaccharide has a core tetrasaccharide structure (Galβ1,3GalNAcβ1,4Galβ1,4Glc) with sialic acids linked α2,3/α2,8 to the inner galactose residue, α2,3 to the outer galactose residue (Ledeen, 2009). GD1a ganglioside interacts with myelin-associated glycoprotein (MAG) and is essential for long-term axon-myelin stability. GD1a ganglioside plays a role in viral infection as it is a receptor for viral glycoproteins in rotavirus and paramyxovirus 1. The hexasaccharide GD1a moiety was also found on a glycoprotein that acts as a receptor for adenovirus type 37. Additionally, GD1a ganglioside interacts with botulinum neurotoxin (BoNT) and is crucial for its entry into cells (Kolter, 2012).

O-(2,3,4,6-Tetra-O-acetyl-b-D-galactopyranosyl)-N-hydroxysuccinimide is a synthetic glycosylation reagent. It has the CAS number 896730-84-0 and is available for custom synthesis. O-(2,3,4,6-Tetra-O-acetyl-b-D-galactopyranosyl)-N-hydroxysuccinimide is used in the synthesis of oligosaccharides and saccharides. It is also used in click chemistry to modify proteins and other biomolecules. This product has a purity of 99% or higher and can be modified at any position with fluorination or methylation.

Methyl β-D-fructopyranoside is a glycoside that is made up of a pyranose ring and the sugar d-fructose. This molecule is stable because of its hydrogen bonds, which are formed between the oxygen atom of the hydroxyl group and the hydrogen atom of the methyl group. Methyl β-D-fructopyranoside has two chiral centers, so it can exist as two enantiomers. The most common form is D-(+)-methyl β-d-fructopyranoside, which has a configuration of R (right) and S (left).

2,3-O-Isopropylidene-5-O-tosyl-D-ribonic acid-1,4-lactone is a synthetic 2,3:5,6-diisopropylidene glycoside of D-ribose. It is a methylated sugar with an alpha-(2,3)-linked D-(+)-glucopyranosyl moiety and an alpha-(2,5)-linked L(+)-fucopyranosyl moiety. This compound can be used as a building block for the synthesis of polysaccharides and glycoconjugates. 2,3:5,6-Diisopropylidene glycoside of D-ribose is also used to synthesize oligosaccharides in carbohydrate chemistry.

Pullulan is a polysaccharide that is made up of D-glucose units linked in a beta-1,6 configuration. Pullulan has been used as a model system to study the molecular mechanisms of intramolecular hydrogen transfer reactions. The process optimization of pullulan production was studied using skin cells and structural analysis. This polymer is also used in food hydrocolloids, where it can be used to control the phase transition temperature. Pullulan has also been shown to have anti-angiogenic effects on liver cells and water vapor absorption properties.

Probenecid is a weak acid that is rapidly converted to an active metabolite in the body. It is used as an analgesic, antipyretic, and anti-inflammatory drug. Probenecid has been shown to inhibit the formation of biliary acids in animals and humans and has been used in the treatment of chronic inflammatory conditions such as rheumatoid arthritis. The most common route of administration for this drug is orally, although it can also be given intravenously or intramuscularly. Probenecid also acts as a nonsteroidal anti-inflammatory drug (NSAID). This means that it inhibits prostaglandin synthesis by blocking cyclooxygenase enzymes. This reduces inflammation, pain, and fever by inhibiting the production of prostaglandins that play a role in these processes.

This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

Methylation of a saccharide with a methyl group is called methylation. The process is used in the synthesis of many important molecules, including biomedically-relevant compounds such as drugs and natural products. Methylation can be achieved by using various methods, such as by using an organometallic (e.g., Grignard reagent) or electrophilic reagent (e.g., dimethyl sulfate).

Ethyl cellulose is an organic compound that is soluble in alcohols, acetone and ethers. It is a viscous liquid that can be dissolved in water to form a gel. Ethyl cellulose can be modified with oligosaccharides, carbohydrates, complex carbohydrates, and other substances. Ethyl cellulose has been used for the production of edible films, as well as capsules and tablets. The viscosity of ethyl cellulose can be changed by adding different substances to it. This modification allows ethyl cellulose to be customized for various purposes such as creating high purity products or glycosylation.

a-D-Glucopyranosyl fluoride is an irreversible inhibitor of the enzyme glycosidase. This product has been used to study the kinetic and mechanism of human serum alpha-glucosidase, which is a key enzyme in the digestion of carbohydrates. Kinetic studies have shown that 4-hydroxycinnamic acid and glucose are competitive inhibitors of the enzyme. The reaction mechanism for this product involves hydrogen fluoride cleavage of the glycosidic bond. The optimum pH for this product is 7.

