Glycosciences

<p>Trehalose-6,6'-dibehenate (TDB) is a novel synthetic lipid that has been shown to have beneficial effects in the treatment of inflammatory bowel disease. This compound may act as an anti-inflammatory agent by inhibiting toll-like receptor 4 (TLR4)-mediated signaling and TLR4-dependent production of proinflammatory cytokines. TDB also inhibits HIV infection by interfering with CD4+ T cell function and decreasing the number of CD4+ cells in the gut. In addition, TDB has been shown to be effective against lps-induced inflammatory response in cell culture.</p>

<p>2-Acetamido-2-deoxy-D-glucono-1,5-lactone is a diagnostic agent that inhibits the activities of enzymes such as protein synthesis and cell division. It can be used to identify viral infections in animals, plants and marine microorganisms. 2-Acetamido-2-deoxy-D-glucono-1,5-lactone has been shown to inhibit the biochemical activity of enzymes in cells grown in culture. 2AADG is also a diagnostic agent that can be used to detect tumors in subcutaneous tissues due to its ability to inhibit the production of proteins essential for cell division.</p>

<p>5-Azido-5-deoxy-2,3-O-isopropylidene-D-ribono-1.4-lactone is a synthetic glycosylate with a fluorinated sugar. It is custom synthesized to order and can be modified with methylation, monosaccharide, or polysaccharide modifications. The CAS number of 5-Azido-5-deoxy-2,3 -O -isopropylidene -D -ribono -1.4 -lactone is 84762–27–6.</p>

<p>Ex starch-partial hydrolysis,food ingredient, moderatly sweet, easily digested</p>

<p>L-Mannonic acid-1,4-lactone is an acidic compound that has kinetic properties. It is used in the assays of chloride ions and neutral pH. L-Mannonic acid-1,4-lactone also has conjugates with hydrolytic activity and can be used as a synthetic intermediate for other organic compounds. L-Mannonic acid-1,4-lactone can be found in group P2 of the periodic table because it contains a hydroxyl group and an organic group with a methyl ethyl side chain. L-Mannonic acid-1,4-lactone hydrolyzes at high temperatures and may exhibit synergistic effects when combined with other agents. This product is also used to incubate cells such as k562 cells.</p>

<p>2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-galactopyranose is a sugar that is used in the synthesis of glycosides and other carbohydrate derivatives. It can be modified with various groups to produce new compounds. This product is an important raw material for the synthesis of saccharides and oligosaccharides with specific properties.</p>

<p>2,3-O-Isopropylidene-1,4-di-C-methyl-L-erythrofuranose is a fluorinated monosaccharide. It is synthesized by the reaction of 2,3-O-isopropylidene L-erythroascorbic acid with sodium difluoromethanesulfinate in toluene under refluxing conditions. It can be used as an intermediate for the preparation of oligosaccharides and polysaccharides. This product has been shown to be resistant to degradation by enzymes such as glycosidases and esterases. It also has a high purity level and can be used for custom synthesis projects.</p>

<p>4-Methoxyphenyl 3,4-di-O-benzyl-a-D-mannopyranoside is a glycosylated, complex carbohydrate with a methylated and fluorinated saccharide. This product is available for custom synthesis and can be ordered in high purity.</p>

<p>The compound is an oligosaccharide with a complex carbohydrate. The product is custom synthesized and has been modified by fluorination. It is a high purity, synthetic monosaccharide sugar that is methylated.</p>

Methyl 2-O-(a-D-mannopyranosyl)-b-D-mannopyranoside is a glycosylation product of mannose and glucose. It is an intermediate in the synthesis of the complex carbohydrate, methylated mannan. This compound is also an intermediate in the synthesis of saccharides with a fluorinated sugar moiety. Methyl 2-O-(a-D-mannopyranosyl)-b-D-mannopyranoside can be custom synthesized to meet your needs.

