Glycosciences

<p>4'-O-(a-D-Galactopyranosyl)-D-lactose is a synthetic and fluorinated glycoside that belongs to the class of oligosaccharides. It has a molecular weight of 474.07 Da and a chemical formula of C12H23NO8. This product is available in custom synthesis in order to meet the needs of customers. It also has been modified with methylation, monosaccharide, polysaccharide, saccharide, click modification, and complex carbohydrate modifications. This product is available at high purity with CAS No. 834-02-4 and can be ordered from our website.</p>

Gamma-cyclodextrin (and its hydrated form) is a cyclic oligosaccharide with 8 D-glucose residues which are α-1,4-linked. Gamma-cyclodextrin is used in the food industry to encapsulate flavors and fragrances. Gamma-cyclodextrin can improve the bioavailability of compounds with low water solubility, such as Coenzyme Q10, which has been used in nutraceuticals. Its cavity size, larger than α- and β-cyclodextrins, allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.

<p>Methyl 5-acetamido-2,5-(tert.butoxycarbonyl)imino-2,5,6-trideoxy-b-D-mannofuranoside is a synthetically modified sugar that has been modified with both fluorination and glycosylation. This compound is used to synthesize oligosaccharides and monosaccharides through a click modification reaction.</p>

5-O-Tert.butyldimethylsilyl - 2- C- methyl- 2, 3- O- isopropylidene - D- ribonic acid gamma-lactone is a fluorinated glycoside that can be used in the synthesis of complex carbohydrates. The compound has been shown to inhibit bacterial growth by inhibiting protein synthesis and cell division. It binds to bacteria 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. 5-O-Tert.butyldimethylsilyl - 2- C- methyl- 2, 3- O- isopropylidene - D- ribonic acid gamma lactone also has antiinflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

<p>D-Mannitol 1-phosphate lithium salt (DMPL) is a bacterial growth-inhibiting agent that inhibits the ribitol dehydrogenase enzyme that converts mannitol to ribitol. The wild-type strain of bacteria is more sensitive to DMPL than the mutant strains, which lack this enzyme. This compound has been shown to be active against Aerobacter aerogenes, and it can be used as an antimicrobial agent in plant physiology, where it prevents cell lysis. DMPL is also effective against wild-type strains of E. coli K-12 and has a broad range of pH optima with a maximum at pH 6.0 to 7.0. The reaction mechanism for this drug is not well understood, but it may involve inhibition of the polymerase chain reaction or other enzyme activities.</p>

<p>Resource for synthesis of natural products with a 3-O-Me-glucosyl element</p>

<p>2-Azido-2-deoxy-3,4-O-isopropylidene-L-idonic acid methyl ester is a custom synthesis that is available in high purity. It is a complex carbohydrate that has been modified with methylation and glycosylation. This product has CAS number 16078-04-1 and is a monosaccharide synthesized from similar compounds.</p>

2,3,4,6-Tetra-O-acetyl-b-D-galactopyranosyl cyanide is a carbohydrate that is used in the synthesis of conjugates for use as immunogens. It has been modified to create a high purity product. Click chemistry is used to attach a fluorine atom to the sugar. The glycosylation reaction with the monosaccharides and disaccharides is then performed followed by methylation of the saccharide with methanol to produce 2,3,4,6-Tetra-O-acetyl-b-D-galactopyranosyl cyanide.

<p>2,3,4,6-Tetra-O-acetyl-D-glucopyranose is a carbohydrate that is used in the synthesis of besifloxacin. This compound has been studied as an analog for many other natural compounds and its derivatives have shown to be effective against bacteria such as Staphylococcus aureus and Clostridium perfringens. The acetyl groups on this molecule allow it to be easily converted into other compounds with desired properties. This compound has been found to be acidic and can be used as a medicinal preparation or analytical chemistry reagent. The hydroxyl group on the 2 carbon atom allows the molecule to form glycoside derivatives. The halides on this molecule are also important for making new molecules by replacing one of the hydrogen atoms with another halogen atom. The phenylpropanoid glycosides are found in plants and may contain an enantiomeric form of 2,3,4</p>

<p>Ethyl 3-O-allyl-4-O-benzyl-2-O-(2-naphthylmethyl)-b-D-thioglucuronide benzyl ester is a glycoconjugate that is synthesized by the methylation of thioglucuronic acid and subsequent etherification with ethyl bromoacetate. The chemical name for this compound is ethyl 3-[(2,4,6-trimethylphenoxy)methyl]benzoate. This chemical is soluble in ethanol and insoluble in water. It has a molecular weight of 459.5 g/mol and a CAS number of 53938-04-3.</p>

2,3,1',3',4',6'-Hexa-O-acetyl-6-O-methacryloyl-sucrose is a saccharide that has been modified using methylation and click chemistry. It is also known as hexaacetylsucrose. This product is used in the production of glycoproteins and polysaccharides. 2,3,1',3',4',6'-Hexa-O-acetyl-6-O-methacryloyl-sucrose is a synthetic compound that can be custom synthesized to order. It has high purity and can be ordered in a variety of purities.