NGA3B N-Glycan is a high purity, custom synthesis, methylation and fluorination modification of the product. This product is an oligosaccharide that is composed of saccharides and sugars. It has a CAS No. 1620146-04-4.

Lactonamycin is a linker that contains an oxygenated functional group. It can be found in some active natural products and has been synthesized in the laboratory. Lactonamycin is used as a model system for biosynthesis, where it was shown to efficiently produce glycosidic bonds when supplied with carbon sources such as glucose. The biological properties of Lactonamycin include its ability to inhibit microbial infection and inflammation, which may be due to its hydroxy group.

1-O-Acetyl-3,5-di-O-benzyl-2-deoxy-2-fluoro-[4]-thio-[D]-arabinofuranose (1OABFT) is a synthetic sugar with a high degree of methylation and glycosylation. It has been modified to be resistant to enzymes that would normally break the sugar down. 1OABFT is used in glycoproteomics research for its ability to help identify the types of sugars attached to proteins. This modification can also be used as an alternative to fluorination for improving the stability of saccharides in biological systems.

(2R, 3R) -3- [(3aR, 4R, 6aS) - 2, 2- Diethyltetrahydro- 5- (phenylmethyl) - 4H- 1, 3- dioxolo[4, 5- c] pyrrol- 4- yl] - 3-[(1, 1-dimethylethyl) dimethylsilyl]oxy]-1, 2- propanediol is a synthetic carbohydrate that is used as a building block for saccharide synthesis. It can be modified with Click chemistry to introduce reactive groups on its molecules. This compound has been shown to react with oligosaccharides and polysaccharides by glycosylation and methylation reactions. The high purity of this product makes it suitable for use in pharmaceuticals and other chemical applications.

Tert-Amyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is a custom synthesis that has not been reported in the literature or commercialized. The compound is an oligosaccharide with a fluorinated saccharide unit. It is synthesized by methylation of glycosylation and click modification of the sugar. Tert-Amyl 2-acetamido-3,4,6-tri-O-acetyl-2DGPA has been shown to be resistant to enzymatic digestion and hydrolysis by esterases. The compound can also be used as a fluorescent probe for studying carbohydrate metabolism.

Methyl 2,3-di-O-p-toluenesulfonyl-6-O-trityl-a-D-glucopyranoside is a custom synthesis of a natural product. It is an analogue of the disaccharide sucrose (CAS No. 69649-64-5). Methyl 2,3-di-O-p-toluenesulfonyl 6-[(trityloxy)methyl]-a-(1,2:4,5)-D glucopyranoside reacts with fluoride ion to form methyl 2,3 di -O - p - toluenesulfonyl 6-[(trityloxy)methyl]-a-(1,2:4,5)-D glucopyranoside fluoride ion. The monosaccharides are linked by glycosyl bonds and can be modified by different reactions such as oxidation or reduction. The saccharide can be modified

L-Idose is an aqueous solution of dextrose and anhydrous dextrose. It is a carbohydrate that provides energy to the body. L-Idose can be used to minimize the effects of certain organisms, such as bacteria, yeast, and fungi. It also helps to maintain blood glucose levels in people with diabetes by providing a source of glucose for their metabolism. L-Idose can be found in fruits and other foods that contain carbohydrates, such as breads, cereals, pastas, rice, potatoes, pasta sauces, chips, and crackers.

Methyl 4-azido-4-deoxy-2,3-O-isopropylidene-a-D-mannopyranoside is a glycosylation reagent that is used to synthesize complex carbohydrates. This product is a monosaccharide with CAS No. 682487-41-6 and has a custom synthesis. It can be fluorinated and saccharified, resulting in an oligosaccharide. The synthesis of this product is based on the Click reaction, which is an efficient way to modify sugar molecules. This product has high purity and can be custom synthesized to meet your needs.

3-Azido-3-deoxy-5,6-O-isopropylidene-D-allonic acid g-lactone is a modification of the sugar allose. It is an oligosaccharide that contains a complex carbohydrate. It can be custom synthesized and has high purity, making it suitable for use in pharmaceuticals. 3-Azido-3-deoxy-5,6-O-isopropylidene-D allonic acid g lactone is a methylated sugar, which means that it has had one of its hydroxyl groups replaced with a methyl group. It is also glycosylated, meaning that it has been modified by the addition of carbohydrates to its structure. The carbons in 3ADODAGL are found in the form of ring structures, which are known as saccharides.