<p>6-Deoxy-D-altritol is a structural analysis of a polysaccharide carbohydrate that is found in the cell walls of asteroides. It has been shown to contain mannose, d-arabinose, and d-glucose residues. 6-Deoxy-D-altritol also contains galactosyl and phosphate groups. The backbone of 6-Deoxy-D-altritol is made up of phosphodiester bonds with a d-galactose skeleton. This molecule can be used for the identification and characterization of bacteria species such as Mycobacterium tuberculosis and Mycobacterium avium complex.</p>

<p>Blood group H type II trisaccharide is a carbohydrate that is modified with a spacer-biotin conjugate. It can be used in the synthesis of oligosaccharides and saccharides. This product has been fluorinated, has high purity, and is custom synthesized to order. The product also has methylation, glycosylation, and click modification.</p>

<p>2-O-a-D-Glucopyranosyl-D-galactopyranose is a synthetic monosaccharide that can be used as a glycosylate building block in the synthesis of oligosaccharides. It has been fluorinated, methylated, and click modified. This high purity material is available for custom synthesis. 2-O-a-D-Glucopyranosyl-D-galactopyranose is also known by its CAS number 7368-73-2.</p>

<p>Key synthetic precursor for the synthesis of lacto-oligosaccharides</p>

<p>4-Aminophenyl b-D-glucuronide sodium is a glycosylation reagent used in the synthesis of complex carbohydrates, polysaccharides and oligosaccharides.</p>

<p>2-Azido-2-deoxy-3,5-O-benzylidene-D-xylono-1,4-lactone is a synthetic sugar that is used in the synthesis of glycosylation, methylation and click modification reactions. It has been shown to be a potential precursor for polysaccharides and fluorinated saccharides. This product can be custom synthesized and is available at high purity.</p>

<p>b-D-Glucose-1-phosphate disodium salt is a white crystalline powder that is soluble in water, ethanol, and acetone. It is a monosaccharide with the molecular formula C6H12O6P2Na2. It has a molecular weight of 348.08 g/mol.</p>

<p>2,3,4,6-Tetra-O-benzyl-D-mannopyranosyl fluoride is a glycosylamine that has been synthesized from l-threonine. The chemical structure of this compound can be classified as a pyranose sugar with an O-methylated benzyl group at the C2 position. This sugar is synthesized by reductive cleavage of the methyl ether and subsequent reaction with sodium borohydride. The conformational analysis of the molecule was performed using molecular mechanics calculations and quantum mechanical simulations. In addition, electron paramagnetic resonance (EPR) experiments were conducted to determine the chemical shift in the 1H NMR spectrum and to identify the acceptor or donor in the molecule. Trichloroacetimidates are used as monomers for this type of synthesis because they provide good yields and can be easily prepared by reacting chloroacetic acid with chloral hydrate.</p>

<p>Starch breakdown product; sweetening agent; fermentable intermediate in brewing</p>

<p>Anhydrous lactose is an excipient, filler, diluent, and bulking agent in a wide variety of pharmaceutical tablets, capsules, powders and other preparations. It also has applications as a nutrient and multi-functional ingredient in infant formulae, geriatric, dietetic and health foods and may be used as an ingredient in culture media.</p>

<p>Alpha-cyclodextrin (α-CD) derivative with a hydrophilic exterior and lipophilic cavity (smaller than β-CDs and γ-CDs) to allocate certain guest molecules. This structural characteristic enables applications in molecular encapsulation, solubility enhancement, and stabilization across multiple industries. In pharmaceuticals, it serves as a drug delivery vehicle, enhancing the bioavailability and stability of active ingredients. The food industry utilizes it as a stabilizer for flavors, colors, and nutrients, as well as a functional ingredient for its effects on lipid metabolism. In cosmetics, it acts as a complex agent for fragrances and active components. Its applications extend to analytical chemistry for chiral separation and to materials science for developing smart materials and nanosystems.</p>

<p>Isomaltol is a sugar alcohol that is used as a food additive. It is a white, crystalline powder that is soluble in water and has an intense sweet taste. Isomaltol is produced by hydrogenating the reducing ends of sucrose to form maltose, which then undergoes hydrolysis to form maltitol. Isomaltol can be used as a replacement for sugar in foods and drinks. Isomaltol has been shown to inhibit tyrosinase activity, which may be beneficial for skin care products. It also has antimicrobial properties due to its ability to react with aluminium ions.</p>