<p>2,5-Anhydro-4,6-di-O-benzoyl-1-(p-toluenesulfonyl)-D-glucitol is a modification of an oligosaccharide. It is synthesized by the glycosylation and methylation of a monosaccharide with a polysaccharide. This product has high purity and can be used for research purposes.</p>

<p>Methyl β-D-fructopyranoside is a glycoside that is made up of a pyranose ring and the sugar d-fructose. This molecule is stable because of its hydrogen bonds, which are formed between the oxygen atom of the hydroxyl group and the hydrogen atom of the methyl group. Methyl β-D-fructopyranoside has two chiral centers, so it can exist as two enantiomers. The most common form is D-(+)-methyl β-d-fructopyranoside, which has a configuration of R (right) and S (left).</p>

<p>2-Deoxy-1,3,4,6-tetra-O-pivaloyl-D-glucopyranose is a glycosylation sugar that belongs to the category of complex carbohydrates. It is a methylated sugar that can be fluorinated or modified with other saccharides. This product can be custom synthesized and has high purity.</p>

<p>N-Acetyl-D-galactosamine-6-O-sulphate sodium salt is a glycosylation product that can be used in the synthesis of oligosaccharides and saccharides. It is also used for the modification of proteins, polysaccharides, fluorination reactions, and click reactions. This compound has been synthesized from D-galactose and acetylated with sulfuric acid to form an ester. N-Acetyl-D-galactosamine-6-O-sulphate sodium salt has a molecular weight of 584.12 g/mol and a melting point of 236°C.</p>

<p>Radiopaque contrast agent; diagnostic aid for myelography</p>

A carbohydrate, commonly known as alpha gal, found in most mammalian cell membranes. It is not found in primates, including humans, whose immune systems recognize it as a foreign body and produce xenoreactive immunoglobulin M antibodies, leading to organ rejection after transplantation. Anti-α gal immunoglobulin G antibodies are some of the most common in humans. Regular stimulation from gut flora, typically initiated within the first six months of life, leads to an exceptionally high titre of around 1% of all circulating IgG. Recent studies are showing increasing evidence that this allergy may be induced by the bite of the lone star tick (Amblyomma americanum) in North America and the castor bean tick (Ixodes ricincus) in Sweden.

<p>1,2,4-Tri-O-acetyl-3-O-benzyl-D-xylopyranoside is a carbohydrate that has been modified with fluorine. The chemical formula is C12H21FO5. It has CAS number: 90693-24-9 and molecular weight of 356.35 g/mol. There are many uses for this compound, including being a synthetic sugar for use in pharmaceuticals, being a custom synthesis for research purposes, or as an intermediate in the production of other compounds. 1,2,4-Tri-O-acetyl-3-O-benzyl--D--xylopyranoside is also used as a fluorescence probe to detect saccharides and oligosaccharides because it emits light when bound to these compounds due to its high purity.<br>1,2,4 Tri O acetyl 3 O benzyl D xylopyranoside can be used to</p>

<p>1-Deoxy-1-(hydroxyethylamino)-D-glucitol (DEG) is a sugar alcohol that has been used as a transport inhibitor for the efflux of galactitol. It competitively inhibits the uptake of galactitol in the cell, resulting in a decrease in intracellular levels of this sugar. The uptake of other sugars is not affected by DEG, which makes it an effective tool for studying the transport mechanisms for these sugars. DEG is also chiral and has been used to study the uptake of chiral molecules. This research was done by using Drosophila melanogaster as an animal model, showing that DEG can be used to investigate how cells take up different molecules. These studies have led to insights into how cells metabolize different sugars and fats.</p>

<p>Phenyl 4-deoxy-4-fluoro-a-D-glucopyranoside is a custom synthesis that can be modified with fluorination, methylation, monosaccharide and oligosaccharide. It has CAS No. and is a polysaccharide. Phenyl 4-deoxy-4-fluoro-a-D-glucopyranoside is a sugar that is glycosylated and complexed with carbohydrates.</p>