2-Acetamido-2-deoxy-beta-D-glucopyranosyl amine (A2DG) is a diagnostic marker for juvenile idiopathic polyarteritis nodosa. This molecule is an intermediate in the synthesis of the carbohydrate, heparin. The A2DG assay measures concentrations of this metabolite in plasma samples and can be used to diagnose vasculitis and other inflammatory diseases. Novartis has developed a metabolite profiling technique that uses mass spectrometry to identify molecules present in cell culture or plasma samples. This technique has been used to measure levels of A2DG metabolites in patients with vasculitis, including juvenile idiopathic polyarteritis nodosa.

2-C-Methyl-3,5-O-(di-tert.butylsilylidene)-D-xylono-1.4-lactone is a synthetic, fluorinated oligosaccharide that is custom synthesized with high purity and a CAS Number. It has been modified with a click chemistry reaction to create an Oligosaccharide sugar. This complex carbohydrate can be used in the synthesis of glycosylation reactions, methylation reactions and monosaccharide reactions.

2,3,4,6-Tetra-O-acetyl-a-D-glucopyranosyl fluoride is a halide with the chemical formula of F. It has an axial conformation and is a crystalline solid at room temperature. 2,3,4,6-Tetra-O-acetyl-a-D-glucopyranosyl fluoride reacts with water to form hydrofluoric acid (HF). This compound is an important reagent in carbohydrate analysis because its presence or absence can be used to distinguish between the two anomers of maltose: α-(1→2) and β-(1→4). It also reacts with sodium chloride to give the chloride salt sodium tetrafluoroborate. The molecule has three substituents: a hydroxymethyl group (-OH), a glycosidic oxygen atom (O), and a glucosyl group (-CHO). Watanabe's numbering system for

<p>Starting material for chiral-pool based organic synthesis</p>

<p>Allyl α-D-mannopyranoside (AAM) is a custom synthesis that can be used in the modification of oligosaccharides and polysaccharides. It is also a monosaccharide with a methylation and glycosylation pattern that can be used for Click modification. AAM has been fluorinated to provide high purity and is synthesized from allyl alcohol, acetone, and hydrochloric acid.</p>

<p>L-Mannitol is a sugar alcohol that is an important component of pharmaceutical preparations. It is used as a preservative, diluent, and sweetener in many pharmaceutical products. L-Mannitol has been shown to have anti-inflammatory properties and may help prevent allergic reactions by inhibiting the production of prostaglandin D2. L-Mannitol also inhibits the activity of xylitol dehydrogenase, which prevents the conversion of xylitol to DHA, an intermediate metabolite that can cause tissue damage in animals and humans. L-Mannitol has been shown to have a laxative effect when taken orally or injected as an intravenous solution. This property may be due to its ability to stimulate chloride secretion from intestinal cells and increase water reabsorption from the colon. L-Mannitol is also used as a chromatographic matrix for saponins and conjugates with other amino acids.</p>

<p>Laminaran is a polysaccharide that co-occurs with fucoidan and alginate in brown seaweeds such as Laminaria digitata, Laminaria cloustoni, Eisenia bicyclis and Thallus laminariae. It is a β-1,3-linked glucan which it is claimed stimulates the immune system in mammals and fish.<br>The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.</p>

<p>Methyl (phenyl 2,3-di-O-benzyl-1-thio-b-D-glucopyranoside)uronate is a synthetic glycosylation product. It is the methyl ester of 2,3,4,6-tetra-O-benzylated glucuronic acid. This product can be used for the modification of polysaccharides and saccharides with click chemistry. The synthesis of this compound can be customized to meet your needs.</p>

<p>4-Methoxyphenyl 3,4-di-O-benzyl-2,6-di-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-a-D -mannopyranoside is a synthetic glycoside that can be custom synthesized to order. It is considered to be of high purity with a CAS number 58314−10−1. This product has been fluorinated and glycosylated and is synthetically produced. 4MPBP has the following modifications: methylation, modification, and glycosylation. 4MPBP is an oligosaccharide that is composed of saccharides and a complex carbohydrate.</p>

<p>Fucosyloligosaccharide present in human milk and colostrum</p>

<p>Inhibitor that targets cellulase enzymes engaged in the degradation of cellulose.</p>

<p>1-O-Methyl-beta-D-xylopyranoside is a matrix component that is used as an artificial sweetener. This product has been shown to have the ability to protect cells against radiation and toxic chemicals. 1-O-Methyl-beta-D-xylopyranoside also inhibits the growth of coliform bacteria by inhibiting their energy metabolism and may be used for wastewater treatment. It has been shown to be effective in analytical methods to identify the presence of human feces in water samples.</p>

<p>N-Glycolylneuraminic acid-OVA is a custom synthesis that is an Oligosaccharide. It is Polysaccharide and Modification, saccharide, Methylation, Glycosylation, Click modification, Carbohydrate, sugar. The product has a CAS No., has a purity of ≥ 95%, and is Fluorination, Synthetic.</p>

<p>Hesperetin 7-O-b-D-glucuronide is a metabolite of hesperetin, a flavonoid primarily sourced from citrus fruits. This compound is formed through the glucuronidation process, a metabolic pathway that modifies hesperetin to enhance its solubility and facilitate its excretion from the human body. Hesperetin 7-O-b-D-glucuronide exerts biological effects through various modes of action, including antioxidant and anti-inflammatory mechanisms. It is thought to scavenge free radicals and modulate inflammatory pathways by inhibiting specific enzymes and cytokines.In scientific research, Hesperetin 7-O-b-D-glucuronide is studied for its potential therapeutic applications, particularly its role in reducing oxidative stress and inflammation-related diseases. It has garnered attention in the context of cardiovascular health, neuroprotection, and metabolic disorders. The exploration of its bioavailability and specific interactions at the molecular level continues to provide insights into its promising applications in nutraceuticals and pharmaceuticals. Researchers investigate its efficacy and safety to better understand its potential role in disease prevention and therapy.</p>

<p>D-Galactosamine-1-phosphate is a precursor of UDP-glucose and is used in the synthesis of fatty acids. D-Galactosamine-1-phosphate is synthesized by the enzyme UDP-glucose pyrophosphorylase, which catalyzes the reaction between UDP and D-galactose. It is expressed in strains that have been engineered to produce recombinant proteins. This product can be produced in vitro by a number of methods, including enzymatic or chemical synthesis. The enzyme activity of D-galactosamine 1 phosphate synthase is temperature dependent, with optimal activity at 40°C. This product has been shown to inhibit hepatitis virus production and lipid formation in vitro.</p>

<p>Ethyl β-D-glucuronide (EBG) is a metabolite of ethanol that is formed by the conjugation of glucuronic acid to ethanol in the liver. EBG has been shown to be a potential biomarker for alcohol consumption, as it can be detected in urine and blood. The presence of this molecule has also been associated with an increased risk of developing type 2 diabetes mellitus, cardiovascular disease, and cancer. EBG may also have pharmacological effects as it has been shown to inhibit lipid oxidation and increase insulin sensitivity. This molecule can be extracted from human serum using solid phase microextraction</p>

D-Erythrulose is a sugar that can be synthesized from the chemical structures of glycolaldehyde and carbonyl group. It can also be produced by hydrolysis of erythritol, which is found in plant cell walls. D-Erythrulose has been used as an alternative to glucose for fermentation processes because it does not inhibit the growth of most bacteria. D-Erythrulose has been shown to increase ATP levels in Escherichia coli K-12 cells and to affect the activities of enzymes involved in glycolysis, such as glyceraldehyde 3-phosphate dehydrogenase, phosphoglycerate kinase, and enolase. The metabolic pathways that produce D-erythrulose are found in many organisms, including Corynebacterium glutamicum, Brucella melitensis, and Brucella suis.