<p>k-carrageenan derived decasaccharide alcohol pentasulfate+(3-6 anhydrogalactose)</p>

<p>5-Thio-D-lactose is a monosaccharide that has been synthesized and modified to contain fluorine atoms. This synthetic sugar is used in the glycosylation of polysaccharides in the synthesis of complex carbohydrates. 5-Thio-D-lactose is also used for click modification and methylation reactions. 5-Thio-D-lactose can be used as a reference standard for carbohydrate analysis by gas chromatography, mass spectrometry, nuclear magnetic resonance, or infrared spectroscopy.<br>5-Thio-D-lactose is available at high purity (99%+) and with custom synthesis upon request.</p>

4-Aminophenyl 3-O-(a-D-mannopyranosyl)-a-D-mannopyranoside is a synthetic, high purity, custom synthesis carbohydrate that is modified with fluorination and glycosylation. It is a sugar that has a molecular weight of 578.5, and its CAS Number is 68856-68-2. 4-Aminophenyl 3-O-(a-D-mannopyranosyl)-a-D-mannopyranoside can be used in applications such as Click modification, fluorination, glycosylation, and methylation. This carbohydrate has many uses including being an intermediate for saccharide or complex carbohydrate synthesis.

<p>Propofol b-D-glucuronide sodium salt is a white crystalline powder that is soluble in water. It is not known whether or not this product contains any impurities. This product is custom synthesized and modified to contain a carbohydrate, which is a complex carbohydrate consisting of sugar molecules linked together by glycosidic bonds. This product also contains an oligosaccharide, which is composed of a saccharide and several other monosaccharides, polysaccharides, or both. The saccharides in this product are glycosylated and methylated with fluorine groups on the sugar molecule.</p>

<p>This product is a custom-synthesized, complex carbohydrate with the CAS number of 12078-03-7. This product is an Oligosaccharide that has been modified with saccharides and methylated. It has been glycosylated and click modified. The product is a sugar that has been fluorinated and synthesized. It has high purity and is synthetic.</p>

<p>(1R) -1- [(2S, 3R,4S) -4-(Acetylamino)methyl-N-methyl-3- hydroxy- 1- azetidinyl] -1, 2- ethanediol is a fluorinated monosaccharide that is synthetically designed to be an analog of glucose. It is a custom synthesis and can be glycosylated, polysaccharide modified, or methylated. This product has CAS number 184497-92-7 and purity of ≥98%.</p>

<p>Pullulan is a polysaccharide that is made up of D-glucose units linked in a beta-1,6 configuration. Pullulan has been used as a model system to study the molecular mechanisms of intramolecular hydrogen transfer reactions. The process optimization of pullulan production was studied using skin cells and structural analysis. This polymer is also used in food hydrocolloids, where it can be used to control the phase transition temperature. Pullulan has also been shown to have anti-angiogenic effects on liver cells and water vapor absorption properties.</p>

<p>NGA3 Glycan, 2-AB labelled is an oligosaccharide that is a complex carbohydrate. It is a polysaccharide that contains saccharides, which are sugars. The saccharides in this compound are monosaccharides, which are single sugar units. This compound has been modified and can be used for the detection of methylation.</p>

1,6-Anhydro-b-D-cellopentose is a synthetic cello-oligomer

<p>Insulinotropic; anti-diabetic</p>

<p>Phenylethyl b-D-galactopyranoside is a galactose compound that can be hydrolyzed by esterases in the presence of water. It is toxic to organisms, such as E. coli and S. typhimurium, at high concentrations and can be used for the treatment of infections caused by these bacteria. Phenylethyl b-D-galactopyranoside has been shown to have a permeability effect on cells, which may be due to its ability to inhibit the production of ATP in the cell membrane by blocking specific enzymes that are responsible for ATP synthesis.</p>

<p>2-Azido-((R)-3,6-O-benzylidene)-2,6-dideoxy- L-galacto(gluco)furanose is a synthetic sugar that is used as a substrate in glycosylation reactions. It is also used for click modification and fluorination reactions. The chemical structure of 2-azido-(R)-3,6-O-benzylidene)-2,6-dideoxy-- L--galacto(gluco)furanose is shown below:</p>

Stachyose hydrate is a methylated, custom-synthesized, click-modified oligosaccharide that is used as a synthetic complex carbohydrate. It is synthesized from the saccharide stachyose by fluorination and modification with methyl groups. This product may be used in biological research or as a fluoropolymer precursor. Stachyose hydrate has been shown to have high purity and can be modified to contain monosaccharides and sugars.