<p>3-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-D-mannopyranose is a disaccharide that is part of the glycosaminoglycan family. It has an antigenic epitope that is recognized by antibodies, which are found in patients with rheumatoid arthritis and other autoimmune diseases. 3-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-D-mannopyranose is also known as glucosamine.</p>

<p>Galactose from plant origin, animal free production</p>

<p>Substrate for arabitol dehydrogenase enzyme</p>

<p>Glucose 6-phosphatase substrate</p>

<p>1-O-tert-Butyldimethylsilyl-5-O-DMT-2-O-methyl-D-ribose 3-CE phosphoramidite is a methylated saccharide which can be used in the synthesis of polysaccharides. This product is custom synthesized and has high purity, with a CAS number of 138876-62-1. It is also fluorinated, and can be used for complex carbohydrate synthesis.</p>

2-Deoxy-2-fluoro-D-glucose 6-phosphate dipotassium is a fluorinated sugar that is used as a building block in the synthesis of complex carbohydrates. 2-Deoxy-2-fluoro-D-glucose 6-phosphate dipotassium can be modified to produce glycosylations, methylations, and click chemistry modifications. This product is sold as a custom synthesis and can be used for any desired modification.

<p>Formononetin-b-D-glucuronide sodium salt is a synthetic compound that is commonly used as a building block in the synthesis of oligosaccharides and polysaccharides. Formononetin-b-D-glucuronide sodium salt is also known to be an inhibitor of human DNA polymerase alpha, which has been shown to inhibit the replication of human immunodeficiency virus (HIV) and herpes simplex virus type 1 (HSV1). Formononetin-b-D-glucuronide sodium salt has high purity, with a purity level of &gt;99%.</p>

<p>(1S) -1- [(2S, 3S,4R) -N-Butyl-4-hydroxymethyl-3- hydroxy- 1- azetidinyl] -1, 2- ethanediol is a synthetic monosaccharide that belongs to the group of complex carbohydrates. It has been modified by fluorination and methylation. This product can be synthesized according to customer specifications. The CAS number for this product is 97911-51-7. It is highly pure with a purity level of 98%. This product can be glycosylated or click modified according to customer specifications.</p>

<p>2'-Azidoethyl a-mannopyranoside is a synthetic monosaccharide that is used as a building block for the synthesis of oligosaccharides and polysaccharides. This product has been custom synthesized for your specific needs. It is an off-white powder with purity greater than 99%. The methylation of this compound can be achieved by reacting it with sodium methoxide in methanol, followed by hydrolysis with sodium hydroxide. The azido group can also be converted to an acetyl group by reaction with acetic anhydride in pyridine.</p>

<p>Isosorbide dinitrate is a drug that belongs to the class of nitrates. It is used in the treatment of angina pectoris, as well as congestive heart failure and chronic heart failure. Isosorbide dinitrate has been shown to cause caspase-independent cell death in human leukemia cells and breast cancer cells. This may be due to its ability to inhibit mitochondrial membrane potential and interfere with intracellular calcium mobilization. The optimum concentration for isosorbide dinitrate is 10 µM, which inhibits the growth of bacteria, including Mycobacterium tuberculosis and Salmonella enterica serovar Typhimurium. The drug also inhibits the production of proinflammatory cytokines such as IL-1β, IL-6, and TNF-α by inhibiting c-jun phosphorylation. Isosorbide dinitrate also has anti-inflammatory properties, which may be due to its ability to inhibit 4-hyd</p>

<p>D-Glucosamine-oxime HCl is a hydrocyanic acid derivative that contains a polyhydroxy group. It can exist as two isomers, D-glucosamine and D-glucosamine-oxime. These isomers are distinguished by the presence or absence of acetyl groups on the nitrogen atoms. D-Glucosamine-oxime HCl functions as a divalent metal ion chelator and sequestering agent that has been shown to be useful in the treatment of lead poisoning. It also has been used in the synthesis of hydrocyanic acid, which is an important chemical for organic synthesis.END&gt;</p>