<p>5'-O-(2-Amino-2-deoxy-D-glucopyranosyl)-thymidine is a custom synthesis of saccharide that is fluorinated, methylated, and monosaccharide. This compound has been modified with a click modification and an oligosaccharide. The saccharide is glycosylated with sugar and Carbohydrate. 5'-O-(2-Amino-2-deoxy-D-glucopyranosyl)-thymidine has CAS No. 631842-24-5</p>

<p>Chitotriose undecaacetate is a synthetic substrate that is used in transfecting experiments. It has high sensitivity and can be used to introduce nucleic acid into cells. Chitotriose undecaacetate is used as a synthetic fluorometric assay for the determination of chitinase activity in vitro or as a substrate for cell-free synthesis of nucleic acids. It has been shown to possess moieties that are sensitive to hydrogen chloride and chloride ions, making it an effective probe for the determination of these ions. Chitotriose undecaacetate also reacts with sephadex G-200, which makes it useful for separating DNA fragments by electrophoresis.</p>

<p>3,5-Dideoxy-3,5-imino-1,2-O-isopropylidene-N-benzyl-6-O-tert.butyldimethylsilyl-b-L-galactofuranose is a synthetic glycosylation agent that can be used in the synthesis of complex carbohydrate molecules. This compound is fluorinated and saccharide modified with methyl groups at the 3 and 5 positions. The final product has a purity of &gt;99% and CAS No. 614734–05–0.</p>

Trehalose hexaacetate is a polysaccharide that is used as a food additive. It has been shown to be a potent inhibitor of methylation and fluorination, which are post-translational modifications that are important for the function of proteins. Trehalose hexaacetate also has a high degree of glycosylation, which makes it an excellent candidate for complex carbohydrate synthesis. The compound can be custom synthesized with high purity and at low cost.

Deoxy-L-fructose is a sugar that is synthesized by the cleavage of sucrose, which is a disaccharide composed of glucose and fructose. Deoxy-L-fructose can be obtained from the hydrolysis of sucrose or it can be synthesized by the hydrogenation of d-talitol. This compound is used in various industrial processes as an intermediate in the production of other sugars and alcohols. 1-Deoxy-L-fructose has been found to have antimicrobial properties against Enterobacter aerogenes, Lactobacillus plantarum, and Lactobacillus acidophilus. It also inhibits the growth of Escherichia coli (E. coli) bacteria when tested in vitro at concentrations between 0.2 and 2mM. The antibiotic activity against E. coli may be due to its ability to inhibit ribosome synthesis and protein synthesis in these cells

3,6-Anhydro-D-glucose is a compound that is produced by the dehydration of D-glucose. It has been synthesized in an acidic hydrolysis reaction involving mercaptoacetic acid and sodium carbonate. The synthesis of 3,6-Anhydro-D-glucose involves the use of chloride as a reactive agent and metal ion catalysis. This compound can be used to create isomers with other sugars. It also has supramolecular chemistry properties due to its ability to form complexes with other molecules.

<p>1,4-Anhydro-6-chloro-6-deoxy-D-glucitol is a complex carbohydrate that has been fluorinated and modified with methyl groups. It can be custom synthesized to produce high purity compounds. 1,4-Anhydro-6-chloro-6-deoxy-D-glucitol is used in synthesis of saccharides and oligosaccharides. The compound has been modified with Click chemistry to produce glycosylation products. It can also be used as an intermediate for the synthesis of sugar derivatives.<br>1,4-Anhydro-6-chloro-6-deoxy--D--glucitol has the following chemical structure:</p>

<p>Methyl a-D-xylopyranoside is an iron chelator that can be used as a mycobacterial drug candidate. It binds to both ferric and ferrous iron, and has been shown to inhibit the uptake of ferric iron by Mycobacterium tuberculosis. It also inhibits the synthesis of siderophores, which are molecules produced by bacteria in order to acquire iron from their environment. Methyl a-D-xylopyranoside does not bind to the alpha-d-glucopyranoside moiety typically found in iron complexes. This is due to its hydroxamate group, which causes it to have an increased affinity for Fe3+. This compound is active against gram negative bacteria such as E. coli and Salmonella enterica serovar Typhimurium, but not against gram positive organisms such as Staphylococcus aureus or Streptococcus pneumoniae.</p>

<p>1,2-ene-glucose is a methylated glucose that can be custom synthesized. It has been modified with a click modification and fluorination. It is an Oligosaccharide and Polysaccharide that is used as a Carbohydrate in the synthesis of complex carbohydrates. The purity of 1,2-ene-glucose is high and it can be modified with Monosaccharides or sugar.</p>

<p>5,6-O-Isopropylidene-3-C-methyl-D-mannono-1.4-lactone is a fluorinated monosaccharide that can be modified with other chemicals to create a variety of products. This chemical is used in the synthesis of oligosaccharides and polysaccharides. 5,6-O-Isopropylidene-3-C-methyl-D-mannono-1.4-lactone has a CAS number of 105853-. It has been shown to be high purity and is also available for custom synthesis. 5,6--O--isopropylidene--3--C--methyl--D--mannono--1.4--lactone can be synthesized from methylation, click modification, and fluorination reactions on glycolaldehyde.</p>

<p>2-Deoxy-2-fluoro-D-glucose 6-phosphate barium salt is a glucose analogue used in positron emission tomography (PET) imaging of cancer. It is an inhibitor of glycolysis and phosphofructokinase, which are enzymes that catalyze the conversion of glucose to pyruvate. 2-Deoxy-2-fluoro-D-glucose 6-phosphate barium salt is taken up by the cell by active transport, then metabolized into 2 deoxy 2 fluoro D mannose phosphate and finally converted to glucosylceramide. The PET scan detects the accumulation of this molecule in cells with high glycolytic activity, such as cancer cells. This compound has been shown to inhibit hepatocellular carcinoma (HCC) cell growth in vitro and in vivo.</p>

<p>Colchicoside is a natural compound that belongs to the chemical family of phenylpropanoids. It is used in the treatment of gout and pseudogout, and has been shown to be effective against demecolcine-induced hemolytic activity. Colchicoside has also shown to be an analog for other compounds with toxicological studies, such as hydrochloric acid and potassium dichromate. The toxicity studies performed on colchicoside have shown that it can cause damage to cells in culture by inhibiting DNA repair mechanisms.</p>

<p>Konjac glucomannan is an acetylated (1,4)-β-D-glucomannan obtained from the tubers of Amorphophallus konjac or Konnyaku root. It is widely used in foods, pharmaceuticals paints and explosives. It has been shown that ternary mixtures of konjac glucomannan, xanthan gum and sodium alginate can form a non-covalently linked complex which exhibits enhanced rheological properties of value in, for example, functional foods.</p>

5-O-Tert.butyldimethylsilyl-2- C-methyl-D-arabinonic acid g-lactone is a methylated arabinose derivative that has been synthesized from 2,6,8,10,12,14,16-hexadecanoyloxybenzyl alcohol and tert.butyldimethylchlorosilane in a two step process. It can be used as an intermediate for the synthesis of oligosaccharides and polysaccharides with various modifications. 5-O-Tert.butyldimethylsilyl-2- C-methyl-D-arabinonic acid g -lactone is available at a purity of > 98% and contains no other contaminants such as sugar or monosaccharide.

Component of glycoproteins and glycolipids expressed in antigens and receptors of proteins, bacteria and viruses. Found in the free form in human biofluids, including urine and milk - preventing adhesion of bacteria to urinary epithelium and inhibiting enteric pathogens respectively. An efficient inhibitor of neutrophil-activating protein of H.pylori (HPNAP)-mediated neutrophil activation.

<p>2,3,4,6-Tetra-O-acetyl-b-D-galactopyranosyl ethylxanthate is a carbohydrate that has been modified through the process of fluorination and methylation. It is a synthetic compound that has been custom synthesized to produce high purity. The CAS number for this compound is 56923-48-8. This compound is used in the modification of saccharides and oligosaccharides as well as other sugar compounds. 2,3,4,6-Tetra-O-acetyl-b-D-galactopyranosyl ethylxanthate is also glycosylated and click modified.</p>

<p>Methyl 3-azido-3-deoxy-2,4-di-O-acetyl-b-D-xylopyranoside is a synthetic compound that can be used in glycosylation reactions to introduce an azido group at the reducing end of a glycose. This product has been shown to react with the thiol group on cysteine residues and undergoes click chemistry with maleimide groups. It is also useful for the synthesis of polysaccharides and oligosaccharides. The purity of this product is over 99%.<br>Methyl 3-azido-3-deoxy-2,4,-di-(O)-acetyl -b-(D)-xylopyranoside</p>